Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 88607820

GI number: 88607820

Start: 337008

End: 337925

Strand: Direct

Name: era [H]

Synonym: APH_0350

Alternate gene names: 88607820

Gene position: 337008-337925 (Clockwise)

Preceding gene: 88607548

Following gene: 88607261

Centisome position: 22.91

GC content: 41.39

Gene sequence:

>918_bases
GTGTTTTCTAATTTTGGTGAGCGTGTGGAAATCGAGAATACGGGATTGATGAAATGTTCTTTAGTTGCTGTTGTTGGTAT
GACCAATGCTGGCAAATCAACCTTAATTAACAAGTTAGTTGGGTTTAAGGCCTCTATAGTTACTAATAAAGTGCACACAA
CCCGAGTGAAAATGAACTCTGTGCTGAATGAAGGTAATGTACAGCTGGTGTTTACTGATACTCCAGGGATTTTTTCTCCT
AAGACGAAGCTTGAGAAGTTTATTGTCAAGAACGCGTGGATGTCGATGAAGGGTGCGGACATGGTTATTCTAGTGCTCGA
TGCGAAGCGACGGATCTGCGTACATGTTGAAAAGATCATTAAAAGGTTGCAACGAGATAACGTTGCTTCTATTGCAGTAA
TTAACAAGATGGATCTTCTTGATGAGGGTGAATTAGCGACTTTTGCAGAGCGTGTACAGTTATTGCACAAATTTGATAGG
GTTTTTACAGTTTCTTCGCTGTACGGAACTGGGGTACGTGATTTGATTGACTATTTGCAAGAATCAGCATGTGATGGGCC
GTGGTTATATCCGGAAGAATATCGTACTGATGCAACTTTAGAATTCTTTGCTGCAGAGATAACTAGGGAAAAGTTATACC
TAGCGCTCAGGCAAGAGCTGCCTTATTCCTTATCTGTAGTGACGGAGCAGATAGAGGAAAAGGGCGATAGCATTATAATC
AAGCAAGTTATTTACGTGATGAAGGAGAGCCAAAAAACCATTGTTGTCGGAGCAGATGCTGCACTGATTAAGAGTGTGAG
CACTGCTGCTCGGTACGAGCTAAGCGCTATGCTCAATAAAAAGGTGCACCTTTACCTATTTGTAAAAGTGCGTAAGTTTT
GGCAAGATCATCTGGAAGAATGTGTTGGATACTCATGA

Upstream 100 bases:

>100_bases
TAATGAATCTTCTGAAGGGGAAGTAGCCCGTTATTTTGGGATGTGACACGTGTGATATGCTTGCTACGTCATAGAGCGGG
TGTATGGGAGTTTGCTTTTT

Downstream 100 bases:

>100_bases
TTCACAGAGGAAGCGATTTGCGTATTTATCTTGCGGGTTAATAACCGCTGTGTAGGAATATGGGTACATATAATGTTGGA
CTCTTTGCTTGTTTTTGACA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MFSNFGERVEIENTGLMKCSLVAVVGMTNAGKSTLINKLVGFKASIVTNKVHTTRVKMNSVLNEGNVQLVFTDTPGIFSP
KTKLEKFIVKNAWMSMKGADMVILVLDAKRRICVHVEKIIKRLQRDNVASIAVINKMDLLDEGELATFAERVQLLHKFDR
VFTVSSLYGTGVRDLIDYLQESACDGPWLYPEEYRTDATLEFFAAEITREKLYLALRQELPYSLSVVTEQIEEKGDSIII
KQVIYVMKESQKTIVVGADAALIKSVSTAARYELSAMLNKKVHLYLFVKVRKFWQDHLEECVGYS

Sequences:

>Translated_305_residues
MFSNFGERVEIENTGLMKCSLVAVVGMTNAGKSTLINKLVGFKASIVTNKVHTTRVKMNSVLNEGNVQLVFTDTPGIFSP
KTKLEKFIVKNAWMSMKGADMVILVLDAKRRICVHVEKIIKRLQRDNVASIAVINKMDLLDEGELATFAERVQLLHKFDR
VFTVSSLYGTGVRDLIDYLQESACDGPWLYPEEYRTDATLEFFAAEITREKLYLALRQELPYSLSVVTEQIEEKGDSIII
KQVIYVMKESQKTIVVGADAALIKSVSTAARYELSAMLNKKVHLYLFVKVRKFWQDHLEECVGYS
>Mature_305_residues
MFSNFGERVEIENTGLMKCSLVAVVGMTNAGKSTLINKLVGFKASIVTNKVHTTRVKMNSVLNEGNVQLVFTDTPGIFSP
KTKLEKFIVKNAWMSMKGADMVILVLDAKRRICVHVEKIIKRLQRDNVASIAVINKMDLLDEGELATFAERVQLLHKFDR
VFTVSSLYGTGVRDLIDYLQESACDGPWLYPEEYRTDATLEFFAAEITREKLYLALRQELPYSLSVVTEQIEEKGDSIII
KQVIYVMKESQKTIVVGADAALIKSVSTAARYELSAMLNKKVHLYLFVKVRKFWQDHLEECVGYS

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=332, Percent_Identity=29.8192771084337, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1788919, Length=284, Percent_Identity=33.8028169014084, Blast_Score=147, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24646434, Length=252, Percent_Identity=29.3650793650794, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34506; Mature: 34506

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSNFGERVEIENTGLMKCSLVAVVGMTNAGKSTLINKLVGFKASIVTNKVHTTRVKMNS
CCCCCCCEEEECCCCCHHEEHEEEEECCCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
VLNEGNVQLVFTDTPGIFSPKTKLEKFIVKNAWMSMKGADMVILVLDAKRRICVHVEKII
HHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHH
KRLQRDNVASIAVINKMDLLDEGELATFAERVQLLHKFDRVFTVSSLYGTGVRDLIDYLQ
HHHHHCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ESACDGPWLYPEEYRTDATLEFFAAEITREKLYLALRQELPYSLSVVTEQIEEKGDSIII
HHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEHH
KQVIYVMKESQKTIVVGADAALIKSVSTAARYELSAMLNKKVHLYLFVKVRKFWQDHLEE
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
CVGYS
HCCCC
>Mature Secondary Structure
MFSNFGERVEIENTGLMKCSLVAVVGMTNAGKSTLINKLVGFKASIVTNKVHTTRVKMNS
CCCCCCCEEEECCCCCHHEEHEEEEECCCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
VLNEGNVQLVFTDTPGIFSPKTKLEKFIVKNAWMSMKGADMVILVLDAKRRICVHVEKII
HHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHH
KRLQRDNVASIAVINKMDLLDEGELATFAERVQLLHKFDRVFTVSSLYGTGVRDLIDYLQ
HHHHHCCCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ESACDGPWLYPEEYRTDATLEFFAAEITREKLYLALRQELPYSLSVVTEQIEEKGDSIII
HHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEHH
KQVIYVMKESQKTIVVGADAALIKSVSTAARYELSAMLNKKVHLYLFVKVRKFWQDHLEE
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHH
CVGYS
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA