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The map label for this gene is fabD [H]

Identifier: 89256464

GI number: 89256464

Start: 1082111

End: 1083031

Strand: Reverse

Name: fabD [H]

Synonym: FTL_1140

Alternate gene names: 89256464

Gene position: 1083031-1082111 (Counterclockwise)

Preceding gene: 89256465

Following gene: 89256463

Centisome position: 57.12

GC content: 35.29

Gene sequence:

>921_bases
ATGTCAAAAACAGCTGTAGTTTTTCCTGGTCAAGGTTCACAAAAACTAGGGATGCTCCAAGATTATTATGAAAATTTTGA
AACGTTTAGAAATATAGTCGATGAAGCTAAAGAACACCTTGGCTACGACTTATGGAATATTATTCAAAATGATGAAGAAA
CTCTAAATAAAACAGAGTTTACCCAGCCAGCATTACTTGCAACTAGTTATGCAATATATGAAGTCTTAAAAGAGCAAAAG
CCAGACTTAAAAATAGCATACTTTGCAGGACATAGTTTAGGTGAATACACTGCCCTACTTGCTGCTGGATGTATTTCATA
CAAAGATGCTTTACAACTTGTATCTACACGTGGCAAATTAATGCAAAATGCTGTTACTGACAAAGAATGTGCTATGAGCG
CAATTCTAGGTTTATCAAATGAGGATGTAATCAAATCTTGTCAAGAAGCTAGTGATGCTGGAATTGTTGAAGCTGCAAAC
TTTAACTCAACAGGACAAGTTGTCATCTCTGGGGAAAAAGCTGCTGTTGAGAAAGCTAATACAATAGCTAAAGAAAAAGG
TGCAAAACGCGCGCAGATACTTGCTGTTAGCGTACCTTCACATTGTTCTTTAATGAAGGATGCTGCAGATAAATTTGAAG
CAGAGTTAAACAAAGTAGAATTTAAAGAGCCTACTACCGCTGTTGTACAAAACTTTGACGCCAAATCACACGCAAATCCA
GCTGAAATAAAAACTGCTGTTATTAAACAACTATACAAGCCAGTACTTTGGACACAATCTATCGAAGAGCTAGTCAAACT
TGGAGTCACAGAAGTTATCGAATGTGGTCCTAACAAGGTCTTATCTGGACTAATCAAAAGAATAGATAAATCAATAGATA
TAAAAGATACAAACAGTATTGATAGTTTAGAAAATATTTAA

Upstream 100 bases:

>100_bases
CTGAAGCATTCGGAGCTGGATTTGTCTGGGGTGGTTTTATCGCGAAGATATAATCTTTTATAAATTTACTATTTTTATAT
AACATAAAAGGAGGATTATT

Downstream 100 bases:

>100_bases
AAGGAGATAATAAATGTCTTTGAATGAAAAAGTTGCTCTTGTGACAGGTGCAAGTAGAGGTATTGGTTTTGAAGTTGCTC
ATGCATTAGCAAGCAAAGGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSKTAVVFPGQGSQKLGMLQDYYENFETFRNIVDEAKEHLGYDLWNIIQNDEETLNKTEFTQPALLATSYAIYEVLKEQK
PDLKIAYFAGHSLGEYTALLAAGCISYKDALQLVSTRGKLMQNAVTDKECAMSAILGLSNEDVIKSCQEASDAGIVEAAN
FNSTGQVVISGEKAAVEKANTIAKEKGAKRAQILAVSVPSHCSLMKDAADKFEAELNKVEFKEPTTAVVQNFDAKSHANP
AEIKTAVIKQLYKPVLWTQSIEELVKLGVTEVIECGPNKVLSGLIKRIDKSIDIKDTNSIDSLENI

Sequences:

>Translated_306_residues
MSKTAVVFPGQGSQKLGMLQDYYENFETFRNIVDEAKEHLGYDLWNIIQNDEETLNKTEFTQPALLATSYAIYEVLKEQK
PDLKIAYFAGHSLGEYTALLAAGCISYKDALQLVSTRGKLMQNAVTDKECAMSAILGLSNEDVIKSCQEASDAGIVEAAN
FNSTGQVVISGEKAAVEKANTIAKEKGAKRAQILAVSVPSHCSLMKDAADKFEAELNKVEFKEPTTAVVQNFDAKSHANP
AEIKTAVIKQLYKPVLWTQSIEELVKLGVTEVIECGPNKVLSGLIKRIDKSIDIKDTNSIDSLENI
>Mature_305_residues
SKTAVVFPGQGSQKLGMLQDYYENFETFRNIVDEAKEHLGYDLWNIIQNDEETLNKTEFTQPALLATSYAIYEVLKEQKP
DLKIAYFAGHSLGEYTALLAAGCISYKDALQLVSTRGKLMQNAVTDKECAMSAILGLSNEDVIKSCQEASDAGIVEAANF
NSTGQVVISGEKAAVEKANTIAKEKGAKRAQILAVSVPSHCSLMKDAADKFEAELNKVEFKEPTTAVVQNFDAKSHANPA
EIKTAVIKQLYKPVLWTQSIEELVKLGVTEVIECGPNKVLSGLIKRIDKSIDIKDTNSIDSLENI

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=318, Percent_Identity=27.9874213836478, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1787334, Length=304, Percent_Identity=48.6842105263158, Blast_Score=270, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71984332, Length=272, Percent_Identity=29.0441176470588, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=28.9036544850498, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=33.2225913621262, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33501; Mature: 33370

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAVVFPGQGSQKLGMLQDYYENFETFRNIVDEAKEHLGYDLWNIIQNDEETLNKTEF
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHC
TQPALLATSYAIYEVLKEQKPDLKIAYFAGHSLGEYTALLAAGCISYKDALQLVSTRGKL
CCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQNAVTDKECAMSAILGLSNEDVIKSCQEASDAGIVEAANFNSTGQVVISGEKAAVEKAN
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCHHHHHHHH
TIAKEKGAKRAQILAVSVPSHCSLMKDAADKFEAELNKVEFKEPTTAVVQNFDAKSHANP
HHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCH
AEIKTAVIKQLYKPVLWTQSIEELVKLGVTEVIECGPNKVLSGLIKRIDKSIDIKDTNSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
DSLENI
HHHHCC
>Mature Secondary Structure 
SKTAVVFPGQGSQKLGMLQDYYENFETFRNIVDEAKEHLGYDLWNIIQNDEETLNKTEF
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHC
TQPALLATSYAIYEVLKEQKPDLKIAYFAGHSLGEYTALLAAGCISYKDALQLVSTRGKL
CCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQNAVTDKECAMSAILGLSNEDVIKSCQEASDAGIVEAANFNSTGQVVISGEKAAVEKAN
HHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCHHHHHHHH
TIAKEKGAKRAQILAVSVPSHCSLMKDAADKFEAELNKVEFKEPTTAVVQNFDAKSHANP
HHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCH
AEIKTAVIKQLYKPVLWTQSIEELVKLGVTEVIECGPNKVLSGLIKRIDKSIDIKDTNSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
DSLENI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]