| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is cobT [H]
Identifier: 87200402
GI number: 87200402
Start: 2554241
End: 2556055
Strand: Reverse
Name: cobT [H]
Synonym: Saro_2389
Alternate gene names: 87200402
Gene position: 2556055-2554241 (Counterclockwise)
Preceding gene: 87200403
Following gene: 87200401
Centisome position: 71.77
GC content: 66.83
Gene sequence:
>1815_bases TTGGCTGACGAATCCCCCCTCGACCGCTTCCGTTCGGTTCTGACCGGCACCGCGCGCGCCATTTCGCACGACCCCGAAGT GGAGGTCGCGTGGACGGCCGATGCGCCGGTTCAGTCGGGCAGTTCGATGCGCGTGCCCATGCCCGGCCGGGCTCTGCCCG CAGAGCAGGTGGCCGAGGCGCGAGGGCACGCGGATTCGATGGCGCTGCGGCTGCGCCATCACAATGCGGCGCTGCACGGA CGCAATGCCCCGAGCGAGGCGCTGGCCCGCGCGTGCTACGATGCGGTCGAGCAGGTGCGCTACGAAGCGTTGGGCTCGAA TGCCTATGCCGGAATGCGCGGAAACCTCGATGCGGCGGTCTCGATGCGCATGGCGTCCGATCCGATCAGCCGCGCCGCCA AGCCCGAGGACGTGCCTCTGCCGACCGCGCTGGCGCTGCTTCTGCGCGAGAAGCTGACGGGGCAGGTGGCCCCTGCCTCG ACCCAGACCGGCATGGCGATGGTCCGTAGCTGGATCGAGAGCAAGGTCGGCAACGACTTCGAGGGACTGGCGCTCTCGCT CGACGACCAGCGGGCGTTCCAGCAGCTTGCGCTGGACATGCTCCAGCATCTCGATCTTACCCAGTCCGCGTCCGATCAGG ACGAAGATACCGAGGAAGACGAGGGCGAACAGCAGGAGGACGAGGGCGAGGAAGAGCCCAGCACGTCCGACGACCAGGAG CAGCAGCCTTCGGAAGTCGCCGGCGATACCAGCGAGGGCGACGAGGACTCCGAAAGCGAGCAGGAAGTCGAGCAGAACGA CGATGCTGCCGATGCGGACATGGCCGACGAGGGCGAGGAAGGCATGCTGCCCACGCGCCCGAACCGCCCGTGGACCGACC TGCCCGAGAACTTCGACTACAAGGCCTTCACCGTCCAGTTCGACGAGGTCGTATCGGCAACCGACCTGTGCGACGAGGAA GAGCTGACGCGGCTGCGGGCCTATCTCGACATGCAGCTCAAGGGCTTGCAGGGCGTGGTTACGCGGCTGGCGAACCGGTT GCAGCGCCGCCTGATGGCCCAGCAGAACCGTTCGTGGGACTTTGACCAGGAAGAGGGGCTGCTCGATGCCGCTCGTCTGG CGCGCGTCGTGATCTCGCCCGGGCATTCGCTGTCCTACAAGGTCGAGCGTGACGTCGAGTTCAAGGACACGATCGTCACC CTGCTGATCGACAATTCGGGGTCGATGCGCGGCCGCCCGATCTCGATCGCGGCGATCAGCGCCGACATCCTGGCGCGCAC GCTGGAACGGTGCGGGGTCAAGACCGAGATTCTCGGCTTCACCACCCGCGCGTGGAAGGGCGGGCAGAGCCGCGAGGCGT GGCTGGCCGGTGGAAAGCCTGCGCAGCCCGGGCGCCTCAACGACCTGCGCCACATCGTCTACAAGAAGGCGGACGAGCCG TGGCGCCGCGCGCGCAAGAACCTCGGGCTGATGATGCGCGAGGGGCTGCTCAAGGAAAACATCGACGGCGAGGCGCTGCT CTGGGCGCACACCCGCCTGCTCGCCCGGCCCGAGGATCGCCGCATCCTGATGGTCATTTCCGATGGCGCGCCGGTCGACG ACTCCACCCTGTCGGTGAACAACGCGGGTTACCTCGAGCAGCACTTGCGCAAGGTCATCGACTGGATCGAGAAGCAATCG CCGGTCCAGCTCGTCGCCATCGGCATCGGTCACGACGTAACGCGGTACTATCGCCGCGCGGTGACGATCATGGACGCAGA ACAGCTTGGCGGCACGATCATCGAGCAGCTTGCGGACCTGTTCGAGGACGAATAG
Upstream 100 bases:
>100_bases CAAAGACCGGCCAGAAGATCGTCTGATGTAGTGCATGGCCGAGGGAGGCCTCCGCTTTCGCGGGGGCCCGGCTCTCCGGC CCGAATCCTGAAGGCTGGCA
Downstream 100 bases:
>100_bases GCGCGGCTTGACGGCCCGTTCTTAACCGGGCAGTTAAACCGGCATGAGCCAGATGTCCGTCAGCGAAGCCGTTGTTTCCC GCCGCTCGATCCGCCGCTTC
Product: cobalt chelatase, pCobT subunit
Products: NA
Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]
Number of amino acids: Translated: 604; Mature: 603
Protein sequence:
>604_residues MADESPLDRFRSVLTGTARAISHDPEVEVAWTADAPVQSGSSMRVPMPGRALPAEQVAEARGHADSMALRLRHHNAALHG RNAPSEALARACYDAVEQVRYEALGSNAYAGMRGNLDAAVSMRMASDPISRAAKPEDVPLPTALALLLREKLTGQVAPAS TQTGMAMVRSWIESKVGNDFEGLALSLDDQRAFQQLALDMLQHLDLTQSASDQDEDTEEDEGEQQEDEGEEEPSTSDDQE QQPSEVAGDTSEGDEDSESEQEVEQNDDAADADMADEGEEGMLPTRPNRPWTDLPENFDYKAFTVQFDEVVSATDLCDEE ELTRLRAYLDMQLKGLQGVVTRLANRLQRRLMAQQNRSWDFDQEEGLLDAARLARVVISPGHSLSYKVERDVEFKDTIVT LLIDNSGSMRGRPISIAAISADILARTLERCGVKTEILGFTTRAWKGGQSREAWLAGGKPAQPGRLNDLRHIVYKKADEP WRRARKNLGLMMREGLLKENIDGEALLWAHTRLLARPEDRRILMVISDGAPVDDSTLSVNNAGYLEQHLRKVIDWIEKQS PVQLVAIGIGHDVTRYYRRAVTIMDAEQLGGTIIEQLADLFEDE
Sequences:
>Translated_604_residues MADESPLDRFRSVLTGTARAISHDPEVEVAWTADAPVQSGSSMRVPMPGRALPAEQVAEARGHADSMALRLRHHNAALHG RNAPSEALARACYDAVEQVRYEALGSNAYAGMRGNLDAAVSMRMASDPISRAAKPEDVPLPTALALLLREKLTGQVAPAS TQTGMAMVRSWIESKVGNDFEGLALSLDDQRAFQQLALDMLQHLDLTQSASDQDEDTEEDEGEQQEDEGEEEPSTSDDQE QQPSEVAGDTSEGDEDSESEQEVEQNDDAADADMADEGEEGMLPTRPNRPWTDLPENFDYKAFTVQFDEVVSATDLCDEE ELTRLRAYLDMQLKGLQGVVTRLANRLQRRLMAQQNRSWDFDQEEGLLDAARLARVVISPGHSLSYKVERDVEFKDTIVT LLIDNSGSMRGRPISIAAISADILARTLERCGVKTEILGFTTRAWKGGQSREAWLAGGKPAQPGRLNDLRHIVYKKADEP WRRARKNLGLMMREGLLKENIDGEALLWAHTRLLARPEDRRILMVISDGAPVDDSTLSVNNAGYLEQHLRKVIDWIEKQS PVQLVAIGIGHDVTRYYRRAVTIMDAEQLGGTIIEQLADLFEDE >Mature_603_residues ADESPLDRFRSVLTGTARAISHDPEVEVAWTADAPVQSGSSMRVPMPGRALPAEQVAEARGHADSMALRLRHHNAALHGR NAPSEALARACYDAVEQVRYEALGSNAYAGMRGNLDAAVSMRMASDPISRAAKPEDVPLPTALALLLREKLTGQVAPAST QTGMAMVRSWIESKVGNDFEGLALSLDDQRAFQQLALDMLQHLDLTQSASDQDEDTEEDEGEQQEDEGEEEPSTSDDQEQ QPSEVAGDTSEGDEDSESEQEVEQNDDAADADMADEGEEGMLPTRPNRPWTDLPENFDYKAFTVQFDEVVSATDLCDEEE LTRLRAYLDMQLKGLQGVVTRLANRLQRRLMAQQNRSWDFDQEEGLLDAARLARVVISPGHSLSYKVERDVEFKDTIVTL LIDNSGSMRGRPISIAAISADILARTLERCGVKTEILGFTTRAWKGGQSREAWLAGGKPAQPGRLNDLRHIVYKKADEPW RRARKNLGLMMREGLLKENIDGEALLWAHTRLLARPEDRRILMVISDGAPVDDSTLSVNNAGYLEQHLRKVIDWIEKQSP VQLVAIGIGHDVTRYYRRAVTIMDAEQLGGTIIEQLADLFEDE
Specific function: Catalyzes cobalt insertion in the corrin ring [H]
COG id: COG4547
COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 VWFA domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006538 - InterPro: IPR002035 [H]
Pfam domain/function: PF06213 CobT [H]
EC number: =6.6.1.2 [H]
Molecular weight: Translated: 66939; Mature: 66808
Theoretical pI: Translated: 4.36; Mature: 4.36
Prosite motif: PS50234 VWFA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADESPLDRFRSVLTGTARAISHDPEVEVAWTADAPVQSGSSMRVPMPGRALPAEQVAEA CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHH RGHADSMALRLRHHNAALHGRNAPSEALARACYDAVEQVRYEALGSNAYAGMRGNLDAAV CCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH SMRMASDPISRAAKPEDVPLPTALALLLREKLTGQVAPASTQTGMAMVRSWIESKVGNDF HHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCC EGLALSLDDQRAFQQLALDMLQHLDLTQSASDQDEDTEEDEGEQQEDEGEEEPSTSDDQE CCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHH QQPSEVAGDTSEGDEDSESEQEVEQNDDAADADMADEGEEGMLPTRPNRPWTDLPENFDY CCCHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC KAFTVQFDEVVSATDLCDEEELTRLRAYLDMQLKGLQGVVTRLANRLQRRLMAQQNRSWD EEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC FDQEEGLLDAARLARVVISPGHSLSYKVERDVEFKDTIVTLLIDNSGSMRGRPISIAAIS CCHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEHHH ADILARTLERCGVKTEILGFTTRAWKGGQSREAWLAGGKPAQPGRLNDLRHIVYKKADEP HHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCH WRRARKNLGLMMREGLLKENIDGEALLWAHTRLLARPEDRRILMVISDGAPVDDSTLSVN HHHHHHHCCHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECC NAGYLEQHLRKVIDWIEKQSPVQLVAIGIGHDVTRYYRRAVTIMDAEQLGGTIIEQLADL CCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHEECHHHHCHHHHHHHHHH FEDE HCCC >Mature Secondary Structure ADESPLDRFRSVLTGTARAISHDPEVEVAWTADAPVQSGSSMRVPMPGRALPAEQVAEA CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCHHHHHHH RGHADSMALRLRHHNAALHGRNAPSEALARACYDAVEQVRYEALGSNAYAGMRGNLDAAV CCCHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH SMRMASDPISRAAKPEDVPLPTALALLLREKLTGQVAPASTQTGMAMVRSWIESKVGNDF HHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCC EGLALSLDDQRAFQQLALDMLQHLDLTQSASDQDEDTEEDEGEQQEDEGEEEPSTSDDQE CCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCHH QQPSEVAGDTSEGDEDSESEQEVEQNDDAADADMADEGEEGMLPTRPNRPWTDLPENFDY CCCHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC KAFTVQFDEVVSATDLCDEEELTRLRAYLDMQLKGLQGVVTRLANRLQRRLMAQQNRSWD EEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC FDQEEGLLDAARLARVVISPGHSLSYKVERDVEFKDTIVTLLIDNSGSMRGRPISIAAIS CCHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEHHH ADILARTLERCGVKTEILGFTTRAWKGGQSREAWLAGGKPAQPGRLNDLRHIVYKKADEP HHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCH WRRARKNLGLMMREGLLKENIDGEALLWAHTRLLARPEDRRILMVISDGAPVDDSTLSVN HHHHHHHCCHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEECC NAGYLEQHLRKVIDWIEKQSPVQLVAIGIGHDVTRYYRRAVTIMDAEQLGGTIIEQLADL CCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHEECHHHHCHHHHHHHHHH FEDE HCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1917840 [H]