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The map label for this gene is kdsC [H]

Identifier: 89256397

GI number: 89256397

Start: 1015719

End: 1016267

Strand: Direct

Name: kdsC [H]

Synonym: FTL_1062

Alternate gene names: 89256397

Gene position: 1015719-1016267 (Clockwise)

Preceding gene: 89256396

Following gene: 89256398

Centisome position: 53.57

GC content: 31.69

Gene sequence:

>549_bases
ATGAAAATAAATCACTCAAGAAACTCAATAAATATTAAACTGTTGATTCTCGATGTAGATGGTGTGTTAACAGATGGCAA
AATAATAGTAACTAATGATGGTGACGAGCTTAAAAATTTTGATGTCAAAGATGGTTTAGGGATTGTCCTTATGCAGAAAC
TTGGAATCAAAGTTGCTATTATCACAGGTAAACAATCAAAAATTGTCGATGATAGATTTAAAAACTTAGGATTAGATCCT
GAAGATATTTTGCAAGGTCAAAAAAATAAACTAAAAGCTTATGAATTTCTCAAGTCAAAATATAAGCTAAATGATAGTGA
TATAGCATATATGGGAGATGATTTGCCAGATATAATCTTGATGAATAAAGTAGCCATTTCTGCAGCACCAGCTGATGCTA
TGGCTATTGCCAAAGATTATGCTGATTATGTTTGTAAAGCTAATGGCGGTGCTGGTGCAGTAAGAGAATTTTGTGAATAT
CTAATCAAACAATTAAATCTCTATGACAATATTGTGGATGATTATATTCAAAGTGGCGGAGTGAGATAA

Upstream 100 bases:

>100_bases
CTACAAATAGTTTATTCTTTTGTTTTTAATATATTTTAGTCTTTTTATCATTTGTGATAATATCTTTGGTTGAAGTTAAT
AATTCTTTTTAAACTTAATA

Downstream 100 bases:

>100_bases
ATAAGTAATGAAGTTTTTTACAAAATACTCCTTATTTGCGAATGTACTCTCTATAATTGTAATTATTTTTTCAATTCTGT
ATATAAGCTATAATGCTCTA

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKINHSRNSINIKLLILDVDGVLTDGKIIVTNDGDELKNFDVKDGLGIVLMQKLGIKVAIITGKQSKIVDDRFKNLGLDP
EDILQGQKNKLKAYEFLKSKYKLNDSDIAYMGDDLPDIILMNKVAISAAPADAMAIAKDYADYVCKANGGAGAVREFCEY
LIKQLNLYDNIVDDYIQSGGVR

Sequences:

>Translated_182_residues
MKINHSRNSINIKLLILDVDGVLTDGKIIVTNDGDELKNFDVKDGLGIVLMQKLGIKVAIITGKQSKIVDDRFKNLGLDP
EDILQGQKNKLKAYEFLKSKYKLNDSDIAYMGDDLPDIILMNKVAISAAPADAMAIAKDYADYVCKANGGAGAVREFCEY
LIKQLNLYDNIVDDYIQSGGVR
>Mature_182_residues
MKINHSRNSINIKLLILDVDGVLTDGKIIVTNDGDELKNFDVKDGLGIVLMQKLGIKVAIITGKQSKIVDDRFKNLGLDP
EDILQGQKNKLKAYEFLKSKYKLNDSDIAYMGDDLPDIILMNKVAISAAPADAMAIAKDYADYVCKANGGAGAVREFCEY
LIKQLNLYDNIVDDYIQSGGVR

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=36.1842105263158, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI2367202, Length=152, Percent_Identity=50, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20073; Mature: 20073

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINHSRNSINIKLLILDVDGVLTDGKIIVTNDGDELKNFDVKDGLGIVLMQKLGIKVAI
CCCCCCCCEEEEEEEEEECCCEEECCEEEEECCCCHHCCCCCCCCCHHHHHHHCCEEEEE
ITGKQSKIVDDRFKNLGLDPEDILQGQKNKLKAYEFLKSKYKLNDSDIAYMGDDLPDIIL
EECCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
MNKVAISAAPADAMAIAKDYADYVCKANGGAGAVREFCEYLIKQLNLYDNIVDDYIQSGG
HHHHHEECCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VR
CC
>Mature Secondary Structure
MKINHSRNSINIKLLILDVDGVLTDGKIIVTNDGDELKNFDVKDGLGIVLMQKLGIKVAI
CCCCCCCCEEEEEEEEEECCCEEECCEEEEECCCCHHCCCCCCCCCHHHHHHHCCEEEEE
ITGKQSKIVDDRFKNLGLDPEDILQGQKNKLKAYEFLKSKYKLNDSDIAYMGDDLPDIIL
EECCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
MNKVAISAAPADAMAIAKDYADYVCKANGGAGAVREFCEYLIKQLNLYDNIVDDYIQSGG
HHHHHEECCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]