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The map label for this gene is moeZ [H]

Identifier: 89053400

GI number: 89053400

Start: 864383

End: 865435

Strand: Direct

Name: moeZ [H]

Synonym: Jann_0909

Alternate gene names: 89053400

Gene position: 864383-865435 (Clockwise)

Preceding gene: 89053399

Following gene: 89053401

Centisome position: 20.02

GC content: 66.19

Gene sequence:

>1053_bases
ATGGTGTTTGTGTTCTTTCTTGCCGGGATCTTGTGGGCGCTGGGTCATCTGATGAAGGTGCCCATGGCGGCGCGGCTGAA
CATGCTGGCGCTGCTGTATGTTGCGGTTCTGGCGGTGCAGGTCGCCCTGCCCGACGGTCACGCGCTGCGGGAGATGACGG
GCGGGTCGATCGCGCTTTGGCTGTTGTTGGGGGCGGGCCTTGTGCTGGTCCTGGCGTACCGCGCGGTGTTGACGCGATTG
CGGGGACAGGCCGAGGAGATCGAAGCGGAGAGGGAGGCCAGCACCGCTGCGCCCACCGGCCCGTTTCTGGATGTCGAATT
AGAGCGATATGCGCGCCACATCACTCTGCCGGATATCGGTGGCGGTGGGCAGCTGGCGTTGAAACAGGCCTCTGTGCTGG
TGGTCGGGGCCGGGGGATTGGGGTCCCCGGTGCTGCTGTATCTGGCGGCGGCGGGTGTGGGGCGGATCGGGGTGATTGAT
GCCGACCGAGTCAGCCTGTCGAACCTGCAACGGCAGGTGATCCATACCGACGCGCGCAGCGATATGCCCAAGGTGTTTTC
AGCCGAGTTGGCGATGACGGCGCTCAACCCCCATATCGACGTGCGCCCCTACAACCGGGACCTGACCGCGGAGATCGCGG
AGGGCCTGTTCAGCGAGTACGATCTGGTCGTTGATGGCACCGACAGTTTCGCAGTGCGCGACATGATCAACCGGGCGGCC
GTGGCGGCGGGCCGTCCGGTGATTGCCGGAGCCATCTCCGCCTGGGAGGGGCAGGTGACGCTGTACGATCCCGCCGGGGG
CGCGCCCTGCATGGCGTGTATCTTCCCGGATGCGCCGGCGCCGGGCCTGTCAGCGACCTGCGCGGAGGCTGGTGTTATCG
GCGCGCTGCCGGGGATCATCGGGTCGATGATGGCGCTTGAGGTGATCAAGGAGATCACCGGCGCGGGCGAAGGCCTGCGC
GGACGCATGCTGATTTACGACGCACTCCATGCGGAAAGCCGCGTGATTTCCGTGCAGCGCCGCGTGGACTGCTCGGTTTG
CGACGGGGTTTGA

Upstream 100 bases:

>100_bases
CGGTGGTAGCACCCGTGGTGCAGGCCAGGTTTGAGCGTGTTGACGCCCTGGAAGAGACGGCGCGCGGCGCGGGTGGGTTT
GGGTCCACAGGGACGCGCTG

Downstream 100 bases:

>100_bases
CGCGGATTGGACGAAAGGCCGGGTCAGGGCTGGACGGCGGGGCCACGCGCGCCATACTGGCGAAAACCAACCGGGAGCAA
GATATGACTCGTTTTTTCGC

Product: UBA/THIF-type NAD/FAD binding

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MVFVFFLAGILWALGHLMKVPMAARLNMLALLYVAVLAVQVALPDGHALREMTGGSIALWLLLGAGLVLVLAYRAVLTRL
RGQAEEIEAEREASTAAPTGPFLDVELERYARHITLPDIGGGGQLALKQASVLVVGAGGLGSPVLLYLAAAGVGRIGVID
ADRVSLSNLQRQVIHTDARSDMPKVFSAELAMTALNPHIDVRPYNRDLTAEIAEGLFSEYDLVVDGTDSFAVRDMINRAA
VAAGRPVIAGAISAWEGQVTLYDPAGGAPCMACIFPDAPAPGLSATCAEAGVIGALPGIIGSMMALEVIKEITGAGEGLR
GRMLIYDALHAESRVISVQRRVDCSVCDGV

Sequences:

>Translated_350_residues
MVFVFFLAGILWALGHLMKVPMAARLNMLALLYVAVLAVQVALPDGHALREMTGGSIALWLLLGAGLVLVLAYRAVLTRL
RGQAEEIEAEREASTAAPTGPFLDVELERYARHITLPDIGGGGQLALKQASVLVVGAGGLGSPVLLYLAAAGVGRIGVID
ADRVSLSNLQRQVIHTDARSDMPKVFSAELAMTALNPHIDVRPYNRDLTAEIAEGLFSEYDLVVDGTDSFAVRDMINRAA
VAAGRPVIAGAISAWEGQVTLYDPAGGAPCMACIFPDAPAPGLSATCAEAGVIGALPGIIGSMMALEVIKEITGAGEGLR
GRMLIYDALHAESRVISVQRRVDCSVCDGV
>Mature_350_residues
MVFVFFLAGILWALGHLMKVPMAARLNMLALLYVAVLAVQVALPDGHALREMTGGSIALWLLLGAGLVLVLAYRAVLTRL
RGQAEEIEAEREASTAAPTGPFLDVELERYARHITLPDIGGGGQLALKQASVLVVGAGGLGSPVLLYLAAAGVGRIGVID
ADRVSLSNLQRQVIHTDARSDMPKVFSAELAMTALNPHIDVRPYNRDLTAEIAEGLFSEYDLVVDGTDSFAVRDMINRAA
VAAGRPVIAGAISAWEGQVTLYDPAGGAPCMACIFPDAPAPGLSATCAEAGVIGALPGIIGSMMALEVIKEITGAGEGLR
GRMLIYDALHAESRVISVQRRVDCSVCDGV

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=266, Percent_Identity=41.3533834586466, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI4885649, Length=147, Percent_Identity=31.9727891156463, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787048, Length=246, Percent_Identity=45.1219512195122, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI87082356, Length=246, Percent_Identity=37.8048780487805, Blast_Score=148, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17540406, Length=240, Percent_Identity=39.1666666666667, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI193203301, Length=153, Percent_Identity=32.0261437908497, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321903, Length=271, Percent_Identity=39.1143911439114, Blast_Score=179, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6320598, Length=164, Percent_Identity=26.219512195122, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582879, Length=268, Percent_Identity=40.2985074626866, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24660640, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI20129973, Length=164, Percent_Identity=30.4878048780488, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 36677; Mature: 36677

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00257 BOMBESIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFVFFLAGILWALGHLMKVPMAARLNMLALLYVAVLAVQVALPDGHALREMTGGSIALW
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHH
LLLGAGLVLVLAYRAVLTRLRGQAEEIEAEREASTAAPTGPFLDVELERYARHITLPDIG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCCC
GGGQLALKQASVLVVGAGGLGSPVLLYLAAAGVGRIGVIDADRVSLSNLQRQVIHTDARS
CCCCEEEEECEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHC
DMPKVFSAELAMTALNPHIDVRPYNRDLTAEIAEGLFSEYDLVVDGTDSFAVRDMINRAA
CCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
VAAGRPVIAGAISAWEGQVTLYDPAGGAPCMACIFPDAPAPGLSATCAEAGVIGALPGII
HHCCCCHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCHHHHHHHHH
GSMMALEVIKEITGAGEGLRGRMLIYDALHAESRVISVQRRVDCSVCDGV
HHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MVFVFFLAGILWALGHLMKVPMAARLNMLALLYVAVLAVQVALPDGHALREMTGGSIALW
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHH
LLLGAGLVLVLAYRAVLTRLRGQAEEIEAEREASTAAPTGPFLDVELERYARHITLPDIG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCCC
GGGQLALKQASVLVVGAGGLGSPVLLYLAAAGVGRIGVIDADRVSLSNLQRQVIHTDARS
CCCCEEEEECEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHC
DMPKVFSAELAMTALNPHIDVRPYNRDLTAEIAEGLFSEYDLVVDGTDSFAVRDMINRAA
CCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHH
VAAGRPVIAGAISAWEGQVTLYDPAGGAPCMACIFPDAPAPGLSATCAEAGVIGALPGII
HHCCCCHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCCCCCCHHHHHCCHHHHHHHHH
GSMMALEVIKEITGAGEGLRGRMLIYDALHAESRVISVQRRVDCSVCDGV
HHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]