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The map label for this gene is queC

Identifier: 91786636

GI number: 91786636

Start: 749349

End: 750056

Strand: Direct

Name: queC

Synonym: Bpro_0734

Alternate gene names: 91786636

Gene position: 749349-750056 (Clockwise)

Preceding gene: 91786635

Following gene: 91786646

Centisome position: 14.41

GC content: 64.41

Gene sequence:

>708_bases
ATGCATACCTCCGCACTCGTGCTGTTTTCCGGGGGGCAGGATTCGACCACCTGCCTGGCCCAGGCGCTCTCCAAATACGA
GCGCGTGGAAACCGTCGCCTTTGACTACGGCCAGCGTCACAAGGTCGAGCTTGACGCACGCCTGAATGTGCTGCGCGAAA
TCAAAAGCCGGTTTCCGCACTGGGCGCCCAAGCTGGGCGAAGACCATCTGCTCGACCTGGCCGTGCTGGGGCAGGTGAGC
GACACCTCGCTGACGCGCGACGTGGCCTTCAAGATGGAAAACTCGGGCCTGCCCAACACCTTTGTGCCGGGGCGCAACCT
GCTGTTTCTCACGCTGGCGGCCGCGCTGGCTTACCGGCGCGATTTGCAGGTGCTGGTGACGGGTGTTTGCGAAACCGATT
TTTCAGGCTACCCCGACTGCCGCGACGACACCATCAAGGCCATGCAGCTGGCGCTCTCGCTGGGCATGGACAAGCGCTTT
TTGATCGAGACACCGCTGATGTGGATCGACAAGGCCGACACCTGGCGCCTGGCCCATGCGCTGGGCGGCCAGGCGCTGGT
CGATCTGATCATCGAGCACACCCACACCTGCTACCTGGGTGACCGCACGCACCGGCAGGCCTGGGGTTATGGCTGTGGGG
CATGCCCGGCCTGCGAGCTGCGGGCGCGCGGCTATGAGCGCTATGCGGCGGCCTTGTCGAAGCCGTAA

Upstream 100 bases:

>100_bases
CACCACGTCGGACAAGGCCGCGCCCTGGACTTTTGGCGTCACGGCGCTGATGCAGAGCCTGGCGGGCCGCGGCCTGCTGT
AGAAAGGGGTGGAGCCGGCC

Downstream 100 bases:

>100_bases
TCGCGTTCAACCTTTGCAATGCGCGTTTTGTACTGGGTGTACCAGTCGCTGCGACCGGTTTGTTGTGCAATCAGGTGCTC
GGCATGGGCCTTCCAGGCTT

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MHTSALVLFSGGQDSTTCLAQALSKYERVETVAFDYGQRHKVELDARLNVLREIKSRFPHWAPKLGEDHLLDLAVLGQVS
DTSLTRDVAFKMENSGLPNTFVPGRNLLFLTLAAALAYRRDLQVLVTGVCETDFSGYPDCRDDTIKAMQLALSLGMDKRF
LIETPLMWIDKADTWRLAHALGGQALVDLIIEHTHTCYLGDRTHRQAWGYGCGACPACELRARGYERYAAALSKP

Sequences:

>Translated_235_residues
MHTSALVLFSGGQDSTTCLAQALSKYERVETVAFDYGQRHKVELDARLNVLREIKSRFPHWAPKLGEDHLLDLAVLGQVS
DTSLTRDVAFKMENSGLPNTFVPGRNLLFLTLAAALAYRRDLQVLVTGVCETDFSGYPDCRDDTIKAMQLALSLGMDKRF
LIETPLMWIDKADTWRLAHALGGQALVDLIIEHTHTCYLGDRTHRQAWGYGCGACPACELRARGYERYAAALSKP
>Mature_235_residues
MHTSALVLFSGGQDSTTCLAQALSKYERVETVAFDYGQRHKVELDARLNVLREIKSRFPHWAPKLGEDHLLDLAVLGQVS
DTSLTRDVAFKMENSGLPNTFVPGRNLLFLTLAAALAYRRDLQVLVTGVCETDFSGYPDCRDDTIKAMQLALSLGMDKRF
LIETPLMWIDKADTWRLAHALGGQALVDLIIEHTHTCYLGDRTHRQAWGYGCGACPACELRARGYERYAAALSKP

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=230, Percent_Identity=52.1739130434783, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_POLSJ (Q12FK2)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547588.1
- ProteinModelPortal:   Q12FK2
- SMR:   Q12FK2
- STRING:   Q12FK2
- GeneID:   4011291
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_0734
- NMPDR:   fig|296591.1.peg.2137
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   Q12FK2
- ProtClustDB:   CLSK864419
- BioCyc:   PSP296591:BPRO_0734-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26189; Mature: 26189

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSALVLFSGGQDSTTCLAQALSKYERVETVAFDYGQRHKVELDARLNVLREIKSRFPH
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCC
WAPKLGEDHLLDLAVLGQVSDTSLTRDVAFKMENSGLPNTFVPGRNLLFLTLAAALAYRR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
DLQVLVTGVCETDFSGYPDCRDDTIKAMQLALSLGMDKRFLIETPLMWIDKADTWRLAHA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHEECCCCHHHHHHH
LGGQALVDLIIEHTHTCYLGDRTHRQAWGYGCGACPACELRARGYERYAAALSKP
HCHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MHTSALVLFSGGQDSTTCLAQALSKYERVETVAFDYGQRHKVELDARLNVLREIKSRFPH
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCC
WAPKLGEDHLLDLAVLGQVSDTSLTRDVAFKMENSGLPNTFVPGRNLLFLTLAAALAYRR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
DLQVLVTGVCETDFSGYPDCRDDTIKAMQLALSLGMDKRFLIETPLMWIDKADTWRLAHA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHEECCCCHHHHHHH
LGGQALVDLIIEHTHTCYLGDRTHRQAWGYGCGACPACELRARGYERYAAALSKP
HCHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA