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The map label for this gene is coaX

Identifier: 88658521

GI number: 88658521

Start: 961175

End: 961945

Strand: Direct

Name: coaX

Synonym: ECH_0941

Alternate gene names: 88658521

Gene position: 961175-961945 (Clockwise)

Preceding gene: 88657936

Following gene: 88658155

Centisome position: 81.72

GC content: 28.15

Gene sequence:

>771_bases
ATGTTAATAGCAATAGATATAGGTAATACAAACATAAAATTAGCAATCTGTGCAAACAATAAAATTATAAAAAGGATAAC
TATCTCTTCACAATCTAGGAGAACAGCTGATGAATACTTCATATATTTAAATTCTACAATGAATCAATTAAACCTTGATT
ACAAAAATATAAATAATATTATCATATCAAGTGTAGTTCCAAGTATAACAAAGCCAATTATCGAATTAAGTCAAAATTAT
TTTAATATAGATCCCACAATTTTGAGTAACCATCATGCAGACATTTTTAATATTAAGATAAGCTTACAAAACAAAGTATT
AGGATCAGATAGGTTAGCAGATATAATTGCAGCAAGCAGTTTATATCCCCATAAAGATTTACTCATAATAGGTATGGGAA
CTGCAACAGTATTTAACTTATTAAATAAAGATAAATGCATATATGGACAAGCTATAGCACCTGGAGCACATATTTTAGCA
AAAAGTATGAGACAATACACTGCCCTATTACCAGAAGTATTAATTTCAAAACAAGACAAAGTAATACATGATAATATATA
CCACGCAATGGAATCAGGAATATACTGGGGATATATTACCATGATTAACGGAATGATTGAAAAAATAATAAAGGAAGAGG
AAAAAGATTTATATATAATAGCAACAGGAGGAAATTCTAACTTATTCTTTAATCACAAAACTGCTATTCACAACATCGAA
GTAGACTTAACCATAAAGGGTCTCATACAATTACATACTGTACTATCTTGA

Upstream 100 bases:

>100_bases
ATAGCTAATAAGATAAGCTTAGAGTTAGCTGATCTTTTAGCCGCAGATGGGTTTCCTACAGTACGCCATGCAATAGGCCA
TAATCACTAGCAGGTTTAAC

Downstream 100 bases:

>100_bases
TACCAAACCCTGAAATAATATAACTCATTGCTAACTGATATGATATAGTACAATAACTAAAAAGGACGAGGAAAAAGACT
TATACATAATAGCAACAGGA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLIAIDIGNTNIKLAICANNKIIKRITISSQSRRTADEYFIYLNSTMNQLNLDYKNINNIIISSVVPSITKPIIELSQNY
FNIDPTILSNHHADIFNIKISLQNKVLGSDRLADIIAASSLYPHKDLLIIGMGTATVFNLLNKDKCIYGQAIAPGAHILA
KSMRQYTALLPEVLISKQDKVIHDNIYHAMESGIYWGYITMINGMIEKIIKEEEKDLYIIATGGNSNLFFNHKTAIHNIE
VDLTIKGLIQLHTVLS

Sequences:

>Translated_256_residues
MLIAIDIGNTNIKLAICANNKIIKRITISSQSRRTADEYFIYLNSTMNQLNLDYKNINNIIISSVVPSITKPIIELSQNY
FNIDPTILSNHHADIFNIKISLQNKVLGSDRLADIIAASSLYPHKDLLIIGMGTATVFNLLNKDKCIYGQAIAPGAHILA
KSMRQYTALLPEVLISKQDKVIHDNIYHAMESGIYWGYITMINGMIEKIIKEEEKDLYIIATGGNSNLFFNHKTAIHNIE
VDLTIKGLIQLHTVLS
>Mature_256_residues
MLIAIDIGNTNIKLAICANNKIIKRITISSQSRRTADEYFIYLNSTMNQLNLDYKNINNIIISSVVPSITKPIIELSQNY
FNIDPTILSNHHADIFNIKISLQNKVLGSDRLADIIAASSLYPHKDLLIIGMGTATVFNLLNKDKCIYGQAIAPGAHILA
KSMRQYTALLPEVLISKQDKVIHDNIYHAMESGIYWGYITMINGMIEKIIKEEEKDLYIIATGGNSNLFFNHKTAIHNIE
VDLTIKGLIQLHTVLS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_EHRCR (Q2GFQ3)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507730.1
- ProteinModelPortal:   Q2GFQ3
- SMR:   Q2GFQ3
- STRING:   Q2GFQ3
- GeneID:   3928048
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_0941
- TIGR:   ECH_0941
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   ECHA205920:ECH_0941-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28697; Mature: 28697

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAIDIGNTNIKLAICANNKIIKRITISSQSRRTADEYFIYLNSTMNQLNLDYKNINNI
CEEEEEECCCEEEEEEEECCCEEEEEEECCCCCCCCCCEEEEEECCCCCEECCHHHHHHH
IISSVVPSITKPIIELSQNYFNIDPTILSNHHADIFNIKISLQNKVLGSDRLADIIAASS
HHHHHHHHHHHHHHHHHCCEECCCCCEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHCC
LYPHKDLLIIGMGTATVFNLLNKDKCIYGQAIAPGAHILAKSMRQYTALLPEVLISKQDK
CCCCCCEEEEEECHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
VIHDNIYHAMESGIYWGYITMINGMIEKIIKEEEKDLYIIATGGNSNLFFNHKTAIHNIE
CHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCEEEEEE
VDLTIKGLIQLHTVLS
EEEEEHHHHHHHHHCC
>Mature Secondary Structure
MLIAIDIGNTNIKLAICANNKIIKRITISSQSRRTADEYFIYLNSTMNQLNLDYKNINNI
CEEEEEECCCEEEEEEEECCCEEEEEEECCCCCCCCCCEEEEEECCCCCEECCHHHHHHH
IISSVVPSITKPIIELSQNYFNIDPTILSNHHADIFNIKISLQNKVLGSDRLADIIAASS
HHHHHHHHHHHHHHHHHCCEECCCCCEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHCC
LYPHKDLLIIGMGTATVFNLLNKDKCIYGQAIAPGAHILAKSMRQYTALLPEVLISKQDK
CCCCCCEEEEEECHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
VIHDNIYHAMESGIYWGYITMINGMIEKIIKEEEKDLYIIATGGNSNLFFNHKTAIHNIE
CHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCEEEEEE
VDLTIKGLIQLHTVLS
EEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA