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The map label for this gene is 88658371

Identifier: 88658371

GI number: 88658371

Start: 989839

End: 991461

Strand: Direct

Name: 88658371

Synonym: ECH_0966

Alternate gene names: NA

Gene position: 989839-991461 (Clockwise)

Preceding gene: 88658621

Following gene: 88658512

Centisome position: 84.15

GC content: 32.29

Gene sequence:

>1623_bases
ATGAATACTGATGATTTATTGTTCACACCCTTAGGCGGAGTCGGACAAATAGGCATGAATGTCAATTTATATCACTTAAA
TGGTAAATGGATAATTATTGATTTCGGAGCAGGATTTGCTGATGACAATATGCCAGGAATAGACATGATTGTTGCTGATA
TTAGTTTTATCAAAAAAAATAGAAAAAACTTGCTTGGTATAGTATTAACACATGCTCATGAAGATCACATAGGAGGCATA
CAATATCTGTGGAACGATTTGCAATGCCCAATATATGCAACAAAATTCACAGCTGCCTTATTACAAGCAAAATTGAAAGA
ATATCCATTTAGAATCAATATTACAGAAATCGACATCACAAAAAAATTAAATCTTGGCCCTTTTACTCTTGAGTTTATAA
ATTTGACACACTCCATACCAGAAATGAATGCAATTGCATTACACACTGAAAAAGGAATAGTAGTACATACAGGAGATTGG
AAGTTAGATGACAACCCAATTATTGGTCCTGTATCAAATACACAAAGATTAAAAGAATTAGGAGACGAAGGGGTTTTAGC
ACTTGTATGTGATTCAACAAATATATTTACTAAAAATAAATCAGGATCTGAGAGTGATTTAGAAAAAAGTATATTTAATA
TAATAAAAAACTGTAATCAAAAAGTTGCAGTATCTTTATTTGCATCTAATATTGCACGAATCTATACCATAGTAAACATT
GCAACAAAATTAGGTAGAAAAGTAGCAATACTGGGAAAATCTCTTATAAGAATTATACAAGCTGCACAAGACAGTGGGTA
TTTGCAAGATATACCAGAGTTCATCAATATCAATCAAGCAAATAAACTCCCAAATGATCAAGTCTTGCTTCTTTGTACTG
GTTGCCAAGGTGAAGAGCTAGCAGCAACTGCCAAACTTGCTAATAATTCTCATCCATTCACTAAATTAGATAATGGAGAT
ACTATTATCTTCTCTTCCAAGATCATTCCAGGAAATGAGAAACGGATATATAGTGTATTCAACAAATTCGTTAACATGGG
AGTTAATGTTATTACAGAATTTATGGAACATGTACACGTATCAGGGCACCCTTCAAAAAGTGAAGTATCTACTATGTATT
CATTAGTAAGGCCTAAATTATCCATCCCTGTACATGGAGAATACATACATATGCACGAACATGCAAAAGTTGCAAAACAA
TGCAACGTAGAAAAAGCGATAATAGTTCACCCAGGAGATGTAATAAGCCTCACAAAAAAACAAAAAATTAACTCTGTCAA
AGCTGGATACTTTGGAGTTGATGGCAATTTCTTACACCATCCCAAAGGCAATGTCATATCTATGCGAAAAAAGATGAGAG
ACGCAGGGATAATTATAATAACACTAGTTTTAAACAACAAAAAAGAATTATTAAAAGAACCAAGGATTTTTGCTCCAGGA
GTGCTAGATCATTCTAATAGTCAAGCAATTCTCAAAAAAGTCTCATCTAAAATAAGTAGCGAGCTTTATTCTAGAAAAAT
AAACAACATACGACAATACGTAGAAAATACAGTTTTCAATGCTTTAAAATATGACATCAAAAACAAACCATTTATTGAAG
TACAGCTAGAATACATAAATTAG

Upstream 100 bases:

>100_bases
CATAAAACATATATATACCAATATTTAATTATTCTAATGCTTTCCTTTAAACAATAAATAAGATATGCTGTTATTTAAGT
TTTTACAACGTACTTAATAA

Downstream 100 bases:

>100_bases
TACCTTTATCATTTATACAATAGAATACTTATATTGATAATCTATTGTAATTAAATATTCCTACCATAACATAGAACAAT
ATCTATCTATATAATTAACT

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNTDDLLFTPLGGVGQIGMNVNLYHLNGKWIIIDFGAGFADDNMPGIDMIVADISFIKKNRKNLLGIVLTHAHEDHIGGI
QYLWNDLQCPIYATKFTAALLQAKLKEYPFRINITEIDITKKLNLGPFTLEFINLTHSIPEMNAIALHTEKGIVVHTGDW
KLDDNPIIGPVSNTQRLKELGDEGVLALVCDSTNIFTKNKSGSESDLEKSIFNIIKNCNQKVAVSLFASNIARIYTIVNI
ATKLGRKVAILGKSLIRIIQAAQDSGYLQDIPEFININQANKLPNDQVLLLCTGCQGEELAATAKLANNSHPFTKLDNGD
TIIFSSKIIPGNEKRIYSVFNKFVNMGVNVITEFMEHVHVSGHPSKSEVSTMYSLVRPKLSIPVHGEYIHMHEHAKVAKQ
CNVEKAIIVHPGDVISLTKKQKINSVKAGYFGVDGNFLHHPKGNVISMRKKMRDAGIIIITLVLNNKKELLKEPRIFAPG
VLDHSNSQAILKKVSSKISSELYSRKINNIRQYVENTVFNALKYDIKNKPFIEVQLEYIN

Sequences:

>Translated_540_residues
MNTDDLLFTPLGGVGQIGMNVNLYHLNGKWIIIDFGAGFADDNMPGIDMIVADISFIKKNRKNLLGIVLTHAHEDHIGGI
QYLWNDLQCPIYATKFTAALLQAKLKEYPFRINITEIDITKKLNLGPFTLEFINLTHSIPEMNAIALHTEKGIVVHTGDW
KLDDNPIIGPVSNTQRLKELGDEGVLALVCDSTNIFTKNKSGSESDLEKSIFNIIKNCNQKVAVSLFASNIARIYTIVNI
ATKLGRKVAILGKSLIRIIQAAQDSGYLQDIPEFININQANKLPNDQVLLLCTGCQGEELAATAKLANNSHPFTKLDNGD
TIIFSSKIIPGNEKRIYSVFNKFVNMGVNVITEFMEHVHVSGHPSKSEVSTMYSLVRPKLSIPVHGEYIHMHEHAKVAKQ
CNVEKAIIVHPGDVISLTKKQKINSVKAGYFGVDGNFLHHPKGNVISMRKKMRDAGIIIITLVLNNKKELLKEPRIFAPG
VLDHSNSQAILKKVSSKISSELYSRKINNIRQYVENTVFNALKYDIKNKPFIEVQLEYIN
>Mature_540_residues
MNTDDLLFTPLGGVGQIGMNVNLYHLNGKWIIIDFGAGFADDNMPGIDMIVADISFIKKNRKNLLGIVLTHAHEDHIGGI
QYLWNDLQCPIYATKFTAALLQAKLKEYPFRINITEIDITKKLNLGPFTLEFINLTHSIPEMNAIALHTEKGIVVHTGDW
KLDDNPIIGPVSNTQRLKELGDEGVLALVCDSTNIFTKNKSGSESDLEKSIFNIIKNCNQKVAVSLFASNIARIYTIVNI
ATKLGRKVAILGKSLIRIIQAAQDSGYLQDIPEFININQANKLPNDQVLLLCTGCQGEELAATAKLANNSHPFTKLDNGD
TIIFSSKIIPGNEKRIYSVFNKFVNMGVNVITEFMEHVHVSGHPSKSEVSTMYSLVRPKLSIPVHGEYIHMHEHAKVAKQ
CNVEKAIIVHPGDVISLTKKQKINSVKAGYFGVDGNFLHHPKGNVISMRKKMRDAGIIIITLVLNNKKELLKEPRIFAPG
VLDHSNSQAILKKVSSKISSELYSRKINNIRQYVENTVFNALKYDIKNKPFIEVQLEYIN

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 60199; Mature: 60199

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDDLLFTPLGGVGQIGMNVNLYHLNGKWIIIDFGAGFADDNMPGIDMIVADISFIKKN
CCCCCEEEECCCCCCEECCEEEEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHC
RKNLLGIVLTHAHEDHIGGIQYLWNDLQCPIYATKFTAALLQAKLKEYPFRINITEIDIT
CCCEEEEEEEECCCCCCCCHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCEEEEEEEEEEE
KKLNLGPFTLEFINLTHSIPEMNAIALHTEKGIVVHTGDWKLDDNPIIGPVSNTQRLKEL
EECCCCCEEEEEEEHHCCCCCCCEEEEEECCCEEEECCCEEECCCCEECCCCCHHHHHHC
GDEGVLALVCDSTNIFTKNKSGSESDLEKSIFNIIKNCNQKVAVSLFASNIARIYTIVNI
CCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ATKLGRKVAILGKSLIRIIQAAQDSGYLQDIPEFININQANKLPNDQVLLLCTGCQGEEL
HHHHCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHH
AATAKLANNSHPFTKLDNGDTIIFSSKIIPGNEKRIYSVFNKFVNMGVNVITEFMEHVHV
HHHHHHCCCCCCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCC
SGHPSKSEVSTMYSLVRPKLSIPVHGEYIHMHEHAKVAKQCNVEKAIIVHPGDVISLTKK
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCCCEEEECHH
QKINSVKAGYFGVDGNFLHHPKGNVISMRKKMRDAGIIIITLVLNNKKELLKEPRIFAPG
HHCCCCCCCEEECCCCEEECCCCCCHHHHHHHCCCCEEEEEEEECCCHHHHHCCCCCCCC
VLDHSNSQAILKKVSSKISSELYSRKINNIRQYVENTVFNALKYDIKNKPFIEVQLEYIN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure
MNTDDLLFTPLGGVGQIGMNVNLYHLNGKWIIIDFGAGFADDNMPGIDMIVADISFIKKN
CCCCCEEEECCCCCCEECCEEEEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHC
RKNLLGIVLTHAHEDHIGGIQYLWNDLQCPIYATKFTAALLQAKLKEYPFRINITEIDIT
CCCEEEEEEEECCCCCCCCHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCEEEEEEEEEEE
KKLNLGPFTLEFINLTHSIPEMNAIALHTEKGIVVHTGDWKLDDNPIIGPVSNTQRLKEL
EECCCCCEEEEEEEHHCCCCCCCEEEEEECCCEEEECCCEEECCCCEECCCCCHHHHHHC
GDEGVLALVCDSTNIFTKNKSGSESDLEKSIFNIIKNCNQKVAVSLFASNIARIYTIVNI
CCCCEEEEEECCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ATKLGRKVAILGKSLIRIIQAAQDSGYLQDIPEFININQANKLPNDQVLLLCTGCQGEEL
HHHHCCEEEHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHH
AATAKLANNSHPFTKLDNGDTIIFSSKIIPGNEKRIYSVFNKFVNMGVNVITEFMEHVHV
HHHHHHCCCCCCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCC
SGHPSKSEVSTMYSLVRPKLSIPVHGEYIHMHEHAKVAKQCNVEKAIIVHPGDVISLTKK
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCCCEEEECHH
QKINSVKAGYFGVDGNFLHHPKGNVISMRKKMRDAGIIIITLVLNNKKELLKEPRIFAPG
HHCCCCCCCEEECCCCEEECCCCCCHHHHHHHCCCCEEEEEEEECCCHHHHHCCCCCCCC
VLDHSNSQAILKKVSSKISSELYSRKINNIRQYVENTVFNALKYDIKNKPFIEVQLEYIN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA