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The map label for this gene is hdc [H]

Identifier: 89256289

GI number: 89256289

Start: 908654

End: 909790

Strand: Reverse

Name: hdc [H]

Synonym: FTL_0938

Alternate gene names: 89256289

Gene position: 909790-908654 (Counterclockwise)

Preceding gene: 89256290

Following gene: 89256287

Centisome position: 47.98

GC content: 28.41

Gene sequence:

>1137_bases
ATGAAAAATATTGAAGATTTAAAACTTAGGCTAAGACATAATAAAAAAGTTTATGTCGGTTACCCTACCGCTACAGATTT
TGATTATGATAACTGTAAAGAGCTAATATCTGAGCATTTTAATAATATTGGCAATCCATATAGTAAAGGCTCTCCTTTTA
GTACTTTAGGTCACGAAAGAGCTGTTATAAACTTTTTTCTTAAGCTATATATGTCTAATACAAATGATTCTTGGGGATAT
ATAGCAAGCTGCAGTTCAGAAGCTATACTTTATGGTGTTTGGAATGCTAGAAACTACTTTAAGGCTTATGATGTAACTTT
GGTATATAGTGATTATGCTCATTATTGCGTAAGTAAAACTGCAAATATATTAGCAATCAAAAATAAAGTTATAACTTCTC
GTAATAATGGAGAAATTGATTTAGGATCACTAGAGAGTTTCTTAAAAGAAAATTATAATAAAAATCAGGCATATATTTTT
ATTGCCACAATTGGCTCAACTATAACATCCTCAATAGATAATTATAAAGAAGCTAGAAATATTTTTAAAAAGTATACAGA
TAACTTCTATATACATCTAGATGGTGCATTTGATGGTGCTTTTCTACCGCTAAAAAACGATTATATTCTTGGAGAAGATT
TTCAATCGGTGAATATTAGTGGACATAAATTCTTAGGTAATCCGATGCCTTCAGGAATATTACTAATACAAAAAAAATAT
ATTTCTCAAAACTATGTCGAATATATTGATAATGATGATATGACGATAGGAGGCAGCAGAAATGGTTTATCAGCGGTATT
GTTATATAATAGAATTTTATCTTTAGGATCCAAAAAAGGGCTTATACAAAGATATCAAGAATGTTTAGATAAAAGTGAAA
CCTTTCTAACAATCCTAAAAAACAACAATATAAAAGCATGGAAAAATCCTCAAGCTATTACTATAGTCATAGAGGACATT
GATAAAAGAATATTTGATAAATGGCATATGCTCAAATATAAAAATCAAGCCACAATAACTTGCCTACCTAAGCTAAACAA
ACAAATGCTTATGGAATTAATTTTTGATATAAAAAATCCAGATAAAATAGATTTTTCTAATGCTAAAAAATTTGCTGAAG
ATATTAGCCCTCTTTGA

Upstream 100 bases:

>100_bases
AAAAGACTGCAGAGCAGTTTGCTAGGATAAATACTTGTCATTTGGAATTTGAAGTATTTAAAACACTAACAAAAAAATAT
AGATAATTGATTTTATTTAA

Downstream 100 bases:

>100_bases
AGTAAATCCTCCGAGCTACATTTTTAAACACATGTTTAGATATTTCATCATTATCAATGTATTTATACAAAAATTTCTGC
CAAAAATTATAATCATCATG

Product: histidine decarboxylase

Products: NA

Alternate protein names: HDC [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKNIEDLKLRLRHNKKVYVGYPTATDFDYDNCKELISEHFNNIGNPYSKGSPFSTLGHERAVINFFLKLYMSNTNDSWGY
IASCSSEAILYGVWNARNYFKAYDVTLVYSDYAHYCVSKTANILAIKNKVITSRNNGEIDLGSLESFLKENYNKNQAYIF
IATIGSTITSSIDNYKEARNIFKKYTDNFYIHLDGAFDGAFLPLKNDYILGEDFQSVNISGHKFLGNPMPSGILLIQKKY
ISQNYVEYIDNDDMTIGGSRNGLSAVLLYNRILSLGSKKGLIQRYQECLDKSETFLTILKNNNIKAWKNPQAITIVIEDI
DKRIFDKWHMLKYKNQATITCLPKLNKQMLMELIFDIKNPDKIDFSNAKKFAEDISPL

Sequences:

>Translated_378_residues
MKNIEDLKLRLRHNKKVYVGYPTATDFDYDNCKELISEHFNNIGNPYSKGSPFSTLGHERAVINFFLKLYMSNTNDSWGY
IASCSSEAILYGVWNARNYFKAYDVTLVYSDYAHYCVSKTANILAIKNKVITSRNNGEIDLGSLESFLKENYNKNQAYIF
IATIGSTITSSIDNYKEARNIFKKYTDNFYIHLDGAFDGAFLPLKNDYILGEDFQSVNISGHKFLGNPMPSGILLIQKKY
ISQNYVEYIDNDDMTIGGSRNGLSAVLLYNRILSLGSKKGLIQRYQECLDKSETFLTILKNNNIKAWKNPQAITIVIEDI
DKRIFDKWHMLKYKNQATITCLPKLNKQMLMELIFDIKNPDKIDFSNAKKFAEDISPL
>Mature_378_residues
MKNIEDLKLRLRHNKKVYVGYPTATDFDYDNCKELISEHFNNIGNPYSKGSPFSTLGHERAVINFFLKLYMSNTNDSWGY
IASCSSEAILYGVWNARNYFKAYDVTLVYSDYAHYCVSKTANILAIKNKVITSRNNGEIDLGSLESFLKENYNKNQAYIF
IATIGSTITSSIDNYKEARNIFKKYTDNFYIHLDGAFDGAFLPLKNDYILGEDFQSVNISGHKFLGNPMPSGILLIQKKY
ISQNYVEYIDNDDMTIGGSRNGLSAVLLYNRILSLGSKKGLIQRYQECLDKSETFLTILKNNNIKAWKNPQAITIVIEDI
DKRIFDKWHMLKYKNQATITCLPKLNKQMLMELIFDIKNPDKIDFSNAKKFAEDISPL

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.22 [H]

Molecular weight: Translated: 43391; Mature: 43391

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIEDLKLRLRHNKKVYVGYPTATDFDYDNCKELISEHFNNIGNPYSKGSPFSTLGHER
CCCHHHHHHHEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCHHH
AVINFFLKLYMSNTNDSWGYIASCSSEAILYGVWNARNYFKAYDVTLVYSDYAHYCVSKT
HHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEEEEEECCHHHHHHHCC
ANILAIKNKVITSRNNGEIDLGSLESFLKENYNKNQAYIFIATIGSTITSSIDNYKEARN
CCEEEEECEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
IFKKYTDNFYIHLDGAFDGAFLPLKNDYILGEDFQSVNISGHKFLGNPMPSGILLIQKKY
HHHHHCCCEEEEEECCCCCEEEECCCCEEECCCCCCCCCCCCEECCCCCCCCEEEEEHHH
ISQNYVEYIDNDDMTIGGSRNGLSAVLLYNRILSLGSKKGLIQRYQECLDKSETFLTILK
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEE
NNNIKAWKNPQAITIVIEDIDKRIFDKWHMLKYKNQATITCLPKLNKQMLMELIFDIKNP
CCCEEEECCCCEEEEEEEHHHHHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHCCCC
DKIDFSNAKKFAEDISPL
CCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKNIEDLKLRLRHNKKVYVGYPTATDFDYDNCKELISEHFNNIGNPYSKGSPFSTLGHER
CCCHHHHHHHEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCHHH
AVINFFLKLYMSNTNDSWGYIASCSSEAILYGVWNARNYFKAYDVTLVYSDYAHYCVSKT
HHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEEEEEECCHHHHHHHCC
ANILAIKNKVITSRNNGEIDLGSLESFLKENYNKNQAYIFIATIGSTITSSIDNYKEARN
CCEEEEECEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHH
IFKKYTDNFYIHLDGAFDGAFLPLKNDYILGEDFQSVNISGHKFLGNPMPSGILLIQKKY
HHHHHCCCEEEEEECCCCCEEEECCCCEEECCCCCCCCCCCCEECCCCCCCCEEEEEHHH
ISQNYVEYIDNDDMTIGGSRNGLSAVLLYNRILSLGSKKGLIQRYQECLDKSETFLTILK
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEE
NNNIKAWKNPQAITIVIEDIDKRIFDKWHMLKYKNQATITCLPKLNKQMLMELIFDIKNP
CCCEEEECCCCEEEEEEEHHHHHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHCCCC
DKIDFSNAKKFAEDISPL
CCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]