| Definition | Francisella tularensis subsp. holarctica LVS chromosome, complete genome. |
|---|---|
| Accession | NC_007880 |
| Length | 1,895,994 |
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The map label for this gene is ftsH [H]
Identifier: 89256757
GI number: 89256757
Start: 1392490
End: 1394436
Strand: Reverse
Name: ftsH [H]
Synonym: FTL_1468
Alternate gene names: 89256757
Gene position: 1394436-1392490 (Counterclockwise)
Preceding gene: 89256762
Following gene: 89256753
Centisome position: 73.55
GC content: 37.7
Gene sequence:
>1947_bases ATGGCACAAAATAATGATAATAAAAATAATATGATTAAAAATATTATTTTTTGGATTTTAATCATTGGTGGGATGCTACT GCTTTTCAATGGTATTAATGATACAAATGGGTCATCTAAAAATATAAATTATTCGACATTTATTTCTAAGTTAAAAGATA ATCAAATTAGCGTTATAGATGTCGATGGTAGAACTATCACGGGTAAAACCAATGAAGGTGAGAGTTTTGTAACATACGCA CCATTACTAGATGGTAGTTTAGTTAATAAATTAGAAGATAGTAATGCTATAGTCAAAGCAAAAGCTCCAGAAAAGCCTAA TATATTCTTGGCATTTTTGCTTAACTGGTTACCAATGCTACTAATTTTTGGCTTTTTCATTTATATGATGGTAAAAGCTG GTGGCGGTAGCAAAGGCGGACCTTTCTCTGTTGGTAAGAGTAAAGCAAAATTACTAGGTGAAGATGAGATTAAAGTAACT TTAGATGATGTTGCTGGTGTTGATGAAGCCAAAGAAGAAGTTGCTGAAATAGTTGATTTCTTACGTGAGCCAAAAAAATA TGAGAAGATTGGCGGTAAGATTCCTAAAGGCGTATTGATGGTAGGACCTCCTGGTACCGGTAAGACATTATTAGCTAGAG CTATTGCTGGTGAAGCAAAGGTTCCATTTTTCTCAATTTCAGGCTCTGATTTTGTTGAGATGTTTGTTGGGGTTGGTGCA TCGCGTGTTCGTGATATGTTCGAACAAGCTAAAAAGAAAGCTCCTTGCTTAGTTTTTATCGATGAAATAGATGCAGTAGG CCGTCATCGTGGCTCAGGTATGGGTGGTGGTAATGATGAGAGAGAACAAACTCTTAACCAAATGCTTGTTGAGATGGATG GTTTTGCCGATAATGAGGGTGTAATAGTAATAGCAGCTACTAATAGACCAGATGTTTTAGACAGAGCATTACTAAGACCT GGTAGATTTGATAGACAAGTTACAGTTGGTTTACCAACAGTAAAAGGACGTGAAGCGATACTAAAAGTGCATATGAAAAA AGTTGCTCTAGGTGAAGATGTCCGTGCTGATTGGATAGCAAGAGGCACACCAGGATTTTCTGGTGCAGAACTTGCAAACC TTGTTAATGAAGCGGCTTTATTTGCTGCAAGAGAATCTAAAGATAAAGTTTCAATGGCTGATTTTGAAAAAGCCAAAGAT AAAATCTTAATGGGTTCTGAAAGAAGAAGTATGGCAATGACTGAAAAAGAGAAAAGGCTTACGGCTTATCATGAAGCGGG TCATGCTATTATTGGTCGTTTGATGCCAGAGCATGATCCAGTTTATAAGGTAAGTATCATACCTAGAGGTAGAGCACTTG GTGTAACAATGTATATGCCAGAAGGTGATACTGTTAGCCAAAGCAGACTAGTGTTGCGTGGGCGCTTATGTAGTATTTTT GGTGGTAGAATAGCTGAGGAGCTTATTTTTGGTTATGATCATGTAACTACTGGAGCTTCTAATGATATTCAAGTGGCTAC TGATATAGCGCGCAATTATGTTGCTCGTTGGGGCTTATCTGATGCTATGGGAACTATCCTGTATGACGTTGAAGATGAAG GACCTTTTGGCGGTAGTGGTGGCAAGTCGGTAAAACTTTCAGACTCTACTATCAGAGAAGTAGATACTGAAGTGCGTAAA CTAATAGCTACAAGTTATGCTAAGGCTAAGCAATTGTTGGAAAAGAATATCGATATCCTTCATGCTATGGCTGATGCACT AATGAAATATGAGACTATAGATGCACTACAAGTTGATGATCTAATGGCTAGACGTCCAGTGCGTGAGCCAGGTGAATATG GTGATAGCTATAAACCAAAGGATACGGGTAAGGTTATAGCACCAGTAGTGCCTAATGAAGATGAGTTAGAAATAGCTGAT GATTCTAGCCTTAAAGAAGATCTTTAA
Upstream 100 bases:
>100_bases ATTTAGCAAAACGACTAGCTAATAATGAATTTTTTTACTATAGTATATTAGTTAAAATTTAGTATTAAACTTCATAAGGA AGAAAGGATTAAATAAATAT
Downstream 100 bases:
>100_bases TTATTAATCTATAAGAAATTCTTATCTAACTATTATGCTCTATATGCTAAGAGCATTATATATATTATAAGTTAATTTTA TTTTATTGTTTTTCTAGTAC
Product: ATP-dependent metalloprotease
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 648; Mature: 647
Protein sequence:
>648_residues MAQNNDNKNNMIKNIIFWILIIGGMLLLFNGINDTNGSSKNINYSTFISKLKDNQISVIDVDGRTITGKTNEGESFVTYA PLLDGSLVNKLEDSNAIVKAKAPEKPNIFLAFLLNWLPMLLIFGFFIYMMVKAGGGSKGGPFSVGKSKAKLLGEDEIKVT LDDVAGVDEAKEEVAEIVDFLREPKKYEKIGGKIPKGVLMVGPPGTGKTLLARAIAGEAKVPFFSISGSDFVEMFVGVGA SRVRDMFEQAKKKAPCLVFIDEIDAVGRHRGSGMGGGNDEREQTLNQMLVEMDGFADNEGVIVIAATNRPDVLDRALLRP GRFDRQVTVGLPTVKGREAILKVHMKKVALGEDVRADWIARGTPGFSGAELANLVNEAALFAARESKDKVSMADFEKAKD KILMGSERRSMAMTEKEKRLTAYHEAGHAIIGRLMPEHDPVYKVSIIPRGRALGVTMYMPEGDTVSQSRLVLRGRLCSIF GGRIAEELIFGYDHVTTGASNDIQVATDIARNYVARWGLSDAMGTILYDVEDEGPFGGSGGKSVKLSDSTIREVDTEVRK LIATSYAKAKQLLEKNIDILHAMADALMKYETIDALQVDDLMARRPVREPGEYGDSYKPKDTGKVIAPVVPNEDELEIAD DSSLKEDL
Sequences:
>Translated_648_residues MAQNNDNKNNMIKNIIFWILIIGGMLLLFNGINDTNGSSKNINYSTFISKLKDNQISVIDVDGRTITGKTNEGESFVTYA PLLDGSLVNKLEDSNAIVKAKAPEKPNIFLAFLLNWLPMLLIFGFFIYMMVKAGGGSKGGPFSVGKSKAKLLGEDEIKVT LDDVAGVDEAKEEVAEIVDFLREPKKYEKIGGKIPKGVLMVGPPGTGKTLLARAIAGEAKVPFFSISGSDFVEMFVGVGA SRVRDMFEQAKKKAPCLVFIDEIDAVGRHRGSGMGGGNDEREQTLNQMLVEMDGFADNEGVIVIAATNRPDVLDRALLRP GRFDRQVTVGLPTVKGREAILKVHMKKVALGEDVRADWIARGTPGFSGAELANLVNEAALFAARESKDKVSMADFEKAKD KILMGSERRSMAMTEKEKRLTAYHEAGHAIIGRLMPEHDPVYKVSIIPRGRALGVTMYMPEGDTVSQSRLVLRGRLCSIF GGRIAEELIFGYDHVTTGASNDIQVATDIARNYVARWGLSDAMGTILYDVEDEGPFGGSGGKSVKLSDSTIREVDTEVRK LIATSYAKAKQLLEKNIDILHAMADALMKYETIDALQVDDLMARRPVREPGEYGDSYKPKDTGKVIAPVVPNEDELEIAD DSSLKEDL >Mature_647_residues AQNNDNKNNMIKNIIFWILIIGGMLLLFNGINDTNGSSKNINYSTFISKLKDNQISVIDVDGRTITGKTNEGESFVTYAP LLDGSLVNKLEDSNAIVKAKAPEKPNIFLAFLLNWLPMLLIFGFFIYMMVKAGGGSKGGPFSVGKSKAKLLGEDEIKVTL DDVAGVDEAKEEVAEIVDFLREPKKYEKIGGKIPKGVLMVGPPGTGKTLLARAIAGEAKVPFFSISGSDFVEMFVGVGAS RVRDMFEQAKKKAPCLVFIDEIDAVGRHRGSGMGGGNDEREQTLNQMLVEMDGFADNEGVIVIAATNRPDVLDRALLRPG RFDRQVTVGLPTVKGREAILKVHMKKVALGEDVRADWIARGTPGFSGAELANLVNEAALFAARESKDKVSMADFEKAKDK ILMGSERRSMAMTEKEKRLTAYHEAGHAIIGRLMPEHDPVYKVSIIPRGRALGVTMYMPEGDTVSQSRLVLRGRLCSIFG GRIAEELIFGYDHVTTGASNDIQVATDIARNYVARWGLSDAMGTILYDVEDEGPFGGSGGKSVKLSDSTIREVDTEVRKL IATSYAKAKQLLEKNIDILHAMADALMKYETIDALQVDDLMARRPVREPGEYGDSYKPKDTGKVIAPVVPNEDELEIADD SSLKEDL
Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]
COG id: COG0465
COG function: function code O; ATP-dependent Zn proteases
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]
Homologues:
Organism=Homo sapiens, GI300192933, Length=514, Percent_Identity=46.692607003891, Blast_Score=458, Evalue=1e-129, Organism=Homo sapiens, GI7657689, Length=442, Percent_Identity=51.5837104072398, Blast_Score=443, Evalue=1e-124, Organism=Homo sapiens, GI21327685, Length=442, Percent_Identity=51.5837104072398, Blast_Score=442, Evalue=1e-124, Organism=Homo sapiens, GI4507173, Length=452, Percent_Identity=43.3628318584071, Blast_Score=375, Evalue=1e-104, Organism=Homo sapiens, GI24497435, Length=255, Percent_Identity=40.7843137254902, Blast_Score=209, Evalue=5e-54, Organism=Homo sapiens, GI4506209, Length=251, Percent_Identity=41.0358565737052, Blast_Score=209, Evalue=6e-54, Organism=Homo sapiens, GI21361144, Length=234, Percent_Identity=43.1623931623932, Blast_Score=201, Evalue=3e-51, Organism=Homo sapiens, GI24430151, Length=245, Percent_Identity=41.2244897959184, Blast_Score=200, Evalue=4e-51, Organism=Homo sapiens, GI195539395, Length=250, Percent_Identity=40.4, Blast_Score=197, Evalue=3e-50, Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=42.0353982300885, Blast_Score=193, Evalue=4e-49, Organism=Homo sapiens, GI24430155, Length=270, Percent_Identity=39.6296296296296, Blast_Score=187, Evalue=2e-47, Organism=Homo sapiens, GI89064750, Length=270, Percent_Identity=39.6296296296296, Blast_Score=187, Evalue=2e-47, Organism=Homo sapiens, GI5729991, Length=270, Percent_Identity=39.6296296296296, Blast_Score=187, Evalue=2e-47, Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=37.8181818181818, Blast_Score=178, Evalue=2e-44, Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=37.8181818181818, Blast_Score=177, Evalue=2e-44, Organism=Homo sapiens, GI40806173, Length=137, Percent_Identity=57.6642335766423, Blast_Score=175, Evalue=1e-43, Organism=Homo sapiens, GI157671927, Length=228, Percent_Identity=38.5964912280702, Blast_Score=175, Evalue=1e-43, Organism=Homo sapiens, GI229577436, Length=248, Percent_Identity=39.1129032258064, Blast_Score=163, Evalue=5e-40, Organism=Homo sapiens, GI4505725, Length=225, Percent_Identity=37.3333333333333, Blast_Score=155, Evalue=1e-37, Organism=Homo sapiens, GI5901990, Length=268, Percent_Identity=36.5671641791045, Blast_Score=151, Evalue=2e-36, Organism=Homo sapiens, GI14149767, Length=279, Percent_Identity=36.2007168458781, Blast_Score=148, Evalue=1e-35, Organism=Homo sapiens, GI62177112, Length=279, Percent_Identity=36.2007168458781, Blast_Score=148, Evalue=1e-35, Organism=Homo sapiens, GI24497618, Length=273, Percent_Identity=34.7985347985348, Blast_Score=146, Evalue=6e-35, Organism=Homo sapiens, GI153792536, Length=284, Percent_Identity=35.2112676056338, Blast_Score=145, Evalue=2e-34, Organism=Homo sapiens, GI194018488, Length=225, Percent_Identity=39.1111111111111, Blast_Score=143, Evalue=4e-34, Organism=Homo sapiens, GI226371754, Length=235, Percent_Identity=36.1702127659575, Blast_Score=143, Evalue=5e-34, Organism=Homo sapiens, GI156564401, Length=236, Percent_Identity=38.5593220338983, Blast_Score=135, Evalue=1e-31, Organism=Homo sapiens, GI17865802, Length=249, Percent_Identity=36.5461847389558, Blast_Score=135, Evalue=2e-31, Organism=Homo sapiens, GI31742536, Length=289, Percent_Identity=31.4878892733564, Blast_Score=132, Evalue=1e-30, Organism=Homo sapiens, GI112789543, Length=289, Percent_Identity=31.4878892733564, Blast_Score=132, Evalue=1e-30, Organism=Homo sapiens, GI310125280, Length=236, Percent_Identity=37.7118644067797, Blast_Score=132, Evalue=1e-30, Organism=Homo sapiens, GI310125282, Length=236, Percent_Identity=37.7118644067797, Blast_Score=131, Evalue=2e-30, Organism=Homo sapiens, GI7019569, Length=233, Percent_Identity=33.9055793991416, Blast_Score=130, Evalue=4e-30, Organism=Homo sapiens, GI11875211, Length=263, Percent_Identity=36.8821292775665, Blast_Score=130, Evalue=6e-30, Organism=Homo sapiens, GI40806170, Length=263, Percent_Identity=36.8821292775665, Blast_Score=129, Evalue=8e-30, Organism=Homo sapiens, GI31377644, Length=250, Percent_Identity=34.8, Blast_Score=125, Evalue=1e-28, Organism=Homo sapiens, GI64084766, Length=277, Percent_Identity=27.4368231046931, Blast_Score=91, Evalue=4e-18, Organism=Homo sapiens, GI116292174, Length=249, Percent_Identity=30.1204819277108, Blast_Score=81, Evalue=3e-15, Organism=Escherichia coli, GI1789568, Length=633, Percent_Identity=60.9794628751975, Blast_Score=791, Evalue=0.0, Organism=Caenorhabditis elegans, GI71994521, Length=509, Percent_Identity=45.5795677799607, Blast_Score=420, Evalue=1e-117, Organism=Caenorhabditis elegans, GI17554264, Length=448, Percent_Identity=46.6517857142857, Blast_Score=399, Evalue=1e-111, Organism=Caenorhabditis elegans, GI115534323, Length=492, Percent_Identity=41.869918699187, Blast_Score=358, Evalue=4e-99, Organism=Caenorhabditis elegans, GI25144278, Length=255, Percent_Identity=42.3529411764706, Blast_Score=219, Evalue=3e-57, Organism=Caenorhabditis elegans, GI25144281, Length=255, Percent_Identity=42.3529411764706, Blast_Score=219, Evalue=3e-57, Organism=Caenorhabditis elegans, GI17563248, Length=271, Percent_Identity=40.9594095940959, Blast_Score=215, Evalue=5e-56, Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=41.5686274509804, Blast_Score=214, Evalue=1e-55, Organism=Caenorhabditis elegans, GI17508053, Length=253, Percent_Identity=43.4782608695652, Blast_Score=202, Evalue=6e-52, Organism=Caenorhabditis elegans, GI17532375, Length=287, Percent_Identity=36.9337979094077, Blast_Score=201, Evalue=7e-52, Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=41.3385826771654, Blast_Score=199, Evalue=3e-51, Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=41.3385826771654, Blast_Score=199, Evalue=4e-51, Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=40.8163265306122, Blast_Score=197, Evalue=2e-50, Organism=Caenorhabditis elegans, GI17508701, Length=234, Percent_Identity=41.4529914529915, Blast_Score=192, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17531535, Length=253, Percent_Identity=41.1067193675889, Blast_Score=188, Evalue=6e-48, Organism=Caenorhabditis elegans, GI17505546, Length=303, Percent_Identity=37.6237623762376, Blast_Score=187, Evalue=2e-47, Organism=Caenorhabditis elegans, GI17554784, Length=329, Percent_Identity=34.3465045592705, Blast_Score=177, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17537217, Length=258, Percent_Identity=37.2093023255814, Blast_Score=162, Evalue=7e-40, Organism=Caenorhabditis elegans, GI25153574, Length=228, Percent_Identity=36.8421052631579, Blast_Score=154, Evalue=2e-37, Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=46.0606060606061, Blast_Score=152, Evalue=4e-37, Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=46.0606060606061, Blast_Score=152, Evalue=4e-37, Organism=Caenorhabditis elegans, GI193209502, Length=227, Percent_Identity=36.5638766519824, Blast_Score=150, Evalue=3e-36, Organism=Caenorhabditis elegans, GI133931034, Length=267, Percent_Identity=36.7041198501873, Blast_Score=147, Evalue=2e-35, Organism=Caenorhabditis elegans, GI193206116, Length=267, Percent_Identity=36.7041198501873, Blast_Score=147, Evalue=2e-35, Organism=Caenorhabditis elegans, GI193206114, Length=267, Percent_Identity=36.7041198501873, Blast_Score=147, Evalue=2e-35, Organism=Caenorhabditis elegans, GI25146157, Length=261, Percent_Identity=37.5478927203065, Blast_Score=142, Evalue=7e-34, Organism=Caenorhabditis elegans, GI17562804, Length=235, Percent_Identity=35.7446808510638, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=38.6792452830189, Blast_Score=133, Evalue=3e-31, Organism=Caenorhabditis elegans, GI133901662, Length=212, Percent_Identity=38.6792452830189, Blast_Score=133, Evalue=3e-31, Organism=Caenorhabditis elegans, GI17508421, Length=234, Percent_Identity=36.7521367521368, Blast_Score=124, Evalue=2e-28, Organism=Caenorhabditis elegans, GI32563584, Length=234, Percent_Identity=36.7521367521368, Blast_Score=124, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17560432, Length=238, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=8e-28, Organism=Caenorhabditis elegans, GI86561515, Length=234, Percent_Identity=32.0512820512821, Blast_Score=120, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17541226, Length=274, Percent_Identity=29.5620437956204, Blast_Score=112, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17541224, Length=274, Percent_Identity=29.5620437956204, Blast_Score=112, Evalue=9e-25, Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6323736, Length=518, Percent_Identity=45.945945945946, Blast_Score=452, Evalue=1e-128, Organism=Saccharomyces cerevisiae, GI6325281, Length=498, Percent_Identity=47.7911646586345, Blast_Score=451, Evalue=1e-127, Organism=Saccharomyces cerevisiae, GI6320854, Length=545, Percent_Identity=44.2201834862385, Blast_Score=444, Evalue=1e-125, Organism=Saccharomyces cerevisiae, GI6322704, Length=271, Percent_Identity=39.8523985239852, Blast_Score=211, Evalue=4e-55, Organism=Saccharomyces cerevisiae, GI6320077, Length=260, Percent_Identity=41.5384615384615, Blast_Score=204, Evalue=3e-53, Organism=Saccharomyces cerevisiae, GI6321390, Length=257, Percent_Identity=37.7431906614786, Blast_Score=203, Evalue=6e-53, Organism=Saccharomyces cerevisiae, GI6324691, Length=237, Percent_Identity=43.0379746835443, Blast_Score=200, Evalue=7e-52, Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=40.2439024390244, Blast_Score=193, Evalue=7e-50, Organism=Saccharomyces cerevisiae, GI6320197, Length=242, Percent_Identity=39.6694214876033, Blast_Score=190, Evalue=7e-49, Organism=Saccharomyces cerevisiae, GI6320602, Length=255, Percent_Identity=39.2156862745098, Blast_Score=178, Evalue=2e-45, Organism=Saccharomyces cerevisiae, GI6324000, Length=242, Percent_Identity=41.3223140495868, Blast_Score=175, Evalue=2e-44, Organism=Saccharomyces cerevisiae, GI6323429, Length=253, Percent_Identity=40.3162055335968, Blast_Score=170, Evalue=6e-43, Organism=Saccharomyces cerevisiae, GI6322994, Length=231, Percent_Identity=38.0952380952381, Blast_Score=165, Evalue=2e-41, Organism=Saccharomyces cerevisiae, GI6321709, Length=282, Percent_Identity=37.5886524822695, Blast_Score=161, Evalue=3e-40, Organism=Saccharomyces cerevisiae, GI6322651, Length=238, Percent_Identity=36.9747899159664, Blast_Score=158, Evalue=2e-39, Organism=Saccharomyces cerevisiae, GI6321465, Length=241, Percent_Identity=38.5892116182573, Blast_Score=139, Evalue=2e-33, Organism=Saccharomyces cerevisiae, GI6325431, Length=292, Percent_Identity=32.8767123287671, Blast_Score=135, Evalue=1e-32, Organism=Saccharomyces cerevisiae, GI6319554, Length=220, Percent_Identity=37.2727272727273, Blast_Score=133, Evalue=8e-32, Organism=Saccharomyces cerevisiae, GI6325183, Length=265, Percent_Identity=34.7169811320755, Blast_Score=130, Evalue=7e-31, Organism=Saccharomyces cerevisiae, GI6320887, Length=263, Percent_Identity=33.8403041825095, Blast_Score=124, Evalue=5e-29, Organism=Saccharomyces cerevisiae, GI6320583, Length=157, Percent_Identity=29.2993630573248, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI28574878, Length=516, Percent_Identity=46.7054263565892, Blast_Score=459, Evalue=1e-129, Organism=Drosophila melanogaster, GI24665814, Length=516, Percent_Identity=46.7054263565892, Blast_Score=459, Evalue=1e-129, Organism=Drosophila melanogaster, GI24658770, Length=490, Percent_Identity=46.3265306122449, Blast_Score=438, Evalue=1e-123, Organism=Drosophila melanogaster, GI24639391, Length=456, Percent_Identity=46.0526315789474, Blast_Score=405, Evalue=1e-113, Organism=Drosophila melanogaster, GI17137738, Length=251, Percent_Identity=43.0278884462151, Blast_Score=213, Evalue=2e-55, Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=57.5757575757576, Blast_Score=212, Evalue=8e-55, Organism=Drosophila melanogaster, GI24651451, Length=255, Percent_Identity=40.7843137254902, Blast_Score=208, Evalue=9e-54, Organism=Drosophila melanogaster, GI19920408, Length=255, Percent_Identity=40, Blast_Score=206, Evalue=4e-53, Organism=Drosophila melanogaster, GI161076488, Length=264, Percent_Identity=38.6363636363636, Blast_Score=205, Evalue=9e-53, Organism=Drosophila melanogaster, GI17137560, Length=264, Percent_Identity=38.6363636363636, Blast_Score=205, Evalue=1e-52, Organism=Drosophila melanogaster, GI161076486, Length=264, Percent_Identity=38.6363636363636, Blast_Score=204, Evalue=1e-52, Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=41.6326530612245, Blast_Score=198, Evalue=8e-51, Organism=Drosophila melanogaster, GI17738151, Length=234, Percent_Identity=41.8803418803419, Blast_Score=196, Evalue=5e-50, Organism=Drosophila melanogaster, GI281365776, Length=232, Percent_Identity=42.6724137931034, Blast_Score=195, Evalue=6e-50, Organism=Drosophila melanogaster, GI24660075, Length=232, Percent_Identity=42.6724137931034, Blast_Score=195, Evalue=7e-50, Organism=Drosophila melanogaster, GI45552965, Length=232, Percent_Identity=42.6724137931034, Blast_Score=195, Evalue=1e-49, Organism=Drosophila melanogaster, GI24640100, Length=250, Percent_Identity=40.8, Blast_Score=194, Evalue=2e-49, Organism=Drosophila melanogaster, GI19921202, Length=245, Percent_Identity=40.4081632653061, Blast_Score=189, Evalue=4e-48, Organism=Drosophila melanogaster, GI281361487, Length=253, Percent_Identity=38.7351778656126, Blast_Score=185, Evalue=1e-46, Organism=Drosophila melanogaster, GI18860063, Length=258, Percent_Identity=39.1472868217054, Blast_Score=184, Evalue=1e-46, Organism=Drosophila melanogaster, GI24652279, Length=206, Percent_Identity=41.747572815534, Blast_Score=183, Evalue=3e-46, Organism=Drosophila melanogaster, GI24663015, Length=250, Percent_Identity=40, Blast_Score=183, Evalue=4e-46, Organism=Drosophila melanogaster, GI24656820, Length=227, Percent_Identity=41.4096916299559, Blast_Score=169, Evalue=5e-42, Organism=Drosophila melanogaster, GI24656825, Length=227, Percent_Identity=41.4096916299559, Blast_Score=169, Evalue=5e-42, Organism=Drosophila melanogaster, GI281363136, Length=251, Percent_Identity=38.2470119521912, Blast_Score=162, Evalue=6e-40, Organism=Drosophila melanogaster, GI78707192, Length=251, Percent_Identity=38.2470119521912, Blast_Score=162, Evalue=6e-40, Organism=Drosophila melanogaster, GI21355121, Length=264, Percent_Identity=33.7121212121212, Blast_Score=147, Evalue=3e-35, Organism=Drosophila melanogaster, GI24644145, Length=231, Percent_Identity=37.2294372294372, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI18859657, Length=236, Percent_Identity=37.2881355932203, Blast_Score=142, Evalue=9e-34, Organism=Drosophila melanogaster, GI24581396, Length=270, Percent_Identity=37.4074074074074, Blast_Score=141, Evalue=2e-33, Organism=Drosophila melanogaster, GI20129529, Length=308, Percent_Identity=32.1428571428571, Blast_Score=140, Evalue=3e-33, Organism=Drosophila melanogaster, GI281360136, Length=230, Percent_Identity=36.0869565217391, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI24644411, Length=230, Percent_Identity=36.0869565217391, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI281360144, Length=230, Percent_Identity=36.0869565217391, Blast_Score=137, Evalue=3e-32, Organism=Drosophila melanogaster, GI281360140, Length=230, Percent_Identity=36.0869565217391, Blast_Score=137, Evalue=3e-32, Organism=Drosophila melanogaster, GI281360142, Length=226, Percent_Identity=36.7256637168142, Blast_Score=136, Evalue=4e-32, Organism=Drosophila melanogaster, GI21357333, Length=226, Percent_Identity=36.7256637168142, Blast_Score=136, Evalue=4e-32, Organism=Drosophila melanogaster, GI281360146, Length=226, Percent_Identity=36.7256637168142, Blast_Score=136, Evalue=5e-32, Organism=Drosophila melanogaster, GI281360138, Length=226, Percent_Identity=36.7256637168142, Blast_Score=136, Evalue=5e-32, Organism=Drosophila melanogaster, GI17864540, Length=212, Percent_Identity=38.6792452830189, Blast_Score=134, Evalue=2e-31, Organism=Drosophila melanogaster, GI28573010, Length=212, Percent_Identity=38.2075471698113, Blast_Score=133, Evalue=4e-31, Organism=Drosophila melanogaster, GI28571849, Length=265, Percent_Identity=36.9811320754717, Blast_Score=130, Evalue=2e-30, Organism=Drosophila melanogaster, GI28571847, Length=265, Percent_Identity=36.9811320754717, Blast_Score=130, Evalue=2e-30, Organism=Drosophila melanogaster, GI20129423, Length=237, Percent_Identity=34.1772151898734, Blast_Score=130, Evalue=2e-30, Organism=Drosophila melanogaster, GI24639486, Length=191, Percent_Identity=34.0314136125654, Blast_Score=101, Evalue=2e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR005936 - InterPro: IPR011546 - InterPro: IPR000642 [H]
Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]
EC number: 3.4.24.- [C]
Molecular weight: Translated: 70753; Mature: 70622
Theoretical pI: Translated: 5.42; Mature: 5.42
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAQNNDNKNNMIKNIIFWILIIGGMLLLFNGINDTNGSSKNINYSTFISKLKDNQISVID CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEE VDGRTITGKTNEGESFVTYAPLLDGSLVNKLEDSNAIVKAKAPEKPNIFLAFLLNWLPML ECCEEEECCCCCCCCEEEECCHHCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHH LIFGFFIYMMVKAGGGSKGGPFSVGKSKAKLLGEDEIKVTLDDVAGVDEAKEEVAEIVDF HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHHHHH LREPKKYEKIGGKIPKGVLMVGPPGTGKTLLARAIAGEAKVPFFSISGSDFVEMFVGVGA HHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCH SRVRDMFEQAKKKAPCLVFIDEIDAVGRHRGSGMGGGNDEREQTLNQMLVEMDGFADNEG HHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC VIVIAATNRPDVLDRALLRPGRFDRQVTVGLPTVKGREAILKVHMKKVALGEDVRADWIA EEEEEECCCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHEE RGTPGFSGAELANLVNEAALFAARESKDKVSMADFEKAKDKILMGSERRSMAMTEKEKRL CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHH TAYHEAGHAIIGRLMPEHDPVYKVSIIPRGRALGVTMYMPEGDTVSQSRLVLRGRLCSIF HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH GGRIAEELIFGYDHVTTGASNDIQVATDIARNYVARWGLSDAMGTILYDVEDEGPFGGSG HHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHCCEEEEEECCCCCCCCCC GKSVKLSDSTIREVDTEVRKLIATSYAKAKQLLEKNIDILHAMADALMKYETIDALQVDD CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH LMARRPVREPGEYGDSYKPKDTGKVIAPVVPNEDELEIADDSSLKEDL HHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCHHHCC >Mature Secondary Structure AQNNDNKNNMIKNIIFWILIIGGMLLLFNGINDTNGSSKNINYSTFISKLKDNQISVID CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEE VDGRTITGKTNEGESFVTYAPLLDGSLVNKLEDSNAIVKAKAPEKPNIFLAFLLNWLPML ECCEEEECCCCCCCCEEEECCHHCCHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHH LIFGFFIYMMVKAGGGSKGGPFSVGKSKAKLLGEDEIKVTLDDVAGVDEAKEEVAEIVDF HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEEEEEHHHCCCHHHHHHHHHHHHH LREPKKYEKIGGKIPKGVLMVGPPGTGKTLLARAIAGEAKVPFFSISGSDFVEMFVGVGA HHCCHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCH SRVRDMFEQAKKKAPCLVFIDEIDAVGRHRGSGMGGGNDEREQTLNQMLVEMDGFADNEG HHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC VIVIAATNRPDVLDRALLRPGRFDRQVTVGLPTVKGREAILKVHMKKVALGEDVRADWIA EEEEEECCCCHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHEE RGTPGFSGAELANLVNEAALFAARESKDKVSMADFEKAKDKILMGSERRSMAMTEKEKRL CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHH TAYHEAGHAIIGRLMPEHDPVYKVSIIPRGRALGVTMYMPEGDTVSQSRLVLRGRLCSIF HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHH GGRIAEELIFGYDHVTTGASNDIQVATDIARNYVARWGLSDAMGTILYDVEDEGPFGGSG HHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHCCEEEEEECCCCCCCCCC GKSVKLSDSTIREVDTEVRKLIATSYAKAKQLLEKNIDILHAMADALMKYETIDALQVDD CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH LMARRPVREPGEYGDSYKPKDTGKVIAPVVPNEDELEIADDSSLKEDL HHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]