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The map label for this gene is aes [C]

Identifier: 89256402

GI number: 89256402

Start: 1019181

End: 1021013

Strand: Direct

Name: aes [C]

Synonym: FTL_1067

Alternate gene names: 89256402

Gene position: 1019181-1021013 (Clockwise)

Preceding gene: 89256401

Following gene: 89256403

Centisome position: 53.75

GC content: 33.33

Gene sequence:

>1833_bases
ATGTGGGCAATTGTAGGAAGTAGTGGTTTTGAATCTTTTGATGACTTTGAGATTATAGAAGAATTGCCACGAGAAACGCC
ATTTGGTTTGTGTTCGAATGGTTTATTTAAAATAAAAGTTGAAGATAAAGAGGTATTATTTCTCAATAGAACTGGTTTGG
GTCAGAATATATTACCCCATCAAATAAACTACAAAGCTAATATTTACGCACTAAAGAAATATGGAGCTACTTCAATTATT
GCTTTATCTTCGGTTAGAAGCTTAAGAGAAGAGCTAAAACCTGGTGACATGGTTATTCCATATCAGTTTATCGATAGAAC
CAAATCTCTAAGAGAGTTTACATTTTGTGAACAAGGATTGCTAAACTATGTTTCACTTTCAAAACCTATAACAGAGAGTA
TTGCCGAAGAGATTAGAGCAAAGAAAAAAGAATTTGATTTTGAGATTCATTTTAAACAAAGTTATGTCTGTATCGAAGGT
CCACAGTTTCCAACTATAATCGATGCTAAATGTTTTCAAAGTATGGGTGGTGGTGTTATAGGTATGACAGCATTTCCAGA
ATTTGCTTTAGCAAGGGAAGCTGGATTGAACTATATTAGCTGTAATTTTATTGTTGACTATGTGCCTTGGTCGTATGATG
TTAGAAATTTATATAACGTTTTAGAAATACGTGAAACAAATAATCTCAAAGCAGAAAAATTAGTTAAATGGCTAGTAAAT
AATTTACCATTTTATGCTGAGAATGATTGTCATGAGTTAGGTATTGCTAGATATCTATCAACACCAATAGAATCATTACC
ACCAAATAAAAAAGCATGGCTAAAAGTTATCGCTAAAGATAATTCTGAACATGAAGAAGCACTTGAGGCTGAAATTCTTA
AAAAAGTTCCAGATTTATATGGTGGTATTAAAACTATACCAGCAAAATTACAAGATTTATTAACCTTTATCGGTAAATAT
GATCGTGAGGGAAATAGAAAAGATTTAGAAGCAACTCGAAAAGCTGCTGCATCATTAGATCTATATAGCTACCCTAAAGT
TGATCTAGAAAATGTTGAAGATATCCAAATCACTCATGATGATGGTCATAATATTCCAGTTAGAGTATATAATCCTAAAG
TTGATGAAAAACTCAAAGTGATAATTTTTTCTCATGGTGGTGGCTTTGTATCTGGTACTTTAGATTCGTTTGATGCTTTT
TGTCGCAAACTTGCACTAACTACGAATAGGGTAGTTTTCTCGGTTGATTATCGCCTAGCTCCGGAGCATAAATTCCCAGC
AGGTCTAAATGATGTTGAATTTGTTGCTGAACATATTTTCAAACATTCCAAGAAATTTGGAGTTTCCAAAAAGAAATTTA
CACTGATGGGCGACAGTGCTGGAGCTAACTTAACTGTCTTAGCGACATATAATTTACTACAGAAAGACACTGTTAAAATT
GCTAATAATATTATCCTATATCCTTCAGTTGATTTATCGCACATGCCTACAAAATCACTAGAAGATTTTGCTAGTGGTTA
TATCTTAACTAAAGCGAAAACGATGTGGTACTCCGAGCTATATGTGCCTGAAAATATCGATAAACGCTCTCCTGAAGTTT
CTCCTTTTTATATTAAAGAATTAGATAATATGCCGAGAACTTTAGTCATGACGGCAGGTTATGACCCACTAAGAGATGAA
GGGTTACTATTTGCTGAAAGGCTTCTTAGACATGATGTTGAGGTGCAGCACTATCATTTTGATAGTTTGGTTCATGGTTT
TATCAATTTCTCAAAACTTATTCCAAAAGAAATGGATGTTCTGCATTCAAGAGTTGTTAAATTTCTTGGCTAA

Upstream 100 bases:

>100_bases
TAAAGGTGTTGGTGTAGTAAATACTGGTGATAAGTTTAAAATCGAGTTATTTTGTAGAGATAAAAAAATATTAGCAACAA
CTTTTTAGGTATATAAAAAT

Downstream 100 bases:

>100_bases
TTATGAAAAACTACCTACTACAAATCGAATACTTTGGCAAAAACTACTGTGGTTGGCAAAGACAATCTCATTCACTAAGT
GTGCAAGAAGAGCTTGAAAA

Product: hypothetical protein

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MWAIVGSSGFESFDDFEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTGLGQNILPHQINYKANIYALKKYGATSII
ALSSVRSLREELKPGDMVIPYQFIDRTKSLREFTFCEQGLLNYVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEG
PQFPTIIDAKCFQSMGGGVIGMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVRNLYNVLEIRETNNLKAEKLVKWLVN
NLPFYAENDCHELGIARYLSTPIESLPPNKKAWLKVIAKDNSEHEEALEAEILKKVPDLYGGIKTIPAKLQDLLTFIGKY
DREGNRKDLEATRKAAASLDLYSYPKVDLENVEDIQITHDDGHNIPVRVYNPKVDEKLKVIIFSHGGGFVSGTLDSFDAF
CRKLALTTNRVVFSVDYRLAPEHKFPAGLNDVEFVAEHIFKHSKKFGVSKKKFTLMGDSAGANLTVLATYNLLQKDTVKI
ANNIILYPSVDLSHMPTKSLEDFASGYILTKAKTMWYSELYVPENIDKRSPEVSPFYIKELDNMPRTLVMTAGYDPLRDE
GLLFAERLLRHDVEVQHYHFDSLVHGFINFSKLIPKEMDVLHSRVVKFLG

Sequences:

>Translated_610_residues
MWAIVGSSGFESFDDFEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTGLGQNILPHQINYKANIYALKKYGATSII
ALSSVRSLREELKPGDMVIPYQFIDRTKSLREFTFCEQGLLNYVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEG
PQFPTIIDAKCFQSMGGGVIGMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVRNLYNVLEIRETNNLKAEKLVKWLVN
NLPFYAENDCHELGIARYLSTPIESLPPNKKAWLKVIAKDNSEHEEALEAEILKKVPDLYGGIKTIPAKLQDLLTFIGKY
DREGNRKDLEATRKAAASLDLYSYPKVDLENVEDIQITHDDGHNIPVRVYNPKVDEKLKVIIFSHGGGFVSGTLDSFDAF
CRKLALTTNRVVFSVDYRLAPEHKFPAGLNDVEFVAEHIFKHSKKFGVSKKKFTLMGDSAGANLTVLATYNLLQKDTVKI
ANNIILYPSVDLSHMPTKSLEDFASGYILTKAKTMWYSELYVPENIDKRSPEVSPFYIKELDNMPRTLVMTAGYDPLRDE
GLLFAERLLRHDVEVQHYHFDSLVHGFINFSKLIPKEMDVLHSRVVKFLG
>Mature_610_residues
MWAIVGSSGFESFDDFEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTGLGQNILPHQINYKANIYALKKYGATSII
ALSSVRSLREELKPGDMVIPYQFIDRTKSLREFTFCEQGLLNYVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEG
PQFPTIIDAKCFQSMGGGVIGMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVRNLYNVLEIRETNNLKAEKLVKWLVN
NLPFYAENDCHELGIARYLSTPIESLPPNKKAWLKVIAKDNSEHEEALEAEILKKVPDLYGGIKTIPAKLQDLLTFIGKY
DREGNRKDLEATRKAAASLDLYSYPKVDLENVEDIQITHDDGHNIPVRVYNPKVDEKLKVIIFSHGGGFVSGTLDSFDAF
CRKLALTTNRVVFSVDYRLAPEHKFPAGLNDVEFVAEHIFKHSKKFGVSKKKFTLMGDSAGANLTVLATYNLLQKDTVKI
ANNIILYPSVDLSHMPTKSLEDFASGYILTKAKTMWYSELYVPENIDKRSPEVSPFYIKELDNMPRTLVMTAGYDPLRDE
GLLFAERLLRHDVEVQHYHFDSLVHGFINFSKLIPKEMDVLHSRVVKFLG

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=252, Percent_Identity=35.3174603174603, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI68299767, Length=316, Percent_Identity=31.6455696202532, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI157041239, Length=320, Percent_Identity=26.25, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI206597554, Length=215, Percent_Identity=32.093023255814, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI68051721, Length=326, Percent_Identity=24.5398773006135, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI61966717, Length=287, Percent_Identity=25.0871080139373, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI226423947, Length=334, Percent_Identity=23.9520958083832, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI1786682, Length=234, Percent_Identity=26.0683760683761, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71980569, Length=238, Percent_Identity=28.1512605042017, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71996133, Length=173, Percent_Identity=32.9479768786127, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540028, Length=173, Percent_Identity=33.5260115606936, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567059, Length=266, Percent_Identity=27.0676691729323, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI72001146, Length=153, Percent_Identity=34.640522875817, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115533412, Length=121, Percent_Identity=29.7520661157025, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533410, Length=121, Percent_Identity=29.7520661157025, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323045, Length=286, Percent_Identity=30.0699300699301, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20130079, Length=261, Percent_Identity=34.8659003831418, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI221459247, Length=191, Percent_Identity=30.3664921465969, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 69416; Mature: 69416

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWAIVGSSGFESFDDFEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTGLGQNILPH
CEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCC
QINYKANIYALKKYGATSIIALSSVRSLREELKPGDMVIPYQFIDRTKSLREFTFCEQGL
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHH
LNYVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEGPQFPTIIDAKCFQSMGGGVI
HHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECEEEEEECCCCCCEECHHHHHHHCCCEE
GMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVRNLYNVLEIRETNNLKAEKLVKWLVN
EECCCCHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
NLPFYAENDCHELGIARYLSTPIESLPPNKKAWLKVIAKDNSEHEEALEAEILKKVPDLY
CCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
GGIKTIPAKLQDLLTFIGKYDREGNRKDLEATRKAAASLDLYSYPKVDLENVEDIQITHD
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
DGHNIPVRVYNPKVDEKLKVIIFSHGGGFVSGTLDSFDAFCRKLALTTNRVVFSVDYRLA
CCCCCCEEEECCCCCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHCCCEEEEEEEEEEC
PEHKFPAGLNDVEFVAEHIFKHSKKFGVSKKKFTLMGDSAGANLTVLATYNLLQKDTVKI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECHHHHHHHHH
ANNIILYPSVDLSHMPTKSLEDFASGYILTKAKTMWYSELYVPENIDKRSPEVSPFYIKE
HCCEEEEECCCCCCCCCHHHHHHHCCEEEEEHHHHHHHEEECCCCCCCCCCCCCCHHHHH
LDNMPRTLVMTAGYDPLRDEGLLFAERLLRHDVEVQHYHFDSLVHGFINFSKLIPKEMDV
HCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCHHHHHH
LHSRVVKFLG
HHHHHHHHCC
>Mature Secondary Structure
MWAIVGSSGFESFDDFEIIEELPRETPFGLCSNGLFKIKVEDKEVLFLNRTGLGQNILPH
CEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCC
QINYKANIYALKKYGATSIIALSSVRSLREELKPGDMVIPYQFIDRTKSLREFTFCEQGL
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHH
LNYVSLSKPITESIAEEIRAKKKEFDFEIHFKQSYVCIEGPQFPTIIDAKCFQSMGGGVI
HHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECEEEEEECCCCCCEECHHHHHHHCCCEE
GMTAFPEFALAREAGLNYISCNFIVDYVPWSYDVRNLYNVLEIRETNNLKAEKLVKWLVN
EECCCCHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
NLPFYAENDCHELGIARYLSTPIESLPPNKKAWLKVIAKDNSEHEEALEAEILKKVPDLY
CCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHH
GGIKTIPAKLQDLLTFIGKYDREGNRKDLEATRKAAASLDLYSYPKVDLENVEDIQITHD
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
DGHNIPVRVYNPKVDEKLKVIIFSHGGGFVSGTLDSFDAFCRKLALTTNRVVFSVDYRLA
CCCCCCEEEECCCCCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHCCCEEEEEEEEEEC
PEHKFPAGLNDVEFVAEHIFKHSKKFGVSKKKFTLMGDSAGANLTVLATYNLLQKDTVKI
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECHHHHHHHHH
ANNIILYPSVDLSHMPTKSLEDFASGYILTKAKTMWYSELYVPENIDKRSPEVSPFYIKE
HCCEEEEECCCCCCCCCHHHHHHHCCEEEEEHHHHHHHEEECCCCCCCCCCCCCCHHHHH
LDNMPRTLVMTAGYDPLRDEGLLFAERLLRHDVEVQHYHFDSLVHGFINFSKLIPKEMDV
HCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCHHHHHH
LHSRVVKFLG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]