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The map label for this gene is fabH [H]

Identifier: 89256465

GI number: 89256465

Start: 1083079

End: 1084050

Strand: Reverse

Name: fabH [H]

Synonym: FTL_1141

Alternate gene names: 89256465

Gene position: 1084050-1083079 (Counterclockwise)

Preceding gene: 89256466

Following gene: 89256464

Centisome position: 57.18

GC content: 35.8

Gene sequence:

>972_bases
ATGTTTGCACAAATATTAGGTACAGGAAGTTACTTGCCTGAAAAAATCTTAACTAATGAAGATATAAGTAAATTTGTTGA
TACTTCAGATGAGTGGATCAAACAAAGAGTCGGCATAGAAAGACGCCATTGCGCCAGTGAAGCAGAAACGACAAGTTACA
TGGCTACACATGCAGCTAAAAAGGCTCTTGAAGCGGCACAATTAACTGCTAACGATATTGATATGATAATTGTTGCAACA
AGTACTCCTGATTTCATAATGCCTTCAACAGCGTCAATGGTTCATCAGAATCTACAAATAGATAATTTCAAGGTACGTTG
TTTTGATATATCAGCTGCTTGTAGTGGGTTTGTTTATGCTTTGGATATCGCTAAACAATATATAGAGACAGGTGTTTCAA
AAAACATTCTCGTAATTGGTGCTGAAAAAATGACGCGGGTCCTAGATTGGAATGACCGTTCAACATGTGTACTTTTTGGT
GATGGTGCTGGTGCTGTTGTAATTTCAACAAGCCAAGAAAAAAAGATATTATCATCTTTACTTTTTACAGATGGTTCATG
CTTAGATATGCTTAATGTCCCAAATAATTTACCAACTTCAAGAGGACAAGCTATAAATATTGATCCTTACTTAATAATGG
AAGGTAATAAGGTTTTTAAATTTGCTGTTTCACGCTTATCTTCATTAGCTGATGAGTTAATACAAGAAGCTGGAATAAAA
GCTAGTGATATTGATTGGCTTGTACCTCATCAAGCAAACTATAGAATACTAAACTCAACTGCCAAAAAAATTGACATGCC
AATGTCTAAAGTTGTTACAACACTACAAGATCATGGTAACACTTCTGCAGCATCTATCCCATTAGCCTTAGATCATGCTG
TAAGAACACATCAAATTAAACCTGGCGATACAATTATCTCTGAAGCATTCGGAGCTGGATTTGTCTGGGGTGGTTTTATC
GCGAAGATATAA

Upstream 100 bases:

>100_bases
TTAATCTTTTTTATTCATGCTACAATAAATATTGAGCCATAGGCGAAAAGCTTATGGTTTTTTGTTGTTAATCATAATTT
AAAGTAGGTATAACTATATA

Downstream 100 bases:

>100_bases
TCTTTTATAAATTTACTATTTTTATATAACATAAAAGGAGGATTATTATGTCAAAAACAGCTGTAGTTTTTCCTGGTCAA
GGTTCACAAAAACTAGGGAT

Product: 3-oxoacyl-[acyl carrier protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MFAQILGTGSYLPEKILTNEDISKFVDTSDEWIKQRVGIERRHCASEAETTSYMATHAAKKALEAAQLTANDIDMIIVAT
STPDFIMPSTASMVHQNLQIDNFKVRCFDISAACSGFVYALDIAKQYIETGVSKNILVIGAEKMTRVLDWNDRSTCVLFG
DGAGAVVISTSQEKKILSSLLFTDGSCLDMLNVPNNLPTSRGQAINIDPYLIMEGNKVFKFAVSRLSSLADELIQEAGIK
ASDIDWLVPHQANYRILNSTAKKIDMPMSKVVTTLQDHGNTSAASIPLALDHAVRTHQIKPGDTIISEAFGAGFVWGGFI
AKI

Sequences:

>Translated_323_residues
MFAQILGTGSYLPEKILTNEDISKFVDTSDEWIKQRVGIERRHCASEAETTSYMATHAAKKALEAAQLTANDIDMIIVAT
STPDFIMPSTASMVHQNLQIDNFKVRCFDISAACSGFVYALDIAKQYIETGVSKNILVIGAEKMTRVLDWNDRSTCVLFG
DGAGAVVISTSQEKKILSSLLFTDGSCLDMLNVPNNLPTSRGQAINIDPYLIMEGNKVFKFAVSRLSSLADELIQEAGIK
ASDIDWLVPHQANYRILNSTAKKIDMPMSKVVTTLQDHGNTSAASIPLALDHAVRTHQIKPGDTIISEAFGAGFVWGGFI
AKI
>Mature_323_residues
MFAQILGTGSYLPEKILTNEDISKFVDTSDEWIKQRVGIERRHCASEAETTSYMATHAAKKALEAAQLTANDIDMIIVAT
STPDFIMPSTASMVHQNLQIDNFKVRCFDISAACSGFVYALDIAKQYIETGVSKNILVIGAEKMTRVLDWNDRSTCVLFG
DGAGAVVISTSQEKKILSSLLFTDGSCLDMLNVPNNLPTSRGQAINIDPYLIMEGNKVFKFAVSRLSSLADELIQEAGIK
ASDIDWLVPHQANYRILNSTAKKIDMPMSKVVTTLQDHGNTSAASIPLALDHAVRTHQIKPGDTIISEAFGAGFVWGGFI
AKI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=46.6257668711656, Blast_Score=305, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35211; Mature: 35211

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAQILGTGSYLPEKILTNEDISKFVDTSDEWIKQRVGIERRHCASEAETTSYMATHAAK
CCCEEECCCCCCCHHHHCCHHHHHHHCCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
KALEAAQLTANDIDMIIVATSTPDFIMPSTASMVHQNLQIDNFKVRCFDISAACSGFVYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEEEECHHHCCHHHH
LDIAKQYIETGVSKNILVIGAEKMTRVLDWNDRSTCVLFGDGAGAVVISTSQEKKILSSL
HHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHHH
LFTDGSCLDMLNVPNNLPTSRGQAINIDPYLIMEGNKVFKFAVSRLSSLADELIQEAGIK
HHCCCCCEECCCCCCCCCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
ASDIDWLVPHQANYRILNSTAKKIDMPMSKVVTTLQDHGNTSAASIPLALDHAVRTHQIK
CCCCCEECCCCCCCEEEHHHHHHHCCCHHHHHHHHHHCCCCCCEECCEEHHHHHHHCCCC
PGDTIISEAFGAGFVWGGFIAKI
CCHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MFAQILGTGSYLPEKILTNEDISKFVDTSDEWIKQRVGIERRHCASEAETTSYMATHAAK
CCCEEECCCCCCCHHHHCCHHHHHHHCCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
KALEAAQLTANDIDMIIVATSTPDFIMPSTASMVHQNLQIDNFKVRCFDISAACSGFVYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEEEECHHHCCHHHH
LDIAKQYIETGVSKNILVIGAEKMTRVLDWNDRSTCVLFGDGAGAVVISTSQEKKILSSL
HHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHHH
LFTDGSCLDMLNVPNNLPTSRGQAINIDPYLIMEGNKVFKFAVSRLSSLADELIQEAGIK
HHCCCCCEECCCCCCCCCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
ASDIDWLVPHQANYRILNSTAKKIDMPMSKVVTTLQDHGNTSAASIPLALDHAVRTHQIK
CCCCCEECCCCCCCEEEHHHHHHHCCCHHHHHHHHHHCCCCCCEECCEEHHHHHHHCCCC
PGDTIISEAFGAGFVWGGFIAKI
CCHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA