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The map label for this gene is fusA [H]

Identifier: 88658102

GI number: 88658102

Start: 984464

End: 986536

Strand: Reverse

Name: fusA [H]

Synonym: ECH_0961

Alternate gene names: 88658102

Gene position: 986536-984464 (Counterclockwise)

Preceding gene: 88658498

Following gene: 88658644

Centisome position: 83.87

GC content: 35.21

Gene sequence:

>2073_bases
GTGAGCATAGATAACGAGTTATCTAAGTGTAGGAATATAGGGATTATGGCGCATATAGATGCCGGGAAGACTACTACAAC
TGAGCGTATACTTTTTTATACTGGAAAACAAAATAGAATTGGTGAGGTTCATGAAGGTGCTGCATCTATGGATTGGATGG
AGCAAGAAAAGGAGAGAGGAATTACAATAACTTCTGCAGCTACTACATGTTTTTGGAATGGTCATAGGATTAACATTATT
GATACTCCTGGTCATGTTGATTTTACTATAGAGGTAGAAAGGTCTTTACGTGTTTTAGATGGTGCTGTTGCTGTCTTTGA
TGGAGTTGCGGGTGTTGAACCTCAATCAGAAACAGTGTGGCGTCAAGCTGATAAATATAATGTACCCAGAATTTGTTTTA
TGAATAAAATGGATAGGATGGGAGCAGACTTTTATCGGTGTGTTGATATGGTTGTTGAACGTCTGGGTGCTACTCCATTA
GTATTGCAATTACCAATAGGAATTGAGAAAGATTTTGTTGGTGTTGTTGATTTATTGGAGATGAGATCAATTATATGGGA
TGAAGATTCTCTAGGAGCAAGTTTTCATTATGGAGAAATCCCTAAAGATATGCTTGATAAAGCTCAAGAATATAGAAATA
AGCTTCTGGAAAGTGCAGTTGAGCTTAATGATGAAGCAATGAATTTGTATTTTGAAGGTAAGGAAATATCTGTTTCTTTA
TTGAAAAGTTGTATTCGTGCAGGAGTAATTCAGTCAAAATTTGTACCTGTTTTGTGTGGTTCTGCGTTTAAAAACAGGGG
AGTACAGCCATTACTAGATGCTGTTGTTGATTTTTTGCCTGCGCCTAATGATATTCCTATGATGGAAGCTCTCGATGTAA
AGACTTCTAATACTATAAACATTAAGTCTTCTATTGATGGTAAATTTGTTGCGTTAGCTTTTAAAGTAATGACTGATAAA
TTTGTTGGTAGTTTGACTTTTATAAGAATTTACTCAGGAAGGTTATCAAGTAAGACTACAGTACTGAATGCAGTTAAAAA
TTCTACAGAATCTATAGGTAGAATTTTATTAATGCATGCTAACAATAGAGAGGATATCACTGAAGCAAAAGCTGGTGATA
TTGTTGCTTTAGCTGGGCTTAAAAAGACGGTAACTGGTGATACATTATGTACTTTAGACCAACCTATAATTTTAGAGCGC
ATGGAATTTCCTGAACCAGTTATGGAGATTGCAGTAGAACCAAAATCTACAGCGGATCAAGAAAAAATGGGTATAGCTTT
AAGTAGATTAGTTGCAGAAGATCCATCACTTGGTATGTGTGTAAATCCTGAAAGTGGACAAACTATCTTGAAAGGAATGG
GTGAATTGCATCTTGAAGTTATTGTAGATAGAATGCGTCGTGAGTTTAATGTTGAAGCTAATATAGGTGCTCCGCAAGTT
GCTTACAGAGAAACTATTACTAAATCTGTTGAAATTGAATATATTCATAAAAAGCAAACAGGTGGTGCTGGGCAGTTTGC
AAAGGTGAATATATTATTTGAACCATTACCTCCTGGTTCTGGTTTCCAATTTGAAAGTAAAATTACTGGTGGTGCAATAC
CTAAAGAATATATACCAGGTGTTCAAAATGGGTTAGAAAATATTAGAGGAAGTGGTATGTTAGCAGGGTTTCCTGTTATT
GATTTTAAAGCAACATTAGTTGATGGTGCATTTCATGAAGTAGATTCTAGTCCATTAGCATTTGAGTTAGCTGCAAAAGG
TGCTTTTAGAGATATGGTGAACAAAGCTGGTGCAATATTACTTGAACCTATTATGAAAGTTGAGATAATAACTCCTGATG
AGTACATGGGGGATGTTATAGGTGATATTAATAGTAGGAGAGGTAGGGTTGCTGAAATGCAAGATCGTCACAATACTAAA
GTAATATTAGCATTTATTCCTTTGGCAAAAATGTTTGGTTATGTTAAAGATTTGCGCTCTATGTCTCAGGGTAGAGCACA
ATATAGCATGTATTTTTCTTGTTATGAACAAGTACCTGATAATATAGTGGCAAACGAGATAAAAACTAAATAA

Upstream 100 bases:

>100_bases
GTGCGTATAAAATGAGGGAAGAGAAGTATAAGATGGCAGAAGCAAATAAAGCGTTTTCTCATTTTCGCTTTAATTAATAT
TAATTTTTGGAGATAAGTTT

Downstream 100 bases:

>100_bases
TAGGTGTAATGTTATGGTAGAAGAAAGGAAACCACATATAAATGTAGGGACAATAGGGCATGTTGATCATGGTAAGACAA
CATTAACAGCAGCGTTAACA

Product: elongation factor G

Products: NA

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MSIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERGITITSAATTCFWNGHRINII
DTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFMNKMDRMGADFYRCVDMVVERLGATPL
VLQLPIGIEKDFVGVVDLLEMRSIIWDEDSLGASFHYGEIPKDMLDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSL
LKSCIRAGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPMMEALDVKTSNTINIKSSIDGKFVALAFKVMTDK
FVGSLTFIRIYSGRLSSKTTVLNAVKNSTESIGRILLMHANNREDITEAKAGDIVALAGLKKTVTGDTLCTLDQPIILER
MEFPEPVMEIAVEPKSTADQEKMGIALSRLVAEDPSLGMCVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQV
AYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPGVQNGLENIRGSGMLAGFPVI
DFKATLVDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAILLEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTK
VILAFIPLAKMFGYVKDLRSMSQGRAQYSMYFSCYEQVPDNIVANEIKTK

Sequences:

>Translated_690_residues
MSIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERGITITSAATTCFWNGHRINII
DTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFMNKMDRMGADFYRCVDMVVERLGATPL
VLQLPIGIEKDFVGVVDLLEMRSIIWDEDSLGASFHYGEIPKDMLDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSL
LKSCIRAGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPMMEALDVKTSNTINIKSSIDGKFVALAFKVMTDK
FVGSLTFIRIYSGRLSSKTTVLNAVKNSTESIGRILLMHANNREDITEAKAGDIVALAGLKKTVTGDTLCTLDQPIILER
MEFPEPVMEIAVEPKSTADQEKMGIALSRLVAEDPSLGMCVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQV
AYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPGVQNGLENIRGSGMLAGFPVI
DFKATLVDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAILLEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTK
VILAFIPLAKMFGYVKDLRSMSQGRAQYSMYFSCYEQVPDNIVANEIKTK
>Mature_689_residues
SIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERGITITSAATTCFWNGHRINIID
TPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRICFMNKMDRMGADFYRCVDMVVERLGATPLV
LQLPIGIEKDFVGVVDLLEMRSIIWDEDSLGASFHYGEIPKDMLDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSLL
KSCIRAGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPMMEALDVKTSNTINIKSSIDGKFVALAFKVMTDKF
VGSLTFIRIYSGRLSSKTTVLNAVKNSTESIGRILLMHANNREDITEAKAGDIVALAGLKKTVTGDTLCTLDQPIILERM
EFPEPVMEIAVEPKSTADQEKMGIALSRLVAEDPSLGMCVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQVA
YRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPGVQNGLENIRGSGMLAGFPVID
FKATLVDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAILLEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTKV
ILAFIPLAKMFGYVKDLRSMSQGRAQYSMYFSCYEQVPDNIVANEIKTK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=689, Percent_Identity=42.2351233671988, Blast_Score=533, Evalue=1e-151,
Organism=Homo sapiens, GI19923640, Length=713, Percent_Identity=40.5329593267882, Blast_Score=503, Evalue=1e-142,
Organism=Homo sapiens, GI25306283, Length=452, Percent_Identity=44.6902654867257, Blast_Score=351, Evalue=1e-96,
Organism=Homo sapiens, GI25306287, Length=292, Percent_Identity=53.0821917808219, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI4503483, Length=427, Percent_Identity=25.5269320843091, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI94966754, Length=136, Percent_Identity=38.9705882352941, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI157426893, Length=153, Percent_Identity=35.2941176470588, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310132016, Length=117, Percent_Identity=37.6068376068376, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI310110807, Length=117, Percent_Identity=37.6068376068376, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI310123363, Length=117, Percent_Identity=37.6068376068376, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI94966752, Length=64, Percent_Identity=48.4375, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1789738, Length=702, Percent_Identity=56.5527065527066, Blast_Score=801, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=495, Percent_Identity=29.4949494949495, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI48994988, Length=163, Percent_Identity=42.3312883435583, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788922, Length=181, Percent_Identity=35.9116022099448, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=683, Percent_Identity=40.1171303074671, Blast_Score=502, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17556745, Length=721, Percent_Identity=29.8196948682386, Blast_Score=309, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI17506493, Length=416, Percent_Identity=26.9230769230769, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17557151, Length=136, Percent_Identity=40.4411764705882, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=136, Percent_Identity=32.3529411764706, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988811, Length=136, Percent_Identity=32.3529411764706, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=680, Percent_Identity=41.3235294117647, Blast_Score=533, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6322359, Length=784, Percent_Identity=33.2908163265306, Blast_Score=378, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324707, Length=822, Percent_Identity=24.9391727493917, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320593, Length=822, Percent_Identity=24.9391727493917, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323320, Length=175, Percent_Identity=32.5714285714286, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324166, Length=154, Percent_Identity=35.0649350649351, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24582462, Length=694, Percent_Identity=41.3544668587896, Blast_Score=541, Evalue=1e-154,
Organism=Drosophila melanogaster, GI221458488, Length=721, Percent_Identity=34.2579750346741, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24585711, Length=571, Percent_Identity=26.2697022767075, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24585713, Length=571, Percent_Identity=26.2697022767075, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24585709, Length=571, Percent_Identity=26.2697022767075, Blast_Score=143, Evalue=5e-34,
Organism=Drosophila melanogaster, GI78706572, Length=137, Percent_Identity=37.956204379562, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574573, Length=169, Percent_Identity=33.7278106508876, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 76244; Mature: 76113

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERG
CCCCHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHCC
ITITSAATTCFWNGHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVW
EEEEECCEEEEECCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHH
RQADKYNVPRICFMNKMDRMGADFYRCVDMVVERLGATPLVLQLPIGIEKDFVGVVDLLE
HHHCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHH
MRSIIWDEDSLGASFHYGEIPKDMLDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSL
HHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
LKSCIRAGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPMMEALDVKTSNTIN
HHHHHHHCHHHHCCHHHHHCCHHHCCCCHHHHHHHHHHCCCCCCCCCHHEEECCCCCEEE
IKSSIDGKFVALAFKVMTDKFVGSLTFIRIYSGRLSSKTTVLNAVKNSTESIGRILLMHA
EECCCCCEEEEHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCEEEEEEC
NNREDITEAKAGDIVALAGLKKTVTGDTLCTLDQPIILERMEFPEPVMEIAVEPKSTADQ
CCCCHHHHCCCCCEEEECCCCHHCCCCEEEECCCCHHHHHHCCCCHHHHEECCCCCCCCH
EKMGIALSRLVAEDPSLGMCVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQV
HHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCH
AYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPG
HHHHHHHCCEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCEEECCCCCCCCCHHHCCH
VQNGLENIRGSGMLAGFPVIDFKATLVDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAIL
HHHHHHHHCCCCEEECCCEEEEEHHHCCCHHHHCCCCCCEEEEHHHHHHHHHHHHCCHHE
LEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTKVILAFIPLAKMFGYVKDLRS
ECCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
MSQGRAQYSMYFSCYEQVPDNIVANEIKTK
HHHCCHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
SIDNELSKCRNIGIMAHIDAGKTTTTERILFYTGKQNRIGEVHEGAASMDWMEQEKERG
CCCHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHCC
ITITSAATTCFWNGHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVW
EEEEECCEEEEECCEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHH
RQADKYNVPRICFMNKMDRMGADFYRCVDMVVERLGATPLVLQLPIGIEKDFVGVVDLLE
HHHCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHH
MRSIIWDEDSLGASFHYGEIPKDMLDKAQEYRNKLLESAVELNDEAMNLYFEGKEISVSL
HHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
LKSCIRAGVIQSKFVPVLCGSAFKNRGVQPLLDAVVDFLPAPNDIPMMEALDVKTSNTIN
HHHHHHHCHHHHCCHHHHHCCHHHCCCCHHHHHHHHHHCCCCCCCCCHHEEECCCCCEEE
IKSSIDGKFVALAFKVMTDKFVGSLTFIRIYSGRLSSKTTVLNAVKNSTESIGRILLMHA
EECCCCCEEEEHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCEEEEEEC
NNREDITEAKAGDIVALAGLKKTVTGDTLCTLDQPIILERMEFPEPVMEIAVEPKSTADQ
CCCCHHHHCCCCCEEEECCCCHHCCCCEEEECCCCHHHHHHCCCCHHHHEECCCCCCCCH
EKMGIALSRLVAEDPSLGMCVNPESGQTILKGMGELHLEVIVDRMRREFNVEANIGAPQV
HHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCH
AYRETITKSVEIEYIHKKQTGGAGQFAKVNILFEPLPPGSGFQFESKITGGAIPKEYIPG
HHHHHHHCCEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCEEECCCCCCCCCHHHCCH
VQNGLENIRGSGMLAGFPVIDFKATLVDGAFHEVDSSPLAFELAAKGAFRDMVNKAGAIL
HHHHHHHHCCCCEEECCCEEEEEHHHCCCHHHHCCCCCCEEEEHHHHHHHHHHHHCCHHE
LEPIMKVEIITPDEYMGDVIGDINSRRGRVAEMQDRHNTKVILAFIPLAKMFGYVKDLRS
ECCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
MSQGRAQYSMYFSCYEQVPDNIVANEIKTK
HHHCCHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA