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The map label for this gene is recG [H]

Identifier: 89255931

GI number: 89255931

Start: 502369

End: 504408

Strand: Direct

Name: recG [H]

Synonym: FTL_0524

Alternate gene names: 89255931

Gene position: 502369-504408 (Clockwise)

Preceding gene: 89255918

Following gene: 89255932

Centisome position: 26.5

GC content: 34.22

Gene sequence:

>2040_bases
ATGAGGTTTGTTGATTTTAATGGTGTCGGTGAGGCAACTATCAAGGCATTAGCTAAATATAATATACATGACCCAAATGA
TCTATTAACTATTTTTCCAAAAGACTACAAAGATACACGGGTCATAACACCTATTAATCATCTTGTTGCTGGTAAGAGAA
GTTTGATCCAAGGGAGAGTTACTAATCTTACATATAAAAAATTTGGTAAAAAATTTTTGCGTTTTAATATTAATGATAAT
ACAGGTTTCTGTAGCGTGATATTATTTAAATTTTACCCTAATCAGCTAGCCATTCTTGAGAAGTCTGAGTATGTGCGTTG
TTATGGTAAGGTTGAATTCTCTCTGAGCCCACAAATGGTTCATCCAGAGTGGGCTACTGTTAATAATGGGGAATGTACTT
TAAAACATGGGTTTTCAGCAGTTTATCGCCTTAAAAAAATTCCTGATAGATTAATTTCTAAGATGATTTTGAAAATGTTA
CAGGATAATAGGGTTGAAAATATTATTCCTTCACAGCTGTTACGTAGATTTAATTTGATTAGTTTTTGTGATGCTTTGTA
TTATGTCCATGCTTTGACAAATTTTATTGATGAAAAATATTTAAGCATAGCGAGGTTCTCGATTAAATTTGAAGAGATGC
TTGCTTATAAACTAGCTGAGCAAAATATTTATAAAAATACTGTAAAAGCACAAGCCCCACAACTATTTTTAACGAAAATT
CAGCAAAACGAATTTTATGAAAAGTTACCATATCAACTAACTAATGCTCAGCAGCGAGCGATCACAGAAATTCTTGATGA
TATTAAAAAGTCTAATGCGATGAATAGACTTCTGCAAGGTGATGTTGGGGCGGGTAAGACTATTGTTGCGACTATCGCAG
CATACGCCGCAGTTAAATCTGGTTATCAAGTTGCTATGATGGCGCCTACTGAAATTTTAGCTGAGCAACATTTTAGTTTT
CTTTCTCAGTATTTGGCTAGTTTTGATATAAAAGTCATCCCATTATTAGGTAAATTATCAGCAAAACAAACTCGTGAAAG
TTTAGACAAAATTAAAGATCAAAAAGATTGTGTGGTTGTCGGTACTCATGCAATTTTTCAAGAGCGAGTCGAATATTGTA
ATCTAGGTCTAGTAATTGTAGATGAACAACATAGATTTGGTGTTGAGCAGCGCTTAGCACTGGTAAGTAAGTCATCATCA
AATTTTAGCGATCTAACGCCACATCAGCTAATAATTTCAGCAACACCTATTCCAAGAACTTTAGCGATGACTTTATATGG
TAATCTCAAACTATCGATTTTAGATGAGTTACCACCTAAGCGTAAACCAATAATTACAACTGTGTTAAATAGAGCTAAAA
AACAAAATTTGATCGAAAAAGTTAAACAAGCGGTATTACGTGGCGAACAAGTATATTGGGTATGTCCGTTAGTCGAGGAG
TCTGAAAACATGGACTTTTTGCAAGATGTCAAAACATTATATCAAGAGTTACTTGAGGCTTTAGGTAAAGAAAATGTTGG
TCTTGTCTATGGTAGTATGAAGTCTAAGGATAAAATCGAACAAATGGCTGCATTTAAAGCTAAAAAATACGCAGTACTTG
TGGCAACAACTGTTATAGAAGTCGGTGTTGATGTGCCAAACGCAACTATTATGATAATAGATAATGCTGAAAGACTTGGT
ATATCACAGCTTCATCAGCTTCGTGGTAGGGTTGGTAGAGGGGCTAAAGAAAGCTATTGTATTCTTCTATATAGTGATAA
AATTAGCGAGGTTGGCAAGAGGAGACTATCATTGGTAAGAGAGTCTCAAGATGGTTTTTATTTAGCTGAGAAAGATCTAG
AGATTCGCGGTGCTGGAGATATCCTTGGTAAGGAGCAATCAGGAGTATCAACCTTTAAAACTTTTGACATTAATGAGTAT
TATGATAATTATGATAAAGTTGTAGAGTTTGCTGATATGTTAGATAAACATTATCCAGAGTTAGTTGATAAACTAATCCA
ACGCTGGTTTGATAGAAGAGTAAATTATGTGGAGGTTTAG

Upstream 100 bases:

>100_bases
TTTAGAATTTAGCAATAAATGTTTGGTTTGGCAATTCAATTATCTATTTAAACACTAAAATGCTAAAATTTTAATTAGTT
TATTTATTGTTGATAATTTT

Downstream 100 bases:

>100_bases
AAGATGATTTTACTGAGTGTGGTATCGATACTTATAGCCTTGTTAGTTATCCTTGGTGTGGCTAAAATACTATATAATTC
TAGTTTTAGAAAAAATAAGC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MRFVDFNGVGEATIKALAKYNIHDPNDLLTIFPKDYKDTRVITPINHLVAGKRSLIQGRVTNLTYKKFGKKFLRFNINDN
TGFCSVILFKFYPNQLAILEKSEYVRCYGKVEFSLSPQMVHPEWATVNNGECTLKHGFSAVYRLKKIPDRLISKMILKML
QDNRVENIIPSQLLRRFNLISFCDALYYVHALTNFIDEKYLSIARFSIKFEEMLAYKLAEQNIYKNTVKAQAPQLFLTKI
QQNEFYEKLPYQLTNAQQRAITEILDDIKKSNAMNRLLQGDVGAGKTIVATIAAYAAVKSGYQVAMMAPTEILAEQHFSF
LSQYLASFDIKVIPLLGKLSAKQTRESLDKIKDQKDCVVVGTHAIFQERVEYCNLGLVIVDEQHRFGVEQRLALVSKSSS
NFSDLTPHQLIISATPIPRTLAMTLYGNLKLSILDELPPKRKPIITTVLNRAKKQNLIEKVKQAVLRGEQVYWVCPLVEE
SENMDFLQDVKTLYQELLEALGKENVGLVYGSMKSKDKIEQMAAFKAKKYAVLVATTVIEVGVDVPNATIMIIDNAERLG
ISQLHQLRGRVGRGAKESYCILLYSDKISEVGKRRLSLVRESQDGFYLAEKDLEIRGAGDILGKEQSGVSTFKTFDINEY
YDNYDKVVEFADMLDKHYPELVDKLIQRWFDRRVNYVEV

Sequences:

>Translated_679_residues
MRFVDFNGVGEATIKALAKYNIHDPNDLLTIFPKDYKDTRVITPINHLVAGKRSLIQGRVTNLTYKKFGKKFLRFNINDN
TGFCSVILFKFYPNQLAILEKSEYVRCYGKVEFSLSPQMVHPEWATVNNGECTLKHGFSAVYRLKKIPDRLISKMILKML
QDNRVENIIPSQLLRRFNLISFCDALYYVHALTNFIDEKYLSIARFSIKFEEMLAYKLAEQNIYKNTVKAQAPQLFLTKI
QQNEFYEKLPYQLTNAQQRAITEILDDIKKSNAMNRLLQGDVGAGKTIVATIAAYAAVKSGYQVAMMAPTEILAEQHFSF
LSQYLASFDIKVIPLLGKLSAKQTRESLDKIKDQKDCVVVGTHAIFQERVEYCNLGLVIVDEQHRFGVEQRLALVSKSSS
NFSDLTPHQLIISATPIPRTLAMTLYGNLKLSILDELPPKRKPIITTVLNRAKKQNLIEKVKQAVLRGEQVYWVCPLVEE
SENMDFLQDVKTLYQELLEALGKENVGLVYGSMKSKDKIEQMAAFKAKKYAVLVATTVIEVGVDVPNATIMIIDNAERLG
ISQLHQLRGRVGRGAKESYCILLYSDKISEVGKRRLSLVRESQDGFYLAEKDLEIRGAGDILGKEQSGVSTFKTFDINEY
YDNYDKVVEFADMLDKHYPELVDKLIQRWFDRRVNYVEV
>Mature_679_residues
MRFVDFNGVGEATIKALAKYNIHDPNDLLTIFPKDYKDTRVITPINHLVAGKRSLIQGRVTNLTYKKFGKKFLRFNINDN
TGFCSVILFKFYPNQLAILEKSEYVRCYGKVEFSLSPQMVHPEWATVNNGECTLKHGFSAVYRLKKIPDRLISKMILKML
QDNRVENIIPSQLLRRFNLISFCDALYYVHALTNFIDEKYLSIARFSIKFEEMLAYKLAEQNIYKNTVKAQAPQLFLTKI
QQNEFYEKLPYQLTNAQQRAITEILDDIKKSNAMNRLLQGDVGAGKTIVATIAAYAAVKSGYQVAMMAPTEILAEQHFSF
LSQYLASFDIKVIPLLGKLSAKQTRESLDKIKDQKDCVVVGTHAIFQERVEYCNLGLVIVDEQHRFGVEQRLALVSKSSS
NFSDLTPHQLIISATPIPRTLAMTLYGNLKLSILDELPPKRKPIITTVLNRAKKQNLIEKVKQAVLRGEQVYWVCPLVEE
SENMDFLQDVKTLYQELLEALGKENVGLVYGSMKSKDKIEQMAAFKAKKYAVLVATTVIEVGVDVPNATIMIIDNAERLG
ISQLHQLRGRVGRGAKESYCILLYSDKISEVGKRRLSLVRESQDGFYLAEKDLEIRGAGDILGKEQSGVSTFKTFDINEY
YDNYDKVVEFADMLDKHYPELVDKLIQRWFDRRVNYVEV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=683, Percent_Identity=39.0922401171303, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1787357, Length=410, Percent_Identity=35.3658536585366, Blast_Score=247, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77550; Mature: 77550

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDFNGVGEATIKALAKYNIHDPNDLLTIFPKDYKDTRVITPINHLVAGKRSLIQGRV
CEEECCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCHHHHHHHHH
TNLTYKKFGKKFLRFNINDNTGFCSVILFKFYPNQLAILEKSEYVRCYGKVEFSLSPQMV
HCHHHHHHCCHHEEEECCCCCCHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEECCCCEE
HPEWATVNNGECTLKHGFSAVYRLKKIPDRLISKMILKMLQDNRVENIIPSQLLRRFNLI
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
SFCDALYYVHALTNFIDEKYLSIARFSIKFEEMLAYKLAEQNIYKNTVKAQAPQLFLTKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QQNEFYEKLPYQLTNAQQRAITEILDDIKKSNAMNRLLQGDVGAGKTIVATIAAYAAVKS
HHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GYQVAMMAPTEILAEQHFSFLSQYLASFDIKVIPLLGKLSAKQTRESLDKIKDQKDCVVV
CCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEE
GTHAIFQERVEYCNLGLVIVDEQHRFGVEQRLALVSKSSSNFSDLTPHQLIISATPIPRT
EHHHHHHHHHHHHCCCEEEECCHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHH
LAMTLYGNLKLSILDELPPKRKPIITTVLNRAKKQNLIEKVKQAVLRGEQVYWVCPLVEE
HHHEEECCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
SENMDFLQDVKTLYQELLEALGKENVGLVYGSMKSKDKIEQMAAFKAKKYAVLVATTVIE
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHEEHHHHHHHH
VGVDVPNATIMIIDNAERLGISQLHQLRGRVGRGAKESYCILLYSDKISEVGKRRLSLVR
HCCCCCCCEEEEEECCHHCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHH
ESQDGFYLAEKDLEIRGAGDILGKEQSGVSTFKTFDINEYYDNYDKVVEFADMLDKHYPE
CCCCCEEEEECCEEEECCCCCCCCCCCCCCCEEEECCHHHHCCHHHHHHHHHHHHHHHHH
LVDKLIQRWFDRRVNYVEV
HHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MRFVDFNGVGEATIKALAKYNIHDPNDLLTIFPKDYKDTRVITPINHLVAGKRSLIQGRV
CEEECCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEECCHHHHHHCHHHHHHHHH
TNLTYKKFGKKFLRFNINDNTGFCSVILFKFYPNQLAILEKSEYVRCYGKVEFSLSPQMV
HCHHHHHHCCHHEEEECCCCCCHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEECCCCEE
HPEWATVNNGECTLKHGFSAVYRLKKIPDRLISKMILKMLQDNRVENIIPSQLLRRFNLI
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHH
SFCDALYYVHALTNFIDEKYLSIARFSIKFEEMLAYKLAEQNIYKNTVKAQAPQLFLTKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QQNEFYEKLPYQLTNAQQRAITEILDDIKKSNAMNRLLQGDVGAGKTIVATIAAYAAVKS
HHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GYQVAMMAPTEILAEQHFSFLSQYLASFDIKVIPLLGKLSAKQTRESLDKIKDQKDCVVV
CCEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEE
GTHAIFQERVEYCNLGLVIVDEQHRFGVEQRLALVSKSSSNFSDLTPHQLIISATPIPRT
EHHHHHHHHHHHHCCCEEEECCHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHH
LAMTLYGNLKLSILDELPPKRKPIITTVLNRAKKQNLIEKVKQAVLRGEQVYWVCPLVEE
HHHEEECCEEEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
SENMDFLQDVKTLYQELLEALGKENVGLVYGSMKSKDKIEQMAAFKAKKYAVLVATTVIE
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHEEHHHHHHHH
VGVDVPNATIMIIDNAERLGISQLHQLRGRVGRGAKESYCILLYSDKISEVGKRRLSLVR
HCCCCCCCEEEEEECCHHCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHH
ESQDGFYLAEKDLEIRGAGDILGKEQSGVSTFKTFDINEYYDNYDKVVEFADMLDKHYPE
CCCCCEEEEECCEEEECCCCCCCCCCCCCCCEEEECCHHHHCCHHHHHHHHHHHHHHHHH
LVDKLIQRWFDRRVNYVEV
HHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]