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The map label for this gene is ftsW [H]

Identifier: 91786972

GI number: 91786972

Start: 1106467

End: 1107729

Strand: Direct

Name: ftsW [H]

Synonym: Bpro_1074

Alternate gene names: 91786972

Gene position: 1106467-1107729 (Clockwise)

Preceding gene: 91786971

Following gene: 91786973

Centisome position: 21.28

GC content: 62.07

Gene sequence:

>1263_bases
GTGACCGTGGCTGCACGCTTTTGGGGTTGGCTTTCCGGTCTCGGCGGCGTCGGCGCGGTCGCCGCGGATGTGCTGCCCGT
TCGCCTCGGGCGGCAGAGCCTGTCCCGAAGCCCGGCTGCGCCTGTTCGCATGGCGGGGTTTGACCAGGCGCTGGTCTGGG
TGACGGTGGCCTTGCTCATGTGGGGTTTGGTCATGGTGTATTCGGCGTCGGTGGCGATGCCCGACAACCCCAAGTTTTCC
CGCTATGCGCACACGCATTTCCTGCTGCGTCATGTGCTGTCGCTGGTGGTGGCTTTCATCGTGGCATTCCTGGCGTTTCA
GGTTCCCATGGCGACATGGGAAAAGCTGGCGCCCTGGCTGTTTGTGCTGTCCCTGCTGCTGCTGATGCTGGTGCTGCTGC
CCTTTATCGGCAAGGGCGTCAATGGCGCGCGACGCTGGATTTCAATGGGTTTCATGAATTTCCAGCCTTCGGAACTGGCG
AAATTCGCGGTGCTGCTGTACGCCTCGGATTACATGGTTCGCAAGATGGAAGTCAAAGAGCGCTTCTTCCGCGCTGTCAT
GCCCATGGCGGTGGCGATTGCGGTCGTCGGCCTGCTGCTGCTGGCCGAGCCTGACATGGGCGCTTTCATGGTGATCTCGG
TCATCGCGATGGGCATCCTCTTTCTCGGCGGCGTCAATGCGCGCATGTTCTTCGTGATTGCGGCCGTGGTGGTGGTCGCC
TTTGGCCTGATGGTGATGCTCAGCGAATGGCGCCGCGAGCGGATTTTTGCCTACCTGGATCCCTGGAGCGACAAGTACTC
CATGGGCAAAGGCTACCAGTTGTCGCATTCGCTGATTGCTTTCGGGCGCGGCGAGATTTTTGGCGTGGGCCTGGGCGGCA
GCATCGAAAAGCTGCACTGGCTGCCCGAGGCGCACACCGACTTCCTGATGGCCGTGATCGGCGAAGAGTTCGGCCTGCTG
GGTGTGCTCGTGGTGATTGGCCTGTTCATGTGGATGACCCGCCGCATCATGCACATCGGCCGCCAGTCGATCGCGCTGGA
CCGCCTGTTTGCCGGGCTGGTGGCCCAGGGCGTCGGCATCTGGATGGGTTTCCAGACCTTCATCAACATCGGCGTGAATC
TCGGTGCCTTGCCCACCAAGGGCCTGACCCTGCCGCTGATGAGCTACGGCGGCTCGGCCATTTTGATGAACCTGATTGCC
TTGGCCGTGGTGCTGCGGATTGACTACGAGAATCGCACCCTGATGCGTGGGGGGCGGGCATGA

Upstream 100 bases:

>100_bases
CCGCCTGCGCCAGTTTTGACATGTTTGACAACTACGAACACCGCGCCCAGGTCTTTTGTGATGCGGTGCAGGCGCTGGCC
CAGGAACAGGGGGTGGTGCT

Downstream 100 bases:

>100_bases
GCGAGCATGTGCGTAGCGCCGGGCCGCCCCAAGCAAGCACGGCCCCCTCGGGGGGCAGCGCAGTACACGAAGTGACAAGC
GTGGGGGCTCGCGTAGCTTT

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTVAARFWGWLSGLGGVGAVAADVLPVRLGRQSLSRSPAAPVRMAGFDQALVWVTVALLMWGLVMVYSASVAMPDNPKFS
RYAHTHFLLRHVLSLVVAFIVAFLAFQVPMATWEKLAPWLFVLSLLLLMLVLLPFIGKGVNGARRWISMGFMNFQPSELA
KFAVLLYASDYMVRKMEVKERFFRAVMPMAVAIAVVGLLLLAEPDMGAFMVISVIAMGILFLGGVNARMFFVIAAVVVVA
FGLMVMLSEWRRERIFAYLDPWSDKYSMGKGYQLSHSLIAFGRGEIFGVGLGGSIEKLHWLPEAHTDFLMAVIGEEFGLL
GVLVVIGLFMWMTRRIMHIGRQSIALDRLFAGLVAQGVGIWMGFQTFINIGVNLGALPTKGLTLPLMSYGGSAILMNLIA
LAVVLRIDYENRTLMRGGRA

Sequences:

>Translated_420_residues
MTVAARFWGWLSGLGGVGAVAADVLPVRLGRQSLSRSPAAPVRMAGFDQALVWVTVALLMWGLVMVYSASVAMPDNPKFS
RYAHTHFLLRHVLSLVVAFIVAFLAFQVPMATWEKLAPWLFVLSLLLLMLVLLPFIGKGVNGARRWISMGFMNFQPSELA
KFAVLLYASDYMVRKMEVKERFFRAVMPMAVAIAVVGLLLLAEPDMGAFMVISVIAMGILFLGGVNARMFFVIAAVVVVA
FGLMVMLSEWRRERIFAYLDPWSDKYSMGKGYQLSHSLIAFGRGEIFGVGLGGSIEKLHWLPEAHTDFLMAVIGEEFGLL
GVLVVIGLFMWMTRRIMHIGRQSIALDRLFAGLVAQGVGIWMGFQTFINIGVNLGALPTKGLTLPLMSYGGSAILMNLIA
LAVVLRIDYENRTLMRGGRA
>Mature_419_residues
TVAARFWGWLSGLGGVGAVAADVLPVRLGRQSLSRSPAAPVRMAGFDQALVWVTVALLMWGLVMVYSASVAMPDNPKFSR
YAHTHFLLRHVLSLVVAFIVAFLAFQVPMATWEKLAPWLFVLSLLLLMLVLLPFIGKGVNGARRWISMGFMNFQPSELAK
FAVLLYASDYMVRKMEVKERFFRAVMPMAVAIAVVGLLLLAEPDMGAFMVISVIAMGILFLGGVNARMFFVIAAVVVVAF
GLMVMLSEWRRERIFAYLDPWSDKYSMGKGYQLSHSLIAFGRGEIFGVGLGGSIEKLHWLPEAHTDFLMAVIGEEFGLLG
VLVVIGLFMWMTRRIMHIGRQSIALDRLFAGLVAQGVGIWMGFQTFINIGVNLGALPTKGLTLPLMSYGGSAILMNLIAL
AVVLRIDYENRTLMRGGRA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=379, Percent_Identity=41.4248021108179, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1786853, Length=332, Percent_Identity=33.1325301204819, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46247; Mature: 46116

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure 
TVAARFWGWLSGLGGVGAVAADVLPVRLGRQSLSRSPAAPVRMAGFDQALVWVTVALLM
CCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHCCCCCCCEECCCCHHHHHHHHHHHHH
WGLVMVYSASVAMPDNPKFSRYAHTHFLLRHVLSLVVAFIVAFLAFQVPMATWEKLAPWL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FVLSLLLLMLVLLPFIGKGVNGARRWISMGFMNFQPSELAKFAVLLYASDYMVRKMEVKE
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RFFRAVMPMAVAIAVVGLLLLAEPDMGAFMVISVIAMGILFLGGVNARMFFVIAAVVVVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FGLMVMLSEWRRERIFAYLDPWSDKYSMGKGYQLSHSLIAFGRGEIFGVGLGGSIEKLHW
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCHHHHHC
LPEAHTDFLMAVIGEEFGLLGVLVVIGLFMWMTRRIMHIGRQSIALDRLFAGLVAQGVGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMGFQTFINIGVNLGALPTKGLTLPLMSYGGSAILMNLIALAVVLRIDYENRTLMRGGRA
HHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]