Click here to switch to the map view.

The map label for this gene is hslV [H]

Identifier: 88658351

GI number: 88658351

Start: 1020843

End: 1021412

Strand: Direct

Name: hslV [H]

Synonym: ECH_0996

Alternate gene names: 88658351

Gene position: 1020843-1021412 (Clockwise)

Preceding gene: 88657676

Following gene: 88657724

Centisome position: 86.79

GC content: 34.56

Gene sequence:

>570_bases
ATGGAACACAAAGACAACAGTACAATGTATGGAACCACTATTTTATGCATTCGTAGAGGCAATAAAGTTATAATTGCAGG
AGATGGGCAAGTATCGTTAGGACACACTGTAATAAAAAATTCAGCAAAAAAAATAAAACGTTTAGCCAATGATACAGTAA
TTACAGGGTTTGCGGGTGCAACAGCAGATGCCTTTACCCTTTTTGAAAGATTAGAAAGTAAATTAGAGAAGCACCCTGGA
CAATTACTCCGTGCATGCGTAGAATTAGCAAAAGATTGGAGAATGGATAGGTATTTGCGTAGACTAGAAGCAATGATGAT
TGTAGCAGATAAATCAGTATCTTTAATAATATCAGGCAACGGAGATGTATTAGAACCAGAAAATGGAATCGCAGCTATTG
GATCAGGAGGTAACTATGCTTTAGCAGCAGCAAAAGCCCTATGTGAATCTAATGATCAGTTTTCTCAAAACATGACTTTG
GAATATATAATTACCACTGCAATGAAAATAGCTTCTGAAATATGTATTTATACAAACAACAATATTATTATGGAAAAAAT
AGAGGATTAA

Upstream 100 bases:

>100_bases
GTATTTAACAATTTACATTTACTTCTCAAGTGGTATAGATAAAGCCATATATGTTTAAAAAAGTTGCCGTATATTTAAGT
TATAAGCAGGAGTTTAAATA

Downstream 100 bases:

>100_bases
AATGTTTGTTACACCAAATAATAAACTCAAATTGAATAATGATACAACAAATAATATAAATGATGAACAAGCTAGTAGTG
AAGTACTAAATAGTGAAAAC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MEHKDNSTMYGTTILCIRRGNKVIIAGDGQVSLGHTVIKNSAKKIKRLANDTVITGFAGATADAFTLFERLESKLEKHPG
QLLRACVELAKDWRMDRYLRRLEAMMIVADKSVSLIISGNGDVLEPENGIAAIGSGGNYALAAAKALCESNDQFSQNMTL
EYIITTAMKIASEICIYTNNNIIMEKIED

Sequences:

>Translated_189_residues
MEHKDNSTMYGTTILCIRRGNKVIIAGDGQVSLGHTVIKNSAKKIKRLANDTVITGFAGATADAFTLFERLESKLEKHPG
QLLRACVELAKDWRMDRYLRRLEAMMIVADKSVSLIISGNGDVLEPENGIAAIGSGGNYALAAAKALCESNDQFSQNMTL
EYIITTAMKIASEICIYTNNNIIMEKIED
>Mature_189_residues
MEHKDNSTMYGTTILCIRRGNKVIIAGDGQVSLGHTVIKNSAKKIKRLANDTVITGFAGATADAFTLFERLESKLEKHPG
QLLRACVELAKDWRMDRYLRRLEAMMIVADKSVSLIISGNGDVLEPENGIAAIGSGGNYALAAAKALCESNDQFSQNMTL
EYIITTAMKIASEICIYTNNNIIMEKIED

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=176, Percent_Identity=57.3863636363636, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.- [C]

Molecular weight: Translated: 20718; Mature: 20718

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKDNSTMYGTTILCIRRGNKVIIAGDGQVSLGHTVIKNSAKKIKRLANDTVITGFAGA
CCCCCCCEEEEEEEEEEECCCEEEEECCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCC
TADAFTLFERLESKLEKHPGQLLRACVELAKDWRMDRYLRRLEAMMIVADKSVSLIISGN
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEECC
GDVLEPENGIAAIGSGGNYALAAAKALCESNDQFSQNMTLEYIITTAMKIASEICIYTNN
CCEECCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHEEEEECC
NIIMEKIED
CEEEEECCC
>Mature Secondary Structure
MEHKDNSTMYGTTILCIRRGNKVIIAGDGQVSLGHTVIKNSAKKIKRLANDTVITGFAGA
CCCCCCCEEEEEEEEEEECCCEEEEECCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCC
TADAFTLFERLESKLEKHPGQLLRACVELAKDWRMDRYLRRLEAMMIVADKSVSLIISGN
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCEEEEEECC
GDVLEPENGIAAIGSGGNYALAAAKALCESNDQFSQNMTLEYIITTAMKIASEICIYTNN
CCEECCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHEEEEECC
NIIMEKIED
CEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA