Click here to switch to the map view.

The map label for this gene is 89256236

Identifier: 89256236

GI number: 89256236

Start: 856270

End: 857334

Strand: Direct

Name: 89256236

Synonym: FTL_0878

Alternate gene names: NA

Gene position: 856270-857334 (Clockwise)

Preceding gene: 89256235

Following gene: 89256238

Centisome position: 45.16

GC content: 32.49

Gene sequence:

>1065_bases
ATGACAAAAAAAACATCTAAGCAAAAAGATACTAAAAAACAAACCACTAAGAAGCCGATAAATTATATAAAAATATTTAT
ACTACTAGCTTTAACTATTGGTGGCGGATTTTCCGGTATTTTTTTTGACAAGTTTGATTTAAAAGAAAAATTTATAAACT
TTAGGCATGCTGTATATAACTATTTCACTAGTGAACCAATAAAGCACTATACCACCAAAGATAACGAGAATATTATTGCT
AGATTTTTTTCACAAAGTGATGAGGGGAAAAAACAACAGCAACAATCAAATGAGTTTGACAACCTCAAGCAGTATCCACC
AGTTAGAACTCTACCAGCAGTTACTGATTATTGCCATGGTTTTCTAGCTTATGGTAATCCTAGTTATGGTGTAACTGATG
GTTTAGGTCAAGCAAATCTTTATCTATGTCGTGATGGTTATGTTGTTGGTTATAACTATCAAACTAAAGAGGCAAGCTGG
GTAGCATTTAATTTGACAAAGTCAAAAGTAGCAAATCATCTTAAACGTGATGATAGATTTAAAGAAGACAGTGATGTGCC
ATTTGTCTATAGAGCGACATTAGATGATTATTCTCGTTCTGGTTATGACAGAGGACATCTAGCTTCATATGCATCAATGG
ACTTTAGCAAAAAATCTGCAGATCAATCATTCTTATTATCAAATATGTCACCACAAAAAGCAGAGCTTAATAGGCAAGGC
TGGGAGAGGCTAGAAACGGATGAGCGAATCTGGGCAAATATGTATGATAGTATATATGTCTACACAGGACCAATATATAA
AAAACAAAAAATTCATAAAACTATAGGTGATAATAAGATAGCTGTACCTGATTATTTTTTTAAGATAATTTATGTACCTT
CTAAAAATCAAGCAATAGCATTTGTAATGCCTAATGCAAGAGTTGAAAAGACTAAGATTGCTAACTATAGGGTTTCTATA
AAAGATATTGAGCAATGTACCGGATTGCATTTTTTGACTAATATTTCAAATAGAGATGCTGTGATAAATAGCGTCTCCTC
AATGTGGCGTACCGCTTATTTATAA

Upstream 100 bases:

>100_bases
TAGTATTATCTTTATTATAAAAACAGTAAGAAATTCTTATTTTAAGAAAAAAGTTAATAGTTTTTAACTTTTTACAAAAT
AAACTAAAAAGTATTTAAGC

Downstream 100 bases:

>100_bases
GTGTTAGTCAGATCATTAGCTATTAATTTAGCTGCTTGTTGAATAATTTCTTCATTACTTGGTGCATTTTTATCATTAGG
GTTAGTATATAAAATTCCTA

Product: DNA/RNA endonuclease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTKKTSKQKDTKKQTTKKPINYIKIFILLALTIGGGFSGIFFDKFDLKEKFINFRHAVYNYFTSEPIKHYTTKDNENIIA
RFFSQSDEGKKQQQQSNEFDNLKQYPPVRTLPAVTDYCHGFLAYGNPSYGVTDGLGQANLYLCRDGYVVGYNYQTKEASW
VAFNLTKSKVANHLKRDDRFKEDSDVPFVYRATLDDYSRSGYDRGHLASYASMDFSKKSADQSFLLSNMSPQKAELNRQG
WERLETDERIWANMYDSIYVYTGPIYKKQKIHKTIGDNKIAVPDYFFKIIYVPSKNQAIAFVMPNARVEKTKIANYRVSI
KDIEQCTGLHFLTNISNRDAVINSVSSMWRTAYL

Sequences:

>Translated_354_residues
MTKKTSKQKDTKKQTTKKPINYIKIFILLALTIGGGFSGIFFDKFDLKEKFINFRHAVYNYFTSEPIKHYTTKDNENIIA
RFFSQSDEGKKQQQQSNEFDNLKQYPPVRTLPAVTDYCHGFLAYGNPSYGVTDGLGQANLYLCRDGYVVGYNYQTKEASW
VAFNLTKSKVANHLKRDDRFKEDSDVPFVYRATLDDYSRSGYDRGHLASYASMDFSKKSADQSFLLSNMSPQKAELNRQG
WERLETDERIWANMYDSIYVYTGPIYKKQKIHKTIGDNKIAVPDYFFKIIYVPSKNQAIAFVMPNARVEKTKIANYRVSI
KDIEQCTGLHFLTNISNRDAVINSVSSMWRTAYL
>Mature_353_residues
TKKTSKQKDTKKQTTKKPINYIKIFILLALTIGGGFSGIFFDKFDLKEKFINFRHAVYNYFTSEPIKHYTTKDNENIIAR
FFSQSDEGKKQQQQSNEFDNLKQYPPVRTLPAVTDYCHGFLAYGNPSYGVTDGLGQANLYLCRDGYVVGYNYQTKEASWV
AFNLTKSKVANHLKRDDRFKEDSDVPFVYRATLDDYSRSGYDRGHLASYASMDFSKKSADQSFLLSNMSPQKAELNRQGW
ERLETDERIWANMYDSIYVYTGPIYKKQKIHKTIGDNKIAVPDYFFKIIYVPSKNQAIAFVMPNARVEKTKIANYRVSIK
DIEQCTGLHFLTNISNRDAVINSVSSMWRTAYL

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI53759134, Length=232, Percent_Identity=35.3448275862069, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI224451073, Length=222, Percent_Identity=28.8288288288288, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI224451075, Length=185, Percent_Identity=30.2702702702703, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17505967, Length=212, Percent_Identity=34.9056603773585, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322253, Length=252, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20129899, Length=208, Percent_Identity=33.6538461538462, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24581065, Length=228, Percent_Identity=31.5789473684211, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28571642, Length=229, Percent_Identity=27.5109170305677, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: 3.1.30.-

Molecular weight: Translated: 40934; Mature: 40803

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKTSKQKDTKKQTTKKPINYIKIFILLALTIGGGFSGIFFDKFDLKEKFINFRHAVYN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHH
YFTSEPIKHYTTKDNENIIARFFSQSDEGKKQQQQSNEFDNLKQYPPVRTLPAVTDYCHG
HHHCCCHHHCCCCCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHCC
FLAYGNPSYGVTDGLGQANLYLCRDGYVVGYNYQTKEASWVAFNLTKSKVANHLKRDDRF
EEEECCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHCCC
KEDSDVPFVYRATLDDYSRSGYDRGHLASYASMDFSKKSADQSFLLSNMSPQKAELNRQG
CCCCCCCEEEEECHHHHHHCCCCCCHHHHHHHCCCCHHCCCHHHHHCCCCCHHHHHHHHH
WERLETDERIWANMYDSIYVYTGPIYKKQKIHKTIGDNKIAVPDYFFKIIYVPSKNQAIA
HHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCEECCCEEEEEEEECCCCCEEE
FVMPNARVEKTKIANYRVSIKDIEQCTGLHFLTNISNRDAVINSVSSMWRTAYL
EEECCCCCCCEEECEEEEEHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKKTSKQKDTKKQTTKKPINYIKIFILLALTIGGGFSGIFFDKFDLKEKFINFRHAVYN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHH
YFTSEPIKHYTTKDNENIIARFFSQSDEGKKQQQQSNEFDNLKQYPPVRTLPAVTDYCHG
HHHCCCHHHCCCCCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHCC
FLAYGNPSYGVTDGLGQANLYLCRDGYVVGYNYQTKEASWVAFNLTKSKVANHLKRDDRF
EEEECCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHCCC
KEDSDVPFVYRATLDDYSRSGYDRGHLASYASMDFSKKSADQSFLLSNMSPQKAELNRQG
CCCCCCCEEEEECHHHHHHCCCCCCHHHHHHHCCCCHHCCCHHHHHCCCCCHHHHHHHHH
WERLETDERIWANMYDSIYVYTGPIYKKQKIHKTIGDNKIAVPDYFFKIIYVPSKNQAIA
HHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCEECCCEEEEEEEECCCCCEEE
FVMPNARVEKTKIANYRVSIKDIEQCTGLHFLTNISNRDAVINSVSSMWRTAYL
EEECCCCCCCEEECEEEEEHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]