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The map label for this gene is glpK [H]

Identifier: 87200454

GI number: 87200454

Start: 2626298

End: 2627761

Strand: Reverse

Name: glpK [H]

Synonym: Saro_2441

Alternate gene names: 87200454

Gene position: 2627761-2626298 (Counterclockwise)

Preceding gene: 87200455

Following gene: 87200452

Centisome position: 73.78

GC content: 68.24

Gene sequence:

>1464_bases
ATGACTGACGAGCGCCGCATCCTTGTTCTCGACGAAGGAACGACCTCGACCCGTGCGATCCTCTATTCCGCGCGAGGCGA
GGTGCTGGGCTGTGCGCAGGAAGAACTGACGCAATACTATCCCGCGCCCGGCCTTGTCGAACACGATGCGGCCGAGATCT
GGGAGCGGACCCTGCGCTGCGCGCGCGCCATGGTGGCGCAGGCGGGCGGGGCCGGGCGAATTGCCGGTATCGGCGTCACC
AACCAGCGTGAAACTGTCGTCGCCTGGGATCGTTCGACCGGCAAGCCGCTGACCCGTGCCATCGTGTGGCAGGACCGCCG
AACTGAAGAGCGTTGCCGCGAGCTGCGCGATGCAGGTCATGAGGCGGCGATCCAGCAGGCAACCGGCCTGCTGCTCGATC
CCTACTTTTCAGCCAGCAAGATGGAGTGGATTCTCCGAAACGTCCCCGAAGCGCGCGCGCTGGGTTCGCGGCTGGCGTTC
GGGACGGTGGAAAGCTGGCTGGTCTGGAACCTGACCGGTGGCCTGCATGTCAGCGACGTGACCAATGCCAGCCGCACCTC
GCTGTTTCCGCTCGAAGGCGCGAGCTGGGACGAAGGACTGTGCGATCTGTTCGGCGTGCCCCTTTCGGCCTTGCCCGAAG
TGGTGCCGAGCGCAGGCGCATTCGGCACGACGCGGGCAGACCTGCTGGGCGGAGCGATTCCCGTCACCGGGCTTGCCGGC
GATCAGCAGGCCGCGACAATCGGGCAGGGCTGTTTCCGTGCGGGCGAGGCCAAGGCGACGCTCGGCACCGGGGCCTTCAT
CCTTGCCAACATGGGCACCCGACCGCCGCGTTCGGCGCATCGCCTGCTTGGCACGGTACTGTGCGAGGTGGACGGCGTGC
GCACTTTCGCGCTGGAAGGTTCGGTCTTTGCCGCGGGCAGCGTGGTCAAGTGGCTGCGCGACAGCATTGGCCTGCTGGGC
ACGTCAGCGGAGAGCGAGGCGCTGGCAAGGTCCGTGCCGGACAGCGGCGGCGTGGTCGTCGTTCCGGCGTTGTCGGGGCT
GGGCGCGCCCTACTGGAAACCCGATGCGCGCGCGAGCATCCACGGCCTGTCCTTTGCGACGACGCGGGCGCATCTCGTGC
GTGCGGCGCTCGAGGCGATGGCGCACGTGTTCCATGACCTCGGTCATGCCTTTGCCGCAGATGGGGCAGGGTGGCAGGTG
CTGCGCCTGGACGGCGGTATGAGCGCCAACGACTGGCTGGCACAGGACATCGCCGACGTGCTCGGCATCCGCTGCGAGCG
GCCGGTCGACGTGGAGACGACCGCACGCGGGGCCGCGATCCTGGCGGCGATCGGTGCTGGGCTATGCCCTTCGCTCGACC
ATGCGCGAACCATCGTCGCACCTTCCGCCGCGTTCGAGCCAGGGATGGCGGCGCAAGAACGTCACGGGCGTTTGGTCCGG
TGGCGCGAGGCTATCGGGGGATAG

Upstream 100 bases:

>100_bases
GAGGCCGGGGACGTGCTTTGGCGGCGGACCAAGCTGGGCCTGCGGCTGGACGCGGCGGAGCAGGCCGACCTGGCGCAATT
CATGAAAGCGAACCTGCCCA

Downstream 100 bases:

>100_bases
CCCCCGGCCCGATCAGCGGAACGCGAGGACTTCGGCAGAAGAGAGTCGCGCCATGGCGAGCCCGGCGGCGCGGCGGCTGT
CGATCCAGCGGCCATTGCCC

Product: carbohydrate kinase

Products: NA

Alternate protein names: ATP:glycerol 3-phosphotransferase; Glycerokinase; GK [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTDERRILVLDEGTTSTRAILYSARGEVLGCAQEELTQYYPAPGLVEHDAAEIWERTLRCARAMVAQAGGAGRIAGIGVT
NQRETVVAWDRSTGKPLTRAIVWQDRRTEERCRELRDAGHEAAIQQATGLLLDPYFSASKMEWILRNVPEARALGSRLAF
GTVESWLVWNLTGGLHVSDVTNASRTSLFPLEGASWDEGLCDLFGVPLSALPEVVPSAGAFGTTRADLLGGAIPVTGLAG
DQQAATIGQGCFRAGEAKATLGTGAFILANMGTRPPRSAHRLLGTVLCEVDGVRTFALEGSVFAAGSVVKWLRDSIGLLG
TSAESEALARSVPDSGGVVVVPALSGLGAPYWKPDARASIHGLSFATTRAHLVRAALEAMAHVFHDLGHAFAADGAGWQV
LRLDGGMSANDWLAQDIADVLGIRCERPVDVETTARGAAILAAIGAGLCPSLDHARTIVAPSAAFEPGMAAQERHGRLVR
WREAIGG

Sequences:

>Translated_487_residues
MTDERRILVLDEGTTSTRAILYSARGEVLGCAQEELTQYYPAPGLVEHDAAEIWERTLRCARAMVAQAGGAGRIAGIGVT
NQRETVVAWDRSTGKPLTRAIVWQDRRTEERCRELRDAGHEAAIQQATGLLLDPYFSASKMEWILRNVPEARALGSRLAF
GTVESWLVWNLTGGLHVSDVTNASRTSLFPLEGASWDEGLCDLFGVPLSALPEVVPSAGAFGTTRADLLGGAIPVTGLAG
DQQAATIGQGCFRAGEAKATLGTGAFILANMGTRPPRSAHRLLGTVLCEVDGVRTFALEGSVFAAGSVVKWLRDSIGLLG
TSAESEALARSVPDSGGVVVVPALSGLGAPYWKPDARASIHGLSFATTRAHLVRAALEAMAHVFHDLGHAFAADGAGWQV
LRLDGGMSANDWLAQDIADVLGIRCERPVDVETTARGAAILAAIGAGLCPSLDHARTIVAPSAAFEPGMAAQERHGRLVR
WREAIGG
>Mature_486_residues
TDERRILVLDEGTTSTRAILYSARGEVLGCAQEELTQYYPAPGLVEHDAAEIWERTLRCARAMVAQAGGAGRIAGIGVTN
QRETVVAWDRSTGKPLTRAIVWQDRRTEERCRELRDAGHEAAIQQATGLLLDPYFSASKMEWILRNVPEARALGSRLAFG
TVESWLVWNLTGGLHVSDVTNASRTSLFPLEGASWDEGLCDLFGVPLSALPEVVPSAGAFGTTRADLLGGAIPVTGLAGD
QQAATIGQGCFRAGEAKATLGTGAFILANMGTRPPRSAHRLLGTVLCEVDGVRTFALEGSVFAAGSVVKWLRDSIGLLGT
SAESEALARSVPDSGGVVVVPALSGLGAPYWKPDARASIHGLSFATTRAHLVRAALEAMAHVFHDLGHAFAADGAGWQVL
RLDGGMSANDWLAQDIADVLGIRCERPVDVETTARGAAILAAIGAGLCPSLDHARTIVAPSAAFEPGMAAQERHGRLVRW
REAIGG

Specific function: Key enzyme in the regulation of glycerol uptake and metabolism [H]

COG id: COG0554

COG function: function code C; Glycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI189409120, Length=493, Percent_Identity=41.7849898580122, Blast_Score=345, Evalue=4e-95,
Organism=Homo sapiens, GI4504007, Length=493, Percent_Identity=41.7849898580122, Blast_Score=345, Evalue=5e-95,
Organism=Homo sapiens, GI42794763, Length=499, Percent_Identity=41.2825651302605, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI41393575, Length=492, Percent_Identity=41.260162601626, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI88196792, Length=500, Percent_Identity=29.4, Blast_Score=238, Evalue=1e-62,
Organism=Escherichia coli, GI1790361, Length=491, Percent_Identity=43.9918533604888, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1790005, Length=484, Percent_Identity=27.8925619834711, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789987, Length=458, Percent_Identity=27.9475982532751, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787789, Length=480, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789168, Length=477, Percent_Identity=24.9475890985325, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=491, Percent_Identity=39.1038696537678, Blast_Score=312, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI71986140, Length=518, Percent_Identity=26.0617760617761, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71986147, Length=296, Percent_Identity=30.0675675675676, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6321755, Length=485, Percent_Identity=36.701030927835, Blast_Score=257, Evalue=3e-69,
Organism=Drosophila melanogaster, GI17864214, Length=496, Percent_Identity=39.5161290322581, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24654573, Length=440, Percent_Identity=40.6818181818182, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24655555, Length=501, Percent_Identity=36.3273453093812, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24655560, Length=501, Percent_Identity=36.3273453093812, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24655570, Length=501, Percent_Identity=36.3273453093812, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24655574, Length=501, Percent_Identity=36.3273453093812, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24655565, Length=501, Percent_Identity=36.3273453093812, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI19922058, Length=521, Percent_Identity=31.6698656429942, Blast_Score=244, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24652871, Length=487, Percent_Identity=31.8275154004107, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24656367, Length=511, Percent_Identity=27.3972602739726, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21357867, Length=528, Percent_Identity=27.0833333333333, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24656372, Length=372, Percent_Identity=29.5698924731183, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45552909, Length=265, Percent_Identity=30.9433962264151, Blast_Score=103, Evalue=4e-22,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR005999 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.30 [H]

Molecular weight: Translated: 51424; Mature: 51293

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDERRILVLDEGTTSTRAILYSARGEVLGCAQEELTQYYPAPGLVEHDAAEIWERTLRC
CCCCCEEEEEECCCCCCEEEEEECCCCEEECHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ARAMVAQAGGAGRIAGIGVTNQRETVVAWDRSTGKPLTRAIVWQDRRTEERCRELRDAGH
HHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHCCH
EAAIQQATGLLLDPYFSASKMEWILRNVPEARALGSRLAFGTVESWLVWNLTGGLHVSDV
HHHHHHHCCCEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEECC
TNASRTSLFPLEGASWDEGLCDLFGVPLSALPEVVPSAGAFGTTRADLLGGAIPVTGLAG
CCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCC
DQQAATIGQGCFRAGEAKATLGTGAFILANMGTRPPRSAHRLLGTVLCEVDGVRTFALEG
CCHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECC
SVFAAGSVVKWLRDSIGLLGTSAESEALARSVPDSGGVVVVPALSGLGAPYWKPDARASI
CEEHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEE
HGLSFATTRAHLVRAALEAMAHVFHDLGHAFAADGAGWQVLRLDGGMSANDWLAQDIADV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
LGIRCERPVDVETTARGAAILAAIGAGLCPSLDHARTIVAPSAAFEPGMAAQERHGRLVR
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCHHH
WREAIGG
HHHHHCC
>Mature Secondary Structure 
TDERRILVLDEGTTSTRAILYSARGEVLGCAQEELTQYYPAPGLVEHDAAEIWERTLRC
CCCCEEEEEECCCCCCEEEEEECCCCEEECHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ARAMVAQAGGAGRIAGIGVTNQRETVVAWDRSTGKPLTRAIVWQDRRTEERCRELRDAGH
HHHHHHHCCCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHCCH
EAAIQQATGLLLDPYFSASKMEWILRNVPEARALGSRLAFGTVESWLVWNLTGGLHVSDV
HHHHHHHCCCEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEECC
TNASRTSLFPLEGASWDEGLCDLFGVPLSALPEVVPSAGAFGTTRADLLGGAIPVTGLAG
CCCCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCC
DQQAATIGQGCFRAGEAKATLGTGAFILANMGTRPPRSAHRLLGTVLCEVDGVRTFALEG
CCHHHHHHHHHHHCCCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECC
SVFAAGSVVKWLRDSIGLLGTSAESEALARSVPDSGGVVVVPALSGLGAPYWKPDARASI
CEEHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEE
HGLSFATTRAHLVRAALEAMAHVFHDLGHAFAADGAGWQVLRLDGGMSANDWLAQDIADV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
LGIRCERPVDVETTARGAAILAAIGAGLCPSLDHARTIVAPSAAFEPGMAAQERHGRLVR
HCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCHHH
WREAIGG
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA