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The map label for this gene is comE [H]

Identifier: 89053893

GI number: 89053893

Start: 1371738

End: 1372292

Strand: Direct

Name: comE [H]

Synonym: Jann_1402

Alternate gene names: 89053893

Gene position: 1371738-1372292 (Clockwise)

Preceding gene: 89053892

Following gene: 89053894

Centisome position: 31.77

GC content: 59.28

Gene sequence:

>555_bases
ATGATCCGTTCCGAAATCCTGCGCGACATTGCGCCCATCCTGAACCCGCACCTTGTTGTTTGTAACATCGGTCTTCCCAG
CCAAGAACTGCACATGATCGACGACAACGCGCGCAACTTCTACATGCTTGGCACGATGGGGCTGTCGTCCTCCATCGGCC
TTGGTCTGGCGCTGGCGCAAGACAAGACGGTGATCTCCATCGATGGCGACGGGTCCGTTCTGACGAACCTCGGCACGCTG
CCGACCATCGCCAACAACGTGGCCGACAATTTCATCCTGCTGATCATCGACAACGGCTCCTATGGGTCCACCGGCGATCA
GCCGACCTATGCGGGCAAGCTGACGAAGCTGGAGAATGTCGCGAAGGCCTGCGGGTGTGAGAATGTGGTGGTCTGCGATG
ACGTCGACACCGGCAAGACGCTGCAAGCGGCCATCGACAGCAAGCAGATGACGATCATCGTGTCCAAATGCGACAGCGGC
AACATCAAGCTGCCCGTCATCACCATGGATCCGGTCGTGATCCGCGCCCGCTTCATGGACGCGGTGGCAAGCTGA

Upstream 100 bases:

>100_bases
ACGCGGATGAGCTGGACGCGATCCTGAAATACACGTTCATGTGCAATAAACCTGTGGCCATCCTGACCGATGCGTCCTTC
TGGGGAGGCTACGGCGACCA

Downstream 100 bases:

>100_bases
CGATGATCCATTCAAGTGCAGACGCGCGACGCCTGGCGAAGCGGCGTCTGCCCTGGATGGTGTTCGATTACATCGACGGT
GCCGCCGGGGCCGAGACGGG

Product: thiamine pyrophosphate enzyme-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIRSEILRDIAPILNPHLVVCNIGLPSQELHMIDDNARNFYMLGTMGLSSSIGLGLALAQDKTVISIDGDGSVLTNLGTL
PTIANNVADNFILLIIDNGSYGSTGDQPTYAGKLTKLENVAKACGCENVVVCDDVDTGKTLQAAIDSKQMTIIVSKCDSG
NIKLPVITMDPVVIRARFMDAVAS

Sequences:

>Translated_184_residues
MIRSEILRDIAPILNPHLVVCNIGLPSQELHMIDDNARNFYMLGTMGLSSSIGLGLALAQDKTVISIDGDGSVLTNLGTL
PTIANNVADNFILLIIDNGSYGSTGDQPTYAGKLTKLENVAKACGCENVVVCDDVDTGKTLQAAIDSKQMTIIVSKCDSG
NIKLPVITMDPVVIRARFMDAVAS
>Mature_184_residues
MIRSEILRDIAPILNPHLVVCNIGLPSQELHMIDDNARNFYMLGTMGLSSSIGLGLALAQDKTVISIDGDGSVLTNLGTL
PTIANNVADNFILLIIDNGSYGSTGDQPTYAGKLTKLENVAKACGCENVVVCDDVDTGKTLQAAIDSKQMTIIVSKCDSG
NIKLPVITMDPVVIRARFMDAVAS

Specific function: Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde [H]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022494
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C [H]

EC number: =4.1.1.79 [H]

Molecular weight: Translated: 19495; Mature: 19495

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSEILRDIAPILNPHLVVCNIGLPSQELHMIDDNARNFYMLGTMGLSSSIGLGLALAQ
CCHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEEC
DKTVISIDGDGSVLTNLGTLPTIANNVADNFILLIIDNGSYGSTGDQPTYAGKLTKLENV
CCEEEEECCCCCEEECCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
AKACGCENVVVCDDVDTGKTLQAAIDSKQMTIIVSKCDSGNIKLPVITMDPVVIRARFMD
HHHCCCCCEEEECCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEEEECCHHHHHHHHHH
AVAS
HHCC
>Mature Secondary Structure
MIRSEILRDIAPILNPHLVVCNIGLPSQELHMIDDNARNFYMLGTMGLSSSIGLGLALAQ
CCHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEEC
DKTVISIDGDGSVLTNLGTLPTIANNVADNFILLIIDNGSYGSTGDQPTYAGKLTKLENV
CCEEEEECCCCCEEECCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
AKACGCENVVVCDDVDTGKTLQAAIDSKQMTIIVSKCDSGNIKLPVITMDPVVIRARFMD
HHHCCCCCEEEECCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEEEECCHHHHHHHHHH
AVAS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 10940029 [H]