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The map label for this gene is glmS [H]

Identifier: 89053851

GI number: 89053851

Start: 1324072

End: 1325103

Strand: Direct

Name: glmS [H]

Synonym: Jann_1360

Alternate gene names: 89053851

Gene position: 1324072-1325103 (Clockwise)

Preceding gene: 89053850

Following gene: 89053852

Centisome position: 30.66

GC content: 62.98

Gene sequence:

>1032_bases
ATGACTGAGACTACATCCCAGATGCGACGAGAGGTACTTGAGATCCCCGCCGCAATTGACCGATTGCTATCGCAAGGCAC
GCCGGAGATCGCGCGGATCGCCGCGGCGGTCGCAAAGGCGGACCCCAGGTTTGCCGTGACGGTTGCGCGCGGGTCGTCGG
ACCATGCCTGCACCTTCCTGAAATACGCGCTGGAACTGGAATTGGGCCTGCCGGTCGCCTCCATCGGGCCGTCGGTTGCA
TCGATCTACGGGGCGCAGCTGAAGCTTGCGAATTCGATCACCTTGTCCGTCTCGCAATCGGGCAAAAGCCCGGACATCGT
CGCGATGAGCCGGGCGGCGACCGAGGGCGACAGTTTCACCGTGGCGATCACCAATGACGCGCAGTCTCCGCTGTCAGACG
CCAGCAGCCATACGATCGACATCCACGCGGGCCCGGAGATCAGCGTTGCGGCGACCAAGACGTTCGTGACCTCTGCGGCT
GCCGGTTTGATCCTGCTGGCGGAATGGAAGGATGACGACATCTTGCGGGCCGCCCTGCGTGGCTTGCCGGAGTGTCTGTC
CAAAGCCGCGACCCATGATTGGCCGGACTTGCGCGCCGCGATTGGATCCGCGTCCTCTCTGTTCACACTGGGGCGGGGTC
CGGCCTGGGCGATCTCGAACGAGGCGGCTTTGAAGTTCAAGGAAACCTGCCAGATCCACGCTGAAAGTTACTCCTCGGCT
GAGGTTCTGCATGGCCCTGTCTCCATCGTTGGCGGTGGCTTCCCTGTCCTGTGTTTCGCCAGTGGCGATGCGGCAGAAGC
CTCGGTCACCGACGTGGCAGACCAATTGGCCGCCAAAGGCGCGCGGGTGTTTGTGACGTCCGACAAAGCCGATACCGCCC
ATTGCCTGCCGCACGTCCGCACGGGCCACCCGTTGACCGATCCGCTGGCATTGATCGTGTCATTCTACGCGATGATCGAG
AAAGTTGCGGCAGAGCGGGGCGTGAACCCCGATGCGCCGAGGCACCTGAACAAGGTCACGGAAACCGTATGA

Upstream 100 bases:

>100_bases
TCTGGCGTCCGGCCAGATCGCGGAGTTCACAAAATCCATCTATCGCGGCGATGCCTACGACTTCGTGGCAGAGCTGCGCC
TTTGAGAAAGGCTGCCAATC

Downstream 100 bases:

>100_bases
GTGGCGGCTTGCGCGCCCTGACCGGGGCTGAGATCTTTGACGGCACGACGCGTCATGCCCGCCACGCATTGGTATGGGAT
GGCGGGGTTGTGCGTGGCAT

Product: glutamine-fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTETTSQMRREVLEIPAAIDRLLSQGTPEIARIAAAVAKADPRFAVTVARGSSDHACTFLKYALELELGLPVASIGPSVA
SIYGAQLKLANSITLSVSQSGKSPDIVAMSRAATEGDSFTVAITNDAQSPLSDASSHTIDIHAGPEISVAATKTFVTSAA
AGLILLAEWKDDDILRAALRGLPECLSKAATHDWPDLRAAIGSASSLFTLGRGPAWAISNEAALKFKETCQIHAESYSSA
EVLHGPVSIVGGGFPVLCFASGDAAEASVTDVADQLAAKGARVFVTSDKADTAHCLPHVRTGHPLTDPLALIVSFYAMIE
KVAAERGVNPDAPRHLNKVTETV

Sequences:

>Translated_343_residues
MTETTSQMRREVLEIPAAIDRLLSQGTPEIARIAAAVAKADPRFAVTVARGSSDHACTFLKYALELELGLPVASIGPSVA
SIYGAQLKLANSITLSVSQSGKSPDIVAMSRAATEGDSFTVAITNDAQSPLSDASSHTIDIHAGPEISVAATKTFVTSAA
AGLILLAEWKDDDILRAALRGLPECLSKAATHDWPDLRAAIGSASSLFTLGRGPAWAISNEAALKFKETCQIHAESYSSA
EVLHGPVSIVGGGFPVLCFASGDAAEASVTDVADQLAAKGARVFVTSDKADTAHCLPHVRTGHPLTDPLALIVSFYAMIE
KVAAERGVNPDAPRHLNKVTETV
>Mature_342_residues
TETTSQMRREVLEIPAAIDRLLSQGTPEIARIAAAVAKADPRFAVTVARGSSDHACTFLKYALELELGLPVASIGPSVAS
IYGAQLKLANSITLSVSQSGKSPDIVAMSRAATEGDSFTVAITNDAQSPLSDASSHTIDIHAGPEISVAATKTFVTSAAA
GLILLAEWKDDDILRAALRGLPECLSKAATHDWPDLRAAIGSASSLFTLGRGPAWAISNEAALKFKETCQIHAESYSSAE
VLHGPVSIVGGGFPVLCFASGDAAEASVTDVADQLAAKGARVFVTSDKADTAHCLPHVRTGHPLTDPLALIVSFYAMIEK
VAAERGVNPDAPRHLNKVTETV

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=320, Percent_Identity=28.4375, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI205277386, Length=324, Percent_Identity=28.0864197530864, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1790167, Length=357, Percent_Identity=27.1708683473389, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17532899, Length=358, Percent_Identity=26.536312849162, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17539970, Length=356, Percent_Identity=27.5280898876405, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17532897, Length=358, Percent_Identity=26.536312849162, Blast_Score=98, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6322745, Length=329, Percent_Identity=24.0121580547112, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323731, Length=332, Percent_Identity=21.6867469879518, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357745, Length=344, Percent_Identity=26.453488372093, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35763; Mature: 35632

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTSQMRREVLEIPAAIDRLLSQGTPEIARIAAAVAKADPRFAVTVARGSSDHACTFL
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
KYALELELGLPVASIGPSVASIYGAQLKLANSITLSVSQSGKSPDIVAMSRAATEGDSFT
HHHHHHHCCCCHHHCCCHHHHHHHHHEEEECEEEEEEECCCCCCCEEEEECCCCCCCCEE
VAITNDAQSPLSDASSHTIDIHAGPEISVAATKTFVTSAAAGLILLAEWKDDDILRAALR
EEEECCCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
GLPECLSKAATHDWPDLRAAIGSASSLFTLGRGPAWAISNEAALKFKETCQIHAESYSSA
HHHHHHHHHHCCCCHHHHHHHCCCHHEEEECCCCCEEECCCHHHHHHHHHHHHHCCCCCH
EVLHGPVSIVGGGFPVLCFASGDAAEASVTDVADQLAAKGARVFVTSDKADTAHCLPHVR
HHHCCCHHEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCC
TGHPLTDPLALIVSFYAMIEKVAAERGVNPDAPRHLNKVTETV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TETTSQMRREVLEIPAAIDRLLSQGTPEIARIAAAVAKADPRFAVTVARGSSDHACTFL
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
KYALELELGLPVASIGPSVASIYGAQLKLANSITLSVSQSGKSPDIVAMSRAATEGDSFT
HHHHHHHCCCCHHHCCCHHHHHHHHHEEEECEEEEEEECCCCCCCEEEEECCCCCCCCEE
VAITNDAQSPLSDASSHTIDIHAGPEISVAATKTFVTSAAAGLILLAEWKDDDILRAALR
EEEECCCCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
GLPECLSKAATHDWPDLRAAIGSASSLFTLGRGPAWAISNEAALKFKETCQIHAESYSSA
HHHHHHHHHHCCCCHHHHHHHCCCHHEEEECCCCCEEECCCHHHHHHHHHHHHHCCCCCH
EVLHGPVSIVGGGFPVLCFASGDAAEASVTDVADQLAAKGARVFVTSDKADTAHCLPHVR
HHHCCCHHEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHCCCCC
TGHPLTDPLALIVSFYAMIEKVAAERGVNPDAPRHLNKVTETV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]