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The map label for this gene is ycfH [H]

Identifier: 88606752

GI number: 88606752

Start: 547281

End: 548093

Strand: Reverse

Name: ycfH [H]

Synonym: APH_0528

Alternate gene names: 88606752

Gene position: 548093-547281 (Counterclockwise)

Preceding gene: 88607819

Following gene: 88607476

Centisome position: 37.25

GC content: 41.08

Gene sequence:

>813_bases
GTGATAGTAGATTCGCACTGTCATTTAAATTATTTTGATTCTGCAAGCCTGCGGGATATTATCGATCACGCATGTGCCGT
GGGAGTGTCTCTTATGCAGACTGTATGCACTACTATAGAAGAGTTTCCTGTACTACTAGAGATAGCCAATGGCTATGCAC
AAGTATATGCCTCTGTAGGTGTCCATCCTTGTAATAGTGCCAAGGGCGAATTTAGTTCAGTAGATGATTTGGTTGCCTTT
GCGCAAAATAATAAAGTCATCGGTCTGGGGGAAACCGGTTTAGATTTTTATCGGAGTGAAGAGGGCATCGATAAACAAGA
GAAAAGCTTTCTTGCTCATATAGATGCAGCTAGAGTAACGCAGTTACCTGTCATTATTCACTCAAGAAATGCTGATACTA
GAATGGCTGAAATCTGTGCCTCTGAAATGAAAAATGGTGCATTCAAAGGAGTTATGCATTGTTTTGCTTCCTCGATGGAA
TTGGCAAGGCACTCGCTCGATGCTGGACTCTATATCTCATTTTCTGGCATTCTTACCTTCAAAAATGCAGGGTTTTTGAG
AGATATAGCTAAATTTGTCCCCAGAGACCGTGTAGTTGTCGAAACCGATTCACCATATTTATGTCCAGAGCCCCACAGAG
GGAAACAAAACTCTCCAGAGATGACCAGATTTGTCGTAGAAAGTTTGGCTCAGATATGGGAAGAAAGCGTTGACGTAGTT
AGCGAAGTAACTACGAAGAATTTTTTCACACTTTTTGATAAATGTGCTCGTCTATACTATGCATCAGAAGAATCCAATAA
TTTGCGCTCTTGA

Upstream 100 bases:

>100_bases
CTGCTGTCTTAATCTAGCAATTTATTAAATGTCTACGTTGTGCTTCTCGGCAAACCTGATAGAATCCAGAGGTTGCTTTG
GTTTTCACTGAGTATTGTTG

Downstream 100 bases:

>100_bases
TACAGCAGATCTAGAACGTGCAACTACCTTAGCAAAGGCAATATCTGGTAAGGTTGCTATGGCAAAGGTAGGGCTAGAAT
TTTTTACAGCTCACGGACTT

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MIVDSHCHLNYFDSASLRDIIDHACAVGVSLMQTVCTTIEEFPVLLEIANGYAQVYASVGVHPCNSAKGEFSSVDDLVAF
AQNNKVIGLGETGLDFYRSEEGIDKQEKSFLAHIDAARVTQLPVIIHSRNADTRMAEICASEMKNGAFKGVMHCFASSME
LARHSLDAGLYISFSGILTFKNAGFLRDIAKFVPRDRVVVETDSPYLCPEPHRGKQNSPEMTRFVVESLAQIWEESVDVV
SEVTTKNFFTLFDKCARLYYASEESNNLRS

Sequences:

>Translated_270_residues
MIVDSHCHLNYFDSASLRDIIDHACAVGVSLMQTVCTTIEEFPVLLEIANGYAQVYASVGVHPCNSAKGEFSSVDDLVAF
AQNNKVIGLGETGLDFYRSEEGIDKQEKSFLAHIDAARVTQLPVIIHSRNADTRMAEICASEMKNGAFKGVMHCFASSME
LARHSLDAGLYISFSGILTFKNAGFLRDIAKFVPRDRVVVETDSPYLCPEPHRGKQNSPEMTRFVVESLAQIWEESVDVV
SEVTTKNFFTLFDKCARLYYASEESNNLRS
>Mature_270_residues
MIVDSHCHLNYFDSASLRDIIDHACAVGVSLMQTVCTTIEEFPVLLEIANGYAQVYASVGVHPCNSAKGEFSSVDDLVAF
AQNNKVIGLGETGLDFYRSEEGIDKQEKSFLAHIDAARVTQLPVIIHSRNADTRMAEICASEMKNGAFKGVMHCFASSME
LARHSLDAGLYISFSGILTFKNAGFLRDIAKFVPRDRVVVETDSPYLCPEPHRGKQNSPEMTRFVVESLAQIWEESVDVV
SEVTTKNFFTLFDKCARLYYASEESNNLRS

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=271, Percent_Identity=28.4132841328413, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI110349734, Length=271, Percent_Identity=28.0442804428044, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI14042943, Length=197, Percent_Identity=28.9340101522843, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI226061853, Length=277, Percent_Identity=27.7978339350181, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226061614, Length=263, Percent_Identity=28.1368821292776, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI225903439, Length=168, Percent_Identity=30.3571428571429, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI225903424, Length=161, Percent_Identity=29.1925465838509, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=26.2008733624454, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=43.5294117647059, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=27.1653543307087, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI48994985, Length=241, Percent_Identity=26.5560165975104, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=29.6577946768061, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=204, Percent_Identity=30.3921568627451, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=216, Percent_Identity=28.7037037037037, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=172, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24648690, Length=269, Percent_Identity=25.6505576208178, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586117, Length=230, Percent_Identity=26.5217391304348, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330018, Length=230, Percent_Identity=26.5217391304348, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29984; Mature: 29984

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDSHCHLNYFDSASLRDIIDHACAVGVSLMQTVCTTIEEFPVLLEIANGYAQVYASVG
CEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VHPCNSAKGEFSSVDDLVAFAQNNKVIGLGETGLDFYRSEEGIDKQEKSFLAHIDAARVT
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
QLPVIIHSRNADTRMAEICASEMKNGAFKGVMHCFASSMELARHSLDAGLYISFSGILTF
HCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEE
KNAGFLRDIAKFVPRDRVVVETDSPYLCPEPHRGKQNSPEMTRFVVESLAQIWEESVDVV
CCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SEVTTKNFFTLFDKCARLYYASEESNNLRS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIVDSHCHLNYFDSASLRDIIDHACAVGVSLMQTVCTTIEEFPVLLEIANGYAQVYASVG
CEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VHPCNSAKGEFSSVDDLVAFAQNNKVIGLGETGLDFYRSEEGIDKQEKSFLAHIDAARVT
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHH
QLPVIIHSRNADTRMAEICASEMKNGAFKGVMHCFASSMELARHSLDAGLYISFSGILTF
HCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEE
KNAGFLRDIAKFVPRDRVVVETDSPYLCPEPHRGKQNSPEMTRFVVESLAQIWEESVDVV
CCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SEVTTKNFFTLFDKCARLYYASEESNNLRS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]