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The map label for this gene is nuoC [H]

Identifier: 88606931

GI number: 88606931

Start: 541308

End: 541874

Strand: Direct

Name: nuoC [H]

Synonym: APH_0521

Alternate gene names: 88606931

Gene position: 541308-541874 (Clockwise)

Preceding gene: 88607775

Following gene: 88606856

Centisome position: 36.79

GC content: 44.44

Gene sequence:

>567_bases
ATGTCTTTAGATATTGAGCCTGTTGCTAGCTCGCATATACAGGAACTGTTGCAGACTGATATTGTGTTGCGCCAAGATGG
TGTGCTGCAGTGTTATCTTGAGGCGCAGAGTATACGGGATAATCTTATTACTCTGCGGGATGATCCCAAGACTAAGCTCA
GGGTGCTGACTGATATTTTTGCGGTCGACTATCACAACAAGAAATCTAGATTTGAAGTAGTCTACATGCTTCTTAGTCTT
GTTTATAACATACGGGTGTGCTGTAAGGTTGCGCTGACTGAGGGAAGTATTATACCTTCTGTAACTTCAGTTTTTGGATC
CGCGGGGTGGTTTGAGCGCGAAGTTTACGATATGTATGGCATCGAGTTTAGTGATCATCCTGATCTGAGGCGTATTCTCA
CAGACTACGGGTTTCGAGGTCACCCAATGCTAAAGGACTTTCCGCTCACGGGTTACGAAGAGATACGATATGACTTCCGT
AAAGGGAAGGTGGCATATCAGCCGGTGGATTTGCAGCAAAACTTTAGGTTATTCAATTCAATGTCGCCATGGAAAGGCTA
CAAGTAA

Upstream 100 bases:

>100_bases
GTGCCTGGATGCCCTCCGACAGCGGAAGCCTTGTTATATGGTTTGCTGTGTTTACAGCAGAAGATCCTTCGCAACGGTCA
AGGAACTTGGAGGGCGTAGA

Downstream 100 bases:

>100_bases
TTAATGTATAACCCACTATTGCGGCAGTATAGGGTATGGCATTCTCGAATTGTTTATGCGCCATTGATACCTTATTCGCA
GTGTTGTTGCAGATAACTCA

Product: NADH dehydrogenase I, C subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSLDIEPVASSHIQELLQTDIVLRQDGVLQCYLEAQSIRDNLITLRDDPKTKLRVLTDIFAVDYHNKKSRFEVVYMLLSL
VYNIRVCCKVALTEGSIIPSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFR
KGKVAYQPVDLQQNFRLFNSMSPWKGYK

Sequences:

>Translated_188_residues
MSLDIEPVASSHIQELLQTDIVLRQDGVLQCYLEAQSIRDNLITLRDDPKTKLRVLTDIFAVDYHNKKSRFEVVYMLLSL
VYNIRVCCKVALTEGSIIPSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFR
KGKVAYQPVDLQQNFRLFNSMSPWKGYK
>Mature_187_residues
SLDIEPVASSHIQELLQTDIVLRQDGVLQCYLEAQSIRDNLITLRDDPKTKLRVLTDIFAVDYHNKKSRFEVVYMLLSLV
YNIRVCCKVALTEGSIIPSVTSVFGSAGWFEREVYDMYGIEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFRK
GKVAYQPVDLQQNFRLFNSMSPWKGYK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=170, Percent_Identity=45.2941176470588, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI145693162, Length=94, Percent_Identity=40.4255319148936, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=143, Percent_Identity=48.951048951049, Blast_Score=150, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI32563621, Length=159, Percent_Identity=45.2830188679245, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24656494, Length=159, Percent_Identity=45.9119496855346, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21919; Mature: 21788

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDIEPVASSHIQELLQTDIVLRQDGVLQCYLEAQSIRDNLITLRDDPKTKLRVLTDIF
CCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEEEHHHHHCCEEEECCCCHHHHHHHHHHH
AVDYHNKKSRFEVVYMLLSLVYNIRVCCKVALTEGSIIPSVTSVFGSAGWFEREVYDMYG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCCCHHHHHHHHHC
IEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFRKGKVAYQPVDLQQNFRLFNS
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHCC
MSPWKGYK
CCCCCCCC
>Mature Secondary Structure 
SLDIEPVASSHIQELLQTDIVLRQDGVLQCYLEAQSIRDNLITLRDDPKTKLRVLTDIF
CCCCCHHHHHHHHHHHHHHHEECCCCEEEEEEEHHHHHCCEEEECCCCHHHHHHHHHHH
AVDYHNKKSRFEVVYMLLSLVYNIRVCCKVALTEGSIIPSVTSVFGSAGWFEREVYDMYG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHCCCCCHHHHHHHHHC
IEFSDHPDLRRILTDYGFRGHPMLKDFPLTGYEEIRYDFRKGKVAYQPVDLQQNFRLFNS
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHCC
MSPWKGYK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA