Click here to switch to the map view.

The map label for this gene is znuA [H]

Identifier: 88657604

GI number: 88657604

Start: 860387

End: 861235

Strand: Direct

Name: znuA [H]

Synonym: ECH_0842

Alternate gene names: 88657604

Gene position: 860387-861235 (Clockwise)

Preceding gene: 88658201

Following gene: 88657853

Centisome position: 73.15

GC content: 28.62

Gene sequence:

>849_bases
TTGCTCTTTTATATATTATTACATCCTACTATAGGATATTCTGTACCAAGAATTATAGCAACTATAAACCCAATATATTC
ACTAGTTAATGCAGTCACTAATGGTATAACAAAGCCAGTTCTTTTAATCAATGAACCAGTATCAATACATGATTACATGT
TAAAACCATCTGACAAAAGGAAATTAAAGGATAGTGATATAATATTTTACGTAGATGATCACCTTGAAACTTTTATAAAC
AAAATACAAAACAAAACGTTAGTCAAACTCTCAGAGGTAATAGAATTATTACCATCAAGATACGATTCTAACTTTTCTTA
TAAAATTCACACAACATCAAATGATCTACACATTTGGTTAAGCCCAGAAAATGCAAAAAATATAGTCAATCAAATAAAAA
CGGTTTTATGTAATGCAGATCCAGAAAATGCAGAAAAGTATTCCAATAATGCAAACTTAGCATTGACACAAATTACAAAA
CAAACAGAAAAGATAAAAAGTACCCTAAGCTCTGTCAAGACAAAGCCTTACATAGTTACACATGATGCATATCAATATTT
TGAAAAATACTTCGGATTAAATTTTATAGCAGCTCTTTCTTCAAGCCATGATACAAATATCAGCGTAAAAAGGCTAATGC
ATATCAAAAAAATTATTACTCAACACAAAATAAAATGTATTTTTTCTGAATCTTCAAATGATAAAGTCAAGAATTTATTT
CTAAAATACCAAGTAAAATTTCAAATACTTGACCCCATAGGCAACACCCTAGCAGCAAAAGATAATGCATATTTTGACAT
TATGCAAAATATTGCCAATAACTTTCTACAGTGTCTATCAGAGGAATAA

Upstream 100 bases:

>100_bases
AAAGATTTTCAACATTTATAATATAGTTATTGACGTACTTTTTATCATATGCAAGAATTTCACTTTTATTTAATAACTTA
TGAAACATACAATCCTTCTC

Downstream 100 bases:

>100_bases
CACCACATAACGCATCTAATATAATAAGCTTCTATAGACTACTGAAGATACACATAAGAACATATTGTATAATATATATA
AAAAGGGTATATTTACAGAC

Product: putative cation ABC transporter, periplasmic cation-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLFYILLHPTIGYSVPRIIATINPIYSLVNAVTNGITKPVLLINEPVSIHDYMLKPSDKRKLKDSDIIFYVDDHLETFIN
KIQNKTLVKLSEVIELLPSRYDSNFSYKIHTTSNDLHIWLSPENAKNIVNQIKTVLCNADPENAEKYSNNANLALTQITK
QTEKIKSTLSSVKTKPYIVTHDAYQYFEKYFGLNFIAALSSSHDTNISVKRLMHIKKIITQHKIKCIFSESSNDKVKNLF
LKYQVKFQILDPIGNTLAAKDNAYFDIMQNIANNFLQCLSEE

Sequences:

>Translated_282_residues
MLFYILLHPTIGYSVPRIIATINPIYSLVNAVTNGITKPVLLINEPVSIHDYMLKPSDKRKLKDSDIIFYVDDHLETFIN
KIQNKTLVKLSEVIELLPSRYDSNFSYKIHTTSNDLHIWLSPENAKNIVNQIKTVLCNADPENAEKYSNNANLALTQITK
QTEKIKSTLSSVKTKPYIVTHDAYQYFEKYFGLNFIAALSSSHDTNISVKRLMHIKKIITQHKIKCIFSESSNDKVKNLF
LKYQVKFQILDPIGNTLAAKDNAYFDIMQNIANNFLQCLSEE
>Mature_282_residues
MLFYILLHPTIGYSVPRIIATINPIYSLVNAVTNGITKPVLLINEPVSIHDYMLKPSDKRKLKDSDIIFYVDDHLETFIN
KIQNKTLVKLSEVIELLPSRYDSNFSYKIHTTSNDLHIWLSPENAKNIVNQIKTVLCNADPENAEKYSNNANLALTQITK
QTEKIKSTLSSVKTKPYIVTHDAYQYFEKYFGLNFIAALSSSHDTNISVKRLMHIKKIITQHKIKCIFSESSNDKVKNLF
LKYQVKFQILDPIGNTLAAKDNAYFDIMQNIANNFLQCLSEE

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=280, Percent_Identity=26.7857142857143, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32338; Mature: 32338

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFYILLHPTIGYSVPRIIATINPIYSLVNAVTNGITKPVLLINEPVSIHDYMLKPSDKR
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHEEECCCHHC
KLKDSDIIFYVDDHLETFINKIQNKTLVKLSEVIELLPSRYDSNFSYKIHTTSNDLHIWL
CCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
SPENAKNIVNQIKTVLCNADPENAEKYSNNANLALTQITKQTEKIKSTLSSVKTKPYIVT
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEE
HDAYQYFEKYFGLNFIAALSSSHDTNISVKRLMHIKKIITQHKIKCIFSESSNDKVKNLF
HHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHEE
LKYQVKFQILDPIGNTLAAKDNAYFDIMQNIANNFLQCLSEE
EEEEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLFYILLHPTIGYSVPRIIATINPIYSLVNAVTNGITKPVLLINEPVSIHDYMLKPSDKR
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHEEECCCHHC
KLKDSDIIFYVDDHLETFINKIQNKTLVKLSEVIELLPSRYDSNFSYKIHTTSNDLHIWL
CCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
SPENAKNIVNQIKTVLCNADPENAEKYSNNANLALTQITKQTEKIKSTLSSVKTKPYIVT
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEE
HDAYQYFEKYFGLNFIAALSSSHDTNISVKRLMHIKKIITQHKIKCIFSESSNDKVKNLF
HHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHEE
LKYQVKFQILDPIGNTLAAKDNAYFDIMQNIANNFLQCLSEE
EEEEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA