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The map label for this gene is mlaE [H]

Identifier: 91786696

GI number: 91786696

Start: 822134

End: 822928

Strand: Direct

Name: mlaE [H]

Synonym: Bpro_0794

Alternate gene names: 91786696

Gene position: 822134-822928 (Clockwise)

Preceding gene: 91786695

Following gene: 91786697

Centisome position: 15.81

GC content: 61.76

Gene sequence:

>795_bases
ATGAGCCCTTACAGCCCCGTCCGCATGCTTTCCAATCTGGGTTTCGGCACGCGCAGCCAGCTGGCCGAGCTTGGCCATGC
CGCGCGCCTGATGTCGCGCCTGCTGGCGCTGACGGGTCCGGCGCTGGCCCGTTTTGGCCTGGTGCGTGACCAGATTTTCT
TTCTCGGCAATTATTCGCTGGCCATCATCACGGTATCCGGTCTTTTTGTGGGTTTTGTGCTCGGCCTGCAGGGCTACTAC
ACGCTGCAGCGTTATGGCTCCTCGGAGGCCCTGGGCTTGCTGGTGGCGCTTAGCCTGGTGCGAGAACTGGGCCCTGTGGT
CACGGCCTTGCTGTTTGCCGGCCGTGCCGGTACCTCGCTGACTGCAGAAATCGGCCTGATGAAAGCTGGTGAACAGCTAT
CGGCCATGGAAATGATGGCCGTTGATCCGGTGCGTCGCATCCTCGCGCCCCGGTTCTGGGGTGGGGTGATCGCCATGCCG
CTGCTGGCTGCGGTATTCAGTGCTGTCGGCATCATCGGGGGCTGGGTGGTCGGCGTGGTGATGATCGGTGTCGATGCGGG
TTCTTTCTGGAGCCAGATGCAGGCCGGCGTGGATGTCTGGCGCGACGTTGGCAACGGTGTGATCAAAAGTTTTGTATTTG
GTGTGACTGTCACTTTTGTGGCGCTGCACCAGGGGTTTGAAGCGCAACCTACGCCGGAAGGCGTGTCGCGCGCCACCACC
CGCACCGTGGTGGTGGCGTCGCTGGCTGTGCTTGGACTGGACTTCTTGTTGACCGCCTGGATGTTCAGCCTTTAA

Upstream 100 bases:

>100_bases
TCAACGCACAGAGCGAAGGTCCCGTGAAATTCCATTACCCCGGCCCGGACGTCGCCACCGATTTCGGACGGCAGGCTACA
GCACGCCGGAGGGCTCGCTC

Downstream 100 bases:

>100_bases
GGCGGGACGCGCACCTTATGAATCCAACCATGCGAAAATTCATCCCCTTTGCCGGCGCAGGTTTGGGTCATTGAAGGAAA
AAAATGCAACGTTCAAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSPYSPVRMLSNLGFGTRSQLAELGHAARLMSRLLALTGPALARFGLVRDQIFFLGNYSLAIITVSGLFVGFVLGLQGYY
TLQRYGSSEALGLLVALSLVRELGPVVTALLFAGRAGTSLTAEIGLMKAGEQLSAMEMMAVDPVRRILAPRFWGGVIAMP
LLAAVFSAVGIIGGWVVGVVMIGVDAGSFWSQMQAGVDVWRDVGNGVIKSFVFGVTVTFVALHQGFEAQPTPEGVSRATT
RTVVVASLAVLGLDFLLTAWMFSL

Sequences:

>Translated_264_residues
MSPYSPVRMLSNLGFGTRSQLAELGHAARLMSRLLALTGPALARFGLVRDQIFFLGNYSLAIITVSGLFVGFVLGLQGYY
TLQRYGSSEALGLLVALSLVRELGPVVTALLFAGRAGTSLTAEIGLMKAGEQLSAMEMMAVDPVRRILAPRFWGGVIAMP
LLAAVFSAVGIIGGWVVGVVMIGVDAGSFWSQMQAGVDVWRDVGNGVIKSFVFGVTVTFVALHQGFEAQPTPEGVSRATT
RTVVVASLAVLGLDFLLTAWMFSL
>Mature_263_residues
SPYSPVRMLSNLGFGTRSQLAELGHAARLMSRLLALTGPALARFGLVRDQIFFLGNYSLAIITVSGLFVGFVLGLQGYYT
LQRYGSSEALGLLVALSLVRELGPVVTALLFAGRAGTSLTAEIGLMKAGEQLSAMEMMAVDPVRRILAPRFWGGVIAMPL
LAAVFSAVGIIGGWVVGVVMIGVDAGSFWSQMQAGVDVWRDVGNGVIKSFVFGVTVTFVALHQGFEAQPTPEGVSRATTR
TVVVASLAVLGLDFLLTAWMFSL

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG0767

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaE permease family [H]

Homologues:

Organism=Escherichia coli, GI1789585, Length=217, Percent_Identity=64.5161290322581, Blast_Score=264, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003453 [H]

Pfam domain/function: PF02405 DUF140 [H]

EC number: NA

Molecular weight: Translated: 27977; Mature: 27846

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPYSPVRMLSNLGFGTRSQLAELGHAARLMSRLLALTGPALARFGLVRDQIFFLGNYSL
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCE
AIITVSGLFVGFVLGLQGYYTLQRYGSSEALGLLVALSLVRELGPVVTALLFAGRAGTSL
EEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TAEIGLMKAGEQLSAMEMMAVDPVRRILAPRFWGGVIAMPLLAAVFSAVGIIGGWVVGVV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIGVDAGSFWSQMQAGVDVWRDVGNGVIKSFVFGVTVTFVALHQGFEAQPTPEGVSRATT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RTVVVASLAVLGLDFLLTAWMFSL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]