Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 87199825

GI number: 87199825

Start: 1906678

End: 1907541

Strand: Reverse

Name: lepB [H]

Synonym: Saro_1808

Alternate gene names: 87199825

Gene position: 1907541-1906678 (Counterclockwise)

Preceding gene: 87199829

Following gene: 87199824

Centisome position: 53.56

GC content: 63.43

Gene sequence:

>864_bases
ATGACCGCGACGATGAACGACACGCCCGAAAACCAGCCCGCGCCTTTGGCAGACCCGGTGCCCGCCGTTACGCCAGCAAA
GAAGGAGAAGAAGGAGGACAGTTTCCCCGTCTTCCTCGTGAAGCTCGTTCTGGTCGTGGCGATCTTCCGCAGCTTCATCT
TCGCGCCGTTCAACATCCCGTCGGAGTCAATGCTCCCGAGACTGGAAAACGGCGATTACCTGCTGGCGGCGAAATGGCCC
TATGGCTTCAGCAAGTATTCGCTGCCGTTCAGCCTGCCGCTTATCCCCGGCCGCATCATGGCCGGGCAGCCCGAGCGTGG
TGACGTGGTCATCTTCAAGGCGCCCCCGGGCAATGATGTCGATTATATCAAGCGGGTAATCGGGATTCCCGGCGACACGG
TCCAGATGATCGGCGGCGTGCTGCACCTCAACGGCCAGGCCGTTCCCAAGGAGCGGGTCGAGGACTTCGTCATTCCGGTG
AGCCCGAACACGGACTGCCTGTCGCCCGAATTCGCCGCGACGGAAGCCGATGGTCGCCAGACCTGCCACTATCCGCAATA
CCGCGAGACGTTGCCGGGAGGGAAGACCTACAACGTACTCGACCTCGGCCAGCGCCCTGTCGACGACACCCCGCCAGTGG
TGGTCCCCGAGGGCGACCTGTTCCTGATGGGCGACAACCGCGACAATTCGATGGATAGCCGCTTCCCGGCAATGGAAGGC
GGCGGCATCGGCCTCGTTCCGCAGGAAAACCTCGTCGGCCGTGCCGCGATCATGATGTGGTCGACCGACGGCAGCGCCAA
CTGGTTCCTGCCCTGGACCTGGTTCACCGCTGCCCGCTGGAACCGGATCGGGGGCACGTTCTGA

Upstream 100 bases:

>100_bases
CGCCCGCCAAGCCGCGGTTCATCGTGCGGCAAGCTGTGCAGACGTATTTCGGAGGTGTATTATTTATACAACACACTTGA
CGAAGGGCTTCGCTGCCAAC

Downstream 100 bases:

>100_bases
GCGCGCTTGCCCCGGAGGCCAGCGCCTTCATCGCCGCCCTCACCGGTGCAGCGCCGGCGCGCCCGGAAATCTGGGCGGAA
GCCCTCACCCACGGATCGAT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTATMNDTPENQPAPLADPVPAVTPAKKEKKEDSFPVFLVKLVLVVAIFRSFIFAPFNIPSESMLPRLENGDYLLAAKWP
YGFSKYSLPFSLPLIPGRIMAGQPERGDVVIFKAPPGNDVDYIKRVIGIPGDTVQMIGGVLHLNGQAVPKERVEDFVIPV
SPNTDCLSPEFAATEADGRQTCHYPQYRETLPGGKTYNVLDLGQRPVDDTPPVVVPEGDLFLMGDNRDNSMDSRFPAMEG
GGIGLVPQENLVGRAAIMMWSTDGSANWFLPWTWFTAARWNRIGGTF

Sequences:

>Translated_287_residues
MTATMNDTPENQPAPLADPVPAVTPAKKEKKEDSFPVFLVKLVLVVAIFRSFIFAPFNIPSESMLPRLENGDYLLAAKWP
YGFSKYSLPFSLPLIPGRIMAGQPERGDVVIFKAPPGNDVDYIKRVIGIPGDTVQMIGGVLHLNGQAVPKERVEDFVIPV
SPNTDCLSPEFAATEADGRQTCHYPQYRETLPGGKTYNVLDLGQRPVDDTPPVVVPEGDLFLMGDNRDNSMDSRFPAMEG
GGIGLVPQENLVGRAAIMMWSTDGSANWFLPWTWFTAARWNRIGGTF
>Mature_286_residues
TATMNDTPENQPAPLADPVPAVTPAKKEKKEDSFPVFLVKLVLVVAIFRSFIFAPFNIPSESMLPRLENGDYLLAAKWPY
GFSKYSLPFSLPLIPGRIMAGQPERGDVVIFKAPPGNDVDYIKRVIGIPGDTVQMIGGVLHLNGQAVPKERVEDFVIPVS
PNTDCLSPEFAATEADGRQTCHYPQYRETLPGGKTYNVLDLGQRPVDDTPPVVVPEGDLFLMGDNRDNSMDSRFPAMEGG
GIGLVPQENLVGRAAIMMWSTDGSANWFLPWTWFTAARWNRIGGTF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=271, Percent_Identity=34.6863468634686, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 31555; Mature: 31424

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATMNDTPENQPAPLADPVPAVTPAKKEKKEDSFPVFLVKLVLVVAIFRSFIFAPFNIP
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
SESMLPRLENGDYLLAAKWPYGFSKYSLPFSLPLIPGRIMAGQPERGDVVIFKAPPGNDV
HHHHCCCCCCCCEEEEEECCCCCCEECCCEECCCCCCEEECCCCCCCCEEEEECCCCCCH
DYIKRVIGIPGDTVQMIGGVLHLNGQAVPKERVEDFVIPVSPNTDCLSPEFAATEADGRQ
HHHHHHHCCCCHHHHHHCEEEEECCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCC
TCHYPQYRETLPGGKTYNVLDLGQRPVDDTPPVVVPEGDLFLMGDNRDNSMDSRFPAMEG
CCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCCCCHHCCCCCCC
GGIGLVPQENLVGRAAIMMWSTDGSANWFLPWTWFTAARWNRIGGTF
CCEECCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TATMNDTPENQPAPLADPVPAVTPAKKEKKEDSFPVFLVKLVLVVAIFRSFIFAPFNIP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
SESMLPRLENGDYLLAAKWPYGFSKYSLPFSLPLIPGRIMAGQPERGDVVIFKAPPGNDV
HHHHCCCCCCCCEEEEEECCCCCCEECCCEECCCCCCEEECCCCCCCCEEEEECCCCCCH
DYIKRVIGIPGDTVQMIGGVLHLNGQAVPKERVEDFVIPVSPNTDCLSPEFAATEADGRQ
HHHHHHHCCCCHHHHHHCEEEEECCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCC
TCHYPQYRETLPGGKTYNVLDLGQRPVDDTPPVVVPEGDLFLMGDNRDNSMDSRFPAMEG
CCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEECCCCCCCHHCCCCCCC
GGIGLVPQENLVGRAAIMMWSTDGSANWFLPWTWFTAARWNRIGGTF
CCEECCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA