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The map label for this gene is obgE

Identifier: 88606806

GI number: 88606806

Start: 716645

End: 717703

Strand: Reverse

Name: obgE

Synonym: APH_0694

Alternate gene names: 88606806

Gene position: 717703-716645 (Counterclockwise)

Preceding gene: 88607824

Following gene: 88607506

Centisome position: 48.78

GC content: 40.98

Gene sequence:

>1059_bases
ATGAGTTTCATTGACGAAGCCAAGGTTTTTGTTAAGGGCGGCAATGGCGGAAATGGCTGCGTGAGTTTCCGTAGGGAAAA
GTATATTGAGTTTGGCGGCCCAGATGGTGGCAATGGTGGAGATGGCGGTTCTGTTATCTTAGAGGCTAGTAGCGCTGTTA
ATACTTTGCTATTCTTCCGCTATCATCAGCATTTGCGTGCTGAAAACGGTAAAAGTGGCTCTGGAAAAAAGAAATCTGGA
GCTTCAGGTCGCGACCTTGTTATAAAAGTCCCTATTGGAACTCAGGTATTTGATAGCCCTGGTGGGAGTTTAATTGCTGA
TCTTTCTACTGTAGGACAAAGGTATGTTGTTGCCTCTGGCGGTAAGGGAGGCGTGGGAAATGCGCAGTATAAGAGTTCTA
CTAACAGGGCTCCTGTGTACTATACTTTAGGTGCTGTAGAAGAAGAGTTTCCTATTTTCATGCAGCTGAAAGTGCTCTCT
GATATAGGGATAATAGGAATGCCCAATGCAGGGAAATCGAGTTTGCTGTCTAGATGCACTATGTCTAAAACGAAAGTCGC
TGATTATCCCTTTACTACCTTGGAGCCGCATCTAGGTGTCGCTAGAATCAACGAGTATGATCTTATTCTCGCTGATATTC
CTGGATTGATAGAAAATGCTAATGAGGGTGCCGGTTTAGGGCATAAGTTTTTAAAACACATAGAGAGGTGTTCTTTGCTC
TTACATCTCATAGATGGCTCTACCGAAGATATAGTCGGTGCGTATAAATTGGTATCACGCGAATTGGCTATGTATAGTAA
AGAGCTATCTGAAAAGCGTGAGGTGATAGTACTTAATAAATGCGACATGATCACTGAGGAAGAAATAGTCCAGAAAAAGC
ATTTATTAGAGGATTATAGCAATAAAACAGTTGTTACTCTTTCCTTGGATGATCCTTTAAACCCTTTGCTAGTAATGTTA
TATGAGATGTTACAGAAAGATGATATAGAAGAAGAATCAAAGAAATTCGATCCTTTTTTACACGTTGGCTACAACAAGAA
AAAGACACCTAAGATATAA

Upstream 100 bases:

>100_bases
TCTGAACGCATGGCTAAGTACAATGAATTGTTAAGGATTGAAGAAGATCTCTGTGGTACTGCCATACTTCGTTCCGTTAA
GATAGGGCGACATTAGCTTT

Downstream 100 bases:

>100_bases
CTTTGGCACGATCTTATACCATTAACTCCTCTTGTATGGAAAACCAAGAATGCGCTTCACAAGGCGCTCGCTAAGGGCGC
AGTTAAGGGAACTCAGAATA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSFIDEAKVFVKGGNGGNGCVSFRREKYIEFGGPDGGNGGDGGSVILEASSAVNTLLFFRYHQHLRAENGKSGSGKKKSG
ASGRDLVIKVPIGTQVFDSPGGSLIADLSTVGQRYVVASGGKGGVGNAQYKSSTNRAPVYYTLGAVEEEFPIFMQLKVLS
DIGIIGMPNAGKSSLLSRCTMSKTKVADYPFTTLEPHLGVARINEYDLILADIPGLIENANEGAGLGHKFLKHIERCSLL
LHLIDGSTEDIVGAYKLVSRELAMYSKELSEKREVIVLNKCDMITEEEIVQKKHLLEDYSNKTVVTLSLDDPLNPLLVML
YEMLQKDDIEEESKKFDPFLHVGYNKKKTPKI

Sequences:

>Translated_352_residues
MSFIDEAKVFVKGGNGGNGCVSFRREKYIEFGGPDGGNGGDGGSVILEASSAVNTLLFFRYHQHLRAENGKSGSGKKKSG
ASGRDLVIKVPIGTQVFDSPGGSLIADLSTVGQRYVVASGGKGGVGNAQYKSSTNRAPVYYTLGAVEEEFPIFMQLKVLS
DIGIIGMPNAGKSSLLSRCTMSKTKVADYPFTTLEPHLGVARINEYDLILADIPGLIENANEGAGLGHKFLKHIERCSLL
LHLIDGSTEDIVGAYKLVSRELAMYSKELSEKREVIVLNKCDMITEEEIVQKKHLLEDYSNKTVVTLSLDDPLNPLLVML
YEMLQKDDIEEESKKFDPFLHVGYNKKKTPKI
>Mature_351_residues
SFIDEAKVFVKGGNGGNGCVSFRREKYIEFGGPDGGNGGDGGSVILEASSAVNTLLFFRYHQHLRAENGKSGSGKKKSGA
SGRDLVIKVPIGTQVFDSPGGSLIADLSTVGQRYVVASGGKGGVGNAQYKSSTNRAPVYYTLGAVEEEFPIFMQLKVLSD
IGIIGMPNAGKSSLLSRCTMSKTKVADYPFTTLEPHLGVARINEYDLILADIPGLIENANEGAGLGHKFLKHIERCSLLL
HLIDGSTEDIVGAYKLVSRELAMYSKELSEKREVIVLNKCDMITEEEIVQKKHLLEDYSNKTVVTLSLDDPLNPLLVMLY
EMLQKDDIEEESKKFDPFLHVGYNKKKTPKI

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=309, Percent_Identity=41.747572815534, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI111955139, Length=292, Percent_Identity=34.5890410958904, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI111955063, Length=190, Percent_Identity=35.2631578947368, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI58761500, Length=149, Percent_Identity=28.8590604026846, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789574, Length=296, Percent_Identity=49.6621621621622, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787454, Length=99, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=328, Percent_Identity=41.4634146341463, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17552324, Length=359, Percent_Identity=28.4122562674095, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=148, Percent_Identity=31.0810810810811, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=183, Percent_Identity=28.9617486338798, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=177, Percent_Identity=32.2033898305085, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319281, Length=87, Percent_Identity=35.632183908046, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129375, Length=282, Percent_Identity=40.4255319148936, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24585318, Length=316, Percent_Identity=33.8607594936709, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24640873, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640877, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640875, Length=153, Percent_Identity=32.0261437908497, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_ANAPZ (Q2GK25)

Other databases:

- EMBL:   CP000235
- RefSeq:   YP_505276.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q2GK25
- SMR:   Q2GK25
- STRING:   Q2GK25
- GeneID:   3930072
- GenomeReviews:   CP000235_GR
- KEGG:   aph:APH_0694
- NMPDR:   fig|212042.5.peg.676
- TIGR:   APH_0694
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- PhylomeDB:   Q2GK25
- ProtClustDB:   PRK12299
- BioCyc:   APHA212042:APH_0694-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 38358; Mature: 38227

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIDEAKVFVKGGNGGNGCVSFRREKYIEFGGPDGGNGGDGGSVILEASSAVNTLLFFR
CCCCCCCEEEEECCCCCCCCCHHHHHCEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHH
YHQHLRAENGKSGSGKKKSGASGRDLVIKVPIGTQVFDSPGGSLIADLSTVGQRYVVASG
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHCCCEEEEEEC
GKGGVGNAQYKSSTNRAPVYYTLGAVEEEFPIFMQLKVLSDIGIIGMPNAGKSSLLSRCT
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHCCCEEECCCCCHHHHHHHHH
MSKTKVADYPFTTLEPHLGVARINEYDLILADIPGLIENANEGAGLGHKFLKHIERCSLL
CCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHLIDGSTEDIVGAYKLVSRELAMYSKELSEKREVIVLNKCDMITEEEIVQKKHLLEDYS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
NKTVVTLSLDDPLNPLLVMLYEMLQKDDIEEESKKFDPFLHVGYNKKKTPKI
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SFIDEAKVFVKGGNGGNGCVSFRREKYIEFGGPDGGNGGDGGSVILEASSAVNTLLFFR
CCCCCCEEEEECCCCCCCCCHHHHHCEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHH
YHQHLRAENGKSGSGKKKSGASGRDLVIKVPIGTQVFDSPGGSLIADLSTVGQRYVVASG
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHCCCEEEEEEC
GKGGVGNAQYKSSTNRAPVYYTLGAVEEEFPIFMQLKVLSDIGIIGMPNAGKSSLLSRCT
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHCCCEEECCCCCHHHHHHHHH
MSKTKVADYPFTTLEPHLGVARINEYDLILADIPGLIENANEGAGLGHKFLKHIERCSLL
CCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHLIDGSTEDIVGAYKLVSRELAMYSKELSEKREVIVLNKCDMITEEEIVQKKHLLEDYS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCC
NKTVVTLSLDDPLNPLLVMLYEMLQKDDIEEESKKFDPFLHVGYNKKKTPKI
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA