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The map label for this gene is dnaX [H]

Identifier: 87199957

GI number: 87199957

Start: 2055596

End: 2056552

Strand: Reverse

Name: dnaX [H]

Synonym: Saro_1940

Alternate gene names: 87199957

Gene position: 2056552-2055596 (Counterclockwise)

Preceding gene: 87199958

Following gene: 87199956

Centisome position: 57.74

GC content: 66.46

Gene sequence:

>957_bases
ATGATCGGGCACGACGAAGCCTGGCGCGCTTGGCGTTCAGCCATGGCGGGCCCGCGCATGCATCACGGATGGATACTCGC
GGGGCGCGAGGGGCTGGGCAAGGCGACATTCGCGCGTGCGGCCGCAGCCGAACTCGTTTCCGAGGCAGACGTCCCGCAAC
CTCCGGTCGACATGCACCCCGACATTCTCACGCTGTCGCCGCTTCCCGCAAGCGAGGACGAAGCGAAGAAGCGGGACGAA
GGCAAGCCCTACCTGACCAAGCGCAACATTTCCGTTGATCAGGTGCGCGAGCTCCAGCGCCGGCTCACGACGCGACCGAC
GCTGGGGAGGAGGAGGGCCGTCATCATCGACGCGGCTGACCAGCTCGAAAAGAGTGCGGTCAATGCCTTGCTCAAGAGTC
TTGAGGAACCCCCTGAAGGAACGTTCTTCCTACTCGTGGTCCACGCGCTGGGCCGGCTTCTCCCAACGGTGCGTTCGCGT
TGCCTTGTGGTGCGTTTCCAGACCTTGAGCGACGCGGACGTGGCGCGTGCGCTGGATGAAGCGGCACCCGGGCTCGACAG
CGACACGCGCCGGGCGGCATTGGCGGTGGCCGGGGGATCGCCCGGAGCCGCGCTTGCCTTCGCCGAACAGGACCTGGGCA
AGGCCCAGGCGGTCTTTGCGGCGCTGTTGGACCAGGGTGATCCGGACCTGTCGCTTCGCGGCGCGCTTTCCGGCGTGATT
GGCGCCCGACCCGACCGCGAACGGCAACTCGCTGCGATCGAGGCCGCGCGGATGACGGTCGTGCACGCGCTCGACCGGGC
CGACGATCGGACCAGGCTCAAGCTGGTCGAAGCGCATGTAAAGCTTGTCCGGCTTGCCGGCGAAGCGCCGATCTACAACT
TCGACCCAGGTATGCTGATGTTGGAAATCGGCTCCTTGCTGGCATCGGCTGCGCCGACTAGGGAAGGCGCACGATAA

Upstream 100 bases:

>100_bases
TCGCCGAGCAGGAACCCGACCGGTTCGCCGTTGTCGACGCTGAAGGATCGCCGGAAGAAGTTCATGCCCGGGTCACTGCG
GCCATCGACAAGGCGTTGGC

Downstream 100 bases:

>100_bases
GCATCAGATTCCGGTTACGAAAGCGAGCGGCCCGATGGGCGAACCCTTCTACATCACCACTGCCATCTCCTACCCCAACG
GCAAGCCGCATATCGGCCAT

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIGHDEAWRAWRSAMAGPRMHHGWILAGREGLGKATFARAAAAELVSEADVPQPPVDMHPDILTLSPLPASEDEAKKRDE
GKPYLTKRNISVDQVRELQRRLTTRPTLGRRRAVIIDAADQLEKSAVNALLKSLEEPPEGTFFLLVVHALGRLLPTVRSR
CLVVRFQTLSDADVARALDEAAPGLDSDTRRAALAVAGGSPGAALAFAEQDLGKAQAVFAALLDQGDPDLSLRGALSGVI
GARPDRERQLAAIEAARMTVVHALDRADDRTRLKLVEAHVKLVRLAGEAPIYNFDPGMLMLEIGSLLASAAPTREGAR

Sequences:

>Translated_318_residues
MIGHDEAWRAWRSAMAGPRMHHGWILAGREGLGKATFARAAAAELVSEADVPQPPVDMHPDILTLSPLPASEDEAKKRDE
GKPYLTKRNISVDQVRELQRRLTTRPTLGRRRAVIIDAADQLEKSAVNALLKSLEEPPEGTFFLLVVHALGRLLPTVRSR
CLVVRFQTLSDADVARALDEAAPGLDSDTRRAALAVAGGSPGAALAFAEQDLGKAQAVFAALLDQGDPDLSLRGALSGVI
GARPDRERQLAAIEAARMTVVHALDRADDRTRLKLVEAHVKLVRLAGEAPIYNFDPGMLMLEIGSLLASAAPTREGAR
>Mature_318_residues
MIGHDEAWRAWRSAMAGPRMHHGWILAGREGLGKATFARAAAAELVSEADVPQPPVDMHPDILTLSPLPASEDEAKKRDE
GKPYLTKRNISVDQVRELQRRLTTRPTLGRRRAVIIDAADQLEKSAVNALLKSLEEPPEGTFFLLVVHALGRLLPTVRSR
CLVVRFQTLSDADVARALDEAAPGLDSDTRRAALAVAGGSPGAALAFAEQDLGKAQAVFAALLDQGDPDLSLRGALSGVI
GARPDRERQLAAIEAARMTVVHALDRADDRTRLKLVEAHVKLVRLAGEAPIYNFDPGMLMLEIGSLLASAAPTREGAR

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=185, Percent_Identity=26.4864864864865, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 34247; Mature: 34247

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGHDEAWRAWRSAMAGPRMHHGWILAGREGLGKATFARAAAAELVSEADVPQPPVDMHP
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
DILTLSPLPASEDEAKKRDEGKPYLTKRNISVDQVRELQRRLTTRPTLGRRRAVIIDAAD
CEEEECCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHH
QLEKSAVNALLKSLEEPPEGTFFLLVVHALGRLLPTVRSRCLVVRFQTLSDADVARALDE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHH
AAPGLDSDTRRAALAVAGGSPGAALAFAEQDLGKAQAVFAALLDQGDPDLSLRGALSGVI
HCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
GARPDRERQLAAIEAARMTVVHALDRADDRTRLKLVEAHVKLVRLAGEAPIYNFDPGMLM
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHH
LEIGSLLASAAPTREGAR
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIGHDEAWRAWRSAMAGPRMHHGWILAGREGLGKATFARAAAAELVSEADVPQPPVDMHP
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
DILTLSPLPASEDEAKKRDEGKPYLTKRNISVDQVRELQRRLTTRPTLGRRRAVIIDAAD
CEEEECCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHH
QLEKSAVNALLKSLEEPPEGTFFLLVVHALGRLLPTVRSRCLVVRFQTLSDADVARALDE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHH
AAPGLDSDTRRAALAVAGGSPGAALAFAEQDLGKAQAVFAALLDQGDPDLSLRGALSGVI
HCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
GARPDRERQLAAIEAARMTVVHALDRADDRTRLKLVEAHVKLVRLAGEAPIYNFDPGMLM
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHH
LEIGSLLASAAPTREGAR
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]