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The map label for this gene is yjjL [H]

Identifier: 89255853

GI number: 89255853

Start: 410837

End: 412141

Strand: Reverse

Name: yjjL [H]

Synonym: FTL_0443

Alternate gene names: 89255853

Gene position: 412141-410837 (Counterclockwise)

Preceding gene: 89255854

Following gene: 89255847

Centisome position: 21.74

GC content: 33.72

Gene sequence:

>1305_bases
ATGGTAAAGGTATATATATACTTGAGCCACATGAGGGTGCTCAACCAGGTATGCGTGTCAAATAATATAAGCTCTCCCAC
AATGAAAAAATATTACTACAATACTTTAATAATTCTTTTACTGTTCTTTTTGGCATTACTAAATTATGTTGACAGATCAA
CTCTAAGTATAGCTAATACTGAAATAGCTAACGCTTTTAACATAACGCCAACAGAAATGGGGATATTACTATCCGCTTTC
ATGTGGTCATATGCTATTGCTAGTTTACCAGCAGGATATATGGTTGATCGTTTAGGTGTTAATAAAGTAATGTTAATAAG
TATGATTGCATGGTCTGTAGCGTGTATATTAGGAGGTTTTGTAATAGGATTTTACTCAATCTTACTAACACGTATACTGC
TTGGTCTTGCTGAAGCTCCTTTTTTTATAGTAGCTACTAGGATAATCCAACATCGTTTTCCAAGCTCTCAAAGAGGACTT
ATGTCATCTATAATTGCTTTAGGGCCAAGATTAGCAAATATTCTTGCACCTTTAATATTAGTTGGCTTAATGCTATTAAT
AGATTGGCGAGGTATGTTTATAATATTAGGTGTTGTAGGACTAATTGCTGCGATTGGCTGGAAGCTTCTACATACTAAAG
AAACACTAGAGCATACAACAACAATTATTAAAAAGTCTCAAAAGATTTCCATTTCCGAGACTCTAAGAAATAAAAACGTT
GTTTACTTATGTATCGGAAATCTATGTTCATCTTATGCCTACTGGCTATTTTTAACATGGCTGCCCTTCTATTTTATAAA
AGTAAAACATCTAACCCTCTCACAAATGAGTATTGCAACATCTGCTTCTTTTATTTCAGGAGTTGCTTCTGTAATGCTAG
GTGGGATTATCTCTGATTTTATGATAAAAAAGGGATATACTGCTGTCTTTGCACGTCTAACTCCTATAATTGCTGGATGC
TTAGTTGCGTCTATAGCGATCCTAGCATTACCATTTATTGATAATATTTTTGTTATCGTTTGTGTAATTGGCGTCACTAT
CTTCTACTTAGGACTAAGAATATCTCCAACATGGGCATTAGTTGCTGATATTTCTCCATACAGTTTAGTAGGAACAATTG
GTGGATTACAAAACTTTGCTAATTTTGTTGGCGCTGGGTTAGCCCCACTTATTACAGGAATAATACTACAATCAACAAAT
GATAATTTTATGATTATATTTATATTCAGTGGAATTATTTGTCTATTCGGCTCAATAATATATATGCTCATTCGCGATAA
ACGAGCTCAAAATGAGACAATTTAG

Upstream 100 bases:

>100_bases
CCTGAAGATTTAATTGGCAAGCATACTATAATGGTAGCAAATCTAGCTCCTAGAAAAATGAAATTTGGAATGTCTGAGGG
CATGGTTTTAGCTGCTGGAG

Downstream 100 bases:

>100_bases
TGCACTGTAATTTTTATTTTGCCTTTGGTTATATTTTTAATTTCCTCTAAGAACATATATTTATCAGATGCAACAATCTT
AATAATTTTAGAAATATTAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MVKVYIYLSHMRVLNQVCVSNNISSPTMKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAF
MWSYAIASLPAGYMVDRLGVNKVMLISMIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGL
MSSIIALGPRLANILAPLILVGLMLLIDWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNV
VYLCIGNLCSSYAYWLFLTWLPFYFIKVKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGC
LVASIAILALPFIDNIFVIVCVIGVTIFYLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTN
DNFMIIFIFSGIICLFGSIIYMLIRDKRAQNETI

Sequences:

>Translated_434_residues
MVKVYIYLSHMRVLNQVCVSNNISSPTMKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAF
MWSYAIASLPAGYMVDRLGVNKVMLISMIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGL
MSSIIALGPRLANILAPLILVGLMLLIDWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNV
VYLCIGNLCSSYAYWLFLTWLPFYFIKVKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGC
LVASIAILALPFIDNIFVIVCVIGVTIFYLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTN
DNFMIIFIFSGIICLFGSIIYMLIRDKRAQNETI
>Mature_434_residues
MVKVYIYLSHMRVLNQVCVSNNISSPTMKKYYYNTLIILLLFFLALLNYVDRSTLSIANTEIANAFNITPTEMGILLSAF
MWSYAIASLPAGYMVDRLGVNKVMLISMIAWSVACILGGFVIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGL
MSSIIALGPRLANILAPLILVGLMLLIDWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNV
VYLCIGNLCSSYAYWLFLTWLPFYFIKVKHLTLSQMSIATSASFISGVASVMLGGIISDFMIKKGYTAVFARLTPIIAGC
LVASIAILALPFIDNIFVIVCVIGVTIFYLGLRISPTWALVADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTN
DNFMIIFIFSGIICLFGSIIYMLIRDKRAQNETI

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=388, Percent_Identity=23.4536082474227, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI148743791, Length=394, Percent_Identity=22.5888324873096, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI9966811, Length=413, Percent_Identity=20.8232445520581, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI185136021, Length=409, Percent_Identity=24.6943765281174, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI21322234, Length=415, Percent_Identity=21.6867469879518, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI215490102, Length=133, Percent_Identity=33.0827067669173, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI215490096, Length=133, Percent_Identity=33.0827067669173, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI14042968, Length=133, Percent_Identity=33.0827067669173, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI9945322, Length=413, Percent_Identity=19.6125907990315, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI2367379, Length=415, Percent_Identity=31.0843373493976, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=27.0588235294118, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1789515, Length=426, Percent_Identity=28.8732394366197, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1789152, Length=453, Percent_Identity=28.6975717439294, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI2367193, Length=428, Percent_Identity=20.7943925233645, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=413, Percent_Identity=21.0653753026634, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI193205400, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24654039, Length=357, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17864456, Length=357, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573708, Length=404, Percent_Identity=20.5445544554455, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573707, Length=404, Percent_Identity=20.5445544554455, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24580790, Length=372, Percent_Identity=23.6559139784946, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24654037, Length=348, Percent_Identity=23.2758620689655, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654041, Length=348, Percent_Identity=23.2758620689655, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24658658, Length=433, Percent_Identity=21.9399538106236, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654044, Length=231, Percent_Identity=25.5411255411255, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45550460, Length=453, Percent_Identity=20.0883002207506, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20130167, Length=445, Percent_Identity=21.3483146067416, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583789, Length=403, Percent_Identity=19.106699751861, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47829; Mature: 47829

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVYIYLSHMRVLNQVCVSNNISSPTMKKYYYNTLIILLLFFLALLNYVDRSTLSIANT
CEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
EIANAFNITPTEMGILLSAFMWSYAIASLPAGYMVDRLGVNKVMLISMIAWSVACILGGF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGLMSSIIALGPRLANILAPLIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGLMLLIDWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCE
VYLCIGNLCSSYAYWLFLTWLPFYFIKVKHLTLSQMSIATSASFISGVASVMLGGIISDF
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIKKGYTAVFARLTPIIAGCLVASIAILALPFIDNIFVIVCVIGVTIFYLGLRISPTWAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTNDNFMIIFIFSGIICLFGSII
EECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHH
YMLIRDKRAQNETI
HHHHHHHCCCCCCC
>Mature Secondary Structure
MVKVYIYLSHMRVLNQVCVSNNISSPTMKKYYYNTLIILLLFFLALLNYVDRSTLSIANT
CEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
EIANAFNITPTEMGILLSAFMWSYAIASLPAGYMVDRLGVNKVMLISMIAWSVACILGGF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VIGFYSILLTRILLGLAEAPFFIVATRIIQHRFPSSQRGLMSSIIALGPRLANILAPLIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGLMLLIDWRGMFIILGVVGLIAAIGWKLLHTKETLEHTTTIIKKSQKISISETLRNKNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCE
VYLCIGNLCSSYAYWLFLTWLPFYFIKVKHLTLSQMSIATSASFISGVASVMLGGIISDF
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIKKGYTAVFARLTPIIAGCLVASIAILALPFIDNIFVIVCVIGVTIFYLGLRISPTWAL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VADISPYSLVGTIGGLQNFANFVGAGLAPLITGIILQSTNDNFMIIFIFSGIICLFGSII
EECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHH
YMLIRDKRAQNETI
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]