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The map label for this gene is 89256045

Identifier: 89256045

GI number: 89256045

Start: 637263

End: 638012

Strand: Direct

Name: 89256045

Synonym: FTL_0654

Alternate gene names: NA

Gene position: 637263-638012 (Clockwise)

Preceding gene: 89256044

Following gene: 89256046

Centisome position: 33.61

GC content: 29.07

Gene sequence:

>750_bases
ATGAAAATACTAGTTTGTCGCCCTCATAATGATGCTGTCAATTTAACAGAAAAACTCTGTGCAAATGGTCTTTTAGCGGT
AAGTTTACCAACTATCAAAATTTGTTATCAAAAAATTACTGAGAGTGTTCTTGACTATACAAGTCTAGTTTTTACTAGTA
AATATGCTGTTGAAAGCTTGTTTAGTCAATATCCAATCGATTTGTTTAAAAATAAAAAGATCTATAGTGTCGGTGCCAGT
ACTGCTGCTATATTAGAAAAATACCAATTAGCTGCAATATATCCAGTTAGACATGGCTCACAAGAACTTTTAGATATCAT
ATTAAATCAAGATATTTCTAAAGAAAAATTTGCGATTATTTCTGGTGTCTCTGGTAATGATCTTTTGCTTGAAGAGTTAT
CAAAATTAACACACTGTCATAAATTTGAGACGTATTTACGAGTTTTTATAGATCTTTATGAGTTGTTAGATACTTATAAT
AAACTTTTTTTACATAATCAGCCGGATATTATAATTGCTACAAGTCTTGATGTTTTTAAATCATTAAATAGAATTTTCGA
AAAAATAACTACTCCAAAGGCTGCAACAATTACCATAACAAGCCTAAAAATGCTAAAATTTGTTAATCAACAAGGCTTTA
AAAATACCTTAAAACTTGAGAAACTAGATAATAGTTATATCTGTCAAAGAATACTAGAATTTACAGAGGCAAAAGATGTC
AATAGAAAAAAACACCCAGCAACAAAGTAG

Upstream 100 bases:

>100_bases
TAAGCAGATAGGTTTTGGTAATAATTTAAGTACAACACGTGCCAATGGCTTAAAATCAATGCTTGATTATATATATGCTA
CAGCTAAACAAAATCAGTAA

Downstream 100 bases:

>100_bases
CACTCAGGATAATCCAGCTAAAAAAACAGCAAGAGTAGATAATAAATCTTCAATAGGAGGGGTATTTGCTAAGATTACCT
TAGCGGTATCTATAGCTGCA

Product: uroporphyrinogen III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKILVCRPHNDAVNLTEKLCANGLLAVSLPTIKICYQKITESVLDYTSLVFTSKYAVESLFSQYPIDLFKNKKIYSVGAS
TAAILEKYQLAAIYPVRHGSQELLDIILNQDISKEKFAIISGVSGNDLLLEELSKLTHCHKFETYLRVFIDLYELLDTYN
KLFLHNQPDIIIATSLDVFKSLNRIFEKITTPKAATITITSLKMLKFVNQQGFKNTLKLEKLDNSYICQRILEFTEAKDV
NRKKHPATK

Sequences:

>Translated_249_residues
MKILVCRPHNDAVNLTEKLCANGLLAVSLPTIKICYQKITESVLDYTSLVFTSKYAVESLFSQYPIDLFKNKKIYSVGAS
TAAILEKYQLAAIYPVRHGSQELLDIILNQDISKEKFAIISGVSGNDLLLEELSKLTHCHKFETYLRVFIDLYELLDTYN
KLFLHNQPDIIIATSLDVFKSLNRIFEKITTPKAATITITSLKMLKFVNQQGFKNTLKLEKLDNSYICQRILEFTEAKDV
NRKKHPATK
>Mature_249_residues
MKILVCRPHNDAVNLTEKLCANGLLAVSLPTIKICYQKITESVLDYTSLVFTSKYAVESLFSQYPIDLFKNKKIYSVGAS
TAAILEKYQLAAIYPVRHGSQELLDIILNQDISKEKFAIISGVSGNDLLLEELSKLTHCHKFETYLRVFIDLYELLDTYN
KLFLHNQPDIIIATSLDVFKSLNRIFEKITTPKAATITITSLKMLKFVNQQGFKNTLKLEKLDNSYICQRILEFTEAKDV
NRKKHPATK

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 28403; Mature: 28403

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVCRPHNDAVNLTEKLCANGLLAVSLPTIKICYQKITESVLDYTSLVFTSKYAVESL
CEEEEECCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSQYPIDLFKNKKIYSVGASTAAILEKYQLAAIYPVRHGSQELLDIILNQDISKEKFAII
HHHCCHHHHCCCEEEEECCHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCCCCCCEEEE
SGVSGNDLLLEELSKLTHCHKFETYLRVFIDLYELLDTYNKLFLHNQPDIIIATSLDVFK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHH
SLNRIFEKITTPKAATITITSLKMLKFVNQQGFKNTLKLEKLDNSYICQRILEFTEAKDV
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCC
NRKKHPATK
CCCCCCCCC
>Mature Secondary Structure
MKILVCRPHNDAVNLTEKLCANGLLAVSLPTIKICYQKITESVLDYTSLVFTSKYAVESL
CEEEEECCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSQYPIDLFKNKKIYSVGASTAAILEKYQLAAIYPVRHGSQELLDIILNQDISKEKFAII
HHHCCHHHHCCCEEEEECCHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCCCCCCCEEEE
SGVSGNDLLLEELSKLTHCHKFETYLRVFIDLYELLDTYNKLFLHNQPDIIIATSLDVFK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHH
SLNRIFEKITTPKAATITITSLKMLKFVNQQGFKNTLKLEKLDNSYICQRILEFTEAKDV
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCC
NRKKHPATK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA