Click here to switch to the map view.

The map label for this gene is ctrA [H]

Identifier: 88658273

GI number: 88658273

Start: 1038108

End: 1038905

Strand: Reverse

Name: ctrA [H]

Synonym: ECH_1012

Alternate gene names: 88658273

Gene position: 1038905-1038108 (Counterclockwise)

Preceding gene: 88657833

Following gene: 88657845

Centisome position: 88.32

GC content: 33.83

Gene sequence:

>798_bases
ATGCGTATATTATTAATAGAAGATGATATTGCATGTGCAAAGGCAGTAGAAGCTTCTTTATCTTCAGAAGGGCATTTTTG
TGAGACTATGACTTCTGCGCAGGATTGTTATGGTAGTATCATTCCGAAGAATGATGACTATGATGTAGTGATATTAGATA
TACATTTTCCTGGAAAAATAGATGGATATGATATTTTAGTGAAACTGCGAGAGTCTGGTATCAAAGTTCCAGTTCTTATA
TTATCATGTATTTCATCAGTATCACATAAAGTAAAAGGTTTATATTATGGTGCAGATGATTATGTGACTAAACCTTTTCA
TAAAAGTGAATTACTTGCGAGAATAAAAGCTATTGTGCGCCGTACTAGGGGACATCCTGAATCAATAGTACGTGTTGGAA
ATATTGCAATCAATCTTGATCATAAGTGTGTTGAATGTAATGGTGAAATAGTGCATTTAACTAAAAAGGAGTATGGGATG
ATAGAGTTGTTATCATCTAGGTTAGGTACTGTTCTTACAAAAGAAATGTTTTTATCTCACCTATATAGGGAGTTAGATGA
ACCTTCTGATGATAAAATTATAGATGTGTTTATGTGTAAGCTTCGTAAGAAACTTAAAGTCGCTAATAATGGGAAAAACT
ACATAGAAACTGTTTGGGGACGTGGTTATGTATTAAAAGAGTGTGTTGACGAAGATGAAAGTGATGATAGAGGAGGATAT
AGATGGGATCATGGTGGTGCCAATGTTGACTCAATTTATGGTCAAGAGGAAGATAAAAAGTATGTTGAGGAAGCATAA

Upstream 100 bases:

>100_bases
GATGAAATGTTTAGTTGTTATAGGGTGATTATGTCTTTAGATTAGTGCTAAGTGCTTTATGTGTTAAGTTTGTTAATTAT
TGGGTTTTTAGAGGTATTTT

Downstream 100 bases:

>100_bases
TATAGTTGAGAGGCATTTTACTACATGATACAATGAACAAAGGTATTATATATACTTTGTAGGTGGAGGAAATTTACGTG
CCTGTATTTGTACATGATTG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRILLIEDDIACAKAVEASLSSEGHFCETMTSAQDCYGSIIPKNDDYDVVILDIHFPGKIDGYDILVKLRESGIKVPVLI
LSCISSVSHKVKGLYYGADDYVTKPFHKSELLARIKAIVRRTRGHPESIVRVGNIAINLDHKCVECNGEIVHLTKKEYGM
IELLSSRLGTVLTKEMFLSHLYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKECVDEDESDDRGGY
RWDHGGANVDSIYGQEEDKKYVEEA

Sequences:

>Translated_265_residues
MRILLIEDDIACAKAVEASLSSEGHFCETMTSAQDCYGSIIPKNDDYDVVILDIHFPGKIDGYDILVKLRESGIKVPVLI
LSCISSVSHKVKGLYYGADDYVTKPFHKSELLARIKAIVRRTRGHPESIVRVGNIAINLDHKCVECNGEIVHLTKKEYGM
IELLSSRLGTVLTKEMFLSHLYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKECVDEDESDDRGGY
RWDHGGANVDSIYGQEEDKKYVEEA
>Mature_265_residues
MRILLIEDDIACAKAVEASLSSEGHFCETMTSAQDCYGSIIPKNDDYDVVILDIHFPGKIDGYDILVKLRESGIKVPVLI
LSCISSVSHKVKGLYYGADDYVTKPFHKSELLARIKAIVRRTRGHPESIVRVGNIAINLDHKCVECNGEIVHLTKKEYGM
IELLSSRLGTVLTKEMFLSHLYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKECVDEDESDDRGGY
RWDHGGANVDSIYGQEEDKKYVEEA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=37.4449339207048, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=35.1111111111111, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=32.5991189427313, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.4410480349345, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=31.1965811965812, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=26.9911504424779, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=28.6995515695067, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=27.4336283185841, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=28.7610619469027, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=27.8260869565217, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29938; Mature: 29938

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDIACAKAVEASLSSEGHFCETMTSAQDCYGSIIPKNDDYDVVILDIHFPGKI
CEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
DGYDILVKLRESGIKVPVLILSCISSVSHKVKGLYYGADDYVTKPFHKSELLARIKAIVR
CCHHEEEEEHHCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCHHHHHHHHHHHHH
RTRGHPESIVRVGNIAINLDHKCVECNGEIVHLTKKEYGMIELLSSRLGTVLTKEMFLSH
HHCCCHHHHEEECCEEEECCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKECVDEDESDDRGGY
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCE
RWDHGGANVDSIYGQEEDKKYVEEA
EECCCCCCHHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MRILLIEDDIACAKAVEASLSSEGHFCETMTSAQDCYGSIIPKNDDYDVVILDIHFPGKI
CEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
DGYDILVKLRESGIKVPVLILSCISSVSHKVKGLYYGADDYVTKPFHKSELLARIKAIVR
CCHHEEEEEHHCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCHHHHHHHHHHHHH
RTRGHPESIVRVGNIAINLDHKCVECNGEIVHLTKKEYGMIELLSSRLGTVLTKEMFLSH
HHCCCHHHHEEECCEEEECCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LYRELDEPSDDKIIDVFMCKLRKKLKVANNGKNYIETVWGRGYVLKECVDEDESDDRGGY
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCE
RWDHGGANVDSIYGQEEDKKYVEEA
EECCCCCCHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA