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The map label for this gene is regA [H]

Identifier: 87199897

GI number: 87199897

Start: 1983088

End: 1984122

Strand: Reverse

Name: regA [H]

Synonym: Saro_1880

Alternate gene names: 87199897

Gene position: 1984122-1983088 (Counterclockwise)

Preceding gene: 87199902

Following gene: 87199893

Centisome position: 55.71

GC content: 66.09

Gene sequence:

>1035_bases
ATGAACGACGGCCCCATCAGCGACGGCAAGGCACCAGCAAAGATTAGGAACATTGCGGAGCTGGCGCGAATGGCCGGCGT
TTCCGCAGGTACCGTGTCGCGCGCGCTGGCCGACAAGGAGCTGGTCAACAAGGAAACGCGCGAACGCATCCAGGCGCTCG
CCCGGGAACACGGCTTCCGTCCGAACCAGATGGCGCGCCGCCTCCGCACACAGAAGACTGGTGTGATCGGCGTGGTCATC
CCGCTGGGGCACGAACGACGGCAGCATATCTCCGACCCGTTCTTCATGACGCTGTTCGGCTACCTGGCAGACGAACTGAC
CGAGAGCGGGCACGACCTGATGCTGTCCCGCGTCATTCCGGGCGATGACGAATGGCTTGATCGCATTGTCGATTCCGGAA
TGCTCGACGGGGCACTGGTCATCGGGCAGTCCAACCAGTTCGAAGTCATCGAACGGGTGGCACGGCACTATCGCCCGCTG
GTGGTCTGGGGCAGCCATCGCGAAGGCCAGGCCCAGTGCACGGTCGGCGTGGACAACGCCGCGGGCGGACGCCTCGCCGC
GCAGCGCCTCCTTGCCCGGGGCGCCAAGCGCCTGGCGTTCTTCGGCGACACCAATGGCCCGGAGATCGCGGAACGCCTTG
CCGGCGTGGAGCGCGCGGTGGTCAACGCCCCCGACGTGTCGCTTCGAGCCTATCCGACCCATCTCGCCAGCGATGAAATG
GCGAACCAGATCGCAGCCCATCTCGACGAACTGGGAAGTGCCATCGACGGCATCGTCTGCGCGTCCGACATGATCGCGAT
GACGACGATCCGCATTCTGCACGAACGCGGCGTCGCTGTTCCCGAGCAGGTTGCCGTTACCGGTTTCGATGACCTGCCAC
TCGCCACCCGGATGGTGCCGCAACTGACCACGGTGCGCCAGGACATCGCGGCGGGCGCGCGGGCGATGGTCGACGCCTTG
CGCCGCCGCATCGCGGGTGAGGATGCGCCCTCAACCGTGATGCAGCCGGAACTGGTCGTGCGTGAAAGCGCCTGA

Upstream 100 bases:

>100_bases
ACCCATTCCGGTTGACATGGCGGGTTGCAGCATCGCATCAGCAACCGGGGCGAAACGCGCAACCGCGCGCAGTCATGCGC
CCGCAGGACACACGGTTTCC

Downstream 100 bases:

>100_bases
TTTTCAGGCAGTAGCGCCCATCAGGCGATGGTGACCCGCTCGCCATCGAAGTTAAGCATGAACCGAGGTGCGGGGGTTCC
CCCGAAATTGCTGCGCAGCA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNDGPISDGKAPAKIRNIAELARMAGVSAGTVSRALADKELVNKETRERIQALAREHGFRPNQMARRLRTQKTGVIGVVI
PLGHERRQHISDPFFMTLFGYLADELTESGHDLMLSRVIPGDDEWLDRIVDSGMLDGALVIGQSNQFEVIERVARHYRPL
VVWGSHREGQAQCTVGVDNAAGGRLAAQRLLARGAKRLAFFGDTNGPEIAERLAGVERAVVNAPDVSLRAYPTHLASDEM
ANQIAAHLDELGSAIDGIVCASDMIAMTTIRILHERGVAVPEQVAVTGFDDLPLATRMVPQLTTVRQDIAAGARAMVDAL
RRRIAGEDAPSTVMQPELVVRESA

Sequences:

>Translated_344_residues
MNDGPISDGKAPAKIRNIAELARMAGVSAGTVSRALADKELVNKETRERIQALAREHGFRPNQMARRLRTQKTGVIGVVI
PLGHERRQHISDPFFMTLFGYLADELTESGHDLMLSRVIPGDDEWLDRIVDSGMLDGALVIGQSNQFEVIERVARHYRPL
VVWGSHREGQAQCTVGVDNAAGGRLAAQRLLARGAKRLAFFGDTNGPEIAERLAGVERAVVNAPDVSLRAYPTHLASDEM
ANQIAAHLDELGSAIDGIVCASDMIAMTTIRILHERGVAVPEQVAVTGFDDLPLATRMVPQLTTVRQDIAAGARAMVDAL
RRRIAGEDAPSTVMQPELVVRESA
>Mature_344_residues
MNDGPISDGKAPAKIRNIAELARMAGVSAGTVSRALADKELVNKETRERIQALAREHGFRPNQMARRLRTQKTGVIGVVI
PLGHERRQHISDPFFMTLFGYLADELTESGHDLMLSRVIPGDDEWLDRIVDSGMLDGALVIGQSNQFEVIERVARHYRPL
VVWGSHREGQAQCTVGVDNAAGGRLAAQRLLARGAKRLAFFGDTNGPEIAERLAGVERAVVNAPDVSLRAYPTHLASDEM
ANQIAAHLDELGSAIDGIVCASDMIAMTTIRILHERGVAVPEQVAVTGFDDLPLATRMVPQLTTVRQDIAAGARAMVDAL
RRRIAGEDAPSTVMQPELVVRESA

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=344, Percent_Identity=28.4883720930233, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=26.6081871345029, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788474, Length=342, Percent_Identity=28.6549707602339, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790194, Length=325, Percent_Identity=25.2307692307692, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790715, Length=307, Percent_Identity=23.4527687296417, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789202, Length=338, Percent_Identity=23.9644970414201, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790689, Length=327, Percent_Identity=22.0183486238532, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787948, Length=344, Percent_Identity=25.8720930232558, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789456, Length=299, Percent_Identity=24.0802675585284, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787580, Length=330, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787906, Length=314, Percent_Identity=26.4331210191083, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48994940, Length=290, Percent_Identity=21.7241379310345, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37326; Mature: 37326

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDGPISDGKAPAKIRNIAELARMAGVSAGTVSRALADKELVNKETRERIQALAREHGFR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PNQMARRLRTQKTGVIGVVIPLGHERRQHISDPFFMTLFGYLADELTESGHDLMLSRVIP
HHHHHHHHHHHCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCC
GDDEWLDRIVDSGMLDGALVIGQSNQFEVIERVARHYRPLVVWGSHREGQAQCTVGVDNA
CCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCC
AGGRLAAQRLLARGAKRLAFFGDTNGPEIAERLAGVERAVVNAPDVSLRAYPTHLASDEM
CCHHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
ANQIAAHLDELGSAIDGIVCASDMIAMTTIRILHERGVAVPEQVAVTGFDDLPLATRMVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCHHHHHHH
QLTTVRQDIAAGARAMVDALRRRIAGEDAPSTVMQPELVVRESA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHEECCC
>Mature Secondary Structure
MNDGPISDGKAPAKIRNIAELARMAGVSAGTVSRALADKELVNKETRERIQALAREHGFR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PNQMARRLRTQKTGVIGVVIPLGHERRQHISDPFFMTLFGYLADELTESGHDLMLSRVIP
HHHHHHHHHHHCCCEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCC
GDDEWLDRIVDSGMLDGALVIGQSNQFEVIERVARHYRPLVVWGSHREGQAQCTVGVDNA
CCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCC
AGGRLAAQRLLARGAKRLAFFGDTNGPEIAERLAGVERAVVNAPDVSLRAYPTHLASDEM
CCHHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
ANQIAAHLDELGSAIDGIVCASDMIAMTTIRILHERGVAVPEQVAVTGFDDLPLATRMVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECCCCCCCHHHHHHH
QLTTVRQDIAAGARAMVDALRRRIAGEDAPSTVMQPELVVRESA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]