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The map label for this gene is ppa [H]

Identifier: 89256396

GI number: 89256396

Start: 1015107

End: 1015628

Strand: Direct

Name: ppa [H]

Synonym: FTL_1061

Alternate gene names: 89256396

Gene position: 1015107-1015628 (Clockwise)

Preceding gene: 89256389

Following gene: 89256397

Centisome position: 53.54

GC content: 32.18

Gene sequence:

>522_bases
ATGCTAAATAATATACCTTGTGGAAAAGATATTCCTAATGATTTTAATGTTGTAATAGAAATACCTCAAGATAGCGATCC
TATAAAATATGAATTTGATAAAGATAGCAACATGATAGTTGTTGATAGGTTTATGTCATCTACTATGAGATATCCTTGTA
ATTATGGCTTTGTGCCAAATACTATTTATGATGATGGAGATCCTATCGATGTATTGGTTTTAGCGCCATATCCTTTAGCA
GTTGGTTGTGTAATAAACTGTAGAGCAGTTGGTGTGTTTAAAATGGAAGATGATGGTGGTGTTGATGCTAAAGTTATTGC
AGTACCTAGCTCTAAGTTAACTAAAGAATATGATCATATTAACGATGTTGATGATTTGCCGGTATCTTTAAAGCAAAAAA
TTGAGCATTTCTTTACACATTACAAAGATTTAGACTCAGGTAAGTGGGTTAAAGTAGAAGGCTGGGATAATGCTGCCTTT
GCTAGAAAAGAAATCGAAAAATCTGTAAAAAACTACAAATAG

Upstream 100 bases:

>100_bases
ATTTTAATATTTATGTGTTATAAATACAAAGGTTTTTGTGATAGACTCTTTGTCAGTGTCTTAGGCGTTAATAATTAGCA
AAAATATAGGAGAAATCAAT

Downstream 100 bases:

>100_bases
TTTATTCTTTTGTTTTTAATATATTTTAGTCTTTTTATCATTTGTGATAATATCTTTGGTTGAAGTTAATAATTCTTTTT
AAACTTAATAATGAAAATAA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MLNNIPCGKDIPNDFNVVIEIPQDSDPIKYEFDKDSNMIVVDRFMSSTMRYPCNYGFVPNTIYDDGDPIDVLVLAPYPLA
VGCVINCRAVGVFKMEDDGGVDAKVIAVPSSKLTKEYDHINDVDDLPVSLKQKIEHFFTHYKDLDSGKWVKVEGWDNAAF
ARKEIEKSVKNYK

Sequences:

>Translated_173_residues
MLNNIPCGKDIPNDFNVVIEIPQDSDPIKYEFDKDSNMIVVDRFMSSTMRYPCNYGFVPNTIYDDGDPIDVLVLAPYPLA
VGCVINCRAVGVFKMEDDGGVDAKVIAVPSSKLTKEYDHINDVDDLPVSLKQKIEHFFTHYKDLDSGKWVKVEGWDNAAF
ARKEIEKSVKNYK
>Mature_173_residues
MLNNIPCGKDIPNDFNVVIEIPQDSDPIKYEFDKDSNMIVVDRFMSSTMRYPCNYGFVPNTIYDDGDPIDVLVLAPYPLA
VGCVINCRAVGVFKMEDDGGVDAKVIAVPSSKLTKEYDHINDVDDLPVSLKQKIEHFFTHYKDLDSGKWVKVEGWDNAAF
ARKEIEKSVKNYK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=62.7906976744186, Blast_Score=229, Evalue=7e-62,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19588; Mature: 19588

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNIPCGKDIPNDFNVVIEIPQDSDPIKYEFDKDSNMIVVDRFMSSTMRYPCNYGFVPN
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCEEEEEEHHHHHHCCCCCCCCCCC
TIYDDGDPIDVLVLAPYPLAVGCVINCRAVGVFKMEDDGGVDAKVIAVPSSKLTKEYDHI
CCCCCCCCEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHCC
NDVDDLPVSLKQKIEHFFTHYKDLDSGKWVKVEGWDNAAFARKEIEKSVKNYK
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNNIPCGKDIPNDFNVVIEIPQDSDPIKYEFDKDSNMIVVDRFMSSTMRYPCNYGFVPN
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCEEEEEEHHHHHHCCCCCCCCCCC
TIYDDGDPIDVLVLAPYPLAVGCVINCRAVGVFKMEDDGGVDAKVIAVPSSKLTKEYDHI
CCCCCCCCEEEEEECCCCEEEEEEEEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHCC
NDVDDLPVSLKQKIEHFFTHYKDLDSGKWVKVEGWDNAAFARKEIEKSVKNYK
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]