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The map label for this gene is can [H]

Identifier: 89256216

GI number: 89256216

Start: 836941

End: 837627

Strand: Direct

Name: can [H]

Synonym: FTL_0856

Alternate gene names: 89256216

Gene position: 836941-837627 (Clockwise)

Preceding gene: 89256215

Following gene: 89256221

Centisome position: 44.14

GC content: 34.93

Gene sequence:

>687_bases
ATGAGTGATATTTCTGAGTTGATAAAAGGCAATAGAGCATGGGCTGAAGAGATCAAAAAAACAAATCCAGGTTTTTTTGA
AACTTTATCTAAAGGTCAGTCTCCAGAATACCTTTGGATAGGTTGTTCAGATAGTCGAGTACCTGCAAACCAAATTTGTG
GTTTGATTCCAGGTGAGGTTTTTGTCCATCGTAATGTTGCAAACGTTGTTTCACTTACAGATTTAAACTGTTTGTCAGTG
TTACAGTTTGCTATTGAAGTCTTAAAGATTAAGAAAATAATAGTATGTGGTCACTATGCTTGTGGTGGTGTTGAGACTGT
TGTCAAAGATAAGAGCTATGGTCTAATTGATAACTGGCTAACGTCTATCCATGAAGTTAAAGAGCAAAACAAACAGTTTA
TTGAAGAGTCATTATCTTGTTACAAAGATAATCAAGAAGAATATATGAAGAAAAAAGTAGATATGATGTGTGAGCTAAAT
GCACTTCATCAAGCACTAAATCTTTGTAAAACTACAGTTGTTAAAAATGCGTGGGCAAAAGGGCTTACCTTTACTATACA
TGCAGCTATATACGGTATTGGCGATGGTAAGCTTTATGAAATTGGTGGTGGTGTAGGCTCAAGAGCAGAGATGGATACTA
CTTATGCTCAAGCTATTAAAGACATCAAATCTAGATATTGTAGATAA

Upstream 100 bases:

>100_bases
GTTTCATTACAAGGCGAAGTAACGATATAACTTAAATATAAATAGTAAAAAGCTTATACGTATAGCTAGCTAATACTAAT
AATAATTTCAAGGAGATAAA

Downstream 100 bases:

>100_bases
TCTAATTCTGTTGATTTTTTATATTTGTCAAAATAACTTATATTATATAAGTAATATATGACTATAAACATATAAATTCA
TAAATGAATGAAATTATAGT

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSDISELIKGNRAWAEEIKKTNPGFFETLSKGQSPEYLWIGCSDSRVPANQICGLIPGEVFVHRNVANVVSLTDLNCLSV
LQFAIEVLKIKKIIVCGHYACGGVETVVKDKSYGLIDNWLTSIHEVKEQNKQFIEESLSCYKDNQEEYMKKKVDMMCELN
ALHQALNLCKTTVVKNAWAKGLTFTIHAAIYGIGDGKLYEIGGGVGSRAEMDTTYAQAIKDIKSRYCR

Sequences:

>Translated_228_residues
MSDISELIKGNRAWAEEIKKTNPGFFETLSKGQSPEYLWIGCSDSRVPANQICGLIPGEVFVHRNVANVVSLTDLNCLSV
LQFAIEVLKIKKIIVCGHYACGGVETVVKDKSYGLIDNWLTSIHEVKEQNKQFIEESLSCYKDNQEEYMKKKVDMMCELN
ALHQALNLCKTTVVKNAWAKGLTFTIHAAIYGIGDGKLYEIGGGVGSRAEMDTTYAQAIKDIKSRYCR
>Mature_227_residues
SDISELIKGNRAWAEEIKKTNPGFFETLSKGQSPEYLWIGCSDSRVPANQICGLIPGEVFVHRNVANVVSLTDLNCLSVL
QFAIEVLKIKKIIVCGHYACGGVETVVKDKSYGLIDNWLTSIHEVKEQNKQFIEESLSCYKDNQEEYMKKKVDMMCELNA
LHQALNLCKTTVVKNAWAKGLTFTIHAAIYGIGDGKLYEIGGGVGSRAEMDTTYAQAIKDIKSRYCR

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=227, Percent_Identity=42.7312775330396, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI1786534, Length=204, Percent_Identity=25, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324292, Length=203, Percent_Identity=30.0492610837438, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25439; Mature: 25307

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDISELIKGNRAWAEEIKKTNPGFFETLSKGQSPEYLWIGCSDSRVPANQICGLIPGEV
CCCHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCHH
FVHRNVANVVSLTDLNCLSVLQFAIEVLKIKKIIVCGHYACGGVETVVKDKSYGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCHHHHHH
TSIHEVKEQNKQFIEESLSCYKDNQEEYMKKKVDMMCELNALHQALNLCKTTVVKNAWAK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTFTIHAAIYGIGDGKLYEIGGGVGSRAEMDTTYAQAIKDIKSRYCR
CCCEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDISELIKGNRAWAEEIKKTNPGFFETLSKGQSPEYLWIGCSDSRVPANQICGLIPGEV
CCHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCHH
FVHRNVANVVSLTDLNCLSVLQFAIEVLKIKKIIVCGHYACGGVETVVKDKSYGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCHHHHHH
TSIHEVKEQNKQFIEESLSCYKDNQEEYMKKKVDMMCELNALHQALNLCKTTVVKNAWAK
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTFTIHAAIYGIGDGKLYEIGGGVGSRAEMDTTYAQAIKDIKSRYCR
CCCEEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]