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The map label for this gene is fabD [H]

Identifier: 88607175

GI number: 88607175

Start: 97971

End: 98930

Strand: Direct

Name: fabD [H]

Synonym: APH_0092

Alternate gene names: 88607175

Gene position: 97971-98930 (Clockwise)

Preceding gene: 88607899

Following gene: 88607927

Centisome position: 6.66

GC content: 45.83

Gene sequence:

>960_bases
GTGTCTACTGTGTTTATGTTTCCCGGACAAGGTTCACAGTTTGTTGGTATGGGAAAAGAGGTATATGAGAACTTTGCTGT
AGCGCGGGAAGTGTTTCACGAAGTTGATGAAACTCTTGGTCGGAATCTATCTGATATTATCTTCAATGGCCCAGAAGAGG
TTCTGACATCAACTTGTAATGCACAATTGGCACTTATGACTGTTTCCATAGCGGTGGTACGTGCAGTGGAACATGTTGTT
GGCATGCCTTTGGATAGGTATGCTAGGTATGTTATAGGGCACTCTGTTGGTGAGTATACGGCACTGTGTGCTGCGGGTGT
TATTGATTTACCTACTGCAGTTAGGATTCTTGACGTTCGTAGCAGGGCTATGGGCAAGGCTTCAGAAATGTGTCAGGGGG
GAATGTCTGCGCTCATAGGTGGTTGTGTAGAGGACGTTGAGGCTGTTGTGCAGGCTGCTTCTAAATTTGGTGTGTGTGAA
ATAGCAAATGACAATTGTAATGGGCAAATAGTAGTTAGTGGTACGAATGAAGCTCTTGAAGCGTTGCCGGAGCTTGTTGT
AGGGACTGCTGTAAGGCGTGTAATAAGGCTGCGTGTGAGTGGCCCGTTTCATTCTTCTCTTATGCATCCTGCGTATGAAG
AGCTCAGGGATTTTGTAAGTACGTTGGAGCTCAAAGCACCGAAGATTGGTATAGTTTATAATGTTTCTGCCTCAGAGCAT
GAGGATTGTGATGTCATCAAAGATTTAATGGCACGGCAAGTGGTTAGCAGGGTTAGGTGGCGTGAGAGCATAGAGTATCT
TCTGGGGCATGGGTGTTCTGAATTTGTAGAAGCGGGTCCTGGCGAGGTTTTAACCGGTTTGTTACGTCGCATAGATAGGA
CTGTGCGTTGTGTTAGTGTTTGTGCAGTAGATGCGATGCGAGAGTTATCGCAATATGCTGAAGTTCGTGAGTTTTGCTAG

Upstream 100 bases:

>100_bases
TACCGCGCCATTTTTCTTGAGCTTTTATAATAATTTTGACTACTACGGTTGTGTTGAGTAATAATTGCCATATTGCATGT
AGCCTCTAGGGGGTGGAGTT

Downstream 100 bases:

>100_bases
AGTGTCCTTGGGTAATATGTTCATAACTTTTGAGGGAATAGATGGGTGTGGTAAGACCACGCAGTCTATTTTACTAGCGA
AGTATATGTCTGATCTGTAC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSTVFMFPGQGSQFVGMGKEVYENFAVAREVFHEVDETLGRNLSDIIFNGPEEVLTSTCNAQLALMTVSIAVVRAVEHVV
GMPLDRYARYVIGHSVGEYTALCAAGVIDLPTAVRILDVRSRAMGKASEMCQGGMSALIGGCVEDVEAVVQAASKFGVCE
IANDNCNGQIVVSGTNEALEALPELVVGTAVRRVIRLRVSGPFHSSLMHPAYEELRDFVSTLELKAPKIGIVYNVSASEH
EDCDVIKDLMARQVVSRVRWRESIEYLLGHGCSEFVEAGPGEVLTGLLRRIDRTVRCVSVCAVDAMRELSQYAEVREFC

Sequences:

>Translated_319_residues
MSTVFMFPGQGSQFVGMGKEVYENFAVAREVFHEVDETLGRNLSDIIFNGPEEVLTSTCNAQLALMTVSIAVVRAVEHVV
GMPLDRYARYVIGHSVGEYTALCAAGVIDLPTAVRILDVRSRAMGKASEMCQGGMSALIGGCVEDVEAVVQAASKFGVCE
IANDNCNGQIVVSGTNEALEALPELVVGTAVRRVIRLRVSGPFHSSLMHPAYEELRDFVSTLELKAPKIGIVYNVSASEH
EDCDVIKDLMARQVVSRVRWRESIEYLLGHGCSEFVEAGPGEVLTGLLRRIDRTVRCVSVCAVDAMRELSQYAEVREFC
>Mature_318_residues
STVFMFPGQGSQFVGMGKEVYENFAVAREVFHEVDETLGRNLSDIIFNGPEEVLTSTCNAQLALMTVSIAVVRAVEHVVG
MPLDRYARYVIGHSVGEYTALCAAGVIDLPTAVRILDVRSRAMGKASEMCQGGMSALIGGCVEDVEAVVQAASKFGVCEI
ANDNCNGQIVVSGTNEALEALPELVVGTAVRRVIRLRVSGPFHSSLMHPAYEELRDFVSTLELKAPKIGIVYNVSASEHE
DCDVIKDLMARQVVSRVRWRESIEYLLGHGCSEFVEAGPGEVLTGLLRRIDRTVRCVSVCAVDAMRELSQYAEVREFC

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=319, Percent_Identity=31.974921630094, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=35.1851851851852, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=302, Percent_Identity=35.0993377483444, Blast_Score=184, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71984332, Length=300, Percent_Identity=30, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24665753, Length=311, Percent_Identity=31.1897106109325, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34756; Mature: 34625

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVFMFPGQGSQFVGMGKEVYENFAVAREVFHEVDETLGRNLSDIIFNGPEEVLTSTCN
CCEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCC
AQLALMTVSIAVVRAVEHVVGMPLDRYARYVIGHSVGEYTALCAAGVIDLPTAVRILDVR
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SRAMGKASEMCQGGMSALIGGCVEDVEAVVQAASKFGVCEIANDNCNGQIVVSGTNEALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCHHHHH
ALPELVVGTAVRRVIRLRVSGPFHSSLMHPAYEELRDFVSTLELKAPKIGIVYNVSASEH
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
EDCDVIKDLMARQVVSRVRWRESIEYLLGHGCSEFVEAGPGEVLTGLLRRIDRTVRCVSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
CAVDAMRELSQYAEVREFC
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVFMFPGQGSQFVGMGKEVYENFAVAREVFHEVDETLGRNLSDIIFNGPEEVLTSTCN
CEEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCC
AQLALMTVSIAVVRAVEHVVGMPLDRYARYVIGHSVGEYTALCAAGVIDLPTAVRILDVR
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SRAMGKASEMCQGGMSALIGGCVEDVEAVVQAASKFGVCEIANDNCNGQIVVSGTNEALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCHHHHH
ALPELVVGTAVRRVIRLRVSGPFHSSLMHPAYEELRDFVSTLELKAPKIGIVYNVSASEH
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
EDCDVIKDLMARQVVSRVRWRESIEYLLGHGCSEFVEAGPGEVLTGLLRRIDRTVRCVSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
CAVDAMRELSQYAEVREFC
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]