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The map label for this gene is uvrC [H]

Identifier: 89256741

GI number: 89256741

Start: 1373836

End: 1375674

Strand: Reverse

Name: uvrC [H]

Synonym: FTL_1448

Alternate gene names: 89256741

Gene position: 1375674-1373836 (Counterclockwise)

Preceding gene: 89256744

Following gene: 89256740

Centisome position: 72.56

GC content: 33.99

Gene sequence:

>1839_bases
ATGATTGTAGATAATTCTAAAGATTTTGATTTAAAAAGTTTCTTGGCGAACTTGACTACACATTCCGGTGTTTATCGTAT
GCTTGATAAACATGGGGAGATAATTTATGTTGGTAAAGCAAAAAATCTTAAAAACCGTATAAACAGTTATTTTTCAAAAG
GTGCTAAAGATAGTAAAACTTTAATGATGGTAGAGCAGATAGCCCGAATTGAGATAACTATTACCCCTAGTGACTATGAA
GCATATTTATTAGAAAATAATCTCATCAAGCAACATCGTCCTAAATACAATATTTTATTTAAAGATGATAAAAGTTACCC
ATATCTGGTAATTTCGCGTGATAAATTCCCTAGAGTATCTTTTTATCGTGGCAAATCAGCATATAAAAAAGGTCAATGTT
TTGGACCTTATGTGTCGATATCATCAGTTAAGAATACTCTAAATACTATTCAAAAAATTTTTCCAATCCGACAATGTGAA
AACTCATACTATAAATCTAGAGTTAGACCATGTTTACAATATCAAATTAAACGCTGTCTAGCACCATGTGTAGGTTTGGT
TTCTCAACAGCAATATGATGAGCAATTAGCAATTCTAAAAAAATTCTTAGCAGGCAAATTCAGTTCTGTTTTAGAAGAAA
TATCAGCGAATATGTATCAGGCATCTGAAGATATGGAGTATGAGAAAGCTCAAGTTTATCGTGATCAATTGGTGGTGTTG
CGTAAATTACAACAGCAACAAATAGTTGATATTCAAGAGGATAAAACGTTTGATGTAATTGGTATATATATGCAAGATAG
CTATGCAAGTATAGCATTATTACAAATTCAAAATGGTGATGTTGTTGCCGATAGACATTGGAGTATAGATGCCAAAGGGC
AGGATAAAACCTCAATTATGCATGCTTTTTTATCACATTTTTATTTAGGAGATGAGATTCGTAATATTTGGCCTAAAAAT
ATAATCCTATCAAAAGTTGAGTTTGCTGATATTACCGATCTTATGAATAGTATTTCACAAAAAATTGGTCAAGCGATAAA
TTGGATAATTGCTCCAGCAGCTGATAATCTCAAGTGGCTCAAGTTAGCAGAAGTAAATGCACGACAAAAGCTAAATATCT
ACACAAGCTCAAAATCTCAGTATCAAAAACGCTTAGAATCACTCAAAGAATTTCTTGAGTCAGAAAAAGATATTAAGCGT
ATTGAATGTTTTGATATCTCACATTTTCAAGGTGAGGCAACCATAGCATCATGTGTCGTATACACAGATGATGGTGAAGA
TCGCAAATCTCATCGCAGATACAATATCAAAGATATCAAATCAGGAGATGACTATGCAGCAATTCATCAAGCAGTATCGC
GTCGAGTTAGTTCAGGGTTAGAGGCTGACAACCTCCCAGATGTAATGATAATAGATGGTGGTAAAGGGCAGATTCATCAA
GCAGAAGCAGTTTTTAGAGAGTATGGAATTCAAGATAAAGTCCAGCTTGTAAGTTTGGGTAAAGGTGTTGAGCGTATAAG
TGGTAAAGAAAAAATCTACAAAGGTTTTGATGATACCGAATATACATTAGATGAACACAATCCAGGATTTTTATTATTAC
GACAAGTTAGGGACTCTGCTCATGATCATGCAATTAAGGGTCAGCGTAAAAAAGTAAGTGCAAATAGACAGTCATCAATT
ATTGAAGAAATAGAAGGAGTTGGACCGAAGCGTCGCAAGGCTTTGATGATGTATTTTGGCGGTTGGCAAGAGTTATCTAG
AGCATCTGTTGATGAGATTGCAAAGGTCAAAGGAATTAGTAAAAAGTTAGCTCAAGAGATTTGGGAGTGCTTTCATTAA

Upstream 100 bases:

>100_bases
TAGTTAAAATACTTAGAGAAATTTAAACTTATGTATTTAATTAGTATAAAAGTTTATATATGTTAACATTTTTCATAAAC
TCAGTGTTTAATAAAATTAG

Downstream 100 bases:

>100_bases
AAATACTAAACATCAGTAGCATAATGGCGTAGAATATTCGCATTTTAAAAATTATCAAATTAAAAAATGAATAAAAAAGG
TTCGCTACTGAGTAATTTAG

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRINSYFSKGAKDSKTLMMVEQIARIEITITPSDYE
AYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCE
NSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISANMYQASEDMEYEKAQVYRDQLVVL
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKN
IILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLESEKDIKR
IECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
AEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSI
IEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH

Sequences:

>Translated_612_residues
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRINSYFSKGAKDSKTLMMVEQIARIEITITPSDYE
AYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCE
NSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISANMYQASEDMEYEKAQVYRDQLVVL
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKN
IILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLESEKDIKR
IECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
AEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSI
IEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH
>Mature_612_residues
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRINSYFSKGAKDSKTLMMVEQIARIEITITPSDYE
AYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVSFYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCE
NSYYKSRVRPCLQYQIKRCLAPCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISANMYQASEDMEYEKAQVYRDQLVVL
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIMHAFLSHFYLGDEIRNIWPKN
IILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWLKLAEVNARQKLNIYTSSKSQYQKRLESLKEFLESEKDIKR
IECFDISHFQGEATIASCVVYTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
AEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSAHDHAIKGQRKKVSANRQSSI
IEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGISKKLAQEIWECFH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=614, Percent_Identity=43.1596091205212, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 70280; Mature: 70280

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRINSYFSKGAKDSKT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCHH
LMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVS
HHHHHHHHEEEEEEECCCCEEEEHHCCHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCE
FYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKRCL
EECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISANMYQASEDMEYEKAQVYRDQLVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIM
HHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEEEECCCEEECCCEEECCCCCHHHHHH
HAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWL
HHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEE
KLAEVNARQKLNIYTSSKSQYQKRLESLKEFLESEKDIKRIECFDISHFQGEATIASCVV
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCCCEEEEEEE
YTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
EECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
AEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSA
HHHHHHHCCCCHHHHHHHHCCCHHHHCCHHHHHCCCCCCCCEECCCCCCCEEHHHHHHHH
HDHAIKGQRKKVSANRQSSIIEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGIS
HHHHHCCCHHHHCCCHHHHHHHHHHCCCCHHHHEEEEEECCHHHHHHCCHHHHHHHHHHH
KKLAQEIWECFH
HHHHHHHHHHCC
>Mature Secondary Structure
MIVDNSKDFDLKSFLANLTTHSGVYRMLDKHGEIIYVGKAKNLKNRINSYFSKGAKDSKT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCHH
LMMVEQIARIEITITPSDYEAYLLENNLIKQHRPKYNILFKDDKSYPYLVISRDKFPRVS
HHHHHHHHEEEEEEECCCCEEEEHHCCHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCE
FYRGKSAYKKGQCFGPYVSISSVKNTLNTIQKIFPIRQCENSYYKSRVRPCLQYQIKRCL
EECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APCVGLVSQQQYDEQLAILKKFLAGKFSSVLEEISANMYQASEDMEYEKAQVYRDQLVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RKLQQQQIVDIQEDKTFDVIGIYMQDSYASIALLQIQNGDVVADRHWSIDAKGQDKTSIM
HHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEEEECCCEEECCCEEECCCCCHHHHHH
HAFLSHFYLGDEIRNIWPKNIILSKVEFADITDLMNSISQKIGQAINWIIAPAADNLKWL
HHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEE
KLAEVNARQKLNIYTSSKSQYQKRLESLKEFLESEKDIKRIECFDISHFQGEATIASCVV
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCCCEEEEEEE
YTDDGEDRKSHRRYNIKDIKSGDDYAAIHQAVSRRVSSGLEADNLPDVMIIDGGKGQIHQ
EECCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
AEAVFREYGIQDKVQLVSLGKGVERISGKEKIYKGFDDTEYTLDEHNPGFLLLRQVRDSA
HHHHHHHCCCCHHHHHHHHCCCHHHHCCHHHHHCCCCCCCCEECCCCCCCEEHHHHHHHH
HDHAIKGQRKKVSANRQSSIIEEIEGVGPKRRKALMMYFGGWQELSRASVDEIAKVKGIS
HHHHHCCCHHHHCCCHHHHHHHHHHCCCCHHHHEEEEEECCHHHHHHCCHHHHHHHHHHH
KKLAQEIWECFH
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA