BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

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The map label for this gene is livF [H]

Identifier: 89053876

GI number: 89053876

Start: 1354961

End: 1355716

Strand: Direct

Name: livF [H]

Synonym: Jann_1385

Alternate gene names: 89053876

Gene position: 1354961-1355716 (Clockwise)

Preceding gene: 89053875

Following gene: 89053883

Centisome position: 31.38

GC content: 60.71

Gene sequence:

>756_bases
ATGAATACGACACCCAAACTTGACCCCAACGCCAACCGCGCGGCCACGGCACCGGCGTTCCTTTCGGTGTGGGAGTTGGA
GGCCTATTACGGCGAAAGCTACATCGTCCAGAAAATCAGCTTCAACGTCCACGAAGGGGAGATTCTGGCGCTTTTGGGCC
GTAACGGTGCGGGCAAGACCTCGACCCTGCGCGCCATCGCCCGCGTGGACGAGCCCGAGATGCGCCACGGTGAGATCTGG
TTGGACCACAAGCCGCTGCATCAAATGAAAAGCCATCAGGCTGCCGGTCTGGGTGTTGCGCTGGTCCCGGAAGATCGCCG
GATCATTCCCGGTCTCACGGTGGAAGAGAACCTGAAACTGGCCCAGATCGCACCGCCCGTGGGGTGGTCCCTGGAGCGGA
TCTATGAGCTGTTTCCCCGCCTGAAGGAGCGTCGCAAACAGGAAGGCGTGACGCTGTCAGGGGGCGAACAGCAGATGCTG
TCGATTGCCCGTGCCTTGGCGCGCGACATCAAGATCCTGCTGTTGGACGAGCCCTATGAGGGCCTTGCGCCGGTGATCGT
GCAGGAAATCGCCAAGACCCTGAATCTGATCCGTGACCAAGGCATCACGACGATCATCGTGGAGCAAAACGCCGTTGCGG
CGTTGAAACTGGCGGACCGTGCCGTGATCCTCGATACCGGCAGCGTGGTCTTTGACGGCGATGCAAAAGAGGTGCTGGAG
AATGAGGCGCTCCGCGAGGAATACCTCGCGATCTAG

Upstream 100 bases:

>100_bases
CATCCCGGAGAACATCAAGGGCCACCCGAAAGTGCGCGAAGCCTATCTTGGCGATGCGCAGGTCTAATCCTTTTGCCGAC
GGCTTGATCGGAGATCAAAC

Downstream 100 bases:

>100_bases
GGGCCGTGAGGTATACGTAACGACCTAACGAAACCTCCATTGAAAAAGCCGCGTCCCGATTGGGCGCGGCTTTTTCGATA
TTTGGAAGCGCAGTGATTTA

Product: ABC transporter-like protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNTTPKLDPNANRAATAPAFLSVWELEAYYGESYIVQKISFNVHEGEILALLGRNGAGKTSTLRAIARVDEPEMRHGEIW
LDHKPLHQMKSHQAAGLGVALVPEDRRIIPGLTVEENLKLAQIAPPVGWSLERIYELFPRLKERRKQEGVTLSGGEQQML
SIARALARDIKILLLDEPYEGLAPVIVQEIAKTLNLIRDQGITTIIVEQNAVAALKLADRAVILDTGSVVFDGDAKEVLE
NEALREEYLAI

Sequences:

>Translated_251_residues
MNTTPKLDPNANRAATAPAFLSVWELEAYYGESYIVQKISFNVHEGEILALLGRNGAGKTSTLRAIARVDEPEMRHGEIW
LDHKPLHQMKSHQAAGLGVALVPEDRRIIPGLTVEENLKLAQIAPPVGWSLERIYELFPRLKERRKQEGVTLSGGEQQML
SIARALARDIKILLLDEPYEGLAPVIVQEIAKTLNLIRDQGITTIIVEQNAVAALKLADRAVILDTGSVVFDGDAKEVLE
NEALREEYLAI
>Mature_251_residues
MNTTPKLDPNANRAATAPAFLSVWELEAYYGESYIVQKISFNVHEGEILALLGRNGAGKTSTLRAIARVDEPEMRHGEIW
LDHKPLHQMKSHQAAGLGVALVPEDRRIIPGLTVEENLKLAQIAPPVGWSLERIYELFPRLKERRKQEGVTLSGGEQQML
SIARALARDIKILLLDEPYEGLAPVIVQEIAKTLNLIRDQGITTIIVEQNAVAALKLADRAVILDTGSVVFDGDAKEVLE
NEALREEYLAI

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI11967971, Length=219, Percent_Identity=28.7671232876712, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI90421313, Length=239, Percent_Identity=31.3807531380753, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI153792144, Length=222, Percent_Identity=26.1261261261261, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI31657092, Length=222, Percent_Identity=28.8288288288288, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27477115, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27436953, Length=197, Percent_Identity=27.4111675126904, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI9961252, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4505771, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI9961250, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI21536376, Length=221, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI89111135, Length=218, Percent_Identity=27.9816513761468, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI190343023, Length=222, Percent_Identity=28.8288288288288, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI148612844, Length=254, Percent_Identity=24.8031496062992, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI105990541, Length=203, Percent_Identity=30.0492610837438, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI255708477, Length=254, Percent_Identity=24.8031496062992, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082268, Length=234, Percent_Identity=44.4444444444444, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789593, Length=237, Percent_Identity=32.0675105485232, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87081791, Length=242, Percent_Identity=28.5123966942149, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=29.1304347826087, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789991, Length=231, Percent_Identity=31.6017316017316, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790162, Length=252, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1787089, Length=227, Percent_Identity=32.5991189427313, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=31.7391304347826, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787029, Length=223, Percent_Identity=29.1479820627803, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790525, Length=240, Percent_Identity=25.8333333333333, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI48995001, Length=214, Percent_Identity=28.5046728971963, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787792, Length=234, Percent_Identity=26.9230769230769, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082267, Length=227, Percent_Identity=29.0748898678414, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790467, Length=222, Percent_Identity=31.5315315315315, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=30.8755760368664, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788450, Length=239, Percent_Identity=29.7071129707113, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789864, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788210, Length=227, Percent_Identity=27.3127753303965, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790544, Length=257, Percent_Identity=25.2918287937743, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786872, Length=223, Percent_Identity=28.6995515695067, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787112, Length=225, Percent_Identity=29.3333333333333, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=244, Percent_Identity=24.1803278688525, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786253, Length=228, Percent_Identity=27.6315789473684, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI145693107, Length=226, Percent_Identity=30.0884955752212, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787712, Length=210, Percent_Identity=27.6190476190476, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788897, Length=207, Percent_Identity=28.0193236714976, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790190, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787164, Length=206, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788761, Length=220, Percent_Identity=25.9090909090909, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786345, Length=229, Percent_Identity=27.9475982532751, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789032, Length=243, Percent_Identity=27.9835390946502, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788472, Length=228, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787105, Length=210, Percent_Identity=28.0952380952381, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789873, Length=209, Percent_Identity=25.8373205741627, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87081834, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787143, Length=221, Percent_Identity=27.1493212669683, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994997, Length=237, Percent_Identity=30.379746835443, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787547, Length=222, Percent_Identity=27.9279279279279, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48994943, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786654, Length=225, Percent_Identity=28, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788644, Length=241, Percent_Identity=26.5560165975104, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786398, Length=213, Percent_Identity=24.8826291079812, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786703, Length=206, Percent_Identity=31.0679611650485, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=28.9719626168224, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=24.4274809160305, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789891, Length=235, Percent_Identity=26.3829787234043, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=228, Percent_Identity=25.4385964912281, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=261, Percent_Identity=25.2873563218391, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI212646699, Length=221, Percent_Identity=28.0542986425339, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193211017, Length=214, Percent_Identity=28.5046728971963, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=227, Percent_Identity=26.8722466960352, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=214, Percent_Identity=28.5046728971963, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71996809, Length=214, Percent_Identity=28.5046728971963, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=221, Percent_Identity=27.6018099547511, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17543740, Length=217, Percent_Identity=25.3456221198157, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=216, Percent_Identity=28.2407407407407, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=228, Percent_Identity=27.6315789473684, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=212, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=261, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=221, Percent_Identity=27.6018099547511, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=217, Percent_Identity=28.110599078341, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539902, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=226, Percent_Identity=27.4336283185841, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988343, Length=212, Percent_Identity=29.2452830188679, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=227, Percent_Identity=25.9911894273128, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=226, Percent_Identity=24.7787610619469, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193209740, Length=226, Percent_Identity=28.3185840707965, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319856, Length=230, Percent_Identity=29.5652173913043, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323959, Length=222, Percent_Identity=25.6756756756757, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320339, Length=227, Percent_Identity=28.1938325991189, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24666092, Length=213, Percent_Identity=27.2300469483568, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28571871, Length=217, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221512771, Length=236, Percent_Identity=25, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648314, Length=217, Percent_Identity=26.2672811059908, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363262, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653245, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641565, Length=222, Percent_Identity=25.6756756756757, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582014, Length=172, Percent_Identity=32.5581395348837, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582012, Length=172, Percent_Identity=32.5581395348837, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24585091, Length=227, Percent_Identity=25.1101321585903, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357907, Length=228, Percent_Identity=27.1929824561404, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650855, Length=244, Percent_Identity=28.2786885245902, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650986, Length=220, Percent_Identity=25.4545454545455, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358185, Length=220, Percent_Identity=25.4545454545455, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650853, Length=244, Percent_Identity=28.2786885245902, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362751, Length=245, Percent_Identity=28.1632653061224, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28574259, Length=219, Percent_Identity=26.4840182648402, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17136662, Length=214, Percent_Identity=26.1682242990654, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643674, Length=219, Percent_Identity=24.6575342465753, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27785; Mature: 27785

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTPKLDPNANRAATAPAFLSVWELEAYYGESYIVQKISFNVHEGEILALLGRNGAGKT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEEECCCCCCH
STLRAIARVDEPEMRHGEIWLDHKPLHQMKSHQAAGLGVALVPEDRRIIPGLTVEENLKL
HHHHHHHHCCCCCCCCCCEEECCCHHHHHHHCCCCCCEEEECCCCCEECCCCCHHCCCEE
AQIAPPVGWSLERIYELFPRLKERRKQEGVTLSGGEQQMLSIARALARDIKILLLDEPYE
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEECCCCC
GLAPVIVQEIAKTLNLIRDQGITTIIVEQNAVAALKLADRAVILDTGSVVFDGDAKEVLE
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCEEEEECCCEEECCCHHHHHH
NEALREEYLAI
HHHHHHHHHCC
>Mature Secondary Structure
MNTTPKLDPNANRAATAPAFLSVWELEAYYGESYIVQKISFNVHEGEILALLGRNGAGKT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEEEECCCCCCH
STLRAIARVDEPEMRHGEIWLDHKPLHQMKSHQAAGLGVALVPEDRRIIPGLTVEENLKL
HHHHHHHHCCCCCCCCCCEEECCCHHHHHHHCCCCCCEEEECCCCCEECCCCCHHCCCEE
AQIAPPVGWSLERIYELFPRLKERRKQEGVTLSGGEQQMLSIARALARDIKILLLDEPYE
EEECCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEECCCCC
GLAPVIVQEIAKTLNLIRDQGITTIIVEQNAVAALKLADRAVILDTGSVVFDGDAKEVLE
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCEEEEECCCEEECCCHHHHHH
NEALREEYLAI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]