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The map label for this gene is ubiA [H]

Identifier: 88607763

GI number: 88607763

Start: 296533

End: 297411

Strand: Direct

Name: ubiA [H]

Synonym: APH_0310

Alternate gene names: 88607763

Gene position: 296533-297411 (Clockwise)

Preceding gene: 88606770

Following gene: 88607004

Centisome position: 20.15

GC content: 40.96

Gene sequence:

>879_bases
ATGTTTAGCAGGGTAAAGAAGGTATTTGGCGCTCTGGTTCCGTATTCTCAGTTGATAAGGCTGCATAGCTGCGAGATATC
TTTGCTAGCAACATTTCCTACTTGTGCAAGTATCGTTCTCGCTTCTAACAGCTTATACAGCGTACTAAAATTGTTTGTTC
TTGTAGCGATTGGAGCTTTGGTAGTGAGATCTGCTGGGTGTATCATCAATGATATCTTTGATAGGAATATAGACATCCAT
GTACACAGAACAAAATCCAGGCCAATAGCCTGCGGGCGTTTGAAAGTGCGTGAGGGGTTATGTGCCTTAGCTGTCCTGCT
GTGCATTGCCGGTGTGATTTTATTGTTTACAAATAAATTGTCTCTATATCTAAGCATAATCTGCTTTTGCGGCGTTGTAC
TTTATCCACTGATGAAGAGATTTTTTTCATATCCACAGTTTGTGCTTGGCATTGTGTGGAATTTTGGAATTCTGATAGGT
TCCGCAATGGCTGCAAATGAAGTAAAGTTCGGTTCTATACTTTTGTACATAGGATGCATATTCTGGACTACAGCTTTTGA
CACAATATATGCACATCAGGACAAGGTAGACGATGCTAGGTTAGGTTTGGGTAGTACTGCATTAAAGTTTGGAGACAATA
CCGGACTATATGTGAAGCGTCTGTATATCTTGACAATAACGATGTGGGTATGTGCTGGAGTCGTATCATCACTCAGCTGG
CCATACTATGTCTTTATTTTGAAAAGTGCAGGAGTATTCTACTACCAGTGGAGGAAGACAGATTTTGACAATCCGGCTAG
ATGCATGTATATGTTCAAGACGAACATATACGCAGGGATCCTATTGTTTCTAGGCGTGTGTTTGGGTCGTATAGTTTAG

Upstream 100 bases:

>100_bases
TAGAGGTTTATGTTATAGTGGCAGGTTTCTTGCAAAAATATTCTCAGGTGTTTTTTGAATTCACCGTTTATATTTGCTGT
GTGTGTTGTGGAGGAAATAT

Downstream 100 bases:

>100_bases
GTGCCTGTTGTGCTTTGTGCATGCAACAATTAGGAAGTATATCTGCTAAGCGTTTTAAGTCGTGCATGGGGAGGTTTGCT
ACGGGTGTCACGGTTGTCAC

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFSRVKKVFGALVPYSQLIRLHSCEISLLATFPTCASIVLASNSLYSVLKLFVLVAIGALVVRSAGCIINDIFDRNIDIH
VHRTKSRPIACGRLKVREGLCALAVLLCIAGVILLFTNKLSLYLSIICFCGVVLYPLMKRFFSYPQFVLGIVWNFGILIG
SAMAANEVKFGSILLYIGCIFWTTAFDTIYAHQDKVDDARLGLGSTALKFGDNTGLYVKRLYILTITMWVCAGVVSSLSW
PYYVFILKSAGVFYYQWRKTDFDNPARCMYMFKTNIYAGILLFLGVCLGRIV

Sequences:

>Translated_292_residues
MFSRVKKVFGALVPYSQLIRLHSCEISLLATFPTCASIVLASNSLYSVLKLFVLVAIGALVVRSAGCIINDIFDRNIDIH
VHRTKSRPIACGRLKVREGLCALAVLLCIAGVILLFTNKLSLYLSIICFCGVVLYPLMKRFFSYPQFVLGIVWNFGILIG
SAMAANEVKFGSILLYIGCIFWTTAFDTIYAHQDKVDDARLGLGSTALKFGDNTGLYVKRLYILTITMWVCAGVVSSLSW
PYYVFILKSAGVFYYQWRKTDFDNPARCMYMFKTNIYAGILLFLGVCLGRIV
>Mature_292_residues
MFSRVKKVFGALVPYSQLIRLHSCEISLLATFPTCASIVLASNSLYSVLKLFVLVAIGALVVRSAGCIINDIFDRNIDIH
VHRTKSRPIACGRLKVREGLCALAVLLCIAGVILLFTNKLSLYLSIICFCGVVLYPLMKRFFSYPQFVLGIVWNFGILIG
SAMAANEVKFGSILLYIGCIFWTTAFDTIYAHQDKVDDARLGLGSTALKFGDNTGLYVKRLYILTITMWVCAGVVSSLSW
PYYVFILKSAGVFYYQWRKTDFDNPARCMYMFKTNIYAGILLFLGVCLGRIV

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=282, Percent_Identity=35.4609929078014, Blast_Score=157, Evalue=8e-39,
Organism=Escherichia coli, GI1790473, Length=277, Percent_Identity=32.4909747292419, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553718, Length=277, Percent_Identity=37.5451263537906, Blast_Score=177, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI32565247, Length=278, Percent_Identity=38.8489208633094, Blast_Score=172, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17553720, Length=335, Percent_Identity=33.134328358209, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI32565245, Length=140, Percent_Identity=40.7142857142857, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32565243, Length=139, Percent_Identity=40.2877697841727, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324370, Length=287, Percent_Identity=34.4947735191638, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21355567, Length=290, Percent_Identity=34.8275862068965, Blast_Score=181, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32615; Mature: 32615

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRVKKVFGALVPYSQLIRLHSCEISLLATFPTCASIVLASNSLYSVLKLFVLVAIGAL
CHHHHHHHHHHHCCHHHHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VVRSAGCIINDIFDRNIDIHVHRTKSRPIACGRLKVREGLCALAVLLCIAGVILLFTNKL
HHHHCCHHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYLSIICFCGVVLYPLMKRFFSYPQFVLGIVWNFGILIGSAMAANEVKFGSILLYIGCI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FWTTAFDTIYAHQDKVDDARLGLGSTALKFGDNTGLYVKRLYILTITMWVCAGVVSSLSW
HHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PYYVFILKSAGVFYYQWRKTDFDNPARCMYMFKTNIYAGILLFLGVCLGRIV
CCEEEEEECCCEEEEEEECCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFSRVKKVFGALVPYSQLIRLHSCEISLLATFPTCASIVLASNSLYSVLKLFVLVAIGAL
CHHHHHHHHHHHCCHHHHHHHHCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VVRSAGCIINDIFDRNIDIHVHRTKSRPIACGRLKVREGLCALAVLLCIAGVILLFTNKL
HHHHCCHHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYLSIICFCGVVLYPLMKRFFSYPQFVLGIVWNFGILIGSAMAANEVKFGSILLYIGCI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FWTTAFDTIYAHQDKVDDARLGLGSTALKFGDNTGLYVKRLYILTITMWVCAGVVSSLSW
HHHHHHHHHHHCCCCCCHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PYYVFILKSAGVFYYQWRKTDFDNPARCMYMFKTNIYAGILLFLGVCLGRIV
CCEEEEEECCCEEEEEEECCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA