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The map label for this gene is argC

Identifier: 88657913

GI number: 88657913

Start: 1042055

End: 1043095

Strand: Reverse

Name: argC

Synonym: ECH_1017

Alternate gene names: 88657913

Gene position: 1043095-1042055 (Counterclockwise)

Preceding gene: 88658111

Following gene: 88658186

Centisome position: 88.68

GC content: 33.14

Gene sequence:

>1041_bases
ATGAGTTATCAAGTATCAGTTGCTGTAGTTGGGGCTACAGGTTATGTAGGGGTAGAGTTAGTACGTTTGTTATTATCTCA
TCCTATGGTTAAGATAAAGTATTTATGTGCAACTCAATCTAGTGGAAAGTTACTTTCTTCTAATTATTTCCACATTTCGC
AGGATGATATATCCGTTAATATTTCGTCTTTTGATGATATTGACTTATCTAAAGTAGATGTGGTTTTTTTGTGCTTACCT
CATGGTACATCAAGTGAAGTTGTAAGAAAAATTCATGATGTAGTAAGAATTATAGATTTATCAGCTGATTTTAGAATTAA
GGATGCTGAAGTATATAAACAATGGTATGGCTCACATTGTTGTCCAGATCTTGTAAGAGATTTTGTATACGGGTTAACGG
AGATATATTGGGAAGATATTCAAAGGTCAAGGTTTATAGCTTGTCCAGGATGTTATCCTACCTCTGTGCTAATACCATTA
TTTCCATTGTTAAGACTTTGTTTAATAAAAAGTCAGGGTATAATAGTTGATGCTAAATCAGGTGTGAGTGGTGCTGGTAG
GTCTGTAAAGCAGGATAAGTTGTTCTGTGAAGTTTATGATGTTATTAAATCGTATAAAATTTCAGACCATAGACATATTC
CTGAAATAGAGCAAGAGCTTTGTTTTGCTGCCTGTAGAGAAGACATTAATTTACAATTTGTGCCTAATTTAATTCCTGTC
AAAAGAGGTATGATGTCTAGTATATACCTTGAGTTAGAAGAAGGCGTATCGCTTACTGATGTCCGTGAAGCATTGTTGCT
TTTTTACAAAGATTCATCTTTTGTTTTTATTGATGAAGAGAAAGCTATGACAACTAGGTCTGTTGTGGGTACGAATTATT
GTTATTTAGGTGTTTTTCCTGGAAGGGTACCTAACACGATTATTATCATGTCTGTTATAGATAATTTATTAAAAGGTGCA
GCTGGTCAAGCAGTGCAAAATTTTAATGTTATGATGTCTTATGATGAGAAAATTGCTTTGTCAAATATTCCTTATTTTTA
A

Upstream 100 bases:

>100_bases
GTGGGTTCTTGACTAGAGATTCGCGTGTTGTTGAACGTAAAAAGTATGGTCAACATAAGGCTAGAAAAAGTTGTCAATTC
TCTAAAAGATAACCTATTAA

Downstream 100 bases:

>100_bases
ATATTTACTTTAAAGTATATAAATTTAAGATCTGTTTTTTAGACAGATAGTCTGTGTGATTGATAGAAGTATAGAGTTTG
ATTTATTTTGATGTATTGGT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSYQVSVAVVGATGYVGVELVRLLLSHPMVKIKYLCATQSSGKLLSSNYFHISQDDISVNISSFDDIDLSKVDVVFLCLP
HGTSSEVVRKIHDVVRIIDLSADFRIKDAEVYKQWYGSHCCPDLVRDFVYGLTEIYWEDIQRSRFIACPGCYPTSVLIPL
FPLLRLCLIKSQGIIVDAKSGVSGAGRSVKQDKLFCEVYDVIKSYKISDHRHIPEIEQELCFAACREDINLQFVPNLIPV
KRGMMSSIYLELEEGVSLTDVREALLLFYKDSSFVFIDEEKAMTTRSVVGTNYCYLGVFPGRVPNTIIIMSVIDNLLKGA
AGQAVQNFNVMMSYDEKIALSNIPYF

Sequences:

>Translated_346_residues
MSYQVSVAVVGATGYVGVELVRLLLSHPMVKIKYLCATQSSGKLLSSNYFHISQDDISVNISSFDDIDLSKVDVVFLCLP
HGTSSEVVRKIHDVVRIIDLSADFRIKDAEVYKQWYGSHCCPDLVRDFVYGLTEIYWEDIQRSRFIACPGCYPTSVLIPL
FPLLRLCLIKSQGIIVDAKSGVSGAGRSVKQDKLFCEVYDVIKSYKISDHRHIPEIEQELCFAACREDINLQFVPNLIPV
KRGMMSSIYLELEEGVSLTDVREALLLFYKDSSFVFIDEEKAMTTRSVVGTNYCYLGVFPGRVPNTIIIMSVIDNLLKGA
AGQAVQNFNVMMSYDEKIALSNIPYF
>Mature_345_residues
SYQVSVAVVGATGYVGVELVRLLLSHPMVKIKYLCATQSSGKLLSSNYFHISQDDISVNISSFDDIDLSKVDVVFLCLPH
GTSSEVVRKIHDVVRIIDLSADFRIKDAEVYKQWYGSHCCPDLVRDFVYGLTEIYWEDIQRSRFIACPGCYPTSVLIPLF
PLLRLCLIKSQGIIVDAKSGVSGAGRSVKQDKLFCEVYDVIKSYKISDHRHIPEIEQELCFAACREDINLQFVPNLIPVK
RGMMSSIYLELEEGVSLTDVREALLLFYKDSSFVFIDEEKAMTTRSVVGTNYCYLGVFPGRVPNTIIIMSVIDNLLKGAA
GQAVQNFNVMMSYDEKIALSNIPYF

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=340, Percent_Identity=33.8235294117647, Blast_Score=167, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6320913, Length=343, Percent_Identity=28.2798833819242, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_EHRCR (Q2GFI0)

Other databases:

- EMBL:   CP000236
- RefSeq:   YP_507803.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q2GFI0
- SMR:   Q2GFI0
- STRING:   Q2GFI0
- GeneID:   3927783
- GenomeReviews:   CP000236_GR
- KEGG:   ech:ECH_1017
- TIGR:   ECH_1017
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q2GFI0
- ProtClustDB:   PRK00436
- BioCyc:   ECHA205920:ECH_1017-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38872; Mature: 38740

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVSVAVVGATGYVGVELVRLLLSHPMVKIKYLCATQSSGKLLSSNYFHISQDDISVN
CCEEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEECCCEEEECCCEEEE
ISSFDDIDLSKVDVVFLCLPHGTSSEVVRKIHDVVRIIDLSADFRIKDAEVYKQWYGSHC
ECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCC
CPDLVRDFVYGLTEIYWEDIQRSRFIACPGCYPTSVLIPLFPLLRLCLIKSQGIIVDAKS
CHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
GVSGAGRSVKQDKLFCEVYDVIKSYKISDHRHIPEIEQELCFAACREDINLQFVPNLIPV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCHHHH
KRGMMSSIYLELEEGVSLTDVREALLLFYKDSSFVFIDEEKAMTTRSVVGTNYCYLGVFP
HHHHHHHHHEEHHCCCCHHHHHHHHEEEEECCEEEEEECCHHHHHHHHHCCCEEEEEECC
GRVPNTIIIMSVIDNLLKGAAGQAVQNFNVMMSYDEKIALSNIPYF
CCCCCCEEHHHHHHHHHCCCCCHHHHCCEEEEECCCEEECCCCCCC
>Mature Secondary Structure 
SYQVSVAVVGATGYVGVELVRLLLSHPMVKIKYLCATQSSGKLLSSNYFHISQDDISVN
CEEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEECCCEEEECCCEEEE
ISSFDDIDLSKVDVVFLCLPHGTSSEVVRKIHDVVRIIDLSADFRIKDAEVYKQWYGSHC
ECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHCCCCC
CPDLVRDFVYGLTEIYWEDIQRSRFIACPGCYPTSVLIPLFPLLRLCLIKSQGIIVDAKS
CHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCC
GVSGAGRSVKQDKLFCEVYDVIKSYKISDHRHIPEIEQELCFAACREDINLQFVPNLIPV
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCHHHH
KRGMMSSIYLELEEGVSLTDVREALLLFYKDSSFVFIDEEKAMTTRSVVGTNYCYLGVFP
HHHHHHHHHEEHHCCCCHHHHHHHHEEEEECCEEEEEECCHHHHHHHHHCCCEEEEEECC
GRVPNTIIIMSVIDNLLKGAAGQAVQNFNVMMSYDEKIALSNIPYF
CCCCCCEEHHHHHHHHHCCCCCHHHHCCEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA