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The map label for this gene is ycgM [H]

Identifier: 89256401

GI number: 89256401

Start: 1018575

End: 1019168

Strand: Direct

Name: ycgM [H]

Synonym: FTL_1066

Alternate gene names: 89256401

Gene position: 1018575-1019168 (Clockwise)

Preceding gene: 89256400

Following gene: 89256402

Centisome position: 53.72

GC content: 28.11

Gene sequence:

>594_bases
ATGCAAATTGATCTAACAAAGTCAAAAGTAATTTGTGTCGGAAGAAATTACGTTGAGCATATTCATGAGCTTAATAATGA
AGTTCCTGACAATCCAGTTATTTTTATAAAACCTAATTCAAGTATAACTAAAACTCTAAAATTATCTTCAAAAAGAGAAA
CTCACTATGAATGTGAAATAGTTTTTATTTTTGATAATAATTCAAATATAAAAGCCGTCGGTTTGGGATTAGATTTGACT
GATATAAATTTACAGTCAAAACTTAAGGCAAAAGGACTACCATGGGAATTGGCAAAAGCTTTTGATAATAGTGCGGTGAT
TAGTGAGTTTGTTGCAATAGATAGTAAAGATATTGCATTTTTGAATTTCAAAGCATACAAGAATGATATTCTAATTCAGC
AAGGTAGTTATGATTTAATGATCTATAAACCTCAACAAATTATAGATTTTTTGCAGCAAAATGAAATCTCAATATGTGAA
AATGATTTACTAATGACTGGAACTCCTAAAGGTGTTGGTGTAGTAAATACTGGTGATAAGTTTAAAATCGAGTTATTTTG
TAGAGATAAAAAAATATTAGCAACAACTTTTTAG

Upstream 100 bases:

>100_bases
AGCCGATGAAACAGTTAGAAAAGTATATCTAGGTGAAGATTTCAAATTATAAAAAATTTAATTATAAGTTTTATTGTCTA
TTTGTTGAGGAAAGCAAAAA

Downstream 100 bases:

>100_bases
GTATATAAAAATATGTGGGCAATTGTAGGAAGTAGTGGTTTTGAATCTTTTGATGACTTTGAGATTATAGAAGAATTGCC
ACGAGAAACGCCATTTGGTT

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEIVFIFDNNSNIKAVGLGLDLT
DINLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAFLNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICE
NDLLMTGTPKGVGVVNTGDKFKIELFCRDKKILATTF

Sequences:

>Translated_197_residues
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEIVFIFDNNSNIKAVGLGLDLT
DINLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAFLNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICE
NDLLMTGTPKGVGVVNTGDKFKIELFCRDKKILATTF
>Mature_197_residues
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEIVFIFDNNSNIKAVGLGLDLT
DINLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAFLNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICE
NDLLMTGTPKGVGVVNTGDKFKIELFCRDKKILATTF

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=188, Percent_Identity=32.4468085106383, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI215422413, Length=188, Percent_Identity=32.4468085106383, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI13654274, Length=188, Percent_Identity=32.4468085106383, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI156231349, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI40786394, Length=198, Percent_Identity=29.2929292929293, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787428, Length=197, Percent_Identity=33.502538071066, Blast_Score=110, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324161, Length=236, Percent_Identity=31.7796610169492, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571789, Length=186, Percent_Identity=30.6451612903226, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 22278; Mature: 22278

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEI
CEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEE
VFIFDNNSNIKAVGLGLDLTDINLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAF
EEEEECCCCEEEEEEEEEEEECCHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCCCEEE
LNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICENDLLMTGTPKGVGVVNTGDK
EEEEECCCEEEEECCCEEEEEECHHHHHHHHHCCCCEEECCCEEEECCCCCCEEEECCCE
FKIELFCRDKKILATTF
EEEEEEEECCEEEEECC
>Mature Secondary Structure
MQIDLTKSKVICVGRNYVEHIHELNNEVPDNPVIFIKPNSSITKTLKLSSKRETHYECEI
CEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCCCCEEEEE
VFIFDNNSNIKAVGLGLDLTDINLQSKLKAKGLPWELAKAFDNSAVISEFVAIDSKDIAF
EEEEECCCCEEEEEEEEEEEECCHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCCCEEE
LNFKAYKNDILIQQGSYDLMIYKPQQIIDFLQQNEISICENDLLMTGTPKGVGVVNTGDK
EEEEECCCEEEEECCCEEEEEECHHHHHHHHHCCCCEEECCCEEEECCCCCCEEEECCCE
FKIELFCRDKKILATTF
EEEEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]