Click here to switch to the map view.

The map label for this gene is moaC

Identifier: 89054367

GI number: 89054367

Start: 1865498

End: 1865989

Strand: Reverse

Name: moaC

Synonym: Jann_1876

Alternate gene names: 89054367

Gene position: 1865989-1865498 (Counterclockwise)

Preceding gene: 89054368

Following gene: 89054366

Centisome position: 43.21

GC content: 62.6

Gene sequence:

>492_bases
ATGGCGCGGCTCACGCATTTCGACGGCGACGGTCAGGCCCATATGGTCGATGTCTCGGGCAAGGCTGTGACGGACCGCAT
AGCCGTCGCGGACTGCTACATTAAGATGACGACGCAAACGCTTGATTTGGTTGAACAAGGCACTGCAAAGAAGGGCGATG
TTCTGGGCGTCGCCCGGCTGGCGGGCATTATGGGCGCGAAGAAATGTGCCGACCTGATCCCGCTCTGCCATCCCTTGCCG
ATCACCAAGGTGGCCGTTGATCTGGTGCCGGACGCGTCCCTTCCGGGCGTGCGTATCACCGCGACGGTGAAGACCTCCGG
CCAGACGGGGGTGGAGATGGAGGCGCTGACCGCCGCCTCCACCGCTGCGCTGACCGTCTATGACATGCTGAAAGCGGCGG
AGAAGACCATGGAAATCGGCGGCTTGCGCGTGGTTCTGAAAGACGGTGGCAAGTCCGGGCGCTTTGAAGCGCCGGAAGGA
TCTGCCCCATGA

Upstream 100 bases:

>100_bases
TGGCCCGCGTCGGGGCGCGGACGTTCCTGATCGGTGAAAGCCTGATGCGGCAGCCGGACGTGACGGCGGCGACCCAGGCC
TTGCTGGCAGATCCCGTCTG

Downstream 100 bases:

>100_bases
TCTCCGTCGAAGATGCCCTGCGCGCGTGCCTGGACCTTGCGGCCCCCGTGGGCTCCGAAACCGTGCCGTTGACCGATGCC
GGAGGCCGCGTGTTGACTGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MARLTHFDGDGQAHMVDVSGKAVTDRIAVADCYIKMTTQTLDLVEQGTAKKGDVLGVARLAGIMGAKKCADLIPLCHPLP
ITKVAVDLVPDASLPGVRITATVKTSGQTGVEMEALTAASTAALTVYDMLKAAEKTMEIGGLRVVLKDGGKSGRFEAPEG
SAP

Sequences:

>Translated_163_residues
MARLTHFDGDGQAHMVDVSGKAVTDRIAVADCYIKMTTQTLDLVEQGTAKKGDVLGVARLAGIMGAKKCADLIPLCHPLP
ITKVAVDLVPDASLPGVRITATVKTSGQTGVEMEALTAASTAALTVYDMLKAAEKTMEIGGLRVVLKDGGKSGRFEAPEG
SAP
>Mature_162_residues
ARLTHFDGDGQAHMVDVSGKAVTDRIAVADCYIKMTTQTLDLVEQGTAKKGDVLGVARLAGIMGAKKCADLIPLCHPLPI
TKVAVDLVPDASLPGVRITATVKTSGQTGVEMEALTAASTAALTVYDMLKAAEKTMEIGGLRVVLKDGGKSGRFEAPEGS
AP

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=53.2051282051282, Blast_Score=163, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=46.3087248322148, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=48.125, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=47.6190476190476, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_JANSC (Q28R69)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_509818.1
- ProteinModelPortal:   Q28R69
- SMR:   Q28R69
- STRING:   Q28R69
- GeneID:   3934327
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_1876
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   Q28R69
- ProtClustDB:   PRK09364
- BioCyc:   JSP290400:JANN_1876-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16879; Mature: 16748

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLTHFDGDGQAHMVDVSGKAVTDRIAVADCYIKMTTQTLDLVEQGTAKKGDVLGVARL
CCEEEEECCCCCEEEEEECCCCHHHEEEEEEEEEEEHHHHHHHHHCCCCCCCCCHHHHHH
AGIMGAKKCADLIPLCHPLPITKVAVDLVPDASLPGVRITATVKTSGQTGVEMEALTAAS
HHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCCCEEEEEEEEECCCCCCEEHHHHHHH
TAALTVYDMLKAAEKTMEIGGLRVVLKDGGKSGRFEAPEGSAP
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARLTHFDGDGQAHMVDVSGKAVTDRIAVADCYIKMTTQTLDLVEQGTAKKGDVLGVARL
CEEEEECCCCCEEEEEECCCCHHHEEEEEEEEEEEHHHHHHHHHCCCCCCCCCHHHHHH
AGIMGAKKCADLIPLCHPLPITKVAVDLVPDASLPGVRITATVKTSGQTGVEMEALTAAS
HHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCCCEEEEEEEEECCCCCCEEHHHHHHH
TAALTVYDMLKAAEKTMEIGGLRVVLKDGGKSGRFEAPEGSAP
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA