Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 91786970

GI number: 91786970

Start: 1103489

End: 1104703

Strand: Direct

Name: mraY [H]

Synonym: Bpro_1072

Alternate gene names: 91786970

Gene position: 1103489-1104703 (Clockwise)

Preceding gene: 91786969

Following gene: 91786971

Centisome position: 21.22

GC content: 60.33

Gene sequence:

>1215_bases
ATGCCTCCTTCGAGGCGGTTCGGCAGGAGGCATTTCATGCTGCTTAGCCTGGCCCAGTGGCTCCAGTCGATTTCCCCTGA
ATTCGGATCTTTCCGGGTGTTCCAGTACCTGACATTTCGCGCTGTCATGGCCGCGCTCACGGCGCTGCTGATTGGCCTGC
TGGCCGGGCCGTTTGTCATTCGCCGGCTGATCTCGCTGAAGATCGGTCAGCCGATCCGCGAATACGCGATGCAGACACAC
CTGAGCAAGAGCGGAACGCCCACCATGGGTGGCGTGCTGATCCTGATGTCCATCGGCATTTCGACCCTGCTGTGGTTTGA
CCTGTCCAACCGCTTCGTGTGGATTGTGCTGCTCGTCACCCTGGGATTCGGTGCCATCGGCTGGGCCGACGACTGGCGCA
AGGTCGTGCTGAAAGATCCTGAAGGCATGCGGTCGCGTGAAAAATACCTGTGGCAATCACTGATTGGCCTGGTGGCGGCG
CTCTACCTGGTGTTCAGCATCTCGGAGAGTTCCAATCTGCGCGTGCTGGAATTGTTTTTCAGCTGGGTGCAGTCGGGATT
TGACGTCGACCTGCCGCCCAAGGCCGGCTTGCTGGTGCCCTTCGTGAAGGAAATCAGTTACCCGCTGGGCGTATTCGGTT
TTGTGATCCTGACCTACCTGGTGATTGTGGGTTCGAGCAATGCCGTCAACCTGACCGACGGCCTGGACGGCCTGGCCATC
ATGCCGGTGGTCATGGTGGGGTCCGCCCTGGGCGTGTTCGCCTATGTAACCGGCAGCGCGGTCTATTCCAAATACCTCTT
CTTTCCGCACATTCCCGGCTCCGGTGAACTGCTGATCTTCTGCTCGGCCATGGCGGGTGCCGGGCTGGCGTTCCTGTGGT
TCAACACGCACCCGGCTCAGGTGTTCATGGGTGACGTCGGCGCGCTGGCGCTGGGGGCGGCGCTGGGCACCATCGCCGTC
ATCGTGCGCCAGGAAATTGTGCTGGCCATCATGGGCGGGATTTTTGTCGTTGAGGCCCTGTCCGTGATGATGCAGGTGAT
CTGGTTCAAGTACACCAAGAAGCGCTACGGCGAAGGCCGGCGCCTCTTCAAGATGGCGCCGCTGCACCACCACTTCGAGA
AAAGCGGCTGGAAGGAGACCCAGGTGGTCGTCCGCTTCTGGATCATCACCATGCTGCTGTGCCTGGTGGGTCTCTCAACG
TTGAAGCTCAGGTAA

Upstream 100 bases:

>100_bases
GGAGCAGGTGGTTCAGGTCATCGCAGATCACACAAAAAACTACAAGGAAGAAACATGAGCCCCCATGCTCACATGCGTTC
GCTGTCCCATCAGGGGGGGC

Downstream 100 bases:

>100_bases
GGCATGAGGCATTTACAAGACCAAACCGTGTTGATCCTGGGCCTGGGTGCGTCCGGCCTGGCCATGGCGCGCTGGTGGGT
CCGCCATGGGGCATCGGTGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MPPSRRFGRRHFMLLSLAQWLQSISPEFGSFRVFQYLTFRAVMAALTALLIGLLAGPFVIRRLISLKIGQPIREYAMQTH
LSKSGTPTMGGVLILMSIGISTLLWFDLSNRFVWIVLLVTLGFGAIGWADDWRKVVLKDPEGMRSREKYLWQSLIGLVAA
LYLVFSISESSNLRVLELFFSWVQSGFDVDLPPKAGLLVPFVKEISYPLGVFGFVILTYLVIVGSSNAVNLTDGLDGLAI
MPVVMVGSALGVFAYVTGSAVYSKYLFFPHIPGSGELLIFCSAMAGAGLAFLWFNTHPAQVFMGDVGALALGAALGTIAV
IVRQEIVLAIMGGIFVVEALSVMMQVIWFKYTKKRYGEGRRLFKMAPLHHHFEKSGWKETQVVVRFWIITMLLCLVGLST
LKLR

Sequences:

>Translated_404_residues
MPPSRRFGRRHFMLLSLAQWLQSISPEFGSFRVFQYLTFRAVMAALTALLIGLLAGPFVIRRLISLKIGQPIREYAMQTH
LSKSGTPTMGGVLILMSIGISTLLWFDLSNRFVWIVLLVTLGFGAIGWADDWRKVVLKDPEGMRSREKYLWQSLIGLVAA
LYLVFSISESSNLRVLELFFSWVQSGFDVDLPPKAGLLVPFVKEISYPLGVFGFVILTYLVIVGSSNAVNLTDGLDGLAI
MPVVMVGSALGVFAYVTGSAVYSKYLFFPHIPGSGELLIFCSAMAGAGLAFLWFNTHPAQVFMGDVGALALGAALGTIAV
IVRQEIVLAIMGGIFVVEALSVMMQVIWFKYTKKRYGEGRRLFKMAPLHHHFEKSGWKETQVVVRFWIITMLLCLVGLST
LKLR
>Mature_403_residues
PPSRRFGRRHFMLLSLAQWLQSISPEFGSFRVFQYLTFRAVMAALTALLIGLLAGPFVIRRLISLKIGQPIREYAMQTHL
SKSGTPTMGGVLILMSIGISTLLWFDLSNRFVWIVLLVTLGFGAIGWADDWRKVVLKDPEGMRSREKYLWQSLIGLVAAL
YLVFSISESSNLRVLELFFSWVQSGFDVDLPPKAGLLVPFVKEISYPLGVFGFVILTYLVIVGSSNAVNLTDGLDGLAIM
PVVMVGSALGVFAYVTGSAVYSKYLFFPHIPGSGELLIFCSAMAGAGLAFLWFNTHPAQVFMGDVGALALGAALGTIAVI
VRQEIVLAIMGGIFVVEALSVMMQVIWFKYTKKRYGEGRRLFKMAPLHHHFEKSGWKETQVVVRFWIITMLLCLVGLSTL
KLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=388, Percent_Identity=51.0309278350515, Blast_Score=352, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 44804; Mature: 44673

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSRRFGRRHFMLLSLAQWLQSISPEFGSFRVFQYLTFRAVMAALTALLIGLLAGPFVI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLISLKIGQPIREYAMQTHLSKSGTPTMGGVLILMSIGISTLLWFDLSNRFVWIVLLVT
HHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LGFGAIGWADDWRKVVLKDPEGMRSREKYLWQSLIGLVAALYLVFSISESSNLRVLELFF
HCCCCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SWVQSGFDVDLPPKAGLLVPFVKEISYPLGVFGFVILTYLVIVGSSNAVNLTDGLDGLAI
HHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHH
MPVVMVGSALGVFAYVTGSAVYSKYLFFPHIPGSGELLIFCSAMAGAGLAFLWFNTHPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHCCCEEEEEECCCCHH
VFMGDVGALALGAALGTIAVIVRQEIVLAIMGGIFVVEALSVMMQVIWFKYTKKRYGEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLFKMAPLHHHFEKSGWKETQVVVRFWIITMLLCLVGLSTLKLR
HHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
PPSRRFGRRHFMLLSLAQWLQSISPEFGSFRVFQYLTFRAVMAALTALLIGLLAGPFVI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLISLKIGQPIREYAMQTHLSKSGTPTMGGVLILMSIGISTLLWFDLSNRFVWIVLLVT
HHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LGFGAIGWADDWRKVVLKDPEGMRSREKYLWQSLIGLVAALYLVFSISESSNLRVLELFF
HCCCCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SWVQSGFDVDLPPKAGLLVPFVKEISYPLGVFGFVILTYLVIVGSSNAVNLTDGLDGLAI
HHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHH
MPVVMVGSALGVFAYVTGSAVYSKYLFFPHIPGSGELLIFCSAMAGAGLAFLWFNTHPAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHCCCEEEEEECCCCHH
VFMGDVGALALGAALGTIAVIVRQEIVLAIMGGIFVVEALSVMMQVIWFKYTKKRYGEGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLFKMAPLHHHFEKSGWKETQVVVRFWIITMLLCLVGLSTLKLR
HHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA