Definition Francisella tularensis subsp. holarctica LVS chromosome, complete genome.
Accession NC_007880
Length 1,895,994

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The map label for this gene is 89255857

Identifier: 89255857

GI number: 89255857

Start: 421977

End: 423032

Strand: Reverse

Name: 89255857

Synonym: FTL_0447

Alternate gene names: NA

Gene position: 423032-421977 (Counterclockwise)

Preceding gene: 89255858

Following gene: 89255855

Centisome position: 22.31

GC content: 27.65

Gene sequence:

>1056_bases
ATGATAAATATATATAAAATTATATTAGTATTAAGTATAGTAGCAATATTCTACTCGGATATATTTGGATATGGTGATAT
TCCTCCACAAAAGCCAACGCTTATAAAGACCTCAGCATTCATTACTGATATCCAAAGCTTAGATGAAATGAATGAACAAT
TACAAATTGATGTGATTTTTAGATTTAGCTGGAATGATCAAAGATTAGAATTTGATAAAAATGAAGAAAAAACTCCATAT
AAATTATATCAAGGCGACTTTCAATATGATGAAGTTTTTGAAGGTTGGAAACCACAAATTTCTATAATTAATGAAATTGG
AACTCCTCAAATAAAAGCTAGACAAATAAAGATTTACCCTAATGGCGATATTATATACACCGAGCAACGTACTTTACATC
TTGAAACTCCAATGCGACTTGAGAAATTCCCATTTGATAAGCAAACTTTAAAAACGTATATAATACCATTTGGCTATAAT
TCTAAAGAAGTACAATTAATAGTCGAGCCAAACCATAAAATTACAGTTAAAGACTATGTTAAAGATCATCCAAATATAAA
TGTAGCTGAATGGCATCTAAGTAACTTCGATCTAAAAAATATAGAGCCTATAAAATACTACTATGGAAAACCACAAAGAA
TATCAATGCTAGAGTTTAGTATCTCATTAGAAAGAAAACCTACTAATATTCTTTTAAAAGTACTGATTCCATTGACATTG
TTAGTATTAGCAATGTGGGCAATATTTTGGATGGATACAAAAGCTTTATCAGATAGATTAAACATAACATTTATAGGAAT
TTTATCTGTAATCGCATATCAATTCTTAATCGAAGGAGAAATACTTGATATTGACTATTTAACTTTTACCGATGGATTTC
TACTATTATCTTTTTCTATTTTATTTTCAACAGTTTTAGAAAGTTTAGCTGTTTACTGGCTAATAAAATTAAACAAAGAT
AAACTAGCTAGAAAGATGGATATATTCTCAAGGTTTGCTTTTCCTATTAGCTACTTAGTTTTGATAACTTCTCTTTATTT
TATCTATTTACATTAA

Upstream 100 bases:

>100_bases
TTTGAAAACAATTATTTATTTTGAAAACAATTATTTAGTAAATTTGGCATATAGTTACTTATTTAGTAAAATAAACTAAG
AATATTAAATTTTATGATAA

Downstream 100 bases:

>100_bases
ATTAGTCATTACTTACTATTCAATATTTAATAATTGCGGCACTATAGCTACAATTATATTTGTAAATTAAATTAGCTAAG
ATTTTGATAAATAATTATAC

Product: hypothetical protein

Products: NA

Alternate protein names: ELIC [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MINIYKIILVLSIVAIFYSDIFGYGDIPPQKPTLIKTSAFITDIQSLDEMNEQLQIDVIFRFSWNDQRLEFDKNEEKTPY
KLYQGDFQYDEVFEGWKPQISIINEIGTPQIKARQIKIYPNGDIIYTEQRTLHLETPMRLEKFPFDKQTLKTYIIPFGYN
SKEVQLIVEPNHKITVKDYVKDHPNINVAEWHLSNFDLKNIEPIKYYYGKPQRISMLEFSISLERKPTNILLKVLIPLTL
LVLAMWAIFWMDTKALSDRLNITFIGILSVIAYQFLIEGEILDIDYLTFTDGFLLLSFSILFSTVLESLAVYWLIKLNKD
KLARKMDIFSRFAFPISYLVLITSLYFIYLH

Sequences:

>Translated_351_residues
MINIYKIILVLSIVAIFYSDIFGYGDIPPQKPTLIKTSAFITDIQSLDEMNEQLQIDVIFRFSWNDQRLEFDKNEEKTPY
KLYQGDFQYDEVFEGWKPQISIINEIGTPQIKARQIKIYPNGDIIYTEQRTLHLETPMRLEKFPFDKQTLKTYIIPFGYN
SKEVQLIVEPNHKITVKDYVKDHPNINVAEWHLSNFDLKNIEPIKYYYGKPQRISMLEFSISLERKPTNILLKVLIPLTL
LVLAMWAIFWMDTKALSDRLNITFIGILSVIAYQFLIEGEILDIDYLTFTDGFLLLSFSILFSTVLESLAVYWLIKLNKD
KLARKMDIFSRFAFPISYLVLITSLYFIYLH
>Mature_351_residues
MINIYKIILVLSIVAIFYSDIFGYGDIPPQKPTLIKTSAFITDIQSLDEMNEQLQIDVIFRFSWNDQRLEFDKNEEKTPY
KLYQGDFQYDEVFEGWKPQISIINEIGTPQIKARQIKIYPNGDIIYTEQRTLHLETPMRLEKFPFDKQTLKTYIIPFGYN
SKEVQLIVEPNHKITVKDYVKDHPNINVAEWHLSNFDLKNIEPIKYYYGKPQRISMLEFSISLERKPTNILLKVLIPLTL
LVLAMWAIFWMDTKALSDRLNITFIGILSVIAYQFLIEGEILDIDYLTFTDGFLLLSFSILFSTVLESLAVYWLIKLNKD
KLARKMDIFSRFAFPISYLVLITSLYFIYLH

Specific function: Mediates cation-selective currents but does not discriminate between different monovalent cations [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family [H]

Homologues:

Organism=Homo sapiens, GI110347433, Length=298, Percent_Identity=24.8322147651007, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI110347441, Length=298, Percent_Identity=24.496644295302, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI218156328, Length=301, Percent_Identity=23.9202657807309, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI169646728, Length=296, Percent_Identity=24.6621621621622, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI169646723, Length=296, Percent_Identity=24.6621621621622, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI4504021, Length=296, Percent_Identity=24.6621621621622, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI119372310, Length=295, Percent_Identity=23.0508474576271, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI225903367, Length=295, Percent_Identity=23.0508474576271, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38788135, Length=300, Percent_Identity=23.6666666666667, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI38788155, Length=300, Percent_Identity=23.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI284925161, Length=273, Percent_Identity=24.5421245421245, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI288683407, Length=247, Percent_Identity=25.5060728744939, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI157389018, Length=307, Percent_Identity=22.8013029315961, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI153266866, Length=303, Percent_Identity=21.7821782178218, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI260593684, Length=309, Percent_Identity=21.3592233009709, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4504023, Length=309, Percent_Identity=21.3592233009709, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI157743288, Length=313, Percent_Identity=19.8083067092652, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI110347416, Length=282, Percent_Identity=22.6950354609929, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4557603, Length=292, Percent_Identity=22.9452054794521, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI259013560, Length=289, Percent_Identity=22.4913494809689, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503861, Length=289, Percent_Identity=22.4913494809689, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194097327, Length=294, Percent_Identity=21.4285714285714, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194097386, Length=291, Percent_Identity=22.680412371134, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4503867, Length=280, Percent_Identity=20.7142857142857, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4503865, Length=280, Percent_Identity=20, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI12548788, Length=280, Percent_Identity=20.7142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI12548785, Length=280, Percent_Identity=20, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI268838843, Length=288, Percent_Identity=21.1805555555556, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI189083734, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI189083732, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI189083730, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI189083728, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI189083726, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI189083724, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI38327554, Length=297, Percent_Identity=21.2121212121212, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI167000817, Length=296, Percent_Identity=22.2972972972973, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI167000751, Length=296, Percent_Identity=22.2972972972973, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI7657106, Length=258, Percent_Identity=24.031007751938, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI300797181, Length=263, Percent_Identity=20.532319391635, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI260593686, Length=241, Percent_Identity=21.9917012448133, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71980442, Length=295, Percent_Identity=22.7118644067797, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71980440, Length=374, Percent_Identity=20.855614973262, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI72000177, Length=303, Percent_Identity=23.7623762376238, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI72000175, Length=303, Percent_Identity=23.7623762376238, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71998246, Length=292, Percent_Identity=24.3150684931507, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559548, Length=329, Percent_Identity=22.7963525835866, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984488, Length=294, Percent_Identity=23.469387755102, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988451, Length=297, Percent_Identity=22.8956228956229, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32564038, Length=309, Percent_Identity=22.6537216828479, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17561822, Length=279, Percent_Identity=21.8637992831541, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71991415, Length=304, Percent_Identity=22.3684210526316, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996779, Length=290, Percent_Identity=23.448275862069, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115535200, Length=317, Percent_Identity=24.2902208201893, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71991392, Length=320, Percent_Identity=22.8125, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71996759, Length=281, Percent_Identity=22.4199288256228, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17539428, Length=316, Percent_Identity=23.1012658227848, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71993333, Length=311, Percent_Identity=20.9003215434084, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991411, Length=321, Percent_Identity=21.183800623053, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991404, Length=321, Percent_Identity=21.183800623053, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991399, Length=321, Percent_Identity=21.183800623053, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991443, Length=289, Percent_Identity=24.2214532871972, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507873, Length=301, Percent_Identity=20.9302325581395, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212646285, Length=326, Percent_Identity=22.0858895705521, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532178, Length=281, Percent_Identity=19.5729537366548, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532183, Length=281, Percent_Identity=19.5729537366548, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71991384, Length=332, Percent_Identity=22.289156626506, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86561093, Length=308, Percent_Identity=23.0519480519481, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71981619, Length=294, Percent_Identity=21.0884353741497, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25154582, Length=340, Percent_Identity=22.9411764705882, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71998208, Length=275, Percent_Identity=23.2727272727273, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25154135, Length=275, Percent_Identity=23.2727272727273, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71999841, Length=275, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71999941, Length=304, Percent_Identity=24.3421052631579, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17540850, Length=301, Percent_Identity=23.2558139534884, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI281360961, Length=295, Percent_Identity=25.4237288135593, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281360963, Length=295, Percent_Identity=25.4237288135593, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24648251, Length=300, Percent_Identity=22, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281362085, Length=285, Percent_Identity=22.4561403508772, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI85725242, Length=302, Percent_Identity=22.5165562913907, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648249, Length=302, Percent_Identity=22.5165562913907, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281362087, Length=302, Percent_Identity=22.1854304635762, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62472736, Length=304, Percent_Identity=22.6973684210526, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362083, Length=286, Percent_Identity=22.7272727272727, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24651625, Length=293, Percent_Identity=21.8430034129693, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24642352, Length=299, Percent_Identity=22.4080267558528, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45555535, Length=299, Percent_Identity=22.4080267558528, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17738049, Length=305, Percent_Identity=21.9672131147541, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28573876, Length=294, Percent_Identity=23.1292517006803, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006202
- InterPro:   IPR006201
- InterPro:   IPR006029 [H]

Pfam domain/function: PF02931 Neur_chan_LBD [H]

EC number: NA

Molecular weight: Translated: 41344; Mature: 41344

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MINIYKIILVLSIVAIFYSDIFGYGDIPPQKPTLIKTSAFITDIQSLDEMNEQLQIDVIF
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEEEEEE
RFSWNDQRLEFDKNEEKTPYKLYQGDFQYDEVFEGWKPQISIINEIGTPQIKARQIKIYP
EEECCCCEEECCCCCCCCCEEEECCCCCHHHHHCCCCCCCCEEHHCCCCCEEEEEEEEEE
NGDIIYTEQRTLHLETPMRLEKFPFDKQTLKTYIIPFGYNSKEVQLIVEPNHKITVKDYV
CCCEEEECCCEEEECCCCCHHCCCCCHHHHEEEEEEECCCCCEEEEEECCCCEEEEHHHH
KDHPNINVAEWHLSNFDLKNIEPIKYYYGKPQRISMLEFSISLERKPTNILLKVLIPLTL
CCCCCCEEEEEEECCCCCCCCCCCCEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHH
LVLAMWAIFWMDTKALSDRLNITFIGILSVIAYQFLIEGEILDIDYLTFTDGFLLLSFSI
HHHHHHHHHHHCHHHHHCCCCEEHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHH
LFSTVLESLAVYWLIKLNKDKLARKMDIFSRFAFPISYLVLITSLYFIYLH
HHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
>Mature Secondary Structure
MINIYKIILVLSIVAIFYSDIFGYGDIPPQKPTLIKTSAFITDIQSLDEMNEQLQIDVIF
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCEEEEEEEE
RFSWNDQRLEFDKNEEKTPYKLYQGDFQYDEVFEGWKPQISIINEIGTPQIKARQIKIYP
EEECCCCEEECCCCCCCCCEEEECCCCCHHHHHCCCCCCCCEEHHCCCCCEEEEEEEEEE
NGDIIYTEQRTLHLETPMRLEKFPFDKQTLKTYIIPFGYNSKEVQLIVEPNHKITVKDYV
CCCEEEECCCEEEECCCCCHHCCCCCHHHHEEEEEEECCCCCEEEEEECCCCEEEEHHHH
KDHPNINVAEWHLSNFDLKNIEPIKYYYGKPQRISMLEFSISLERKPTNILLKVLIPLTL
CCCCCCEEEEEEECCCCCCCCCCCCEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHH
LVLAMWAIFWMDTKALSDRLNITFIGILSVIAYQFLIEGEILDIDYLTFTDGFLLLSFSI
HHHHHHHHHHHCHHHHHCCCCEEHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHH
LFSTVLESLAVYWLIKLNKDKLARKMDIFSRFAFPISYLVLITSLYFIYLH
HHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA