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The map label for this gene is kdgR [H]

Identifier: 87200447

GI number: 87200447

Start: 2617282

End: 2618100

Strand: Reverse

Name: kdgR [H]

Synonym: Saro_2434

Alternate gene names: 87200447

Gene position: 2618100-2617282 (Counterclockwise)

Preceding gene: 87200448

Following gene: 87200446

Centisome position: 73.51

GC content: 65.57

Gene sequence:

>819_bases
GTGAACGATTTCGACGATCTGCCAGAAAACGATGGCGACGCGGCCGGTGAAGGGCGCGGCGCGGGCAAGTATCGCGCCCC
TGCGCTGGAGAAGGGGCTCGACGTGATCGCCCTGCTGGTCGACGTAGGTCACCCGCTGACCATGACCGAAATCTGCCAGC
GGCTCGGCCGCTCGCAGGGCGAGATGTTCCGCATGGTGCAGGTCTTGCAGGCGAGGGGCTTCGTCGAACAGGACCGCGCG
ACCGACGGATATTACCTGACCGACCTGCTCTTCACCATGGCCATGCGTCAGCCGCCGACGCAGAGCCTCGTCGAGGTCGC
CCTGCCGCGAATGCGCGCGCTGGCGATGGAAATTGGTCAGTCGTGCCATCTCGTGTTCCACAGCCGGGGCGAGATCGTTG
TCGTCGCGCGCATGGAATCGAACGAACAGATCGGCTTTTCGGTGCGCATCGGCCATCGCCTGCCACTTCAGCAGTCGGTT
TCGGGCACTGTGCTGTTCGGTTTTCAGCCGGAAGACATGCGCCGCATGTGGCTGGACCTCCTGCCGAAGAACGCCGATCC
CGAAGAAGTGGCGGCGTTCGTCGAGCGTGCGGATGCGGCCCGCGAGAAGGGCTATGCCCGCGCGGCAAGCTCCTTCGTCA
GCGGGATCAGCGACATTTCCGCGCCGATCATGCGCGGCGACCGGGCCGCTGCCGCACTCACCGTGCCATTCATCCGCCAT
GCCAACCTGCGCCACACCATCGGGTCCACCACCGAGGTCCTGACCGAAACCGCGCGCCAGATCTCCGATCTTCTGCCCCA
CGCCGACAGCCGGGTCTGA

Upstream 100 bases:

>100_bases
CGGGCGGGATGAAAGTGCCGCTTATCCCCGCTTGCGCCGCGGCGAGCGGTACATGTACGCCTGAATCATTCAGCAATACG
GCGAGCGAGGACGACCCCGA

Downstream 100 bases:

>100_bases
GCGCCTTCGCCCTCATGGGGCAGCACGCCACAGATTCCGGTTGTATATATGAAATGAATTTTTGTATGTGACGAAAGGAG
GGGCGGGCAGTTCGGCCCGG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MNDFDDLPENDGDAAGEGRGAGKYRAPALEKGLDVIALLVDVGHPLTMTEICQRLGRSQGEMFRMVQVLQARGFVEQDRA
TDGYYLTDLLFTMAMRQPPTQSLVEVALPRMRALAMEIGQSCHLVFHSRGEIVVVARMESNEQIGFSVRIGHRLPLQQSV
SGTVLFGFQPEDMRRMWLDLLPKNADPEEVAAFVERADAAREKGYARAASSFVSGISDISAPIMRGDRAAAALTVPFIRH
ANLRHTIGSTTEVLTETARQISDLLPHADSRV

Sequences:

>Translated_272_residues
MNDFDDLPENDGDAAGEGRGAGKYRAPALEKGLDVIALLVDVGHPLTMTEICQRLGRSQGEMFRMVQVLQARGFVEQDRA
TDGYYLTDLLFTMAMRQPPTQSLVEVALPRMRALAMEIGQSCHLVFHSRGEIVVVARMESNEQIGFSVRIGHRLPLQQSV
SGTVLFGFQPEDMRRMWLDLLPKNADPEEVAAFVERADAAREKGYARAASSFVSGISDISAPIMRGDRAAAALTVPFIRH
ANLRHTIGSTTEVLTETARQISDLLPHADSRV
>Mature_272_residues
MNDFDDLPENDGDAAGEGRGAGKYRAPALEKGLDVIALLVDVGHPLTMTEICQRLGRSQGEMFRMVQVLQARGFVEQDRA
TDGYYLTDLLFTMAMRQPPTQSLVEVALPRMRALAMEIGQSCHLVFHSRGEIVVVARMESNEQIGFSVRIGHRLPLQQSV
SGTVLFGFQPEDMRRMWLDLLPKNADPEEVAAFVERADAAREKGYARAASSFVSGISDISAPIMRGDRAAAALTVPFIRH
ANLRHTIGSTTEVLTETARQISDLLPHADSRV

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=257, Percent_Identity=24.9027237354086, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788131, Length=248, Percent_Identity=25.4032258064516, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29949; Mature: 29949

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFDDLPENDGDAAGEGRGAGKYRAPALEKGLDVIALLVDVGHPLTMTEICQRLGRSQG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
EMFRMVQVLQARGFVEQDRATDGYYLTDLLFTMAMRQPPTQSLVEVALPRMRALAMEIGQ
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SCHLVFHSRGEIVVVARMESNEQIGFSVRIGHRLPLQQSVSGTVLFGFQPEDMRRMWLDL
CEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHH
LPKNADPEEVAAFVERADAAREKGYARAASSFVSGISDISAPIMRGDRAAAALTVPFIRH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
ANLRHTIGSTTEVLTETARQISDLLPHADSRV
CCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDFDDLPENDGDAAGEGRGAGKYRAPALEKGLDVIALLVDVGHPLTMTEICQRLGRSQG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
EMFRMVQVLQARGFVEQDRATDGYYLTDLLFTMAMRQPPTQSLVEVALPRMRALAMEIGQ
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SCHLVFHSRGEIVVVARMESNEQIGFSVRIGHRLPLQQSVSGTVLFGFQPEDMRRMWLDL
CEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHH
LPKNADPEEVAAFVERADAAREKGYARAASSFVSGISDISAPIMRGDRAAAALTVPFIRH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
ANLRHTIGSTTEVLTETARQISDLLPHADSRV
CCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]