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The map label for this gene is trxB [H]

Identifier: 87200357

GI number: 87200357

Start: 2489959

End: 2490927

Strand: Reverse

Name: trxB [H]

Synonym: Saro_2343

Alternate gene names: 87200357

Gene position: 2490927-2489959 (Counterclockwise)

Preceding gene: 87200358

Following gene: 87200352

Centisome position: 69.94

GC content: 66.15

Gene sequence:

>969_bases
ATGGCGACGACGCACAAGACCCGCATGCTCATCATCGGTTCCGGCCCGGCCGGACTTTCCGCCGCGATCTATGGCGCGCG
CGCGGGGATGGAGCCGATCGTGGTGCAGGGTCTTCAGCCTGGCGGCCAGCTCACCATCACCACCGACGTCGAGAACTACC
CCGGCTTCCGCGACGTGATCCAGGGTCCCTGGCTGATGCAGGAAATGCAGGCCCAGGCCGAACACGTCGGCACCCGCATG
ATGTGGGACACGATCCTCGAGGTCAGCCTCGATGGCTCGCCGTTCCGCGCCGTGGGCGACAGCGGCGACATCTACGAAGG
CGACGTGCTGGTCATCGCCACCGGCGCCCAGGCAAAGTGGCTCGGCGTGCCGGGCGAGCAGGAGTTTTCAGGCAAGGGCG
TTTCGGCCTGCGCCACCTGCGATGGGTTCTTCTATCGCGGCAAGAAGGTCGTCGTGATCGGCGGCGGCAACACCGCGGTC
GAGGAGGCGCTCTACCTCACCAACCATTCGCCCGACGTGACCCTGATCCACCGCCGCGACAGCCTGCGCGCCGAGAAGAT
CCTGCAGGACCGTCTCTTCGCCCATCCCAACGTCAAGGTGCTGTGGAACCAGAAGGTCGACAGCTTCGTGGGCGAGGCGG
GCAAGGGCCTGACCGGCGTGAAGCTGGTCGATACGGTCACTGGCGCCGAATCCGTCGTCGAAACCGACGGCGCCTTCGTT
GCCATCGGCCACGCGCCGGCCACCGAATTGTTCAAGGGCAAGCTCGAACTCGACGAGAGCGGCTACATCGTCGTTCAGCC
CGGCACGCCCAAGACCGCGATCCCGGGCGTCTTCGCATGCGGTGACGTCATGGATCACACCTATCGCCAGGCGGTTACCG
CTGCCGGAACGGGCTGCATGGCGGCGCTCGACGCGGAACGCTTCCTCGCCGAACTGGACTTCAAGGCCGCACAGGCCGTT
ATCGCGTAA

Upstream 100 bases:

>100_bases
CGGATAGCTGCGGAAAAAGCGGGGCGGGCGGACTCGCTTTTGGCTCCGGCGCCGCTTATCTCGCCTGCCGACGGCCAGCC
TGCCCGTTGGAGGAGTTTCC

Downstream 100 bases:

>100_bases
GCGCTTCGACCAGCCGCGCGTGGAGCCATTCGCGCGCGGCCTCGTCGGAGAAGCTGTGCGATGCGCTGTCGATCCGCGCG
ATGCGCGGGTCTTCGCCGCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MATTHKTRMLIIGSGPAGLSAAIYGARAGMEPIVVQGLQPGGQLTITTDVENYPGFRDVIQGPWLMQEMQAQAEHVGTRM
MWDTILEVSLDGSPFRAVGDSGDIYEGDVLVIATGAQAKWLGVPGEQEFSGKGVSACATCDGFFYRGKKVVVIGGGNTAV
EEALYLTNHSPDVTLIHRRDSLRAEKILQDRLFAHPNVKVLWNQKVDSFVGEAGKGLTGVKLVDTVTGAESVVETDGAFV
AIGHAPATELFKGKLELDESGYIVVQPGTPKTAIPGVFACGDVMDHTYRQAVTAAGTGCMAALDAERFLAELDFKAAQAV
IA

Sequences:

>Translated_322_residues
MATTHKTRMLIIGSGPAGLSAAIYGARAGMEPIVVQGLQPGGQLTITTDVENYPGFRDVIQGPWLMQEMQAQAEHVGTRM
MWDTILEVSLDGSPFRAVGDSGDIYEGDVLVIATGAQAKWLGVPGEQEFSGKGVSACATCDGFFYRGKKVVVIGGGNTAV
EEALYLTNHSPDVTLIHRRDSLRAEKILQDRLFAHPNVKVLWNQKVDSFVGEAGKGLTGVKLVDTVTGAESVVETDGAFV
AIGHAPATELFKGKLELDESGYIVVQPGTPKTAIPGVFACGDVMDHTYRQAVTAAGTGCMAALDAERFLAELDFKAAQAV
IA
>Mature_321_residues
ATTHKTRMLIIGSGPAGLSAAIYGARAGMEPIVVQGLQPGGQLTITTDVENYPGFRDVIQGPWLMQEMQAQAEHVGTRMM
WDTILEVSLDGSPFRAVGDSGDIYEGDVLVIATGAQAKWLGVPGEQEFSGKGVSACATCDGFFYRGKKVVVIGGGNTAVE
EALYLTNHSPDVTLIHRRDSLRAEKILQDRLFAHPNVKVLWNQKVDSFVGEAGKGLTGVKLVDTVTGAESVVETDGAFVA
IGHAPATELFKGKLELDESGYIVVQPGTPKTAIPGVFACGDVMDHTYRQAVTAAGTGCMAALDAERFLAELDFKAAQAVI
A

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=54.7169811320755, Blast_Score=340, Evalue=6e-95,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=33.4426229508197, Blast_Score=145, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=44.0894568690096, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=42.5867507886435, Blast_Score=264, Evalue=1e-71,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34084; Mature: 33953

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTHKTRMLIIGSGPAGLSAAIYGARAGMEPIVVQGLQPGGQLTITTDVENYPGFRDVI
CCCCCCEEEEEEECCCCCCHHEEHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCHHHHH
QGPWLMQEMQAQAEHVGTRMMWDTILEVSLDGSPFRAVGDSGDIYEGDVLVIATGAQAKW
CCCHHHHHHHHHHHHHCHHHHHHHEEEEEECCCCCEEECCCCCEEECCEEEEEECCCEEE
LGVPGEQEFSGKGVSACATCDGFFYRGKKVVVIGGGNTAVEEALYLTNHSPDVTLIHRRD
ECCCCCCCCCCCCCEEEEECCCCEECCCEEEEEECCCHHHHHEEEEECCCCCEEEEECCC
SLRAEKILQDRLFAHPNVKVLWNQKVDSFVGEAGKGLTGVKLVDTVTGAESVVETDGAFV
CHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCHHHEECCCCEE
AIGHAPATELFKGKLELDESGYIVVQPGTPKTAIPGVFACGDVMDHTYRQAVTAAGTGCM
EECCCCHHHHHCCCEEECCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCHH
AALDAERFLAELDFKAAQAVIA
HHHHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure 
ATTHKTRMLIIGSGPAGLSAAIYGARAGMEPIVVQGLQPGGQLTITTDVENYPGFRDVI
CCCCCEEEEEEECCCCCCHHEEHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCHHHHH
QGPWLMQEMQAQAEHVGTRMMWDTILEVSLDGSPFRAVGDSGDIYEGDVLVIATGAQAKW
CCCHHHHHHHHHHHHHCHHHHHHHEEEEEECCCCCEEECCCCCEEECCEEEEEECCCEEE
LGVPGEQEFSGKGVSACATCDGFFYRGKKVVVIGGGNTAVEEALYLTNHSPDVTLIHRRD
ECCCCCCCCCCCCCEEEEECCCCEECCCEEEEEECCCHHHHHEEEEECCCCCEEEEECCC
SLRAEKILQDRLFAHPNVKVLWNQKVDSFVGEAGKGLTGVKLVDTVTGAESVVETDGAFV
CHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCHHHEECCCCEE
AIGHAPATELFKGKLELDESGYIVVQPGTPKTAIPGVFACGDVMDHTYRQAVTAAGTGCM
EECCCCHHHHHCCCEEECCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCHH
AALDAERFLAELDFKAAQAVIA
HHHHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA