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The map label for this gene is ctrA [H]

Identifier: 88608551

GI number: 88608551

Start: 199190

End: 199987

Strand: Direct

Name: ctrA [H]

Synonym: NSE_0234

Alternate gene names: 88608551

Gene position: 199190-199987 (Clockwise)

Preceding gene: 88608235

Following gene: 88607961

Centisome position: 23.19

GC content: 42.11

Gene sequence:

>798_bases
ATGCGTATATTAGTAGTCGATGACGAACAGAAGGTAACAGATTACGTAAAGAGTATCATTACCTCTGTTGGGTATGTTTG
TGACACAGCTTCTTGTTGCCGTGATGCTTCAGCACTGATTAATTCCAGCAAGGGCGATTATCAGTATGATCTTATTATTC
TGGATAGGGTTCTCCCAGACGGGGATGGCTTAGATATGATCTTAAACTTGCGTTGCAAGAACATAAAAACTCCTGTGATC
TTTTTTTCTGCTCTCTCGTCTTATGAGAACAGGATTAAGGCTTTCGATTTTGGTGCAGATGATTTCATCGCAAAGAGTGA
GCTACATAAGGGTGAGTTTCTTGCTCGCATAAGGGCTGTTCTCAGAAGGTGCTTCAGTCACCACTTTTCGAAATTTAAAC
TTGGTAACATGTTGGTGGACTTTCATATGCAGGTCTGTAAGATGCGTGGTAAGGTTGTGCAACTGACAAACAAGGAATAC
TCAATGCTAGAGTTGATGTGTCTTCATGGTAGAGGGGCTATCATATCTAAGGACAAGTTTATAAGCCATCTTTATTCTAA
TAATGAGCCGACAGAGCAAAAGATTATCGATGTTTTTGCTTGTAAACTACGCAGCAAGCTGGCTGCCTATAACGACGGTG
TGAGTTACATAGAGACGGTTTGGGGAAGGGGATACACGTTAAATGAGAATGTTCCTCCGATAAGAAGCAGCGTAAAAAAA
TCTAAAGCTATTTCCGATGGTGATGACGCTGCTGTGAGGACTGAGGCTGGGCATGAGCTCCAGAAGAGTACCACCTAA

Upstream 100 bases:

>100_bases
GTGGTCTTTTGTGTTTTATGGTGTGAGTAGTTCCCGATCCCAGGGGTATTTTTCTTGTGCCCCATTTGATTTGATTTTTT
TGCTGTAGGGTGGAGTTGAG

Downstream 100 bases:

>100_bases
GCGAGAGGATCGTAGCACTAATGCTGTCGACTAGGAGTAGATTTTCTCCTTTTCTCGTGCCACAGGTAGATGTCGCGTCC
ATCTTGGTTGAGTGCTCTTA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRILVVDDEQKVTDYVKSIITSVGYVCDTASCCRDASALINSSKGDYQYDLIILDRVLPDGDGLDMILNLRCKNIKTPVI
FFSALSSYENRIKAFDFGADDFIAKSELHKGEFLARIRAVLRRCFSHHFSKFKLGNMLVDFHMQVCKMRGKVVQLTNKEY
SMLELMCLHGRGAIISKDKFISHLYSNNEPTEQKIIDVFACKLRSKLAAYNDGVSYIETVWGRGYTLNENVPPIRSSVKK
SKAISDGDDAAVRTEAGHELQKSTT

Sequences:

>Translated_265_residues
MRILVVDDEQKVTDYVKSIITSVGYVCDTASCCRDASALINSSKGDYQYDLIILDRVLPDGDGLDMILNLRCKNIKTPVI
FFSALSSYENRIKAFDFGADDFIAKSELHKGEFLARIRAVLRRCFSHHFSKFKLGNMLVDFHMQVCKMRGKVVQLTNKEY
SMLELMCLHGRGAIISKDKFISHLYSNNEPTEQKIIDVFACKLRSKLAAYNDGVSYIETVWGRGYTLNENVPPIRSSVKK
SKAISDGDDAAVRTEAGHELQKSTT
>Mature_265_residues
MRILVVDDEQKVTDYVKSIITSVGYVCDTASCCRDASALINSSKGDYQYDLIILDRVLPDGDGLDMILNLRCKNIKTPVI
FFSALSSYENRIKAFDFGADDFIAKSELHKGEFLARIRAVLRRCFSHHFSKFKLGNMLVDFHMQVCKMRGKVVQLTNKEY
SMLELMCLHGRGAIISKDKFISHLYSNNEPTEQKIIDVFACKLRSKLAAYNDGVSYIETVWGRGYTLNENVPPIRSSVKK
SKAISDGDDAAVRTEAGHELQKSTT

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.3478260869565, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.4159292035398, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=29.6943231441048, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=31.4893617021277, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=32.1739130434783, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=28.0172413793103, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=27.3913043478261, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367329, Length=237, Percent_Identity=27.4261603375527, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=28.8888888888889, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=26.431718061674, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=27.1929824561404, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=27.7310924369748, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29873; Mature: 29873

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVDDEQKVTDYVKSIITSVGYVCDTASCCRDASALINSSKGDYQYDLIILDRVLPD
CEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCC
GDGLDMILNLRCKNIKTPVIFFSALSSYENRIKAFDFGADDFIAKSELHKGEFLARIRAV
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHH
LRRCFSHHFSKFKLGNMLVDFHMQVCKMRGKVVQLTNKEYSMLELMCLHGRGAIISKDKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCEEEHHHH
ISHLYSNNEPTEQKIIDVFACKLRSKLAAYNDGVSYIETVWGRGYTLNENVPPIRSSVKK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCHHHHHHHH
SKAISDGDDAAVRTEAGHELQKSTT
HHCCCCCCCCEEECCCCCHHHHCCC
>Mature Secondary Structure
MRILVVDDEQKVTDYVKSIITSVGYVCDTASCCRDASALINSSKGDYQYDLIILDRVLPD
CEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCC
GDGLDMILNLRCKNIKTPVIFFSALSSYENRIKAFDFGADDFIAKSELHKGEFLARIRAV
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHH
LRRCFSHHFSKFKLGNMLVDFHMQVCKMRGKVVQLTNKEYSMLELMCLHGRGAIISKDKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCEEEHHHH
ISHLYSNNEPTEQKIIDVFACKLRSKLAAYNDGVSYIETVWGRGYTLNENVPPIRSSVKK
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCHHHHHHHH
SKAISDGDDAAVRTEAGHELQKSTT
HHCCCCCCCCEEECCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA