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The map label for this gene is sucD [H]

Identifier: 89053318

GI number: 89053318

Start: 782571

End: 783452

Strand: Direct

Name: sucD [H]

Synonym: Jann_0827

Alternate gene names: 89053318

Gene position: 782571-783452 (Clockwise)

Preceding gene: 89053317

Following gene: 89053319

Centisome position: 18.12

GC content: 61.34

Gene sequence:

>882_bases
ATGGCCGTACTCGTTGATGAAAATACCAAGGTGATTTGCCAAGGCTTCACCGGATCCCAAGGCACGTTCCATTCGGAACA
AGCCATTGAATACGGGACCCAAATGGTCGGTGGCGTCACACCCGGAAAAGGCGGCATGACGCATCTGGACCTGCCGGTGT
TCAATTCGGTCCACGAGGCACGCCACGTGACGGACGCCAACGCATCAGTCATCTATGTGCCCCCGCCCTTTGCTGCGGAC
TCTATCCTTGAGGCGATTGATGCGGAGATGGAGTTGATCATCTGCATCACCGAGGGCATCCCGGTTTTGGACATGATGCG
CGTGAAGAGGGCGTTGGAGGGCTCGTCCTCCATCCTCGTGGGGCCGAACTGCCCCGGGGTGATCACGCCGGACGCCTGCA
AGATCGGCATCATGCCCGGCCATATCCACAAGCGTGGCTCCTGTGGCGTCGTCTCCCGCTCTGGCACGCTGACCTACGAG
GCCGTGAAGCAGACGACGGATGTGGGTCTGGGCCAATCCACCTGCGTCGGCATCGGCGGCGACCCGATCAAGGGCACCGA
GCATATCGACGTGCTGGAATGGTTCCTGGCCGATGATGAGACCGAGAGCATCATCATGATCGGTGAAATTGGAGGGTCCG
CCGAAGAAGAAGCCGCGCAATTCCTGGCCGATGAGAAGAAGAAGGGCCGTTGGAAGCCCACGGCAGGATTCATCGCCGGT
CGCACAGCCCCTCCGGGCCGTCGCATGGGCCACGCGGGCGCTATTGTCGCCGGTGGCAAAGGCGGCGCCGAGGACAAGAT
TGAGGCGATGAAATCCGCTGGCATCGTCGTGGCCGATAGCCCTGCGACCTTGGGCGAAGCCGTGCTGCAGGCGATTGGCT
AA

Upstream 100 bases:

>100_bases
GCACCAATATTCTCTCGCCCATGGCGGGCCTGCATTGCAGCCCGATCCCTGATCAAGGCCATGACCCAACCCATATCCCA
AACGACCACAGGAGGCCCCG

Downstream 100 bases:

>100_bases
GTGATGCGGCGGGCTGCCTCCCTCATTCTGGTTGGCCTCTTGGCGCTCGCGGGTCCCGCGCGCGCCGAGTTGTCCGACGG
GGAGAGGCAGACCATCGAAT

Product: succinyl-CoA synthetase (ADP-forming) subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAVLVDENTKVICQGFTGSQGTFHSEQAIEYGTQMVGGVTPGKGGMTHLDLPVFNSVHEARHVTDANASVIYVPPPFAAD
SILEAIDAEMELIICITEGIPVLDMMRVKRALEGSSSILVGPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYE
AVKQTTDVGLGQSTCVGIGGDPIKGTEHIDVLEWFLADDETESIIMIGEIGGSAEEEAAQFLADEKKKGRWKPTAGFIAG
RTAPPGRRMGHAGAIVAGGKGGAEDKIEAMKSAGIVVADSPATLGEAVLQAIG

Sequences:

>Translated_293_residues
MAVLVDENTKVICQGFTGSQGTFHSEQAIEYGTQMVGGVTPGKGGMTHLDLPVFNSVHEARHVTDANASVIYVPPPFAAD
SILEAIDAEMELIICITEGIPVLDMMRVKRALEGSSSILVGPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYE
AVKQTTDVGLGQSTCVGIGGDPIKGTEHIDVLEWFLADDETESIIMIGEIGGSAEEEAAQFLADEKKKGRWKPTAGFIAG
RTAPPGRRMGHAGAIVAGGKGGAEDKIEAMKSAGIVVADSPATLGEAVLQAIG
>Mature_292_residues
AVLVDENTKVICQGFTGSQGTFHSEQAIEYGTQMVGGVTPGKGGMTHLDLPVFNSVHEARHVTDANASVIYVPPPFAADS
ILEAIDAEMELIICITEGIPVLDMMRVKRALEGSSSILVGPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYEA
VKQTTDVGLGQSTCVGIGGDPIKGTEHIDVLEWFLADDETESIIMIGEIGGSAEEEAAQFLADEKKKGRWKPTAGFIAGR
TAPPGRRMGHAGAIVAGGKGGAEDKIEAMKSAGIVVADSPATLGEAVLQAIG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=68.1660899653979, Blast_Score=340, Evalue=7e-94,
Organism=Homo sapiens, GI38569423, Length=265, Percent_Identity=28.6792452830189, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI38569421, Length=265, Percent_Identity=28.6792452830189, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=68.4027777777778, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=63.573883161512, Blast_Score=354, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=63.3217993079585, Blast_Score=352, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17557344, Length=260, Percent_Identity=28.4615384615385, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=259, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=53.0821917808219, Blast_Score=288, Evalue=7e-79,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=59.581881533101, Blast_Score=353, Evalue=9e-98,
Organism=Drosophila melanogaster, GI28574296, Length=289, Percent_Identity=64.0138408304498, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI281363477, Length=265, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363475, Length=265, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363473, Length=265, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30391; Mature: 30260

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVDENTKVICQGFTGSQGTFHSEQAIEYGTQMVGGVTPGKGGMTHLDLPVFNSVHEA
CEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
RHVTDANASVIYVPPPFAADSILEAIDAEMELIICITEGIPVLDMMRVKRALEGSSSILV
HHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYEAVKQTTDVGLGQSTCVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIKGTEHIDVLEWFLADDETESIIMIGEIGGSAEEEAAQFLADEKKKGRWKPTAGFIAG
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
RTAPPGRRMGHAGAIVAGGKGGAEDKIEAMKSAGIVVADSPATLGEAVLQAIG
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
AVLVDENTKVICQGFTGSQGTFHSEQAIEYGTQMVGGVTPGKGGMTHLDLPVFNSVHEA
EEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
RHVTDANASVIYVPPPFAADSILEAIDAEMELIICITEGIPVLDMMRVKRALEGSSSILV
HHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYEAVKQTTDVGLGQSTCVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIKGTEHIDVLEWFLADDETESIIMIGEIGGSAEEEAAQFLADEKKKGRWKPTAGFIAG
CCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
RTAPPGRRMGHAGAIVAGGKGGAEDKIEAMKSAGIVVADSPATLGEAVLQAIG
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]