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The map label for this gene is hipO [H]

Identifier: 91786651

GI number: 91786651

Start: 766073

End: 767356

Strand: Direct

Name: hipO [H]

Synonym: Bpro_0749

Alternate gene names: 91786651

Gene position: 766073-767356 (Clockwise)

Preceding gene: 91786650

Following gene: 91786654

Centisome position: 14.73

GC content: 65.73

Gene sequence:

>1284_bases
GTGCAAGCCGGCCGACCGGGCCAGCTGCGCGCCAGTGGCCGGGCCTTTGCGCAAATCTCGCAGTTCCATCCGGAGTTGAC
GGCTTTTCGCCGGGACCTGCACGCCCACCCCGAACTGGGCTTTGAAGAGGTCTATACCTCAAGCCGCGTGGCGCATGCGC
TCAAACTATGCGGCGTGGATGAAGTGCACACCGGCATTGCGAAAACCGGCGTGGTTGCCGTCATCAAGGGCCAGCAAACC
GGCACCGCGTTCACGTCCGGTGCCCGGCCCATGGTGGGCTTGCGCGCCGACATGGATGCCCTGCCCATGACGGAGCACAA
CGAGTTTGGCTGGAAGTCCTCCAAAACCGGGTTGATGCATGGCTGTGGCCACGATGGCCACACCACCATGCTGGTAGGCG
CCGCCCGCTACCTGGCCGAGACACGCCATTTTGCCGGCGATGCGGTGCTTGTTTTTCAACCGGCGGAAGAGGGGCGCGGC
GGGGCAGAGGCCATGATCCAGGCCGGGCTGTTCGAGCGTTTTCCGGTGCAATCGATTTACGCCATGCACAACTGGCCCTC
CATGCGTCCCGGCACCATTGGCATCAATCCCGGGCCCATGATGGCTGCGGCCGACCGCGTCACCATCGAGATTGCCGGCA
AGGGCGGCCATGGCGCACATGCCTACCTCACGGTCGATCCGGTGCTGGTGGCCGCTCACATCATCACGGCGGTGCAGAGC
ATCGTCTCGCGCAACGTGAAGGCCATGGACAGCGCCGTGATCAGCCTGTGCGCCATGCACGCGGGGGACCCCGGGGCGAT
GAGCGTGGTGGCCGGCAGTGCCACGCTGGTGGGCACGGTGCGCACCTTCAGGCCCGACGTGCAGAACCTGGTGGAGCGGC
GCCTGCAGGATTTGTGCACGTCGGTGGCGCAGGGCTTTGGCGCCACGGCGACGGTGACCTACGAACGCATTTATCCGGCC
ACCATCAACTCGCCCGCCGAGTACACATTGGCGACGGCCGTGGCCGACCAGCTTGTCGGCCCGGAAAACGTGGTGCGCGA
TCTGGAGCCCAGCATGGGCTCGGAAGATTTCTCTTTCATGCTCCAGGTCAAGCCGGGCGCCTACCTGCGCCTGGGCCAGG
GTGAGCAGCTCCCGGATGGCAAGGGCGCCAGCATTGGCGGCGTGGGCAGCCGCTTTCTGCACAACAGCTGCTACGACTTC
AACGACAGCGTGCTGCCGCTGGGCTCGGCCCTGTTTGCGGGGATTGTGGAACGCTCCCTGCCGCTCAAGCCTCAGGCGGT
GTGA

Upstream 100 bases:

>100_bases
TTTGCTGAACCGAGGATCTATCTCCATGCGCGCTCCGGCCACCATTGATGCCAGCTCTCTCGCCATCGCATCTGACGCTT
CTGCCTCCGCCGTCACTTCA

Downstream 100 bases:

>100_bases
CTCCTTCTTCCTCCAGGAGAGTGCAGGCGACATGACTGCCTCGCCCTCTGGGAGAGGGCAGGGGTGAGGGCTTGCGGCGG
CTGAAAAAATCCGGCCCTTT

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQAGRPGQLRASGRAFAQISQFHPELTAFRRDLHAHPELGFEEVYTSSRVAHALKLCGVDEVHTGIAKTGVVAVIKGQQT
GTAFTSGARPMVGLRADMDALPMTEHNEFGWKSSKTGLMHGCGHDGHTTMLVGAARYLAETRHFAGDAVLVFQPAEEGRG
GAEAMIQAGLFERFPVQSIYAMHNWPSMRPGTIGINPGPMMAAADRVTIEIAGKGGHGAHAYLTVDPVLVAAHIITAVQS
IVSRNVKAMDSAVISLCAMHAGDPGAMSVVAGSATLVGTVRTFRPDVQNLVERRLQDLCTSVAQGFGATATVTYERIYPA
TINSPAEYTLATAVADQLVGPENVVRDLEPSMGSEDFSFMLQVKPGAYLRLGQGEQLPDGKGASIGGVGSRFLHNSCYDF
NDSVLPLGSALFAGIVERSLPLKPQAV

Sequences:

>Translated_427_residues
MQAGRPGQLRASGRAFAQISQFHPELTAFRRDLHAHPELGFEEVYTSSRVAHALKLCGVDEVHTGIAKTGVVAVIKGQQT
GTAFTSGARPMVGLRADMDALPMTEHNEFGWKSSKTGLMHGCGHDGHTTMLVGAARYLAETRHFAGDAVLVFQPAEEGRG
GAEAMIQAGLFERFPVQSIYAMHNWPSMRPGTIGINPGPMMAAADRVTIEIAGKGGHGAHAYLTVDPVLVAAHIITAVQS
IVSRNVKAMDSAVISLCAMHAGDPGAMSVVAGSATLVGTVRTFRPDVQNLVERRLQDLCTSVAQGFGATATVTYERIYPA
TINSPAEYTLATAVADQLVGPENVVRDLEPSMGSEDFSFMLQVKPGAYLRLGQGEQLPDGKGASIGGVGSRFLHNSCYDF
NDSVLPLGSALFAGIVERSLPLKPQAV
>Mature_427_residues
MQAGRPGQLRASGRAFAQISQFHPELTAFRRDLHAHPELGFEEVYTSSRVAHALKLCGVDEVHTGIAKTGVVAVIKGQQT
GTAFTSGARPMVGLRADMDALPMTEHNEFGWKSSKTGLMHGCGHDGHTTMLVGAARYLAETRHFAGDAVLVFQPAEEGRG
GAEAMIQAGLFERFPVQSIYAMHNWPSMRPGTIGINPGPMMAAADRVTIEIAGKGGHGAHAYLTVDPVLVAAHIITAVQS
IVSRNVKAMDSAVISLCAMHAGDPGAMSVVAGSATLVGTVRTFRPDVQNLVERRLQDLCTSVAQGFGATATVTYERIYPA
TINSPAEYTLATAVADQLVGPENVVRDLEPSMGSEDFSFMLQVKPGAYLRLGQGEQLPDGKGASIGGVGSRFLHNSCYDF
NDSVLPLGSALFAGIVERSLPLKPQAV

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=431, Percent_Identity=26.9141531322506, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 45218; Mature: 45218

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAGRPGQLRASGRAFAQISQFHPELTAFRRDLHAHPELGFEEVYTSSRVAHALKLCGVD
CCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCH
EVHTGIAKTGVVAVIKGQQTGTAFTSGARPMVGLRADMDALPMTEHNEFGWKSSKTGLMH
HHHHHHHHCCEEEEEECCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEE
GCGHDGHTTMLVGAARYLAETRHFAGDAVLVFQPAEEGRGGAEAMIQAGLFERFPVQSIY
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHH
AMHNWPSMRPGTIGINPGPMMAAADRVTIEIAGKGGHGAHAYLTVDPVLVAAHIITAVQS
HHHCCCCCCCCEECCCCCCCEEECCEEEEEEECCCCCCEEEEEEECHHHHHHHHHHHHHH
IVSRNVKAMDSAVISLCAMHAGDPGAMSVVAGSATLVGTVRTFRPDVQNLVERRLQDLCT
HHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEHHHHHCHHHHHHHHHHHHHHHH
SVAQGFGATATVTYERIYPATINSPAEYTLATAVADQLVGPENVVRDLEPSMGSEDFSFM
HHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEE
LQVKPGAYLRLGQGEQLPDGKGASIGGVGSRFLHNSCYDFNDSVLPLGSALFAGIVERSL
EEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
PLKPQAV
CCCCCCC
>Mature Secondary Structure
MQAGRPGQLRASGRAFAQISQFHPELTAFRRDLHAHPELGFEEVYTSSRVAHALKLCGVD
CCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCH
EVHTGIAKTGVVAVIKGQQTGTAFTSGARPMVGLRADMDALPMTEHNEFGWKSSKTGLMH
HHHHHHHHCCEEEEEECCCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEE
GCGHDGHTTMLVGAARYLAETRHFAGDAVLVFQPAEEGRGGAEAMIQAGLFERFPVQSIY
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHH
AMHNWPSMRPGTIGINPGPMMAAADRVTIEIAGKGGHGAHAYLTVDPVLVAAHIITAVQS
HHHCCCCCCCCEECCCCCCCEEECCEEEEEEECCCCCCEEEEEEECHHHHHHHHHHHHHH
IVSRNVKAMDSAVISLCAMHAGDPGAMSVVAGSATLVGTVRTFRPDVQNLVERRLQDLCT
HHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEHHHHHCHHHHHHHHHHHHHHHH
SVAQGFGATATVTYERIYPATINSPAEYTLATAVADQLVGPENVVRDLEPSMGSEDFSFM
HHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEE
LQVKPGAYLRLGQGEQLPDGKGASIGGVGSRFLHNSCYDFNDSVLPLGSALFAGIVERSL
EEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
PLKPQAV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]