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The map label for this gene is nrdR

Identifier: 88606966

GI number: 88606966

Start: 48447

End: 48908

Strand: Direct

Name: nrdR

Synonym: APH_0047

Alternate gene names: 88606966

Gene position: 48447-48908 (Clockwise)

Preceding gene: 88607852

Following gene: 88607541

Centisome position: 3.29

GC content: 39.61

Gene sequence:

>462_bases
ATGAAATGTCCGTTTTGTAACAGTGCGGATACAAGAGTGAAGAACTCTAGGCACTCCGATGATAATATGTCTGTGAGAAG
ACGTAGGTTGTGTGAAGTTTGCAACTCTAGGTTCACGACTCTTGAGGAGTTGTTGCTTAAGCCTATCATGGTTCTGAAAA
AAGATGGAAGAATGGAGCCTTTTGACAAGCAGAAGTTACTTACATCTATTATGTTGGCTACAAACAAGCGTCCAGTTACC
CATGCACAAATAAATATGGTGCTAAGCAAGATACTGTATAAGTTTGAGTCGGTGAAAGAGGATGTTATTCCTGCTAGGGT
GATAGGAGAGATAGTAAAAAACAACCTTTTGGTTTTGGATAAGGTTGCATACATCAGGTTTGTTTCCGTGTATATGGACT
TTAGCGATGCGGATGACTTCTGTAGTTTAGTAGAAAAGATTAAAGAGGGATCCGATAAGTGA

Upstream 100 bases:

>100_bases
TCCTACGTTGCCCAATTATAAGGTCTATGATATGAAACACAACTGCTAACTGGTTATCTGTGGGTAGTTGGCAGAAATTC
TTAGTGAAAATTGAGCTTTT

Downstream 100 bases:

>100_bases
CATAAGTACGGATATTTTTTCTTGAGTTCGTGTGGAGCTTATGTTAGCCTCAAGAGTGGTTTTGGGGGCATAGCTCAGTT
GGTAGAGCATCTGTTTTGCA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MKCPFCNSADTRVKNSRHSDDNMSVRRRRLCEVCNSRFTTLEELLLKPIMVLKKDGRMEPFDKQKLLTSIMLATNKRPVT
HAQINMVLSKILYKFESVKEDVIPARVIGEIVKNNLLVLDKVAYIRFVSVYMDFSDADDFCSLVEKIKEGSDK

Sequences:

>Translated_153_residues
MKCPFCNSADTRVKNSRHSDDNMSVRRRRLCEVCNSRFTTLEELLLKPIMVLKKDGRMEPFDKQKLLTSIMLATNKRPVT
HAQINMVLSKILYKFESVKEDVIPARVIGEIVKNNLLVLDKVAYIRFVSVYMDFSDADDFCSLVEKIKEGSDK
>Mature_153_residues
MKCPFCNSADTRVKNSRHSDDNMSVRRRRLCEVCNSRFTTLEELLLKPIMVLKKDGRMEPFDKQKLLTSIMLATNKRPVT
HAQINMVLSKILYKFESVKEDVIPARVIGEIVKNNLLVLDKVAYIRFVSVYMDFSDADDFCSLVEKIKEGSDK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=40.9395973154362, Blast_Score=119, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ANAPZ (Q2GLS0)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_504681.1
- STRING:   Q2GLS0
- GeneID:   3930031
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0047
- NMPDR:   fig|212042.5.peg.44
- TIGR:   APH_0047
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   APHA212042:APH_0047-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17665; Mature: 17665

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCNSADTRVKNSRHSDDNMSVRRRRLCEVCNSRFTTLEELLLKPIMVLKKDGRMEP
CCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FDKQKLLTSIMLATNKRPVTHAQINMVLSKILYKFESVKEDVIPARVIGEIVKNNLLVLD
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KVAYIRFVSVYMDFSDADDFCSLVEKIKEGSDK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKCPFCNSADTRVKNSRHSDDNMSVRRRRLCEVCNSRFTTLEELLLKPIMVLKKDGRMEP
CCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FDKQKLLTSIMLATNKRPVTHAQINMVLSKILYKFESVKEDVIPARVIGEIVKNNLLVLD
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KVAYIRFVSVYMDFSDADDFCSLVEKIKEGSDK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA