| Definition | Francisella tularensis subsp. holarctica LVS chromosome, complete genome. |
|---|---|
| Accession | NC_007880 |
| Length | 1,895,994 |
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The map label for this gene is secA [H]
Identifier: 89256747
GI number: 89256747
Start: 1381543
End: 1384263
Strand: Reverse
Name: secA [H]
Synonym: FTL_1458
Alternate gene names: 89256747
Gene position: 1384263-1381543 (Counterclockwise)
Preceding gene: 89256750
Following gene: 89256746
Centisome position: 73.01
GC content: 34.95
Gene sequence:
>2721_bases ATGTTAAGTTTAGTACAGAAAATAATAGGTAGTCGTAACGAAAGATTTATAAAAAAAGTTTCTAGAATAGTTCAAAAAAT TAACTCTTTAGAACCTGAGTTTGAGAAACTTAGTGATGAGCAATTAAAAGCAAAAACTTTTGAATATCGCGAAAGACTTG CAAACGGTGAAATATTAGACAATCTTTTGCCAGAAGCTTTTGCAACCGTTAGAGAAGCTGGAAAGCGTACTAAAAATATG CGTCATTATGATGTTCAGCTGATAGGTGGTATAGTTCTTCATCAAGGTAAAGTTGCTGAGATGAAAACAGGTGAGGGTAA AACTTTAGTTGCCACATTACCAGCTTATCTAAATGCTTTGACTGGTGATGGTGTACATGTAATTACAGTTAATGATTACC TTGCTAAGCGTGATGCTGAGCTAATGAGTGATATTTACGAATTTTTGGGGATGTCTGTAGGTGTAATAGTTGCTGATTTA AATCCCCAGCAACGTAAAGAAGCTTATGCATGTGATATCACTTATGGAACAAACAATGAATTTGGTTTTGATTATCTAAG AGATAATATGGCTTATGAAAAAGAGCAGCAAGTTCAAAGAAGCCGTAACTATGTAATCATAGATGAGGTTGACTCAATTT TGATTGATGAGGCTAGAACACCACTTATCATATCAGGTGCCTCAGATGATAGCTCTGAGATGTATAACCTTTTCAATAGA TTAGTTCCGTACTTAGAAAAGCAAGAAAAAGAAGAAGTTGAAAATGAACAAGAGCAAAGAGATTTTTATGTAGATGAAAA ATCCAAAAATGCTTATCTAACTGAAAAAGGTTATGCAAAAATTGAGAATATGCTCAAAAAAGAAGGTATTCTTGAAGAAG ATGATAACCTTTATAGCCCTCACAATATTACAAAAATGCATTACTTAAATGCATGTCTAAGAGCTCATTCGTTGTATCAA CTTAATATTGATTATATTGTGAGAGATCAGGAAATAGTTATTATTGATGAAAGTACTGGTAGGGCAATGCCTGGTCGCAG ATGGTCAGATGGTTTGCATCAGGCAATAGAGGCTAAAGAGGGCGTCAAAATTAATGCTGAAAATCAAACAATGGCATCTA TTACCTTCCAAAATTTCTTTAAATTATATAACAAAATTGCTGGTATGACTGGTACTGCTGATACTGAGGCATTTGAGCTT CATTCTATCTATGGTTTAGAGGTAATTATTATACCAACTAATAAACCGATGATTAGAAAAGATCATCATGATGAGATATA TGGTAGTGTAAGAGAAAAATTTGATGCTATAGTTGAGGATATTAAGGAGAGAATTTCAAAAGGTCAGCCGGTACTAGTTG GTACAGCATCTATTGAAGCATCTGAAGTATTATCAACGTTGTTGAAAAAGAAAAAAATCAGACATAATGTTTTGAACGCT AAACAACATGAGAAAGAAGCTAGTATTATTGCCATGGCTGGCTACCCAGATAATGTGACAATCGCAACGAATATGGCAGG TCGTGGTACAGACATTATTTTAGGCGGTAATTTAGAGGTTGAAATAGCACAGCTTGAGGATCCTACACCAGAAGATATTG CTCAAATAAAAGCAGAATGGTTAAAGCGTAATGAAGCTGTTAAGAAAGCTGGTGGACTATGTATCATTGGTTCAGAAAGA CATGATTCCCGCAGGATCGATAATCAGCTAAGAGGTCGTGCTGCTCGTCAGGGTGATCCTGGTGAGAGTAAATTCTATCT ATCTATGGATGATAATCTTTTGCGAATTTTTGCTTCTCAAAGTATGGCAGAAAGGGTTAAAAAAGGTCTAAAAGGTGGTG AGTCACTAGCTTTTGGGTTTATGTCAAAAGTTATATCAAAAGCACAGGGTAAGGTAGAGAGTTATCATTTTGATATCCGT AAGAATCTATTAGAGTATGACAATGTTGTTAATACACAACGTAAAGTTATTTATGAGCAAAGACAGTCATTCTTAGAAGC TGAAGATGTTAGTGATATTCTTGCTGATATTCGTATTGATGTGGCTGAGCAGTTGTTTCATGATTATGTATCTGCTGGTT CCATGCATGAACTGTGGGATCTTGAAGGCTTAGAGAAGGCACTTAAATCTGACTTTATGATTGAGCTTGATCTACAGAAG CTTTATGAAGAAGATGATAGCTTAGGAGAAGAAGATCTTAAGAGGCTAGTAAGAGAAGCTATAGAAATTGAATTTGTTGA AAAAACCAAGAATTTAGATTCAGGCGCTGTGAGACAATTTGAGAAATTCTCATTATTACAATCTCTTGATACTCATTGGC GTGAGCATTTGAGTTCAATAGACCATTTACGTAATAGTATAAATCTACGTGGTTATGCTCAAAAAGATCCAAAAAATGAG TATAAAAAAGAAGCCTTTGAGCTTTTCTCAACTATGTTAGATAATTTCAAATATGAGGTTATATCTTCACTTGCTAAGAT TAGAATTGCTACTGAAGAAGAAACGCAAAGAGCTCAGCAAGAATGGCAAGAATCTATGAGTGATATTAAAGCTGAGCATG AAAGTGTGATTGATAACAATCAAAGACATGATGAGGATGAGCAAGAAGAGGCTCCAAAAGTTCAGCAAGTTAGAAGAGAA GGTCCAAAAGTTAAAAGAAATGATCCATGTCCTTGTGGCTCAGGTAAGAAATATAAACAGTGTCATGGTAAGGTTGAGTA A
Upstream 100 bases:
>100_bases AATAGCTCTATCTTAATTTAAATTTCTTATAAACTCTATATAATGTATCTTCAGAGTATTATATTTATATAAATTATATA AAAAAGTCGGTTAATAAGGG
Downstream 100 bases:
>100_bases TTATTACTAGTTAAGAATCTCTATTTTTTTATAAAAATACTAAACAATAATTAATCTTTTTTCCTGGCGTAATTTTTTAT TATTTTTATGACAAATAAAT
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 906; Mature: 906
Protein sequence:
>906_residues MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNM RHYDVQLIGGIVLHQGKVAEMKTGEGKTLVATLPAYLNALTGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADL NPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNR LVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQ LNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFEL HSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNA KQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSER HDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQSMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIR KNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVSAGSMHELWDLEGLEKALKSDFMIELDLQK LYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNE YKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRRE GPKVKRNDPCPCGSGKKYKQCHGKVE
Sequences:
>Translated_906_residues MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNM RHYDVQLIGGIVLHQGKVAEMKTGEGKTLVATLPAYLNALTGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADL NPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNR LVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQ LNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFEL HSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNA KQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSER HDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQSMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIR KNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVSAGSMHELWDLEGLEKALKSDFMIELDLQK LYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNE YKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRRE GPKVKRNDPCPCGSGKKYKQCHGKVE >Mature_906_residues MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNM RHYDVQLIGGIVLHQGKVAEMKTGEGKTLVATLPAYLNALTGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADL NPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNR LVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQ LNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFEL HSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNA KQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSER HDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQSMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIR KNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVSAGSMHELWDLEGLEKALKSDFMIELDLQK LYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNE YKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRRE GPKVKRNDPCPCGSGKKYKQCHGKVE
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=908, Percent_Identity=56.1674008810573, Blast_Score=1061, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 103591; Mature: 103591
Theoretical pI: Translated: 5.09; Mature: 5.09
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILD CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHH NLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMKTGEGKTLVATLPAYLNAL HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEHHHHHHHH TGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADLNPQQRKEAYACDITYGTNNE CCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCEEEEEEECCCCC FGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNR CCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH LVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSP HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCC HNITKMHYLNACLRAHSLYQLNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKE CCCHHHHHHHHHHHHCCEEEEEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHCC GVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPMIRK CCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEECEEEEEEECCCCCCCC DHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNA CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCH KQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEW HHHHCCCCEEEEECCCCCEEEEECCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHH LKRNEAVKKAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQ HHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHH SMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQ HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RQSFLEAEDVSDILADIRIDVAEQLFHDYVSAGSMHELWDLEGLEKALKSDFMIELDLQK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEHHH LYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSI HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH DHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQ HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHH EWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRREGPKVKRNDPCPCGSGKKYKQ HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCHHHH CHGKVE HCCCCC >Mature Secondary Structure MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILD CHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHH NLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMKTGEGKTLVATLPAYLNAL HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEHHHHHHHH TGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADLNPQQRKEAYACDITYGTNNE CCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCEEEEEEECCCCC FGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNR CCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH LVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSP HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCC HNITKMHYLNACLRAHSLYQLNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKE CCCHHHHHHHHHHHHCCEEEEEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHCC GVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPMIRK CCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEECEEEEEEECCCCCCCC DHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNA CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCH KQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEW HHHHCCCCEEEEECCCCCEEEEECCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHH LKRNEAVKKAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQ HHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHH SMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQ HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RQSFLEAEDVSDILADIRIDVAEQLFHDYVSAGSMHELWDLEGLEKALKSDFMIELDLQK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEHHH LYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSI HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH DHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQ HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHH EWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRREGPKVKRNDPCPCGSGKKYKQ HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCHHHH CHGKVE HCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA