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The map label for this gene is mlaA [H]

Identifier: 91786698

GI number: 91786698

Start: 823515

End: 824315

Strand: Direct

Name: mlaA [H]

Synonym: Bpro_0796

Alternate gene names: 91786698

Gene position: 823515-824315 (Clockwise)

Preceding gene: 91786697

Following gene: 91786699

Centisome position: 15.84

GC content: 61.55

Gene sequence:

>801_bases
ATGACGACGCGAACGATATCAACGACACAAAACACGATGAAGCGGTCCCTGTGGTGGGCGGCTGCAGCCTTGGCGCTGGC
GCTGCTGCAGGGTTGCGCAACCGGACCGAATGCCAACCCGGCCGATCCACTGGAGCCGTTCAACCGGGCGATGTTCAACT
TCAACGACGGTGTCGACCGCGCCCTCGTCAAGCCGGTAGCGACAGCTTACCGGGACGTCACACCCGCGCCCATCCGCACC
GCCGTCAACAGTTTTTTTGGCAATATTTCCGATGTCTGGTCGATGGTCAACAATGTGCTGCAGGCCAAGCCTGTAGAGGC
CACCGACAGCCTTTTCCGCATCACGGTCAATACATTGTGGGGCCTGGGCGGTATTTTTGATGTGGCCAGCGACTTGGGGA
TTCCCAAGCACAGCGAGGATTTTGGCCAGACCCTGGGATATTGGGGTGTCGCCTCCGGTCCCTATGTGGTGCTGCCACTG
CTGGGGCCCTCCACCGTGCGCGATTCCGTGGGCTCGCTGGTGGATGTGCAGGGAGATCTGGTGAGCCGGACGAATGATGT
ATCGGTGCGCAACTCCATGATCGTGCTGCGCGCGGTGGATCTGCGGGCCAACCTGCTGGGCACGGGCGCCCTGCTGGACG
AGGCTGCGCTTGATAGATACAGTTTTGCTCGTGATGTCTATCTGCAGCGCCGTCGCAGCCTGATTCGCGGTGCGGCAGCC
GAGACAGAAGAGCGCTACGACCTGCCAGAGGCCCCGGCGGCGCAGTCATCCAATGCATCTGCTTCGGCGCCTGCCAATTA
G

Upstream 100 bases:

>100_bases
TGGTGCTTGAAAGTCTGATCAGCCAGTTTTTGTATAGCAAAGCGGCGGACAGCAGTTCTGGATCAGGGGCTGCGCCGTCA
CCAGGGACGCCAGAAAAAAA

Downstream 100 bases:

>100_bases
AGGGAAAAAGAGAAAGAGCCTTTGTAAACAAAATTTACAAGACTGCTGTACAACTTCACCCTTAGCCCCGAACAAACCCG
GAAAATAGCCGTTGAATCAC

Product: VacJ-like protein lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTTRTISTTQNTMKRSLWWAAAALALALLQGCATGPNANPADPLEPFNRAMFNFNDGVDRALVKPVATAYRDVTPAPIRT
AVNSFFGNISDVWSMVNNVLQAKPVEATDSLFRITVNTLWGLGGIFDVASDLGIPKHSEDFGQTLGYWGVASGPYVVLPL
LGPSTVRDSVGSLVDVQGDLVSRTNDVSVRNSMIVLRAVDLRANLLGTGALLDEAALDRYSFARDVYLQRRRSLIRGAAA
ETEERYDLPEAPAAQSSNASASAPAN

Sequences:

>Translated_266_residues
MTTRTISTTQNTMKRSLWWAAAALALALLQGCATGPNANPADPLEPFNRAMFNFNDGVDRALVKPVATAYRDVTPAPIRT
AVNSFFGNISDVWSMVNNVLQAKPVEATDSLFRITVNTLWGLGGIFDVASDLGIPKHSEDFGQTLGYWGVASGPYVVLPL
LGPSTVRDSVGSLVDVQGDLVSRTNDVSVRNSMIVLRAVDLRANLLGTGALLDEAALDRYSFARDVYLQRRRSLIRGAAA
ETEERYDLPEAPAAQSSNASASAPAN
>Mature_265_residues
TTRTISTTQNTMKRSLWWAAAALALALLQGCATGPNANPADPLEPFNRAMFNFNDGVDRALVKPVATAYRDVTPAPIRTA
VNSFFGNISDVWSMVNNVLQAKPVEATDSLFRITVNTLWGLGGIFDVASDLGIPKHSEDFGQTLGYWGVASGPYVVLPLL
GPSTVRDSVGSLVDVQGDLVSRTNDVSVRNSMIVLRAVDLRANLLGTGALLDEAALDRYSFARDVYLQRRRSLIRGAAAE
TEERYDLPEAPAAQSSNASASAPAN

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=244, Percent_Identity=38.1147540983607, Blast_Score=138, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 28529; Mature: 28398

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRTISTTQNTMKRSLWWAAAALALALLQGCATGPNANPADPLEPFNRAMFNFNDGVDR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHH
ALVKPVATAYRDVTPAPIRTAVNSFFGNISDVWSMVNNVLQAKPVEATDSLFRITVNTLW
HHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GLGGIFDVASDLGIPKHSEDFGQTLGYWGVASGPYVVLPLLGPSTVRDSVGSLVDVQGDL
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHEEECCCHH
VSRTNDVSVRNSMIVLRAVDLRANLLGTGALLDEAALDRYSFARDVYLQRRRSLIRGAAA
HHCCCCCHHHHCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETEERYDLPEAPAAQSSNASASAPAN
CCHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTRTISTTQNTMKRSLWWAAAALALALLQGCATGPNANPADPLEPFNRAMFNFNDGVDR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHH
ALVKPVATAYRDVTPAPIRTAVNSFFGNISDVWSMVNNVLQAKPVEATDSLFRITVNTLW
HHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
GLGGIFDVASDLGIPKHSEDFGQTLGYWGVASGPYVVLPLLGPSTVRDSVGSLVDVQGDL
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHEEECCCHH
VSRTNDVSVRNSMIVLRAVDLRANLLGTGALLDEAALDRYSFARDVYLQRRRSLIRGAAA
HHCCCCCHHHHCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETEERYDLPEAPAAQSSNASASAPAN
CCHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]